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Volumn 7, Issue 1, 2011, Pages 565-576

Galantamine treatment in Alzheimer's disease: Response and long-term outcome in a routine clinical setting

Author keywords

Alzheimer's disease; Cholinesterase inhibitor; Completion rates; Galantamine; K means cluster analysis; Long term treatment; Routine setting

Indexed keywords

ACETYLSALICYLIC ACID; ALPHA TOCOPHEROL; ANALGESIC AGENT; ANTACID AGENT; ANTIDEPRESSANT AGENT; ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT; ANXIOLYTIC AGENT; APOLIPOPROTEIN E4; COBALAMIN; FOLIC ACID; GALANTAMINE; GINKGO BILOBA EXTRACT; MEMANTINE; NEUROLEPTIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; NOOTROPIC AGENT;

EID: 80855166582     PISSN: 11766328     EISSN: 11782021     Source Type: Journal    
DOI: 10.2147/ndt.s24196     Document Type: Article
Times cited : (41)

References (54)
  • 1
    • 18244428862 scopus 로고    scopus 로고
    • Incidence of dementia and major subtypes in Europe: A collaborative study of population-based cohorts
    • Fratiglioni L, Launer LJ, Andersen K, et al. Incidence of dementia and major subtypes in Europe: A collaborative study of population-based cohorts. Neurology. 2000;54 Suppl 5:10-15.
    • (2000) Neurology , vol.54 , Issue.SUPPL. 5 , pp. 10-15
    • Fratiglioni, L.1    Launer, L.J.2    Andersen, K.3
  • 4
    • 0029050119 scopus 로고
    • The Consortium to Establish a Registry for Alzheimer's Disease (CERAD): Part XI. Clinical milestones in patients with Alzheimer's disease followed over 3 years
    • Galasko D, Edland SD, Morris JC, Clark C, Mohs R, Koss E. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD): Part XI. Clinical milestones in patients with Alzheimer's disease followed over 3 years. Neurology. 1995;45:1451-1455.
    • (1995) Neurology , vol.45 , pp. 1451-1455
    • Galasko, D.1    Edland, S.D.2    Morris, J.C.3    Clark, C.4    Mohs, R.5    Koss, E.6
  • 5
    • 33750329955 scopus 로고    scopus 로고
    • On behalf of the BAP Dementia Consensus Group. Clinical practice with anti-dementia drugs: A consensus statement from British Association for Psychopharmacology
    • Burns A, O'Brien J, Auriacombe S, et al; on behalf of the BAP Dementia Consensus Group. Clinical practice with anti-dementia drugs: a consensus statement from British Association for Psychopharmacology. J Psychopharmacol. 2006;20:732-755.
    • (2006) J Psychopharmacol , vol.20 , pp. 732-755
    • Burns, A.1    O'Brien, J.2    Auriacombe, S.3
  • 6
    • 0034569152 scopus 로고    scopus 로고
    • Galantamine is an allosterically potentiating ligand of the human alpha4/beta2 nAChR
    • Samochocki M, Zerlin M, Jostock R, et al. Galantamine is an allosterically potentiating ligand of the human alpha4/beta2 nAChR. Acta Neurol Scand Suppl. 2000;176:73.
    • (2000) Acta Neurol Scand Suppl , vol.176 , pp. 73
    • Samochocki, M.1    Zerlin, M.2    Jostock, R.3
  • 7
    • 33645510613 scopus 로고    scopus 로고
    • Galantamine for Alzheimer's disease and mild cognitive impairment
    • CD001747
    • Loy C, Schneider L. Galantamine for Alzheimer's disease and mild cognitive impairment. Cochrane Database Syst Rev. 2006;1:CD001747.
    • (2006) Cochrane Database Syst Rev , vol.1
    • Loy, C.1    Schneider, L.2
  • 8
    • 0034720864 scopus 로고    scopus 로고
    • 5-month, randomized, placebo-controlled trial of galantamine in AD. The Galantamine USA-10 Study Group
    • Tariot PN, Solomon PR, Morris JC, Kershaw P, Lilienfeld S, Ding C. A 5-month, randomized, placebo-controlled trial of galantamine in AD. The Galantamine USA-10 Study Group. Neurology. 2000;5: 2269-2276.
