-
1
-
-
76749150110
-
Analysis of monomeric and dimeric phosphorylated forms of protein kinase R
-
Anderson E, Quartararo C, Brown RS, Shi Y, Yao X, Cole JL. 2010. Analysis of monomeric and dimeric phosphorylated forms of protein kinase R. Biochemistry 49:1217-1225.
-
(2010)
Biochemistry
, vol.49
, pp. 1217-1225
-
-
Anderson, E.1
Quartararo, C.2
Brown, R.S.3
Shi, Y.4
Yao, X.5
Cole, J.L.6
-
2
-
-
0031014063
-
Oncogenic potential of TAR RNA binding protein TRBP and its regulatory interaction with RNA-dependent protein kinase PKR
-
DOI 10.1093/emboj/16.3.611
-
Benkirane M, Neuveut C, Chun RF, Smith SM, Samuel CE, Gatignol A, Jeang KT. 1997. Oncogenic potential of TAR RNA binding protein TRBP and its regulatory interaction with RNA-dependent protein kinase PKR. EMBO J 16:611-624. (Pubitemid 27067790)
-
(1997)
EMBO Journal
, vol.16
, Issue.3
, pp. 611-624
-
-
Benkirane, M.1
Neuveut, C.2
Chun, R.F.3
Smith, S.M.4
Samuel, C.E.5
Gatignol, A.6
Jeang, K.-T.7
-
3
-
-
33746596969
-
RAX, the PKR activator, sensitizes cells to inflammatory cytokines, serum withdrawal, chemotherapy, and viral infection
-
DOI 10.1182/blood-2005-11-006817
-
Bennett RL, Blalock WL, Abtahi DM, Pan Y, Moyer SA, May WS. 2006. RAX, the PKR activator, sensitizes cells to inflammatory cytokines, serum withdrawal, chemotherapy, and viral infection. Blood 108:821-829. (Pubitemid 44154613)
-
(2006)
Blood
, vol.108
, Issue.3
, pp. 821-829
-
-
Bennett, R.L.1
Blalock, W.L.2
Abtahi, D.M.3
Pan, Y.4
Moyer, S.A.5
May, W.S.6
-
4
-
-
9244253700
-
Alpha-interferon and its effects on signalling pathways within cells
-
DOI 10.2174/1389203043379378
-
Caraglia M, Vitale G, Marra M, Budillon A, Tagliaferri P, Abbruzzese A. 2004. Alpha-interferon and its effects on signalling pathways within cells. Curr Protein Pept Sci 5:475-485. (Pubitemid 39549432)
-
(2004)
Current Protein and Peptide Science
, vol.5
, Issue.6
, pp. 475-485
-
-
Caraglia, M.1
Vitale, G.2
Marra, M.3
Budillon, A.4
Tagliaferri, P.5
Abbruzzese, A.6
-
5
-
-
69249232214
-
Emerging strategies to strengthen the anti-tumour activity of type I interferons: Overcoming survival pathways
-
Caraglia M, Marra M, Tagliaferri P, Lamberts SW, Zappavigna S, Misso G, Cavagnini F, Facchini G, Abbruzzese A, Hofland LJ, Vitale G. 2009. Emerging strategies to strengthen the anti-tumour activity of type I interferons: Overcoming survival pathways. Curr Cancer Drug Targets 9:690-704.
-
(2009)
Curr Cancer Drug Targets
, vol.9
, pp. 690-704
-
-
Caraglia, M.1
Marra, M.2
Tagliaferri, P.3
Lamberts, S.W.4
Zappavigna, S.5
Misso, G.6
Cavagnini, F.7
Facchini, G.8
Abbruzzese, A.9
Hofland, L.J.10
Vitale, G.11
-
6
-
-
18444380595
-
The double-stranded RNA-binding motif, a versatile macromolecular docking platform
-
DOI 10.1111/j.1742-4658.2005.04652.x
-
Chang KY, Ramos A. 2005. The double-stranded RNA-binding motif, a versatile macromolecular docking platform. FEBS J 272:2109-2117. (Pubitemid 40646782)
-
(2005)
FEBS Journal
, vol.272
, Issue.9
, pp. 2109-2117
-
-
Chang, K.-Y.1
Ramos, A.2
-
7
-
-
33846700754
-
Activation of PKR: an open and shut case?
