PDE5 inhibitor promotes melanin synthesis through the PKG pathway in B16 melanoma cells

Journal of Cellular Biochemistry

Volumn 113, Issue 8, 2012, Pages 2738-2743

  Zhang, Xiaodong ^a   Yan, Guirui ^a   Ji, Jun ^a,b   Wu, Jingwei ^a   Sun, Xiaoyun ^a   Shen, Jingshan ^a   Jiang, Hualiang ^a   Wang, Heyao ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

Melanin synthesis; PDE5 inhibitor; PKG; Tyrosinase

Indexed keywords

8 (4 CHLOROPHENYLTHIO) CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ISOBUTYLMETHYLXANTHINE; KT 5823; MELANIN; MONOPHENOL MONOOXYGENASE; SILDENAFIL; VARDENAFIL;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVITY; MELANOGENESIS; MELANOMA B16; MELANOMA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

CELL LINE, TUMOR; HUMANS; MELANINS; MELANOMA, EXPERIMENTAL; MONOPHENOL MONOOXYGENASE; PHOSPHODIESTERASE 5 INHIBITORS; SIGNAL TRANSDUCTION;

EID: 84862514301     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24147     Document Type: Article

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