    • (2000) Neurology , vol.5 , pp. 2269-2276
    • Tariot, P.N.1    Solomon, P.R.2    Morris, J.C.3    Kershaw, P.4    Lilienfeld, S.5    Ding, C.A.6
  • 9
    • 0034720816 scopus 로고    scopus 로고
    • Galantamine in AD: A 6-month randomized, placebo-controlled trial with a 6-month extension. The Galantamine USA-1 Study Group
    • Raskind MA, Peskind ER, Wessel T, Yuan W. Galantamine in AD: A 6-month randomized, placebo-controlled trial with a 6-month extension. The Galantamine USA-1 Study Group. Neurology. 2000;54:2261-2268.
    • (2000) Neurology , vol.54 , pp. 2261-2268
    • Raskind, M.A.1    Peskind, E.R.2    Wessel, T.3    Yuan, W.4
  • 10
    • 0037222763 scopus 로고    scopus 로고
    • Correlates of response to acetylcholinesterase inhibitor therapy in Alzheimer's disease
    • KL, Herrmann N, LouLou MM. Correlates of response to acetylcholinesterase inhibitor therapy in Alzheimer's disease. J Psychiatry Neurosci. 2003;28:13-26.
    • (2003) J Psychiatry Neurosci , vol.28 , pp. 13-26
  • 11
    • 35448953471 scopus 로고    scopus 로고
    • The clinical meaningfulness of ADAS-cog changes in Alzheimer's disease patients treated with donepezil in an open-label trial
    • Rockwood K, Fay S, Gorman M, Carver D, Graham J. The clinical meaningfulness of ADAS-cog changes in Alzheimer's disease patients treated with donepezil in an open-label trial. BMC Neurology.2007;7:26.
    • (2007) BMC Neurology , vol.7 , pp. 26
    • Rockwood, K.1    Fay, S.2    Gorman, M.3    Carver, D.4    Graham, J.5
  • 12
    • 3042567016 scopus 로고    scopus 로고
    • Long-term donepezil treatment in 565 patients with Alzheimer's disease (AD2000): Randomised doubleblind trial
    • Courtney C, Farrell D, Gray R, et al. Long-term donepezil treatment in 565 patients with Alzheimer's disease (AD2000): Randomised doubleblind trial. Lancet. 2004;363:2105-2115.
    • (2004) Lancet , vol.363 , pp. 2105-2115
    • Courtney, C.1    Farrell, D.2    Gray, R.3
  • 13
    • 33646714440 scopus 로고    scopus 로고
    • 3-year study of donepezil therapy in Alzheimer's disease: Effects of early and continuous therapy
    • Winblad B, Wimo A, Engedal K, et al. 3-year study of donepezil therapy in Alzheimer's disease: Effects of early and continuous therapy. Dement Geriatr Cogn Disord. 2006;21:353-363.
    • (2006) Dement Geriatr Cogn Disord , vol.21 , pp. 353-363
    • Winblad, B.1    Wimo, A.2    Engedal, K.3    et al4
  • 14
    • 16344378591 scopus 로고    scopus 로고
    • Cognitive performance in Alzheimer's disease patients receiving rivastigmine for up to 5 years
    • Small GW, Kaufer D, Mendiondo MS, Quarg P, Spiegel R. Cognitive performance in Alzheimer's disease patients receiving rivastigmine for up to 5 years. Int J Clin Pract. 2005;59:473-477.
    • (2005) Int J Clin Pract , vol.59 , pp. 473-477
    • Small, G.W.1    Kaufer, D.2    Mendiondo, M.S.3    Quarg, P.4    Spiegel, R.5
  • 15
    • 9344231915 scopus 로고    scopus 로고
    • Long-term efficacy and safety of galantamine in patients with mild-to-moderate Alzheimer's disease: Multicenter trial
    • Pirtilla T, Wilcock G, Truyen L, Damaraju CV. Long-term efficacy and safety of galantamine in patients with mild-to-moderate Alzheimer's disease: multicenter trial. Eur J Neurol. 2004;11:734-741.