-
DOI 10.1016/j.tibs.2006.12.003, PII S0968000406003288
-
Cole JL. 2007. Activation of PKR: An open and shut case? Trends Biochem Sci 32:57-62. (Pubitemid 46199193)
-
(2007)
Trends in Biochemical Sciences
, vol.32
, Issue.2
, pp. 57-62
-
-
Cole, J.L.1
-
8
-
-
0034654227
-
A new double-stranded RNA-binding protein that interacts with PKR
-
Coolidge CJ, Patton JG. 2000. A new double-stranded RNA-binding protein that interacts with PKR. Nucleic Acids Res 28:1407-1417. (Pubitemid 30142684)
-
(2000)
Nucleic Acids Research
, vol.28
, Issue.6
, pp. 1407-1417
-
-
Coolidge, C.J.1
Patton, J.G.2
-
9
-
-
0028865525
-
Double-stranded-RNA-dependent protein kinase and TAR RNA-binding protein form homo- and heterodimers in vivo
-
Cosentino GP, Venkatesan S, Serluca FC, Green SR, Mathews MB, Sonenberg N. 1995. Double-stranded-RNA-dependent protein kinase and TAR RNA-binding protein form homo- and heterodimers in vivo. Proc Natl Acad Sci USA 92:9445-9449.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 9445-9449
-
-
Cosentino, G.P.1
Venkatesan, S.2
Serluca, F.C.3
Green, S.R.4
Mathews, M.B.5
Sonenberg, N.6
-
10
-
-
0035823590
-
Two dimerization domains in the trans-activation response RNA-binding protein (TRBP) individually reverse the protein kinase R inhibition of HIV-1 long terminal repeat expression
-
Daher A, Longuet M, Dorin D, Bois F, Segeral E, Bannwarth S, Battisti PL, Purcell DF, Benarous R, Vaquero C, Meurs EF, Gatignol A. 2001. Two dimerization domains in the trans-activation response RNA-binding protein (TRBP) individually reverse the protein kinase R inhibition of HIV-1 long terminal repeat expression. J Biol Chem 276:33899-33905.
-
(2001)
J Biol Chem
, vol.276
, pp. 33899-33905
-
-
Daher, A.1
Longuet, M.2
Dorin, D.3
Bois, F.4
Segeral, E.5
Bannwarth, S.6
Battisti, P.L.7
Purcell, D.F.8
Benarous, R.9
Vaquero, C.10
Meurs, E.F.11
Gatignol, A.12
-
11
-
-
58149463628
-
TRBP control of PACT-induced phosphorylation of protein kinase R is reversed by stress
-
Daher A, Laraki G, Singh M, Melendez-Pena CE, Bannwarth S, Peters AH, Meurs EF, Braun RE, Patel RC, Gatignol A. 2009. TRBP control of PACT-induced phosphorylation of protein kinase R is reversed by stress. Mol Cell Biol 29:254-265.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 254-265
-
-
Daher, A.1
Laraki, G.2
Singh, M.3
Melendez-Pena, C.E.4
Bannwarth, S.5
Peters, A.H.6
Meurs, E.F.7
Braun, R.E.8
Patel, R.C.9
Gatignol, A.10
-
12
-
-
66249134258
-
Characterization of the TRBP domain required for dicer interaction and function in RNA interference
-
Daniels SM, Melendez-Pena CE, Scarborough RJ, Daher A, Christensen HS, El Far M, Purcell DF, Laine S, Gatignol A. 2009. Characterization of the TRBP domain required for dicer interaction and function in RNA interference. BMC Mol Biol 10:38.
