Saffron as a source of novel acetylcholinesterase inhibitors: Molecular docking and in vitro enzymatic studies

Journal of Agricultural and Food Chemistry

Volumn 60, Issue 24, 2012, Pages 6131-6138

  Geromichalos, George D ^a   Lamari, Fotini N ^b   Papandreou, Magdalini A ^b   Trafalis, Dimitrios T ^c   Margarity, Marigoula ^b   Papageorgiou, Athanasios ^a   Sinakos, Zacharias ^d  

^a THEAGENIO CANCER HOSPITAL   (Greece)

^b UNIVERSITY OF PATRAS   (Greece)

^c UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^d ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

acetylcholinesterase; crocetin; dual inhibitors; in silico; mixed inhibition; saffron; safranal

Indexed keywords

ACETYLCHOLINESTERASE; CROCETIN; IN-SILICO; SAFFRON; SAFRANAL;

MOLECULAR MODELING;

FOOD ADDITIVES;

ACETYLCHOLINESTERASE; CAROTENOID; CHOLINESTERASE INHIBITOR; CROCETIN; PLANT EXTRACT;

ALZHEIMER DISEASE; ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; CROCUS; HUMAN; KINETICS; METABOLISM; STRUCTURE ACTIVITY RELATION;

ACETYLCHOLINESTERASE; ALZHEIMER DISEASE; BINDING SITES; CAROTENOIDS; CHOLINESTERASE INHIBITORS; CROCUS; HUMANS; KINETICS; MODELS, MOLECULAR; PLANT EXTRACTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84862534161     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf300589c     Document Type: Article

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