    • (2004) Eur J Neurol , vol.11 , pp. 734-741
    • Pirtilla, T.1    Wilcock, G.2    Truyen, L.3    Damaraju, C.V.4
  • 16
    • 0033998977 scopus 로고    scopus 로고
    • Long-term efficacy and safety of donepezil in the treatment of Alzheimer's disease: Final analysis of a US multicentre open-label study
    • Rogers SL, Doody RS, Pratt RD, Ieni JR. Long-term efficacy and safety of donepezil in the treatment of Alzheimer's disease: final analysis of a US multicentre open-label study. Eur Neuropsychopharmacol. 2000;10: 195-203.
    • (2000) Eur Neuropsychopharmacol , vol.10 , pp. 195-203
    • Rogers, S.L.1    Doody, R.S.2    Pratt, R.D.3    Ieni, J.R.4
  • 17
    • 0037344642 scopus 로고    scopus 로고
    • Long-term cognitive and functional decline in late onset Alzheimer's disease: Therapeutic implications
    • Holmes C, Lovestone S. Long-term cognitive and functional decline in late onset Alzheimer's disease: therapeutic implications. Age Aging. 2003;32:200-204.
    • (2003) Age Aging , vol.32 , pp. 200-204
    • Holmes, C.1    Lovestone, S.2
  • 18
    • 40549126923 scopus 로고    scopus 로고
    • Treatment of a whole population sample of Alzheimer's disease with donepezil over a 4-year period: Lessons learned
    • Lyle S, Grizzell M, Willmott S, Benbow S, Clark M, Jolley D. Treatment of a whole population sample of Alzheimer's disease with donepezil over a 4-year period: lessons learned. Dement Geriatr Cogn Disord. 2008;25:226-231.
    • (2008) Dement Geriatr Cogn Disord , vol.25 , pp. 226-231
    • Lyle, S.1    Grizzell, M.2    Willmott, S.3    Benbow, S.4    Clark, M.5    Jolley, D.6
  • 19
    • 4344675187 scopus 로고    scopus 로고
    • Five-year outcome of cholinergic treatment of Alzheimer's disease: Early response predicts prolonged time until nursing home placement, but does not alter life expectancy
    • Wallin AK, Gustafson L, Sjogren M, Wattmo C, Minthon L. Five-year outcome of cholinergic treatment of Alzheimer's disease: Early response predicts prolonged time until nursing home placement, but does not alter life expectancy. Dement Geriatr Cogn Disord. 2004;18:197-206.
    • (2004) Dement Geriatr Cogn Disord , vol.18 , pp. 197-206
    • Wallin, A.K.1    Gustafson, L.2    Sjogren, M.3    Wattmo, C.4    Minthon, L.5
  • 21
    • 33847379394 scopus 로고    scopus 로고
    • Donepezil in Alzheimer's disease: What to expect after 3 years of treatment in a routine clinical setting
    • Wallin AK, Andreasen N, Eriksson S, et al. Donepezil in Alzheimer's disease: What to expect after 3 years of treatment in a routine clinical setting. Dement Geriatr Cogn Disord. 2007;23:150-160.
    • (2007) Dement Geriatr Cogn Disord , vol.23 , pp. 150-160
    • Wallin, A.K.1    Andreasen, N.2    Eriksson, S.3
  • 23
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34:939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 24
    • 0016823810 scopus 로고
    • Mini-Mental state: A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Folstein S, McHugh PR. "Mini-Mental state": a practical method for grading the cognitive state of patients for the clinician. J Psychiatry Res. 1975;12:189-198.
    • (1975) J Psychiatry Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.2    McHugh, P.R.3
  • 25
    • 0021520020 scopus 로고
    • A new rating scale for Alzheimer's disease
    • Rosen WG, Mohs RC, Davis KL. A new rating scale for Alzheimer's disease. Am J Psychiatry. 1984;141:1356-1364.
    • (1984) Am J Psychiatry , vol.141 , pp. 1356-1364
    • Rosen, W.G.1    Mohs, R.C.2    Davis, K.L.3
  • 26
    • 0014579432 scopus 로고
    • Assessment of older people: Self-maintaining and instrumental activities of daily living
    • Lawton MP, Brody EM. Assessment of older people: Self-maintaining and instrumental activities of daily living. Gerontologist. 1969;9:179-186.