-
(2009)
BMC Mol Biol
, vol.10
, pp. 38
-
-
Daniels, S.M.1
Melendez-Pena, C.E.2
Scarborough, R.J.3
Daher, A.4
Christensen, H.S.5
El Far, M.6
Purcell, D.F.7
Laine, S.8
Gatignol, A.9
-
13
-
-
79955784861
-
Effects of interferons alpha/beta on the proliferation of human micro- and macrovascular endothelial cells
-
Erdmann J, Vitale G, van Koetsveld PM, Croze E, Sprij-Mooij DM, Hofland LJ, van Eijck CH. 2011. Effects of interferons alpha/beta on the proliferation of human micro- and macrovascular endothelial cells. J Interferon Cytokine Res 31:451-458.
-
(2011)
J Interferon Cytokine Res
, vol.31
, pp. 451-458
-
-
Erdmann, J.1
Vitale, G.2
Van Koetsveld, P.M.3
Croze, E.4
Sprij-Mooij, D.M.5
Hofland, L.J.6
Van Eijck, C.H.7
-
14
-
-
33748937018
-
Antiviral action of the tumor suppressor ARF
-
DOI 10.1038/sj.emboj.7601302, PII 7601302
-
Garcia MA, Collado M, Munoz-Fontela C, Matheu A, Marcos-Villar L, Arroyo J, Esteban M, Serrano M, Rivas C. 2006a. Antiviral action of the tumor suppressor ARF. Embo J 25:4284-4292. (Pubitemid 44435226)
-
(2006)
EMBO Journal
, vol.25
, Issue.18
, pp. 4284-4292
-
-
Garcia, M.A.1
Collado, M.2
Muoz-Fontela, C.3
Matheu, A.4
Marcos-Villar, L.5
Arroyo, J.6
Esteban, M.7
Serrano, M.8
Rivas, C.9
-
15
-
-
33845627785
-
Impact of protein kinase PKR in cell biology: From antiviral to antiproliferative action
-
DOI 10.1128/MMBR.00027-06
-
Garcia MA, Gil J, Ventoso I, Guerra S, Domingo E, Rivas C, Esteban M. 2006b. Impact of protein kinase PKR in cell biology: From antiviral to antiproliferative action. Microbiol Mol Biol Rev 70:1032-1060. (Pubitemid 44958263)
-
(2006)
Microbiology and Molecular Biology Reviews
, vol.70
, Issue.4
, pp. 1032-1060
-
-
Garcia, M.A.1
Gil, J.2
Ventoso, I.3
Guerra, S.4
Domingo, E.5
Rivas, C.6
Esteban, M.7
-
16
-
-
0027105279
-
Two RNA-binding motifs in the double stranded RNA-activated protein kinase, DAI
-
Green SR, Mathews MB. 1992. Two RNA-binding motifs in the double-stranded RNA-activated protein kinase, DAI. Genes Dev 6:2478-2490. (Pubitemid 23052877)
-
(1992)
Genes and Development
, vol.6
, Issue.12 B
, pp. 2478-2490
-
-
Green, S.R.1
Mathews, M.B.2
-
17
-
-
67349188739
-
RNA dimerization promotes PKR dimerization and activation
-
Heinicke LA, Wong CJ, Lary J, Nallagatla SR, Diegelman-Parente A, Zheng X, Cole JL, Bevilacqua PC. 2009. RNA dimerization promotes PKR dimerization and activation. J Mol Biol 390:319-338.
