-
1
-
-
0033538468
-
BlyS: Member of the tumor necrosis factor family and B lymphocyte stimulator
-
Moore, P. A., Belvedere, O., Orr, A., Pieri, K., LaFleur, D. W., et al. (1999) BlyS: member of the tumor necrosis factor family and B lymphocyte stimulator. Science 285, 260-263.
-
(1999)
Science
, vol.285
, pp. 260-263
-
-
Moore, P.A.1
Belvedere, O.2
Orr, A.3
Pieri, K.4
Lafleur, D.W.5
-
2
-
-
0033532634
-
BAFF, a novel ligand of the tumor necrosis factor (TNF) family, stimulates B-cell growth
-
Schneider, P., Mackay, F., Steiner, V., Hofmann, K., Bodmer, J. L., et al. (1999) BAFF, a novel ligand of the tumor necrosis factor (TNF) family, stimulates B-cell growth. J. Exp. Med. 189, 1747-1756.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1747-1756
-
-
Schneider, P.1
MacKay, F.2
Steiner, V.3
Hofmann, K.4
Bodmer, J.L.5
-
4
-
-
0032915632
-
TALL-1 is a novel member of the TNF family that is down-regulated by mitogens
-
Shu, H.-B., Hu, W.-H., and, Johnson, H., (1999) TALL-1 is a novel member of the TNF family that is down-regulated by mitogens. J. Leuk. Biol. 65, 680-683.
-
(1999)
J. Leuk. Biol.
, vol.65
, pp. 680-683
-
-
Shu, H.-B.1
Hu, W.-H.2
Johnson, H.3
-
5
-
-
0033428703
-
Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations
-
Mackay, F., Woodcock, S. A., Lawton, P., Ambrose, C., Baetscher, M., (1999) Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J. Exp. Med. 190, 1697-1710.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1697-1710
-
-
MacKay, F.1
Woodcock, S.A.2
Lawton, P.3
Ambrose, C.4
Baetscher, M.5
-
6
-
-
0034601020
-
BAFF binds to the TNF receptor-like molecule BCMA and is important for maintaining the peripheral B cell population
-
Thompson, J. S., Schneider, P., Kalled, S. L., Wang, L., Lefevre, E. A., et al. (2000) BAFF binds to the TNF receptor-like molecule BCMA and is important for maintaining the peripheral B cell population. J. Exp. Med. 192, 129-135.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 129-135
-
-
Thompson, J.S.1
Schneider, P.2
Kalled, S.L.3
Wang, L.4
Lefevre, E.A.5
-
7
-
-
0038076049
-
Ligand-receptor binding revealed by the TNF family member TALL-1
-
Liu, Y., Hong, X., Kappler, J., Jiang, L., Zhang, R., et al. (2003) Ligand-receptor binding revealed by the TNF family member TALL-1. Nature 423, 49-56.
-
(2003)
Nature
, vol.423
, pp. 49-56
-
-
Liu, Y.1
Hong, X.2
Kappler, J.3
Jiang, L.4
Zhang, R.5
-
8
-
-
0034694088
-
BAFF mediates survival of peripheral immature B lymphocytes
-
Batten, M., Groom, J., Cachero, T. G., Qian, F., Schneider, P., et al. (2000) BAFF mediates survival of peripheral immature B lymphocytes. J. Exp. Med. 192, 1453-1465.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1453-1465
-
-
Batten, M.1
Groom, J.2
Cachero, T.G.3
Qian, F.4
Schneider, P.5
-
9
-
-
0035860559
-
An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway
-
Schiemann, B., Gommerman, J. L., Vora, K., Cachero, T. G., Shulga-Morskaya, S., et al. (2001) An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway. Science 293, 2111-2114.
