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Volumn 11, Issue 6, 2012, Pages 643-653

Toll-like receptor 7 is required for effective adaptive immune responses that prevent persistent virus infection

Author keywords

[No Author keywords available]

Indexed keywords

TOLL LIKE RECEPTOR 7;

EID: 84862291971     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2012.04.016     Document Type: Article
Times cited : (61)

References (53)
  • 1
    • 0021225388 scopus 로고
    • Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence
    • R. Ahmed, A. Salmi, L.D. Butler, J.M. Chiller, and M.B. Oldstone Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence J. Exp. Med. 160 1984 521 540 (Pubitemid 14052514)
    • (1984) Journal of Experimental Medicine , vol.160 , Issue.2 , pp. 521-540
    • Ahmed, R.1    Salmi, A.2    Butler, L.D.3
  • 2
    • 1842453108 scopus 로고    scopus 로고
    • Imiquimod, a Toll-like receptor-7 agonist, induces perforin in cytotoxic T lymphocytes in vitro
    • DOI 10.1016/j.molimm.2004.01.002, PII S0161589004000409
    • A. Ambach, B. Bonnekoh, M. Nguyen, M.P. Schön, and H. Gollnick Imiquimod, a Toll-like receptor-7 agonist, induces perforin in cytotoxic T lymphocytes in vitro Mol. Immunol. 40 2004 1307 1314 (Pubitemid 38456982)
    • (2004) Molecular Immunology , vol.40 , Issue.18 , pp. 1307-1314
    • Ambach, A.1    Bonnekoh, B.2    Nguyen, M.3    Schon, M.P.4    Gollnick, H.5
  • 3
    • 32544459770 scopus 로고    scopus 로고
    • Restoring function in exhausted CD8 T cells during chronic viral infection
    • DOI 10.1038/nature04444, PII NATURE04444
    • D.L. Barber, E.J. Wherry, D. Masopust, B. Zhu, J.P. Allison, A.H. Sharpe, G.J. Freeman, and R. Ahmed Restoring function in exhausted CD8 T cells during chronic viral infection Nature 439 2006 682 687 (Pubitemid 43237609)
    • (2006) Nature , vol.439 , Issue.7077 , pp. 682-687
    • Barber, D.L.1    Wherry, E.J.2    Masopust, D.3    Zhu, B.4    Allison, J.P.5    Sharpe, A.H.6    Freeman, G.J.7    Ahmed, R.8
  • 4
    • 0034688296 scopus 로고    scopus 로고
    • Defining parameters for successful immunocytotherapy of persistent viral infection
    • DOI 10.1006/viro.1999.0074
    • D.P. Berger, D. Homann, and M.B. Oldstone Defining parameters for successful immunocytotherapy of persistent viral infection Virology 266 2000 257 263 (Pubitemid 30070630)
    • (2000) Virology , vol.266 , Issue.2 , pp. 257-263
    • Berger, D.P.1    Homann, D.2    Oldstone, M.B.A.3
  • 6
    • 78650726071 scopus 로고    scopus 로고
    • Viral replicative capacity is the primary determinant of lymphocytic choriomeningitis virus persistence and immunosuppression
    • A. Bergthaler, L. Flatz, A.N. Hegazy, S. Johnson, E. Horvath, M. Löhning, and D.D. Pinschewer Viral replicative capacity is the primary determinant of lymphocytic choriomeningitis virus persistence and immunosuppression Proc. Natl. Acad. Sci. USA 107 2010 21641 21646
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 21641-21646
    • Bergthaler, A.1    Flatz, L.2    Hegazy, A.N.3    Johnson, S.4    Horvath, E.5    Löhning, M.6    Pinschewer, D.D.7
  • 8
    • 0028873681 scopus 로고
    • Virus-induced immunosuppression: Immune system-mediated destruction of virus-infected dendritic cells results in generalized immune suppression
    • P. Borrow, C.F. Evans, and M.B. Oldstone Virus-induced immunosuppression: immune system-mediated destruction of virus-infected dendritic cells results in generalized immune suppression J. Virol. 69 1995 1059 1070
    • (1995) J. Virol. , vol.69 , pp. 1059-1070