-
(2009)
J Mol Biol
, vol.390
, pp. 319-338
-
-
Heinicke, L.A.1
Wong, C.J.2
Lary, J.3
Nallagatla, S.R.4
Diegelman-Parente, A.5
Zheng, X.6
Cole, J.L.7
Bevilacqua, P.C.8
-
18
-
-
20244378840
-
Specific interactions between Dicer-like proteins and HYL1/DRB-family dsRNA-binding proteins in Arabidopsis thaliana
-
DOI 10.1007/s11103-004-6853-5
-
Hiraguri A, Itoh R, Kondo N, Nomura Y, Aizawa D, Murai Y, Koiwa H, Seki M, Shinozaki K, Fukuhara T. 2005. Specific interactions between Dicer-like proteins and HYL1/DRB-family dsRNA-binding proteins in Arabidopsis thaliana. Plant Mol Biol 57:173-188. (Pubitemid 40572925)
-
(2005)
Plant Molecular Biology
, vol.57
, Issue.2
, pp. 173-188
-
-
Hiraguri, A.1
Itoh, R.2
Kondo, N.3
Nomura, Y.4
Aizawa, D.5
Murai, Y.6
Koiwa, H.7
Seki, M.8
Shinozaki, K.9
Fukuhara, T.10
-
19
-
-
4444248655
-
Oligomerization activity of a double-stranded RNA-binding domain
-
DOI 10.1016/j.febslet.2004.07.080, PII S0014579304009731
-
Hitti EG, Sallacz NB, Schoft VK, Jantsch MF. 2004. Oligomerization activity of a double-stranded RNA-binding domain. FEBS Lett 574:25-30. (Pubitemid 39200889)
-
(2004)
FEBS Letters
, vol.574
, Issue.1-3
, pp. 25-30
-
-
Hitti, E.G.1
Sallacz, N.B.2
Schoft, V.K.3
Jantsch, M.F.4
-
20
-
-
0023180020
-
The double-stranded RNA-dependent protein kinase is also activated by heparin
-
Hovanessian AG, Galabru J. 1987. The double-stranded RNA-dependent protein kinase is also activated by heparin. Eur J Biochem 167:467-473. (Pubitemid 17129999)
-
(1987)
European Journal of Biochemistry
, vol.167
, Issue.3
, pp. 467-473
-
-
Hovanessian, A.G.1
Galabru, J.2
-
21
-
-
0037103840
-
The C-terminal, third conserved motif of the protein activator PACT plays an essential role in the activation of double-stranded-RNA-dependent protein kinase (PKR)
-
DOI 10.1042/BJ20020204
-
Huang X, Hutchins B, Patel RC. 2002. The C-terminal, third conserved motif of the protein activator PACT plays an essential role in the activation of double-stranded-RNA-dependent protein kinase (PKR). Biochem J 366:175-186. (Pubitemid 34971816)
-
(2002)
Biochemical Journal
, vol.366
, Issue.1
, pp. 175-186
-
-
Huang, X.1
Hutchins, B.2
Patel, R.C.3
-
22
-
-
0033056848
-
RAX, a cellular activator for double-stranded RNA-dependent protein kinase during stress signaling
-
Ito T, Yang M, May WS. 1999. RAX, a cellular activator for double-stranded RNA-dependent protein kinase during stress signaling. J Biol Chem 274:15427-15432.
-
(1999)
J Biol Chem
, vol.274
, pp. 15427-15432
-
-
Ito, T.1
Yang, M.2
May, W.S.3
-
23
-
-
45849141942
-
Interactions between the double-stranded RNA-binding proteins TRBP and PACT define the Medipal domain that mediates protein-protein interactions
-
Laraki G, Clerzius G, Daher A, Melendez-Pena C, Daniels S, Gatignol A. 2008. Interactions between the double-stranded RNA-binding proteins TRBP and PACT define the Medipal domain that mediates protein-protein interactions. RNA Biol 5:92-103. (Pubitemid 351881377)
-
(2008)
RNA Biology
, vol.5
, Issue.2
, pp. 92-103
-
-
Laraki, G.1
Clerzius, G.2
Daher, A.3
Melendez-Pena, C.4
Daniels, S.5
Gatignol, A.6
-
24
-
-
3142702108
-
Merlin, a tumor suppressor, interacts with transactivation-responsive RNA-binding protein and inhibits its oncogenic activity
-
DOI 10.1074/jbc.M312083200
-