-
(2001)
Science
, vol.293
, pp. 2111-2114
-
-
Schiemann, B.1
Gommerman, J.L.2
Vora, K.3
Cachero, T.G.4
Shulga-Morskaya, S.5
-
10
-
-
17944375043
-
TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease: Impaired B cell maturation in mice lacking BLyS
-
Gross, J. A., Dillon, S. R., Mudri, S., Johnston, J., Littau, A., et al. (2001) TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease: impaired B cell maturation in mice lacking BLyS. Immunity 15, 289-302.
-
(2001)
Immunity
, vol.15
, pp. 289-302
-
-
Gross, J.A.1
Dillon, S.R.2
Mudri, S.3
Johnston, J.4
Littau, A.5
-
11
-
-
13544261427
-
Selectivity of BAFF/BLyS and APRIL for binding to the TNF family receptors BAFFR/BR3 and BCMA
-
Day, E. S., Cachero, T. G., Qian, F., Sun, Y., Wen, D., et al. (2005) Selectivity of BAFF/BLyS and APRIL for binding to the TNF family receptors BAFFR/BR3 and BCMA. Biochemistry 44, 1919-1931.
-
(2005)
Biochemistry
, vol.44
, pp. 1919-1931
-
-
Day, E.S.1
Cachero, T.G.2
Qian, F.3
Sun, Y.4
Wen, D.5
-
12
-
-
77955882476
-
B-cell stage and context-dependent requirements for survival signals from BAFF and the B-cell receptor
-
Mackay, F., Figgett, W. A., Saulep, D., Lepage, M., and, Hibbs, M. L., (2010) B-cell stage and context-dependent requirements for survival signals from BAFF and the B-cell receptor. Immunol. Rev. 237, 205-225.
-
(2010)
Immunol. Rev.
, vol.237
, pp. 205-225
-
-
MacKay, F.1
Figgett, W.A.2
Saulep, D.3
Lepage, M.4
Hibbs, M.L.5
-
13
-
-
0242495115
-
Generation and characterization of LymphoStat-B, a human monoclonal antibody that antagonizes the bioactivities of B Lymphocyte Stimulator
-
Baker, K. P., Edwards, B. M., Main, S. H., Choi, G. H., Wager, R. E., et al. (2003) Generation and characterization of LymphoStat-B, a human monoclonal antibody that antagonizes the bioactivities of B Lymphocyte Stimulator. Arthritis Rheum 48, 3253-3265.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 3253-3265
-
-
Baker, K.P.1
Edwards, B.M.2
Main, S.H.3
Choi, G.H.4
Wager, R.E.5
-
14
-
-
0035860466
-
BAFF-R, a novel TNF receptor that specifically interacts with BAFF
-
Thompson, J. S., Bixler, S. A., Qian, F., Vora, K., Scott, M. L., et al. (2001) BAFF-R, a novel TNF receptor that specifically interacts with BAFF. Science 293, 2108-2111.
-
(2001)
Science
, vol.293
, pp. 2108-2111
-
-
Thompson, J.S.1
Bixler, S.A.2
Qian, F.3
Vora, K.4
Scott, M.L.5
-
15
-
-
4043146475
-
B cell-activating factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation
-
Shulga-Morskaya, S., Dobles, M., Walsh, M. E., Ng, L. G., MacKay, F., et al. (2004) B cell-activating factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation. J. Immunol. 173, 2331-2341.
-
(2004)