    • (1969) Gerontologist , vol.9 , pp. 179-186
    • Lawton, M.P.1    Brody, E.M.2
  • 27
    • 0028270519 scopus 로고
    • A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease
    • Knapp MJ, Knopman DS, Solomon PR, et al. A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease. JAMA. 1994;271:985-991.
    • (1994) JAMA , vol.271 , pp. 985-991
    • Knapp, M.J.1    Knopman, D.S.2    Solomon, P.R.3
  • 28
    • 0030453871 scopus 로고    scopus 로고
    • Clinical global impressions in Alzheimer's clinical trials
    • Schneider LS, Olin JT. Clinical global impressions in Alzheimer's clinical trials. Int Psychogeriatr. 1996;8:277-288.
    • (1996) Int Psychogeriatr , vol.8 , pp. 277-288
    • Schneider, L.S.1    Olin, J.T.2
  • 29
    • 0028114429 scopus 로고
    • The Clinician Interview- Based Impression (CIBI): A clinician's global change rating scale in Alzheimer's disease
    • Knopman DS, Knapp MJ, Gracon SI, Davis CS. The Clinician Interview- Based Impression (CIBI): A clinician's global change rating scale in Alzheimer's disease. Neurology. 1994;44:2315-2321.
    • (1994) Neurology , vol.44 , pp. 2315-2321
    • Knopman, D.S.1    Knapp, M.J.2    Gracon, S.I.3    Davis, C.S.4
  • 30
    • 0028262405 scopus 로고
    • A longitudinal study of Alzheimer's disease: Measurement, rate, and predictors of cognitive deterioration
    • Stern R, Mohs R, Davidson M, et al. A longitudinal study of Alzheimer's disease: measurement, rate, and predictors of cognitive deterioration. Am J Psychiatry. 1994;151:390-396.
    • (1994) Am J Psychiatry , vol.151 , pp. 390-396
    • Stern, R.1    Mohs, R.2    Davidson, M.3
  • 31
    • 0024239552 scopus 로고
    • Rates of change of common measures of impairment in senile dementia of the Alzheimer's type
    • Yesavage JA, Poulsen AB, Sheikh J, Tanke E. Rates of change of common measures of impairment in senile dementia of the Alzheimer's type. Psychopharmacol Bull. 1988;24:531-534.
    • (1988) Psychopharmacol Bull , vol.24 , pp. 531-534
    • Yesavage, J.A.1    Poulsen, A.B.2    Sheikh, J.3    Tanke, E.4
  • 32
    • 0033929448 scopus 로고    scopus 로고
    • Tracking cognitive decline in Alzheimer's disease using the Mini-Mental State Examination: A meta-analysis
    • Han L, Cole M, Bellavance F, McCusker J, Primeau F. Tracking cognitive decline in Alzheimer's disease using the Mini-Mental State Examination: a meta-analysis. Int Psychogeriatr. 2000;12: 231-247.
    • (2000) Int Psychogeriatr , vol.12 , pp. 231-247
    • Han, L.1    Cole, M.2    Bellavance, F.3    McCusker, J.4    Primeau, F.5
  • 33
    • 0035859879 scopus 로고    scopus 로고
    • A 1-year, randomized, placebo-controlled study of donepezil in patients with mild to moderate AD
    • Winblad B, Engedal K, Soininen H, et al. A 1-year, randomized, placebo-controlled study of donepezil in patients with mild to moderate AD. Neurology. 2001;57:489-495.
    • (2001) Neurology , vol.57 , pp. 489-495
    • Winblad, B.1    Engedal, K.2    Soininen, H.3
  • 35
    • 0024995599 scopus 로고
    • Longitudinal evaluation of dementia of the Alzheimer type: A comparison of 3 standardized mental status examinations
    • Salmon DP, Thal LJ, Butters N, Heindel W. Longitudinal evaluation of dementia of the Alzheimer type: a comparison of 3 standardized mental status examinations. Neurology. 1990;40:1225-1230.
    • (1990) Neurology , vol.40 , pp. 1225-1230
    • Salmon, D.P.1    Thal, L.J.2    Butters, N.3    Heindel, W.4
  • 36
    • 0034660018 scopus 로고    scopus 로고
    • Modelling Mini Mental State Examination changes in Alzheimer's disease
    • Mendiondo MS, Ashford JW, Kryscio RJ, Schmitt FA. Modelling Mini Mental State Examination changes in Alzheimer's disease. Stat Med. 2000;19:1607-1616.