Lee JY, Kim H, Ryu CH, Kim JY, Choi BH, Lim Y, Huh PW, Kim YH, Lee KH, Jun TY, Rha HK, Kang JK, Choi CR. 2004. Merlin, a tumor suppressor, interacts with transactivation-responsive RNA-binding protein and inhibits its oncogenic activity. J Biol Chem 279:30265-30273. (Pubitemid 38937953)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.29
, pp. 30265-30273
-
-
Lee, J.Y.1
Kim, H.2
Ryu, C.H.3
Kim, J.Y.4
Choi, B.H.5
Lim, Y.6
Huh, P.-W.7
Kim, Y.-H.8
Lee, K.-H.9
Jun, T.-Y.10
Rha, H.K.11
Kang, J.-K.12
Choi, C.R.13
-
25
-
-
9644266744
-
Mechanism of PKR activation: Dimerization and kinase activation in the absence of double-stranded RNA
-
DOI 10.1016/j.jmb.2004.10.031, PII S0022283604013233
-
Lemaire PA, Lary J, Cole JL. 2005. Mechanism of PKR activation: Dimerization and kinase activation in the absence of double-stranded RNA. J Mol Biol 345:81-90. (Pubitemid 39572826)
-
(2005)
Journal of Molecular Biology
, vol.345
, Issue.1
, pp. 81-90
-
-
Lemaire, P.A.1
Lary, J.2
Cole, J.L.3
-
27
-
-
33745627468
-
Molecular basis for PKR activation by PACT or dsRNA
-
DOI 10.1073/pnas.0602317103
-
Li S, Peters GA, Ding K, Zhang X, Qin J, Sen GC. 2006. Molecular basis for PKR activation by PACT or dsRNA. Proc Natl Acad Sci USA 103:10005-10010. (Pubitemid 43993613)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.26
, pp. 10005-10010
-
-
Li, S.1
Peters, G.A.2
Ding, K.3
Zhang, X.4
Qin, J.5
Sen, G.C.6
-
28
-
-
79958118810
-
Selective leukemia cell death by activation of the double-stranded RNA-dependent protein kinase PKR
-
Li YJ, Zeng JM, Huang SF, Wang XZ, Zhao SQ, Bai WJ, Cao WX, Huang ZG, Feng WL. 2011. Selective leukemia cell death by activation of the double-stranded RNA-dependent protein kinase PKR. Int J Mol Med 28:215-222.
-
(2011)
Int J Mol Med
, vol.28
, pp. 215-222
-
-
Li, Y.J.1
Zeng, J.M.2
Huang, S.F.3
Wang, X.Z.4
Zhao, S.Q.5
Bai, W.J.6
Cao, W.X.7
Huang, Z.G.8
Feng, W.L.9
-
29
-
-
0026716255
-
Mechanism of interferon action: Identification of a RNA binding domain within the N-terminal region of the human RNA-dependent P1/eIF-2 alpha protein kinase
-
McCormack SJ, Thomis DC, Samuel CE. 1992. Mechanism of interferon action: Identification of a RNA binding domain within the N-terminal region of the human RNA-dependent P1/eIF-2 alpha protein kinase. Virology 188:47-56.
-
(1992)
Virology
, vol.188
, pp. 47-56
-
-
McCormack, S.J.1
Thomis, D.C.2
Samuel, C.E.3
-
30
-
-
0025298202
-
Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon
-
Meurs E, Chong K, Galabru J, Thomas NS, Kerr IM, Williams BR, Hovanessian AG. 1990. Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon. Cell 62:379-390.
-
(1990)
Cell
, vol.62
, pp. 379-390
-
-
Meurs, E.1
Chong, K.2
Galabru, J.3
Thomas, N.S.4
Kerr, I.M.5
Williams, B.R.6
Hovanessian, A.G.7
-
31
-
-
39449113635
-
Interaction of human tRNA-dihydrouridine synthase-2 with interferon-induced protein kinase PKR
-
DOI 10.1093/nar/gkm1129
-
Mittelstadt M, Frump A, Khuu T, Fowlkes V, Handy I, Patel CV, Patel RC. 2008. Interaction of human tRNA-dihydrouridine synthase-2 with interferon-induced protein kinase PKR. Nucleic Acids Res 36:998-1008. (Pubitemid 351267253)
-
(2008)
Nucleic Acids Research
, vol.36
, Issue.3
, pp. 998-1008
-
-
Mittelstadt, M.1
Frump, A.2
Khuu, T.3
Fowlkes, V.4
Handy, I.5
Patel, C.V.6
Patel, R.C.7
-
32
-
-
0034675856
-
A dynamically tuned double-stranded RNA binding mechanism for the activation of antiviral kinase PKR
-
Nanduri S, Rahman F, Williams BR, Qin J. 2000. A dynamically tuned double-stranded RNA binding mechanism for the activation of antiviral kinase PKR. EMBO J 19:5567-5574.
