Small-molecule blocks malignant astrocyte proliferation and induces neuronal gene expression

Differentiation

Volumn 81, Issue 4, 2011, Pages 233-242

  Zhang, Ling ^a   Li, Peng ^b   Hsu, Tiffany ^a   Aguilar, Hector R ^c   Frantz, Doug E ^c   Schneider, Jay W ^b   Bachoo, Robert M ^b   Hsieh, Jenny ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF TEXAS AT SAN ANTONIO   (United States)

Author keywords

Astrocyte plasticity; Cancer stem cell; De differentiation; Epigenetics; Glioblastoma

Indexed keywords

ARF PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 8; HISTONE DEACETYLASE INHIBITOR; ISOXAZOLE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASTROCYTOSIS; CELL ACTIVATION; CELL CYCLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE M PHASE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; IN VITRO STUDY; MOUSE; NEURAL STEM CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; UPREGULATION;

ANIMALS; ASTROCYTES; CELL DEDIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HISTONE DEACETYLASE INHIBITORS; ISOXAZOLES; MICE; NEOPLASTIC STEM CELLS; NEUROGENESIS; NEURONS; NUCLEAR REPROGRAMMING; RECEPTOR, EPIDERMAL GROWTH FACTOR; THIOPHENES; TUMOR SUPPRESSOR PROTEINS;

EID: 79954616675     PISSN: 03014681     EISSN: 14320436     Source Type: Journal    
DOI: 10.1016/j.diff.2011.02.005     Document Type: Article

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