    • Borrow, P.1    Evans, C.F.2    Oldstone, M.B.3
  • 9
    • 79952071379 scopus 로고    scopus 로고
    • Inhibition of the type i interferon antiviral response during arenavirus infection
    • P. Borrow, L. Martínez-Sobrido, and J.C. de la Torre Inhibition of the type I interferon antiviral response during arenavirus infection Viruses 2 2010 2443 2480
    • (2010) Viruses , vol.2 , pp. 2443-2480
    • Borrow, P.1    Martínez-Sobrido, L.2    De La Torre, J.C.3
  • 11
    • 80055080756 scopus 로고    scopus 로고
    • Toll-like receptor 7 controls the anti-retroviral germinal center response
    • E.P. Browne Toll-like receptor 7 controls the anti-retroviral germinal center response PLoS Pathog. 7 2011 e1002293
    • (2011) PLoS Pathog. , vol.7 , pp. 1002293
    • Browne, E.P.1
  • 12
    • 34447299235 scopus 로고    scopus 로고
    • Arenaviridae: The viruses and their replication
    • D.M. Knipe, P.M. Howley, Wolter Kluwer Lippincott Williams & Wilkins Philadelphia
    • M.J. Buchmeier, J.C. de la Torre, and C.J. Peters Arenaviridae: the viruses and their replication D.M. Knipe, P.M. Howley, Fields Virology 2007 Wolter Kluwer Lippincott Williams & Wilkins Philadelphia 1791 1827
    • (2007) Fields Virology , pp. 1791-1827
    • Buchmeier, M.J.1    De La Torre, J.C.2    Peters, C.J.3
  • 14
    • 67649217469 scopus 로고    scopus 로고
    • IL-21 is required to control chronic viral infection
    • H. Elsaesser, K. Sauer, and D.G. Brooks IL-21 is required to control chronic viral infection Science 324 2009 1569 1572
    • (2009) Science , vol.324 , pp. 1569-1572
    • Elsaesser, H.1    Sauer, K.2    Brooks, D.G.3
  • 15
    • 77749285677 scopus 로고    scopus 로고
    • How chronic viral infections impact on antigen-specific T-cell responses
    • H. Frebel, K. Richter, and A. Oxenius How chronic viral infections impact on antigen-specific T-cell responses Eur. J. Immunol. 40 2010 654 663
    • (2010) Eur. J. Immunol. , vol.40 , pp. 654-663
    • Frebel, H.1    Richter, K.2    Oxenius, A.3
  • 16
    • 77955095220 scopus 로고    scopus 로고
    • Toll-like receptor (TLR) expression on CD4+ and CD8+ T-cells in patients chronically infected with hepatitis C virus
    • T. Hammond, S. Lee, M.W. Watson, J.P. Flexman, W. Cheng, S. Fernandez, and P. Price Toll-like receptor (TLR) expression on CD4+ and CD8+ T-cells in patients chronically infected with hepatitis C virus Cell. Immunol. 264 2010 150 155
    • (2010) Cell. Immunol. , vol.264 , pp. 150-155
    • Hammond, T.1    Lee, S.2    Watson, M.W.3    Flexman, J.P.4    Cheng, W.5    Fernandez, S.6    Price, P.7
  • 17
    • 81055157812 scopus 로고    scopus 로고
    • Late interleukin-6 escalates T follicular helper cell responses and controls a chronic viral infection
    • J.A. Harker, G.M. Lewis, L. Mack, and E.I. Zuniga Late interleukin-6 escalates T follicular helper cell responses and controls a chronic viral infection Science 334 2011 825 829
    • (2011) Science , vol.334 , pp. 825-829
    • Harker, J.A.1    Lewis, G.M.2    MacK, L.3    Zuniga, E.I.4
  • 18
    • 33846937311 scopus 로고    scopus 로고
    • TLR signaling fine-tunes anti-influenza B cell responses without regulating effector T cell responses
    • A.K. Heer, A. Shamshiev, A. Donda, S. Uematsu, S. Akira, M. Kopf, and B.J. Marsland TLR signaling fine-tunes anti-influenza B cell responses without regulating effector T cell responses J. Immunol. 178 2007 2182 2191 (Pubitemid 46233416)
    • (2007) Journal of Immunology , vol.178 , Issue.4 , pp. 2182-2191