-
(2000)
EMBO J
, vol.19
, pp. 5567-5574
-
-
Nanduri, S.1
Rahman, F.2
Williams, B.R.3
Qin, J.4
-
33
-
-
0028242864
-
TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR
-
DOI 10.1073/pnas.91.11.4713
-
Park H, Davies MV, Langland JO, Chang HW, Nam YS, Tartaglia J, Paoletti E, Jacobs BL, Kaufman RJ, Venkatesan S. 1994. TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR. Proc Natl Acad Sci USA 91:4713-4717. (Pubitemid 24177719)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.11
, pp. 4713-4717
-
-
Park, H.1
Davies, M.V.2
Langland, J.O.3
Chang, H.-W.4
Nam, Y.S.5
Tartaglia, J.6
Paoletti, E.7
Jacobs, B.L.8
Kaufman, R.J.9
Venkatesan, S.10
-
34
-
-
70349577785
-
Phosphorylation of the human micro-RNA-generating complex mediates MAPK/Erk signaling
-
Paroo Z, Ye X, Chen S, Liu Q. 2009. Phosphorylation of the human micro-RNA-generating complex mediates MAPK/Erk signaling. Cell 139:112-122.
-
(2009)
Cell
, vol.139
, pp. 112-122
-
-
Paroo, Z.1
Ye, X.2
Chen, S.3
Liu, Q.4
-
35
-
-
0026686791
-
Identification of the double-stranded RNA-binding domain of the human interferon-inducible protein kinase
-
Patel RC, Sen GC. 1992. Identification of the double-stranded RNA-binding domain of the human interferon-inducible protein kinase. J Biol Chem 267:7671-7676.
-
(1992)
J Biol Chem
, vol.267
, pp. 7671-7676
-
-
Patel, R.C.1
Sen, G.C.2
-
36
-
-
0032480017
-
PACT, a protein activator of the interferon-induced protein kinase, PKR
-
DOI 10.1093/emboj/17.15.4379
-
Patel RC, Sen GC. 1998a. PACT, a protein activator of the interferon-induced protein kinase, PKR. EMBO J 17:4379-4390. (Pubitemid 28362628)
-
(1998)
EMBO Journal
, vol.17
, Issue.15
, pp. 4379-4390
-
-
Patel, R.C.1
Sen, G.C.2
-
37
-
-
0031723954
-
Requirement of PKR dimerization mediated by specific hydrophobic residues for its activation by double-stranded RNA and its antigrowth effects in yeast
-
Patel RC, Sen GC. 1998b. Requirement of PKR dimerization mediated by specific hydrophobic residues for its activation by double-stranded RNA and its antigrowth effects in yeast. Mol Cell Biol 18:7009-7019. (Pubitemid 28533021)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.12
, pp. 7009-7019
-
-
Patel, R.C.1
Sen, G.C.2
-
38
-
-
0029115903
-
The interferon-inducible double-stranded RNA-activated protein kinase self-associates in vitro and in vivo
-
Patel RC, Stanton P, McMillan NM, Williams BR, Sen GC. 1995. The interferon-inducible double-stranded RNA-activated protein kinase self-associates in vitro and in vivo. Proc Natl Acad Sci USA 92:8283-8287.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 8283-8287
-
-
Patel, R.C.1
Stanton, P.2
McMillan, N.M.3
Williams, B.R.4
Sen, G.C.5
-
39
-
-
0034531395
-
PACT, a stress-modulated cellular activator of interferon-induced double-stranded RNA-activated protein kinase, PKR
-
DOI 10.1074/jbc.M004762200
-
Patel CV, Handy I, Goldsmith T, Patel RC. 2000. PACT, a stress-modulated cellular activator of interferon-induced double-stranded RNA-activated protein kinase, PKR. J Biol Chem 275:37993-37998. (Pubitemid 32004921)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.48