J. Immunol.
, vol.173
, pp. 2331-2341
-
-
Shulga-Morskaya, S.1
Dobles, M.2
Walsh, M.E.3
Ng, L.G.4
MacKay, F.5
-
16
-
-
0035007222
-
B-cell maturation protein, which binds the Tumor Necrosis Factor family members BAFF and APRIL, is dispensable for humoral immune responses
-
Xu, S., and, Lam, K.-P., (2001) B-cell maturation protein, which binds the Tumor Necrosis Factor family members BAFF and APRIL, is dispensable for humoral immune responses. Mol. Cell. Biol. 21, 4067-4074.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 4067-4074
-
-
Xu, S.1
Lam, K.-P.2
-
17
-
-
0347285357
-
BCMA is essential for the survival of long-lived bone marrow plasma cells
-
O'Connor, B. P., Raman, V. S., Erickson, L. D., Cook, W. J., Weaver, L. K., et al. (2004) BCMA is essential for the survival of long-lived bone marrow plasma cells. J. Exp. Med. 199, 91-97.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 91-97
-
-
O'Connor, B.P.1
Raman, V.S.2
Erickson, L.D.3
Cook, W.J.4
Weaver, L.K.5
-
18
-
-
44849097480
-
Cutting edge: The dependence of plasma cells and independence of memory B cells on BAFF and APRIL
-
Benson, M. J., Dillon, S. R., Castigli, E., Geha, R. S., Xu, S., et al. (2008) Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL. J. Immunol. 180, 3655-3659.
-
(2008)
J. Immunol.
, vol.180
, pp. 3655-3659
-
-
Benson, M.J.1
Dillon, S.R.2
Castigli, E.3
Geha, R.S.4
Xu, S.5
-
19
-
-
0034919939
-
Activation and accumulation of B cells in TACI-deficient mice
-
Yan, M., Wang, H., Chan, B., Roose-Girma, M., Erickson, S., et al. (2001) Activation and accumulation of B cells in TACI-deficient mice. Nature Immunol. 2, 638-643.
-
(2001)
Nature Immunol.
, vol.2
, pp. 638-643
-
-
Yan, M.1
Wang, H.2
Chan, B.3
Roose-Girma, M.4
Erickson, S.5
-
20
-
-
0037332043
-
Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor
-
Seshasayee, D., Valdez, P., Yan, M., Dixit, V. M., Tumas, D., et al. (2003) Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor. Immunity 18, 279-288.
-
(2003)
Immunity
, vol.18
, pp. 279-288
-
-
Seshasayee, D.1
Valdez, P.2
Yan, M.3
Dixit, V.M.4
Tumas, D.5
-
21
-
-
0035004320
-
Regulation of the T-independent humoral response by TACI
-
von Bulow, G.-U., van Deursen, J. M., and, Bram, R. J., (2001) Regulation of the T-independent humoral response by TACI. Immunity 14, 573-582.
-
(2001)
Immunity
, vol.14
, pp. 573-582
-
-
Von Bulow, G.-U.1
Van Deursen, J.M.2
Bram, R.J.3
-
22
-
-
67649172968
-
Transmembrane activator, calcium modulator, and cyclophilin ligand interactor drives plasma cell differentiation in LPS-activated B cells
-
e1275.
-
Ozcan, E., Garibyan, L., Lee, J. J., Bram, R. J., Lam, K. P., et al. (2009) Transmembrane activator, calcium modulator, and cyclophilin ligand interactor drives plasma cell differentiation in LPS-activated B cells. J. Allergy Clin. Immunol. 123, 1277-1286 e1275.
-
(2009)
J. Allergy Clin. Immunol.
, vol.123
, pp. 1277-1286
-
-
Ozcan, E.1
Garibyan, L.2
Lee, J.J.3
Bram, R.J.4
Lam, K.P.5
-
23
-
-
38949206321
-
TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts
-
Bossen, C., Cachero, T. G., Tardivel, A., Ingold, K., Willen, L., et al. (2008) TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts. Blood 111, 1004-1012.
-
(2008)
Blood
, vol.111
, pp. 1004-1012
-
-
Bossen, C.1
Cachero, T.G.2
Tardivel, A.3
Ingold, K.4
Willen, L.5
-
24
-
-
0035803468
-
Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen
-
Schneider, P., Takatsuka, H., Wilson, A., Mackay, F., Tardivel, A., et al. (2001) Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen. J. Exp. Med. 194, 1691-1697.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 1691-1697
-
-
Schneider, P.1
Takatsuka, H.2
Wilson, A.3
MacKay, F.4
Tardivel, A.5
-
25
-
-
18644369740
-
BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-κB2
-
Kayagaki, N., Yan, M., Seshasayee, D., Wang, H., Lee, W., et al. (2002) BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-κB2. Immunity 10, 515-524.