    • (2000) Stat Med , vol.19 , pp. 1607-1616
    • Mendiondo, M.S.1    Ashford, J.W.2    Kryscio, R.J.3    Schmitt, F.A.4
  • 37
    • 0024273881 scopus 로고
    • Clinical predictors of course for Alzheimer patients in a longitudinal study: A preliminary report
    • Kramer-Ginsberg E, Mohs RC, Aryan M, et al. Clinical predictors of course for Alzheimer patients in a longitudinal study: a preliminary report. Psychopharmacol Bull. 1988;24(3):458-462.
    • (1988) Psychopharmacol Bull , vol.24 , Issue.3 , pp. 458-462
    • Kramer-Ginsberg, E.1    Mohs, R.C.2    Aryan, M.3
  • 38
    • 0037371279 scopus 로고    scopus 로고
    • Use of cholinesterase inhibitors in clinical practice: Evidence-based recommendations
    • Cummings JL. Use of cholinesterase inhibitors in clinical practice: evidence-based recommendations. Am J Geriatr Psychiatry. 2003;11: 131-145.
    • (2003) Am J Geriatr Psychiatry , vol.11 , pp. 131-145
    • Cummings, J.L.1
  • 39
    • 0043163594 scopus 로고    scopus 로고
    • A long-term comparison of galantamine and donepezil in the treatment of Alzheimer's disease
    • Wilcock G, Howe I, Coles H, et al. A long-term comparison of galantamine and donepezil in the treatment of Alzheimer's disease. Drugs Aging. 2003;20:777-789.
    • (2003) Drugs Aging , vol.20 , pp. 777-789
    • Wilcock, G.1    Howe, I.2    Coles, H.3
  • 40
    • 72549105935 scopus 로고    scopus 로고
    • Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease
    • Green RC, Schneider LS, Amato DA, et al. Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease. JAMA. 2009;302:2557-2564.
    • (2009) JAMA , vol.302 , pp. 2557-2564
    • Green, R.C.1    Schneider, L.S.2    Amato, D.A.3
  • 41
    • 0142059758 scopus 로고    scopus 로고
    • Clinical predictors of response to acetyl cholinesterase inhibitors: Experience from routine clinical use in Newcastle
    • Pakrasi S, Mukaetova-Ladinska EB, McKeith IG, O'Brien JT. Clinical predictors of response to acetyl cholinesterase inhibitors: experience from routine clinical use in Newcastle. Int J Geriatr Psychiatry. 2003;18: 879-886.
    • (2003) Int J Geriatr Psychiatry , vol.18 , pp. 879-886
    • Pakrasi, S.1    Mukaetova-Ladinska, E.B.2    McKeith, I.G.3    O'Brien, J.T.4
  • 42
    • 0035106966 scopus 로고    scopus 로고
    • Response of patients with Alzheimer disease to rivastigmine treatment is predicted by the rate of disease progression
    • Farlow MR, Hake A, Messina J, Hartman R, Veach J, Anand R. Response of patients with Alzheimer disease to rivastigmine treatment is predicted by the rate of disease progression. Arch Neurol. 2001;58: 417-422.
    • (2001) Arch Neurol , vol.58 , pp. 417-422
    • Farlow, M.R.1    Hake, A.2    Messina, J.3    Hartman, R.4    Veach, J.5    Anand, R.6
  • 44
    • 39749116926 scopus 로고    scopus 로고
    • Patterns of decline and evidence of subgroups in patients with Alzheimer's disease taking galantamine for up to 48 months
    • Rockwood K, Dai D, Mitnitski A. Patterns of decline and evidence of subgroups in patients with Alzheimer's disease taking galantamine for up to 48 months. Int J Geriatr Psychiatry. 2008;23:207-214.