, pp. 37993-37998
-
-
Patel, C.V.1
Handy, I.2
Goldsmith, T.3
Patel, R.C.4
-
40
-
-
0035012516
-
Modular structure of PACT: Distinct domains for binding and activating PKR
-
DOI 10.1128/MCB.21.6.1908-1920.2001
-
Peters GA, Hartmann R, Qin J, Sen GC. 2001. Modular structure of PACT: Distinct domains for binding and activating PKR. Mol Cell Biol 21:1908-1920. (Pubitemid 32479615)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.6
, pp. 1908-1920
-
-
Peters, G.A.1
Hartmann, R.2
Qin, J.3
Sen, G.C.4
-
41
-
-
33845746006
-
Phosphorylation of specific serine residues in the PKR activation domain of PACT is essential for its ability to mediate apoptosis
-
DOI 10.1074/jbc.M607714200
-
Peters GA, Li S, Sen GC. 2006. Phosphorylation of specific serine residues in the PKR activation domain of PACT is essential for its ability to mediate apoptosis. J Biol Chem 281:35129-35136. (Pubitemid 46036552)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.46
, pp. 35129-35136
-
-
Peters, G.A.1
Li, S.2
Sen, G.C.3
-
42
-
-
68249097024
-
Biochemical analysis of PKR activation by PACT
-
Peters GA, Dickerman B, Sen GC. 2009. Biochemical analysis of PKR activation by PACT. Biochemistry 48:7441-7447.
-
(2009)
Biochemistry
, vol.48
, pp. 7441-7447
-
-
Peters, G.A.1
Dickerman, B.2
Sen, G.C.3
-
43
-
-
33745610720
-
Dimerization of ADAR2 is mediated by the double-stranded RNA binding domain
-
DOI 10.1261/rna.2314406
-
Poulsen H, Jorgensen R, Heding A, Nielsen FC, Bonven B, Egebjerg J. 2006. Dimerization of ADAR2 is mediated by the double-stranded RNA binding domain. RNA 12:1350-1360. (Pubitemid 43990559)
-
(2006)
RNA
, vol.12
, Issue.7
, pp. 1350-1360
-
-
Poulsen, H.1
Jorgensen, R.2
Heding, A.3
Nielsen, F.C.4
Bonven, B.5
Egebjerg, J.6
-
44
-
-
0030440591
-
The regulation of the protein kinase PKR by RNA
-
DOI 10.1016/S0300-9084(97)86712-0
-
Robertson HD, Mathews MB. 1996. The regulation of the protein kinase PKR by RNA. Biochimie 78:909-914. (Pubitemid 27193109)
-
(1996)
Biochimie
, vol.78
, Issue.11-12
, pp. 909-914
-
-
Robertson, H.D.1
Mathews, M.B.2
-
45
-
-
0027418321
-
The eIF-2alpha protein kinases, regulators of translation in eukaryotes from yeasts to humans
-
Samuel CE. 1993. The eIF-2 alpha protein kinases, regulators of translation in eukaryotes from yeasts to humans. J Biol Chem 268:7603-7606. (Pubitemid 23120319)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.11
, pp. 7603-7606
-
-
Samuel, C.E.1
-
46
-
-
79958158639
-
Stress-induced phosphorylation of PACT reduces its interaction with TRBP and leads to PKR activation
-
Singh M, Castillo D, Patel CV, Patel RC. 2011. Stress-induced phosphorylation of PACT reduces its interaction with TRBP and leads to PKR activation. Biochemistry 50:4550-4560.
-
(2011)
Biochemistry
, vol.50
, pp. 4550-4560
-
-
Singh, M.1
Castillo, D.2
Patel, C.V.3
Patel, R.C.4
-
47
-
-
58149104379
-
Essential role of PACT-mediated PKR activation in tunicamycin-induced apoptosis
-
Singh M, Fowlkes V, Handy I, Patel CV, Patel RC. 2009. Essential role of PACT-mediated PKR activation in tunicamycin-induced apoptosis. J Mol Biol 385:457-468.