-
(2002)
Immunity
, vol.10
, pp. 515-524
-
-
Kayagaki, N.1
Yan, M.2
Seshasayee, D.3
Wang, H.4
Lee, W.5
-
27
-
-
33748872264
-
Development of nephritis but not sialadenitis in autoimmune-prone BAFF transgenic mice lacking marginal zone B cells
-
Fletcher, C. A., Sutherland, A. P., Groom, J. R., Batten, M. L., Ng, L. G., et al. (2006). Development of nephritis but not sialadenitis in autoimmune-prone BAFF transgenic mice lacking marginal zone B cells. Eur. J. Immunol. 36, 2504-2014.
-
(2006)
Eur. J. Immunol.
, vol.36
, pp. 2504-2014
-
-
Fletcher, C.A.1
Sutherland, A.P.2
Groom, J.R.3
Batten, M.L.4
Ng, L.G.5
-
28
-
-
10744224617
-
B lymphocyte stimulator overexpression in patients with systemic lupus erythematosus: Longitudinal observations
-
Stohl, W., Metyas, S., Tan, S. M., Cheema, G. S., Oamar, B., et al. (2003) B lymphocyte stimulator overexpression in patients with systemic lupus erythematosus: longitudinal observations. Arthritis Rheum. 48, 3475-3486.
-
(2003)
Arthritis Rheum.
, vol.48
, pp. 3475-3486
-
-
Stohl, W.1
Metyas, S.2
Tan, S.M.3
Cheema, G.S.4
Oamar, B.5
-
29
-
-
0035167632
-
A role for B lymphocyte stimulator in systemic lupus erythematosus
-
Zhang, J., Roschke, V., Baker, K. P., Wang, Z., Alarcon, G. S., et al. (2001) A role for B lymphocyte stimulator in systemic lupus erythematosus. J. Immunol. 166, 6-10.
-
(2001)
J. Immunol.
, vol.166
, pp. 6-10
-
-
Zhang, J.1
Roschke, V.2
Baker, K.P.3
Wang, Z.4
Alarcon, G.S.5
-
30
-
-
79952070370
-
Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: A randomised, placebo-controlled, phase 3 trial
-
Navarra, S. V., Guzman, R. M., Gallacher, A. E., Hall, S., Levy, R. A., et al. (2011) Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial. Lancet 377, 721-731.
-
(2011)
Lancet
, vol.377
, pp. 721-731
-
-
Navarra, S.V.1
Guzman, R.M.2
Gallacher, A.E.3
Hall, S.4
Levy, R.A.5
-
31
-
-
69749096135
-
Novel evidence-based systemic lupus erythematosus responder index
-
Furie, R. A., Petri, M. A., Wallace, D. J., Ginzler, E. M., Merrill, J. T., et al. (2009) Novel evidence-based systemic lupus erythematosus responder index. Arthritis Rheum 61, 1143-1151.
-
(2009)
Arthritis Rheum
, vol.61
, pp. 1143-1151
-
-
Furie, R.A.1
Petri, M.A.2
Wallace, D.J.3
Ginzler, E.M.4
Merrill, J.T.5
-
32
-
-
78649958105
-
Belimumab, a BLys-specific inhibitor, reduces disease activity and severe flares in seropositive SLE patients: BLISS-76 study
-
Section 74
-
Vollenhoven, R., Zamani, O., Wallace, D,., Tagzova, D., M. J., et al. (2010) Belimumab, a BLys-specific inhibitor, reduces disease activity and severe flares in seropositive SLE patients: BLISS-76 study. Ann. Rheum. Dis. 69 (Suppl 3) p. 1 Section 74.
