Glucuronidation and methylation of procyanidin dimers B2 and 3,3″-di-O-galloyl-B2 and corresponding monomers epicatechin and 3-O-galloyl-epicatechin in mouse liver

Pharmaceutical Research

Volumn 29, Issue 3, 2012, Pages 856-865

  Shrestha, Suraj P ^a,b   Thompson, John A ^a   Wempe, Michael F ^a   Gu, Mallikarjuna ^a   Agarwal, Rajesh ^a   Agarwal, Chapla ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b XenoTech LLC   (United States)

Author keywords

Bioavailability; Flavanol; Glucuronidation; Methylation; Procyanidin

Indexed keywords

3 O GALLOYL EPICATECHIN; ADENOSINE 3' PHOSPHATE 5' PHOSPHOSULFATE; EPICATECHIN; PROCYANIDIN B2 3,3'' DI O GALLOYL ESTER; PROCYANIDIN DERIVATIVE; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE GLUCURONIC ACID; ANTINEOPLASTIC AGENT; BIFLAVONOID; CATECHIN; DRUG DERIVATIVE; EPICATECHIN GALLATE; GLUCURONIDE; GRAPE SEED EXTRACT; PROANTHOCYANIDIN; PROCYANIDIN B2;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOSOL; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG GLUCURONIDATION; DRUG HYDROLYSIS; DRUG STRUCTURE; FRAGMENTATION REACTION; IN VIVO STUDY; ION CURRENT; ION MONITORING; LIQUID CHROMATOGRAPHY; LIVER METABOLISM; LIVER MICROSOME; MALE; MASS SPECTROMETRY; METHYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SULFATION; ANIMAL; BLOOD; C57BL MOUSE; CHEMISTRY; DIMERIZATION; ISOLATION AND PURIFICATION; METABOLISM;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BIFLAVONOIDS; CATECHIN; DIMERIZATION; GLUCURONIDES; GRAPE SEED EXTRACT; MALE; METHYLATION; MICE; MICE, INBRED C57BL; MICROSOMES, LIVER; PROANTHOCYANIDINS;

EID: 84862308141     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-011-0614-3     Document Type: Article

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