    • Heer, A.K.1    Shamshiev, A.2    Donda, A.3    Uematsu, S.4    Akira, S.5    Kopf, M.6    Marsland, B.J.7
  • 20
    • 0031713696 scopus 로고    scopus 로고
    • Evidence for an underlying CD4 helper and CD8 T-cell defect in B-cell- deficient mice: Failure to clear persistent virus infection after adoptive immunotherapy with virus-specific memory cells from μMT/μMT mice
    • D. Homann, A. Tishon, D.P. Berger, W.O. Weigle, M.G. von Herrath, and M.B. Oldstone Evidence for an underlying CD4 helper and CD8 T-cell defect in B-cell-deficient mice: failure to clear persistent virus infection after adoptive immunotherapy with virus-specific memory cells from muMT/muMT mice J. Virol. 72 1998 9208 9216 (Pubitemid 28471867)
    • (1998) Journal of Virology , vol.72 , Issue.11 , pp. 9208-9216
    • Homann, D.1    Tishon, A.2    Berger, D.P.3    Weigle, W.O.4    Von Herrath, M.G.5    Oldstone, M.B.A.6
  • 21
    • 0036570169 scopus 로고    scopus 로고
    • Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
    • V. Hornung, S. Rothenfusser, S. Britsch, A. Krug, B. Jahrsdörfer, T. Giese, S. Endres, and G. Hartmann Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides J. Immunol. 168 2002 4531 4537 (Pubitemid 34441357)
    • (2002) Journal of Immunology , vol.168 , Issue.9 , pp. 4531-4537
    • Hornung, V.1    Rothenfusser, S.2    Britsch, S.3    Krug, A.4    Jahrsdorfer, B.5    Giese, T.6    Endres, S.7    Hartmann, G.8
  • 23
    • 77949390748 scopus 로고    scopus 로고
    • Toll-like receptor agonists synergistically increase proliferation and activation of B cells by epstein-barr virus
    • S. Iskra, M. Kalla, H.J. Delecluse, W. Hammerschmidt, and A. Moosmann Toll-like receptor agonists synergistically increase proliferation and activation of B cells by epstein-barr virus J. Virol. 84 2010 3612 3623
    • (2010) J. Virol. , vol.84 , pp. 3612-3623
    • Iskra, S.1    Kalla, M.2    Delecluse, H.J.3    Hammerschmidt, W.4    Moosmann, A.5
  • 24
    • 37349031103 scopus 로고    scopus 로고
    • Lymphocytoid choriomeningitis virus activates plasmacytoid dendritic cells and induces a cytotoxic T-cell response via MyD88
    • DOI 10.1128/JVI.01640-07
    • A. Jung, H. Kato, Y. Kumagai, H. Kumar, T. Kawai, O. Takeuchi, and S. Akira Lymphocytoid choriomeningitis virus activates plasmacytoid dendritic cells and induces a cytotoxic T-cell response via MyD88 J. Virol. 82 2008 196 206 (Pubitemid 350309136)
    • (2008) Journal of Virology , vol.82 , Issue.1 , pp. 196-206
    • Jung, A.1    Kato, H.2    Kumagai, Y.3    Kumar, H.4    Kawai, T.5    Takeuchi, O.6    Akira, S.7
  • 25
    • 0035903288 scopus 로고    scopus 로고
    • Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens
    • DOI 10.1084/jem.194.6.863
    • N. Kadowaki, S. Ho, S. Antonenko, R.W. Malefyt, R.A. Kastelein, F. Bazan, and Y.J. Liu Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens J. Exp. Med. 194 2001 863 869 (Pubitemid 32983021)
    • (2001) Journal of Experimental Medicine , vol.194 , Issue.6 , pp. 863-869
    • Kadowaki, N.1    Ho, S.2    Antonenko, S.3    De Waal Malefyt, R.4    Kastelein, R.A.5    Bazan, F.6    Liu, Y.-J.7
  • 26
    • 24344478196 scopus 로고    scopus 로고
    • Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection
    • DOI 10.1084/jem.20050821
    • G.A. Kolumam, S. Thomas, L.J. Thompson, J. Sprent, and K. Murali-Krishna Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection J. Exp. Med. 202 2005 637 650 (Pubitemid 41248415)
    • (2005) Journal of Experimental Medicine , vol.202 , Issue.5 , pp. 637-650