-
(2010)
Ann. Rheum. Dis.
, vol.69
, Issue.SUPPL. 3
, pp. 1
-
-
Vollenhoven, R.1
Zamani, O.2
Wallace, D.3
Tagzova, D.4
-
33
-
-
79953223940
-
Belimumab, a BLys-specific inhibitor, reduced disease activity, flares, and steroid use in patients with seropositive systemic lupus erythematosus (SLE): BLISS-52 study
-
Section 555. 1. Accessed on April 26, 2012.
-
Navarra, S., Ilianova, E., Bae, S., Guzman, R., Tanasescu, C., et al. (2010) Belimumab, a BLys-specific inhibitor, reduced disease activity, flares, and steroid use in patients with seropositive systemic lupus erythematosus (SLE): BLISS-52 study. Ann. Rheum. Dis. 69 (Suppl 3) p. 1 Section 555. Available at:, 1. Accessed on April 26, 2012.
-
(2010)
Ann. Rheum. Dis.
, vol.69
, Issue.SUPPL. 3
, pp. 1
-
-
Navarra, S.1
Ilianova, E.2
Bae, S.3
Guzman, R.4
Tanasescu, C.5
-
34
-
-
0033883546
-
Damage in systemic lupus erythematosus and its association with corticosteroids
-
Zonana-Nacach, A., Barr, S. G., Magder, L. S., and, Petri, M., (2000) Damage in systemic lupus erythematosus and its association with corticosteroids. Arthritis Rheum 43, 1801-1808.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 1801-1808
-
-
Zonana-Nacach, A.1
Barr, S.G.2
Magder, L.S.3
Petri, M.4
-
35
-
-
0035043299
-
Treatment of lupus with corticosteroids
-
Chatham, W. W., and, Kimberly, R. P., (2001) Treatment of lupus with corticosteroids. Lupus 10, 140-147.
-
(2001)
Lupus
, vol.10
, pp. 140-147
-
-
Chatham, W.W.1
Kimberly, R.P.2
-
36
-
-
38849104447
-
Regulated expression of BAFF-binding receptors during human B cell differentiation
-
Darce, J. R., Arendt, B. K., Wu, X., and, Jelinek, D. F., (2007) Regulated expression of BAFF-binding receptors during human B cell differentiation. J. Immunol. 179, 7276-7286.
-
(2007)
J. Immunol.
, vol.179
, pp. 7276-7286
-
-
Darce, J.R.1
Arendt, B.K.2
Wu, X.3
Jelinek, D.F.4
-
37
-
-
84862002288
-
Belimumab reduces autoantibodies, normalizes low complement, and reduces select B-cell populations in patients with systemic lupus erythematosus
-
2012 Jan 24. Epub ahead of print
-
Stohl, W., Hiepe, F., Latinis, K. M., Thomas, M., Scheinberg, M. A., et al. (2012) Belimumab reduces autoantibodies, normalizes low complement, and reduces select B-cell populations in patients with systemic lupus erythematosus. Arthritis Rheum, 2012 Jan 24. Epub ahead of print.
-
(2012)
Arthritis Rheum
-
-
Stohl, W.1
Hiepe, F.2
Latinis, K.M.3
Thomas, M.4
Scheinberg, M.A.5
-
38
-
-
69749120918
-
A phase II, randomized, double-blind, placebo-controlled, dose-ranging study of belimumab in patients with active systemic lupus erythematosus
-
Wallace, D. J., Stohl, W., Furie, R. A., Lisse, J. R., McKay, J. D., et al. (2009) A phase II, randomized, double-blind, placebo-controlled, dose-ranging study of belimumab in patients with active systemic lupus erythematosus. Arthritis Rheum. 61, 1168-1178.
-
(2009)
Arthritis Rheum.
