Enzymatic treatment of whey proteins in Cow's milk results in differential inhibition of IgE-mediated mast cell activation compared to T-cell activation

International Archives of Allergy and Immunology

Volumn 159, Issue 3, 2012, Pages 263-270

  Knipping, Karen ^a,b   Van Esch, Betty C A M ^a,b   Van Ieperen Van Dijk, Adrie G ^c   Van Hoffen, Els ^c   Van Baalen, Ton ^a   Knippels, Lon M J ^a,b   Van Der Heide, Sicco ^d   Dubois, Anthony E J ^e   Garssen, Johan ^a,b   Knol, Edward F ^c  

^a DANONE RESEARCH   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d Laboratory Medicine   (Netherlands)

^e UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Cow's milk; Enzymatic hydrolysis; Mast cell degranulation; T cell activation; Whey

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN E; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; MILK PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CLONE; CELL PROLIFERATION; CONTROLLED STUDY; EAR DISEASE; ENZYME DEGRADATION; FEMALE; HEAT TREATMENT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDROLYSIS; IMMUNOGENICITY; MAST CELL; MAST CELL DEGRANULATION; MAST CELL LEUKEMIA; MILK; MILK ALLERGY; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN DEGRADATION; SWELLING; T LYMPHOCYTE ACTIVATION; ULTRAFILTRATION;

ALLERGENS; ANIMALS; BASOPHILS; CELL DEGRANULATION; CELLS, CULTURED; CHILD; EPITOPES; HUMANS; HYDROLYSIS; IMMUNE TOLERANCE; IMMUNOGLOBULIN E; LYMPHOCYTE ACTIVATION; MAST CELLS; MICE; MICE, INBRED C3H; MILK; MILK HYPERSENSITIVITY; MILK PROTEINS; PEPTIDE HYDROLASES; RATS; T-LYMPHOCYTES;

EID: 84862495441     PISSN: 10182438     EISSN: 14230097     Source Type: Journal    
DOI: 10.1159/000338007     Document Type: Article

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