    • Kolumam, G.A.1    Thomas, S.2    Thompson, L.J.3    Sprent, J.4    Murali-Krishna, K.5
  • 27
    • 38949117752 scopus 로고    scopus 로고
    • Differential role of TLR- and RLR-signaling in the immune responses to influenza A virus infection and vaccination
    • S. Koyama, K.J. Ishii, H. Kumar, T. Tanimoto, C. Coban, S. Uematsu, T. Kawai, and S. Akira Differential role of TLR- and RLR-signaling in the immune responses to influenza A virus infection and vaccination J. Immunol. 179 2007 4711 4720
    • (2007) J. Immunol. , vol.179 , pp. 4711-4720
    • Koyama, S.1    Ishii, K.J.2    Kumar, H.3    Tanimoto, T.4    Coban, C.5    Uematsu, S.6    Kawai, T.7    Akira, S.8
  • 28
    • 59649123419 scopus 로고    scopus 로고
    • Modulation of dendritic cell function by persistent viruses
    • B. Liu, A.M. Woltman, H.L. Janssen, and A. Boonstra Modulation of dendritic cell function by persistent viruses J. Leukoc. Biol. 85 2009 205 214
    • (2009) J. Leukoc. Biol. , vol.85 , pp. 205-214
    • Liu, B.1    Woltman, A.M.2    Janssen, H.L.3    Boonstra, A.4
  • 30
    • 84862280795 scopus 로고    scopus 로고
    • Early host responses upon in vivo infection with a plasmacytoid dendritic cell-tropic arenavirus
    • this issue
    • M. Macal, G.M. Lewins, R. Flavell, F. Kunz, J.A. Harker, and E.I. Zuniga Early host responses upon in vivo infection with a plasmacytoid dendritic cell-tropic arenavirus Cell Host Microbe 11 2012 617 630 this issue
    • (2012) Cell Host Microbe , vol.11 , pp. 617-630
    • MacAl, M.1    Lewins, G.M.2    Flavell, R.3    Kunz, F.4    Harker, J.A.5    Zuniga, E.I.6
  • 31
    • 0027971622 scopus 로고
    • + cytotoxic T-cell responses during chronic viral infection
    • M. Matloubian, R.J. Concepcion, and R. Ahmed CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection J. Virol. 68 1994 8056 8063 (Pubitemid 24362694)
    • (1994) Journal of Virology , vol.68 , Issue.12 , pp. 8056-8063
    • Matloubian, M.1    Concepcion, R.J.2    Ahmed, R.3
  • 35
    • 0036188676 scopus 로고    scopus 로고
    • Arenaviruses. II. The molecular pathogenesis of arenavirus infections. Introduction
    • M.B. Oldstone Arenaviruses. II. The molecular pathogenesis of arenavirus infections. Introduction Curr. Top. Microbiol. Immunol. 263 2002 V XII
    • (2002) Curr. Top. Microbiol. Immunol. , vol.263
    • Oldstone, M.B.1
  • 37
    • 0031975635 scopus 로고    scopus 로고
    • Virus-specific MHC class II-restricted TCR-transgenic mice: Effects on humoral and cellular immune responses after viral infection
    • DOI 10.1002/(SICI)1521-4141(199801)28:01<390::AID-IMMU390>3.0.CO;2- O
    • A. Oxenius, M.F. Bachmann, R.M. Zinkernagel, and H. Hengartner Virus-specific MHC-class II-restricted TCR-transgenic mice: effects on humoral and cellular immune responses after viral infection Eur. J. Immunol. 28 1998 390 400 (Pubitemid 28048309)
    • (1998) European Journal of Immunology , vol.28 , Issue.1 , pp. 390-400
    • Oxenius, A.1    Bachmann, M.F.2    Zinkernagel, R.M.3    Hengartner, H.4
  • 38
    • 0024307348 scopus 로고
    • Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
    • DOI 10.1038/342559a0
    • H. Pircher, K. Bürki, R. Lang, H. Hengartner, and R.M. Zinkernagel Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen Nature 342 1989 559 561 (Pubitemid 20005822)
    • (1989) Nature , vol.342 , Issue.6249 , pp. 559-561
    • Pircher, H.1    Burki, K.2    Lang, R.3    Hengartner, H.4    Zinkernagel, R.M.5
  • 39
    • 0030986358 scopus 로고    scopus 로고