, vol.61
, pp. 1168-1178
-
-
Wallace, D.J.1
Stohl, W.2
Furie, R.A.3
Lisse, J.R.4
McKay, J.D.5
-
39
-
-
0037073930
-
Maintenance of serological memory by polyclonal activation of human memory B cells
-
Bernasconi, N. L., Traggiai, E., and, Lanzavecchia, A., (2002) Maintenance of serological memory by polyclonal activation of human memory B cells. Science 298, 2199-2202.
-
(2002)
Science
, vol.298
, pp. 2199-2202
-
-
Bernasconi, N.L.1
Traggiai, E.2
Lanzavecchia, A.3
-
41
-
-
79953191650
-
Belimumab, a BLys-specific inhibitor, significantly reduced autoantibodies and normalized low complement in patients with seropositive systemic lupus erythematosus (SLE): BLISS-52 study
-
Available at:, 1
-
Levy, R. A., Ilianova, E., Ionescu, R., Yu, C. L., Kang, Y. M., et al. (2010) Belimumab, a BLys-specific inhibitor, significantly reduced autoantibodies and normalized low complement in patients with seropositive systemic lupus erythematosus (SLE): BLISS-52 study. Ann. Rheum. Dis. 69 (Suppl 3), 1. Available at:, 1.
-
(2010)
Ann. Rheum. Dis.
, vol.69
, Issue.SUPPL. 3
, pp. 1
-
-
Levy, R.A.1
Ilianova, E.2
Ionescu, R.3
Yu, C.L.4
Kang, Y.M.5
-
43
-
-
0017193927
-
The metabolism of IgE. Studies in normal individuals and in a patient with IgE myeloma
-
Waldmann, T. A., Iio, A., Ogawa, M., McIntyre, O. R., and, Strober, W., (1976) The metabolism of IgE. Studies in normal individuals and in a patient with IgE myeloma. J. Immunol. 117, 1139-1144.
-
(1976)
J. Immunol.
, vol.117
, pp. 1139-1144
-
-
Waldmann, T.A.1
Iio, A.2
Ogawa, M.3
McIntyre, O.R.4
Strober, W.5
-
44
-
-
2942518502
-
Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches
-
Thien, M., Phan, T. G., Gardam, S., Amesbury, M., Basten, A., et al. (2004) Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches. Immunity 20, 785-798.
-
(2004)
Immunity
, vol.20
, pp. 785-798
-
-
Thien, M.1
Phan, T.G.2
Gardam, S.3
Amesbury, M.4
Basten, A.5
-
45
-
-
84862580733
-
Changes in circulating B-cell subtype counts, autoantibody levels and immunoglobulins that associate with therapeutic responsiveness in SLE to BLys protein antagonism by belimumab
-
Chatham, W., Stohl, W., Merrill, J. T., Gruhn, W., Aranow, C., et al. (2007) Changes in circulating B-cell subtype counts, autoantibody levels and immunoglobulins that associate with therapeutic responsiveness in SLE to BLys protein antagonism by belimumab. Ann. Rheum. Dis. 66 (Suppl 11), 459. Available at:.
-
(2007)
Ann. Rheum. Dis.
, vol.66
, Issue.SUPPL. 11
, pp. 459
-
-
Chatham, W.1
Stohl, W.2
Merrill, J.T.3
Gruhn, W.4
Aranow, C.5
-
46
-
-
77955140720
-
Blockade of B-cell-activating factor suppresses lupus-like syndrome in autoimmune BXSB mice
-
Ding, H., Wang, L., Wu, X., Yan, J., He, Y., et al. (2010) Blockade of B-cell-activating factor suppresses lupus-like syndrome in autoimmune BXSB mice. J. Cell. Mol. Med. 14, 1717-1725.