    • (2008) Int J Geriatr Psychiatry , vol.23 , pp. 207-214
    • Rockwood, K.1    Dai, D.2    Mitnitski, A.3
  • 45
    • 77954985141 scopus 로고    scopus 로고
    • Discontinuation of cholinesterase inhibitor treatment and determinants thereof in the Netherlands: A retrospective cohort study
    • Kroger E, van Marum R, Souverein P, Egberts T. Discontinuation of cholinesterase inhibitor treatment and determinants thereof in the Netherlands: A retrospective cohort study. Drugs Aging. 2010;27: 663-675.
    • (2010) Drugs Aging , vol.27 , pp. 663-675
    • Kroger, E.1    van Marum, R.2    Souverein, P.3    Egberts, T.4
  • 46
    • 1942453361 scopus 로고    scopus 로고
    • Size of the treatment effect on cognition of cholinesterase inhibition in Alzheimer's disease
    • Rockwood K. Size of the treatment effect on cognition of cholinesterase inhibition in Alzheimer's disease. J Neurol Neurosurg Psychiatry.2005;75:677-685.
    • (2005) J Neurol Neurosurg Psychiatry , vol.75 , pp. 677-685
    • Rockwood, K.1
  • 47
    • 36549016584 scopus 로고    scopus 로고
    • The ICTUS Study: A prospective longitudinal observational study of 1,380 AD patients in Europe
    • Reynish E, Cortes F, Andrieu S, et al. The ICTUS Study: A prospective longitudinal observational study of 1,380 AD patients in Europe. Neuroepidemiology. 2007;29:29-38.
    • (2007) Neuroepidemiology , vol.29 , pp. 29-38
    • Reynish, E.1    Cortes, F.2    Andrieu, S.3
  • 48
    • 75149169206 scopus 로고    scopus 로고
    • Antidepressant use in Alzheimer's disease patients: Results of the REAL.FR cohort
    • Arbus C, Gardette V, Bui E, et al. Antidepressant use in Alzheimer's disease patients: results of the REAL.FR cohort. Int Psychogeriatr. 2010;22:120-128.
    • (2010) Int Psychogeriatr , vol.22 , pp. 120-128
    • Arbus, C.1    Gardette, V.2    Bui, E.3
  • 49
    • 68149131606 scopus 로고    scopus 로고
    • Persistence with cholinesterase inhibitor therapy for dementia: An observational administrative health database study
    • Herrmann N, Binder C, Dalziel W, Smyth S, Camacho F. Persistence with cholinesterase inhibitor therapy for dementia: an observational administrative health database study. Drugs Aging. 2009;26: 403-407.
    • (2009) Drugs Aging , vol.26 , pp. 403-407
    • Herrmann, N.1    Binder, C.2    Dalziel, W.3    Smyth, S.4    Camacho, F.5
  • 50
    • 0035103036 scopus 로고    scopus 로고
    • Open-label, multicenter, Phase 3 extension study of the safety and efficacy of donepezil in patients with Alzheimer disease
    • for the Donepezil Study Group
    • Doody RS, Geldmacher DS, Gordon B, et al; for the Donepezil Study Group. Open-label, multicenter, Phase 3 extension study of the safety and efficacy of donepezil in patients with Alzheimer disease. Arch Neurol. 2001;58:427-433.
    • (2001) Arch Neurol , vol.58 , pp. 427-433
    • Doody, R.S.1    Geldmacher, D.S.2    Gordon, B.3
  • 53
    • 23744462680 scopus 로고    scopus 로고
    • Rivastigmine and donepezil treatment in moderate to moderately-severe Alzheimer's disease over a 2-year period
    • Bullock R, Touchon J, Bergman H, et al. Rivastigmine and donepezil treatment in moderate to moderately-severe Alzheimer's disease over a 2-year period. Curr Med Res Opin. 2000;21:1317-1327.
    • (2000) Curr Med Res Opin , vol.21 , pp. 1317-1327
    • Bullock, R.1    Touchon, J.2    Bergman, H.3
  • 54
    • 0035859851 scopus 로고    scopus 로고
    • A 1-year, placebo-controlled preservation of function survival study of donepezil in AD patients
    • Mohs RC, Doody RS, Morris JC, et al. A 1-year, placebo-controlled preservation of function survival study of donepezil in AD patients. Neurology. 2001;5:481-488.
    • (2001) Neurology , vol.5 , pp. 481-488
    • Mohs, R.C.1    Doody, R.S.2    Morris, J.C.3


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