    • A critical role for neutralizing-antibody-producing B cells, CD4(+) T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: Implications for adoptive immunotherapy of virus carriers
    • O. Planz, S. Ehl, E. Furrer, E. Horvath, M.A. Bründler, H. Hengartner, and R.M. Zinkernagel A critical role for neutralizing-antibody- producing B cells, CD4(+) T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: implications for adoptive immunotherapy of virus carriers Proc. Natl. Acad. Sci. USA 94 1997 6874 6879
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 6874-6879
    • Planz, O.1    Ehl, S.2    Furrer, E.3    Horvath, E.4    Bründler, M.A.5    Hengartner, H.6    Zinkernagel, R.M.7
  • 40
    • 0026088714 scopus 로고
    • Molecular basis of viral persistence: A single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with suppression of the antiviral cytotoxic T-lymphocyte response and establishment of persistence
    • M. Salvato, P. Borrow, E. Shimomaye, and M.B. Oldstone Molecular basis of viral persistence: a single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with suppression of the antiviral cytotoxic T-lymphocyte response and establishment of persistence J. Virol. 65 1991 1863 1869
    • (1991) J. Virol. , vol.65 , pp. 1863-1869
    • Salvato, M.1    Borrow, P.2    Shimomaye, E.3    Oldstone, M.B.4
  • 41
    • 73149111309 scopus 로고    scopus 로고
    • Increased expression of TLR7 in CD8(+) T cells leads to TLR7-mediated activation and accessory cell-dependent IFN-gamma production in HIV type 1 infection
    • Y. Song, Y. Zhuang, S. Zhai, D. Huang, Y. Zhang, W. Kang, X. Li, Q. Liu, Q. Yu, and Y. Sun Increased expression of TLR7 in CD8(+) T cells leads to TLR7-mediated activation and accessory cell-dependent IFN-gamma production in HIV type 1 infection AIDS Res. Hum. Retroviruses 25 2009 1287 1295
    • (2009) AIDS Res. Hum. Retroviruses , vol.25 , pp. 1287-1295
    • Song, Y.1    Zhuang, Y.2    Zhai, S.3    Huang, D.4    Zhang, Y.5    Kang, W.6    Li, X.7    Liu, Q.8    Yu, Q.9    Sun, Y.10
  • 42
    • 79952582607 scopus 로고    scopus 로고
    • Point mutation in the glycoprotein of lymphocytic choriomeningitis virus is necessary for receptor binding, dendritic cell infection, and long-term persistence
    • B.M. Sullivan, S.F. Emonet, M.J. Welch, A.M. Lee, K.P. Campbell, J.C. de la Torre, and M.B. Oldstone Point mutation in the glycoprotein of lymphocytic choriomeningitis virus is necessary for receptor binding, dendritic cell infection, and long-term persistence Proc. Natl. Acad. Sci. USA 108 2011 2969 2974
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 2969-2974
    • Sullivan, B.M.1    Emonet, S.F.2    Welch, M.J.3    Lee, A.M.4    Campbell, K.P.5    De La Torre, J.C.6    Oldstone, M.B.7
  • 43
    • 68249152608 scopus 로고    scopus 로고
    • Cell-intrinsic transforming growth factor-beta signaling mediates virus-specific CD8+ T cell deletion and viral persistence in vivo
    • R. Tinoco, V. Alcalde, Y. Yang, K. Sauer, and E.I. Zuniga Cell-intrinsic transforming growth factor-beta signaling mediates virus-specific CD8+ T cell deletion and viral persistence in vivo Immunity 31 2009 145 157
    • (2009) Immunity , vol.31 , pp. 145-157
    • Tinoco, R.1    Alcalde, V.2    Yang, Y.3    Sauer, K.4    Zuniga, E.I.5
  • 44
    • 0028844073 scopus 로고
    • An essential role for type 1 interferon-gamma in terminating persistent viral infection
    • A. Tishon, H. Lewicki, G. Rall, M. Von Herrath, and M.B. Oldstone An essential role for type 1 interferon-gamma in terminating persistent viral infection Virology 212 1995 244 250