-
(2010)
J. Cell. Mol. Med.
, vol.14
, pp. 1717-1725
-
-
Ding, H.1
Wang, L.2
Wu, X.3
Yan, J.4
He, Y.5
-
47
-
-
84862542043
-
-
American College of Rheumatology Hotline. Available at:. Accessed on May 16, 2012.
-
Hsieh, C., (2011) "Belimumab for systemic lupus erythematosus". American College of Rheumatology Hotline. Available at:. Accessed on May 16, 2012.
-
(2011)
"belimumab for Systemic Lupus Erythematosus".
-
-
Hsieh, C.1
-
48
-
-
84860877614
-
Market snapshot: After Benlysta breakthrough, how high the sky in lupus?
-
Accessed on April 26, 2012.
-
Hayes, E., (2009) Market snapshot: after Benlysta breakthrough, how high the sky in lupus? BioPharmaToday. Available at:. Accessed on April 26, 2012.
-
(2009)
BioPharmaToday
-
-
Hayes, E.1
-
49
-
-
17344380531
-
TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease
-
Gross, J. A., Johnston, J., Mudri, S., Enselman, R., Dillon, S. R., et al. (2000) TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. Nature 404, 995-950.
-
(2000)
Nature
, vol.404
, pp. 995-950
-
-
Gross, J.A.1
Johnston, J.2
Mudri, S.3
Enselman, R.4
Dillon, S.R.5
-
50
-
-
38149114077
-
Atacicept in patients with rheumatoid arthritis: Results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating, single- and repeated-dose study
-
Tak, P. P., Thurlings, R. M., Rossier, C., Nestorov, I., Dimic, A., et al. (2008) Atacicept in patients with rheumatoid arthritis: results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating, single- and repeated-dose study. Arthritis Rheum. 58, 61-72.
-
(2008)
Arthritis Rheum.
, vol.58
, pp. 61-72
-
-
Tak, P.P.1
Thurlings, R.M.2
Rossier, C.3
Nestorov, I.4
Dimic, A.5
-
52
-
-
84862518069
-
Phase 2 study of safety and efficacy of a novel Anti-BAFF monoclonal antibody, in patients with RA treated with methotrexate (MTX)
-
Philadelphia
-
Genovese, M. C., M. E., Biagini, M., Bojin, S., and, J. Sloan-Lancaster,. (2009) Phase 2 study of safety and efficacy of a novel Anti-BAFF monoclonal antibody, in patients with RA treated with methotrexate (MTX). American College of Rheumatology National Meeting, 2009, Philadelphia.
-
(2009)
American College of Rheumatology National Meeting, 2009
-
-
Genovese, M.C.1
Biagini, M.2
Bojin, S.3
Sloan-Lancaster, J.4
-
53
-
-
43049156086
-
A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses
-
Yanaba, K., Bouaziz, J. D., Haas, K. M., Poe, J. C., Fujimoto, M., et al. (2008) A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses. Immunity 28, 639-650.
-
(2008)
Immunity
, vol.28
, pp. 639-650
-
-
Yanaba, K.1
Bouaziz, J.D.2
Haas, K.M.3
Poe, J.C.4
Fujimoto, M.5
-
54
-
-
0036795531
-
B cells regulate autoimmunity by provision of IL-10
-
Fillatreau, S., Sweenie, C. H., McGeachy, M. J., Gray, D., and, S. M. Anderton,. (2002) B cells regulate autoimmunity by provision of IL-10. Nat. Immunol. 3, 944-950.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 944-950
-
-
Fillatreau, S.1
Sweenie, C.H.2
McGeachy, M.J.3
Gray, D.4
Anderton, S.M.5
-
55
-
-
77957145333
-
What are regulatory B cells?
-
Gray, D, and, Gray, M., (2010) What are regulatory B cells? Eur. J. Immunol. 40, 2677-2679.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 2677-2679
-
-
Gray, D.1
Gray, M.2
-
56
-
-
34548223736
-
Cytokine IL-6 and IL-10 as biomarkers in systemic lupus erythematosus
-
Chun, H. Y., Chung, J. W., Kim, H. A., Yun, J. M., Jeon, J. Y., et al. (2007) Cytokine IL-6 and IL-10 as biomarkers in systemic lupus erythematosus. J. Clin. Immunol. 27, 461-466.