-
(2009)
J Mol Biol
, vol.385
, pp. 457-468
-
-
Singh, M.1
Fowlkes, V.2
Handy, I.3
Patel, C.V.4
Patel, R.C.5
-
49
-
-
25144474888
-
PKR and eIF2alpha: Integration of kinase dimerization, activation, and substrate docking
-
DOI 10.1016/j.cell.2005.09.007, PII S0092867405009189
-
Taylor SS, Haste NM, Ghosh G. 2005. PKR and eIF2alpha: Integration of kinase dimerization, activation, and substrate docking. Cell 122:823-825. (Pubitemid 41345196)
-
(2005)
Cell
, vol.122
, Issue.6
, pp. 823-825
-
-
Taylor, S.S.1
Haste, N.M.2
Ghosh, G.3
-
50
-
-
0035058685
-
Inhibitory sequences in the N-terminus of the double-stranded-RNA- dependent protein kinase, PKR, are important for regulating phosphorylation of eukaryotic initiation factor 2alpha (eIF2alpha)
-
DOI 10.1046/j.1432-1327.2001.01979.x
-
Vattem KM, Staschke KA, Zhu S, Wek RC. 2001. Inhibitory sequences in the N-terminus of the double-stranded-RNA-dependent protein kinase, PKR, are important for regulating phosphorylation of eukaryotic initiation factor 2alpha (eIF2alpha). Eur J Biochem 268:1143-1153. (Pubitemid 32328359)
-
(2001)
European Journal of Biochemistry
, vol.268
, Issue.4
, pp. 1143-1153
-
-
Vattem, K.M.1
Staschke, K.A.2
Zhu, S.3
Wek, R.C.4
-
51
-
-
84855746824
-
The PPAR-gamma agonist troglitazone antagonizes survival pathways induced by STAT-3 in recombinant interferon-beta treated pancreatic cancer cells
-
Vitale G, Zappavigna S, Marra M, Dicitore A, Meschini S, Condello M, Arancia G, Castiglioni S, Maroni P, Bendinelli P, Piccoletti R, van Koetsveld PM, Cavagnini F, Budillon A, Abbruzzese A, Hofland LJ, Caraglia M. 2012. The PPAR-gamma agonist troglitazone antagonizes survival pathways induced by STAT-3 in recombinant interferon-beta treated pancreatic cancer cells. Biotechnol Adv 30:169-184.
-
(2012)
Biotechnol Adv
, vol.30
, pp. 169-184
-
-
Vitale, G.1
Zappavigna, S.2
Marra, M.3
Dicitore, A.4
Meschini, S.5
Condello, M.6
Arancia, G.7
Castiglioni, S.8
Maroni, P.9
Bendinelli, P.10
Piccoletti, R.11
Van Koetsveld, P.M.12
Cavagnini, F.13
Budillon, A.14
Abbruzzese, A.15
Hofland, L.J.16
Caraglia, M.17
-
52
-
-
0035800333
-
Signal integration via PKR
-
Williams BR. 2001. Signal integration via PKR. Sci STKE 2001:RE2.
-
(2001)
Sci STKE
, vol.2001
-
-
Williams, B.R.1
-
53
-
-
0028797781
-
The role of the dsRNA-activated kinase, PKR, in signal transduction
-
Williams BRG. 1995. The role of the dsRNA-activated kinase, PKR, in signal transduction. Semin Virol 6:191-202.
-
(1995)
Semin Virol
, vol.6
, pp. 191-202
-
-
Williams, B.R.G.1
-
54
-
-
0035816675
-
Binding of double-stranded RNA to protein kinase PKR is required for dimerization and promotes critical autophosphorylation events in the activation loop
-
Zhang F, Romano PR, Nagamura-Inoue T, Tian B, Dever TE, Mathews MB, Ozato K, Hinnebusch AG. 2001. Binding of double-stranded RNA to protein kinase PKR is required for dimerization and promotes critical autophosphorylation events in the activation loop. J Biol Chem 276:24946-24958.
-
(2001)
J Biol Chem
, vol.276
, pp. 24946-24958
-
-
Zhang, F.1
Romano, P.R.2
Nagamura-Inoue, T.3
Tian, B.4
Dever, T.E.5
Mathews, M.B.6
Ozato, K.7
Hinnebusch, A.G.8
|