    • (1995) Virology , vol.212 , pp. 244-250
    • Tishon, A.1    Lewicki, H.2    Rall, G.3    Von Herrath, M.4    Oldstone, M.B.5
  • 45
    • 33645025137 scopus 로고    scopus 로고
    • CD4 T cell control primary measles virus infection of the CNS: Regulation is dependent on combined activity with either CD8 T cells or with B cells: CD4, CD8 or B cells alone are ineffective
    • A. Tishon, H. Lewicki, A. Andaya, D. McGavern, L. Martin, and M.B. Oldstone CD4 T cell control primary measles virus infection of the CNS: regulation is dependent on combined activity with either CD8 T cells or with B cells: CD4, CD8 or B cells alone are ineffective Virology 347 2006 234 245
    • (2006) Virology , vol.347 , pp. 234-245
    • Tishon, A.1    Lewicki, H.2    Andaya, A.3    McGavern, D.4    Martin, L.5    Oldstone, M.B.6
  • 46
    • 60149109538 scopus 로고    scopus 로고
    • Toll-like receptor 7 mitigates lethal West Nile encephalitis via interleukin 23-dependent immune cell infiltration and homing
    • T. Town, F. Bai, T. Wang, A.T. Kaplan, F. Qian, R.R. Montgomery, J.F. Anderson, R.A. Flavell, and E. Fikrig Toll-like receptor 7 mitigates lethal West Nile encephalitis via interleukin 23-dependent immune cell infiltration and homing Immunity 30 2009 242 253
    • (2009) Immunity , vol.30 , pp. 242-253
    • Town, T.1    Bai, F.2    Wang, T.3    Kaplan, A.T.4    Qian, F.5    Montgomery, R.R.6    Anderson, J.F.7    Flavell, R.A.8    Fikrig, E.9
  • 47
    • 33750691709 scopus 로고    scopus 로고
    • PD-1 expression in acute hepatitis C virus (HCV) infection is associated with HCV-specific CD8 exhaustion
    • DOI 10.1128/JVI.01177-06
    • S. Urbani, B. Amadei, D. Tola, M. Massari, S. Schivazappa, G. Missale, and C. Ferrari PD-1 expression in acute hepatitis C virus (HCV) infection is associated with HCV-specific CD8 exhaustion J. Virol. 80 2006 11398 11403 (Pubitemid 44706581)
    • (2006) Journal of Virology , vol.80 , Issue.22 , pp. 11398-11403
    • Urbani, S.1    Amadei, B.2    Tola, D.3    Massari, M.4    Schivazappa, S.5    Missale, G.6    Ferrari, C.7
  • 48
    • 0029077692 scopus 로고
    • Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors
    • M.F. van den Broek, U. Müller, S. Huang, M. Aguet, and R.M. Zinkernagel Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors J. Virol. 69 1995 4792 4796
    • (1995) J. Virol. , vol.69 , pp. 4792-4796
    • Van Den Broek, M.F.1    Müller, U.2    Huang, S.3    Aguet, M.4    Zinkernagel, R.M.5
  • 49
    • 84862294199 scopus 로고    scopus 로고
    • Timing and magnitude of type i interferon responses by distinct viral sensors impact CD8 T cell exhaustion and chronic infection
    • this issue
    • Y. Wang, M. Sewiecki, M. Cella, G. Alber, R.D. Schreiber, G. Gilfillan, and M. Colonna Timing and magnitude of type I interferon responses by distinct viral sensors impact CD8 T cell exhaustion and chronic infection Cell Host Microbe 11 2012 631 642 this issue
    • (2012) Cell Host Microbe , vol.11 , pp. 631-642
    • Wang, Y.1    Sewiecki, M.2    Cella, M.3    Alber, G.4    Schreiber, R.D.5    Gilfillan, G.6    Colonna, M.7
  • 52
    • 67349201065 scopus 로고    scopus 로고
    • Hepatitis C virus single-stranded RNA induces innate immunity via Toll-like receptor 7
    • Y.L. Zhang, Y.J. Guo, Bin Li, and S.H. Sun Hepatitis C virus single-stranded RNA induces innate immunity via Toll-like receptor 7 J. Hepatol. 51 2009 29 38
    • (2009) J. Hepatol. , vol.51 , pp. 29-38
    • Zhang, Y.L.1    Guo, Y.J.2    Li, B.3    Sun, S.H.4


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