-
(2007)
J. Clin. Immunol.
, vol.27
, pp. 461-466
-
-
Chun, H.Y.1
Chung, J.W.2
Kim, H.A.3
Yun, J.M.4
Jeon, J.Y.5
-
57
-
-
0035576369
-
T cell costimulation by the TNF ligand BAFF
-
Huard, B., Schneider, P., Mauri, D., Tschopp, J., and, French, L. E., (2001) T cell costimulation by the TNF ligand BAFF. J. Immunol. 167, 6225-6231.
-
(2001)
J. Immunol.
, vol.167
, pp. 6225-6231
-
-
Huard, B.1
Schneider, P.2
Mauri, D.3
Tschopp, J.4
French, L.E.5
-
58
-
-
3142671331
-
B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells
-
Ng, L. G., Sutherland, A. P., Newton, R., Qian, F., Cachero, T. G., et al. (2004) B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells. J. Immunol. 173, 807-817.
-
(2004)
J. Immunol.
, vol.173
, pp. 807-817
-
-
Ng, L.G.1
Sutherland, A.P.2
Newton, R.3
Qian, F.4
Cachero, T.G.5
-
59
-
-
77949322552
-
Autoimmune disease in Lyn-deficient mice is dependent on an inflammatory environment established by IL-6
-
Tsantikos, E., Oracki, S. A., Quilici, C., Anderson, G. P., Tarlinton, D. M., et al. (2010) Autoimmune disease in Lyn-deficient mice is dependent on an inflammatory environment established by IL-6. J. Immunol. 184, 1348-1360.
-
(2010)
J. Immunol.
, vol.184
, pp. 1348-1360
-
-
Tsantikos, E.1
Oracki, S.A.2
Quilici, C.3
Anderson, G.P.4
Tarlinton, D.M.5
-
60
-
-
34547772125
-
BAFF and MyD88 signals promote a lupuslike disease independent of T cells
-
Groom, J. R., Fletcher, C. A., Walters, S. N., Grey, S. T., Watt, S. V., et al. (2007) BAFF and MyD88 signals promote a lupuslike disease independent of T cells. J. Exp. Med. 204, 1959-1971.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1959-1971
-
-
Groom, J.R.1
Fletcher, C.A.2
Walters, S.N.3
Grey, S.T.4
Watt, S.V.5
-
61
-
-
75649103234
-
How can we reduce the risk of serious infection for patients with systemic lupus erythematosus?
-
Kamen, D. L., (2009) How can we reduce the risk of serious infection for patients with systemic lupus erythematosus? Arthritis Res. Ther. 11, 129.
-
(2009)
Arthritis Res. Ther.
, vol.11
, pp. 129
-
-
Kamen, D.L.1
-
62
-
-
33845267004
-
Lupus nephritis: Toll the trigger!
-
Smith, K. D., (2006) Lupus nephritis: toll the trigger! J. Am. Soc. Nephrol. 17, 3273-3275.
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 3273-3275
-
-
Smith, K.D.1
-
63
-
-
0036098808
-
Systemic lupus erythematosus induced by Epstein-Barr virus infection
-
Verdolini, R., Bugatti, L., Giangiacomi, M., Nicolini, M., Filosa, G., et al. (2002) Systemic lupus erythematosus induced by Epstein-Barr virus infection. Br. J. Dermatol. 146, 877-881.
-
(2002)
Br. J. Dermatol.
, vol.146
, pp. 877-881
-
-
Verdolini, R.1
Bugatti, L.2
Giangiacomi, M.3
Nicolini, M.4
Filosa, G.5
|