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Volumn 25, Issue 12, 2009, Pages 1287-1295

Increased expression of TLR7 in CD8+ T cells leads to TLR7-mediated activation and accessory cell-dependent IFN-γ production in HIV type 1 infection

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8;

EID: 73149111309     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.2008.0303     Document Type: Article
Times cited : (24)

References (46)
  • 1
    • 0028337166 scopus 로고
    • Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
    • Koup RA, Safrit JT, Cao Y, et al.: Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J Virol. 1994;68(7):4650-4655.
    • (1994) J Virol , vol.68 , Issue.7 , pp. 4650-4655
    • Koup, R.A.1    Safrit, J.T.2    Cao, Y.3
  • 2
    • 0023239322 scopus 로고
    • HIV-specific cytotoxic T lymphocytes in seropositive individuals
    • Walker BD, Chakrabarti S, Moss B, et al.: HIV-specific cytotoxic T lymphocytes in seropositive individuals. Nature 1987;328(6128):345-348.
    • (1987) Nature , vol.328 , Issue.6128 , pp. 345-348
    • Walker, B.D.1    Chakrabarti, S.2    Moss, B.3
  • 4
    • 0025843569 scopus 로고
    • Detection of cytotoxic T lymphocytes specific for synthetic peptides of gp160 in HIV-seropositive individuals
    • Clerici M, Lucey DR, Zajac RA, et al.: Detection of cytotoxic T lymphocytes specific for synthetic peptides of gp160 in HIV-seropositive individuals. J Immunol 1991;146(7):2214-2219.
    • (1991) J Immunol , vol.146 , Issue.7 , pp. 2214-2219
    • Clerici, M.1    Lucey, D.R.2    Zajac, R.A.3
  • 5
    • 0027403718 scopus 로고
    • Quantitative analysis of the human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T lymphocyte (CTL) response at different stages of HIV-1 infection: Differential CTL responses to HIV-1 and Epstein-Barr virus in late disease
    • Carmichael A, Jin X, Sissons P, and Borysiewicz L: Quantitative analysis of the human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T lymphocyte (CTL) response at different stages of HIV-1 infection: Differential CTL responses to HIV-1 and Epstein-Barr virus in late disease. J Exp Med 1993;177(2):249-256.
    • (1993) J Exp Med , vol.177 , Issue.2 , pp. 249-256
    • Carmichael, A.1    Jin, X.2    Sissons, P.3    Borysiewicz, L.4
  • 6
    • 0032846215 scopus 로고    scopus 로고
    • Longitudinal phenotypic analysis of human immunodeficiency virus type 1- specific cytotoxic T lymphocytes: Correlation with disease progression
    • Ogg GS, Kostense S, Klein MR, et al.: Longitudinal phenotypic analysis of human immunodeficiency virus type 1- specific cytotoxic T lymphocytes: Correlation with disease progression. J Virol 1999;73(11):9153-9160.
    • (1999) J Virol , vol.73 , Issue.11 , pp. 9153-9160
    • Ogg, G.S.1    Kostense, S.2    Klein, M.R.3
  • 7
    • 0032482177 scopus 로고    scopus 로고
    • Direct visualization of antigen-specific CD8+ T cells during the primary immune response to Epstein-Barr virus in vivo
    • Callan MF, Tan L, Annels N, et al.: Direct visualization of antigen-specific CD8+ T cells during the primary immune response to Epstein-Barr virus In vivo. J Exp Med 1998; 187(9):1395-1402.
    • (1998) J Exp Med , vol.187 , Issue.9 , pp. 1395-1402
    • Callan, M.F.1    Tan, L.2    Annels, N.3
  • 8
    • 0033511580 scopus 로고    scopus 로고
    • Cytomegalovirus (CMV)-specific T cell immunity after renal transplantation mediates protection from CMV disease by limiting the systemic virus load
    • Reusser P, Cathomas G, Attenhofer R, Tamm M, and Thiel G: Cytomegalovirus (CMV)-specific T cell immunity after renal transplantation mediates protection from CMV disease by limiting the systemic virus load. J Infect Dis 1999; 180(2):247-253.
    • (1999) J Infect Dis , vol.180 , Issue.2 , pp. 247-253
    • Reusser, P.1    Cathomas, G.2    Attenhofer, R.3    Tamm, M.4    Thiel, G.5
  • 9
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: Critical proteins linking innate and acquired immunity
    • DOI 10.1038/90609
    • Akira S, Takeda K, and Kaisho T: Toll-like receptors: Critical proteins linking innate and acquired immunity. Nat Immunol 2001;2(8):675-680. (Pubitemid 32747155)
    • (2001) Nature Immunology , vol.2 , Issue.8 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 10
    • 0036219195 scopus 로고    scopus 로고
    • CpG motifs in bacterial DNA and their immune effects
    • Krieg AM: CpG motifs in bacterial DNA and their immune effects. Annu Rev Immunol 2002;20:709-760.
    • (2002) Annu Rev Immunol , vol.20 , pp. 709-760
    • Krieg, A.M.1
  • 11
    • 33947668943 scopus 로고    scopus 로고
    • Viral recognition by Toll-like receptors
    • Barton GM: Viral recognition by Toll-like receptors. Semin Immunol 2007;19(1):33-40.
    • (2007) Semin Immunol , vol.19 , Issue.1 , pp. 33-40
    • Barton, G.M.1
  • 12
    • 44349166866 scopus 로고    scopus 로고
    • Anti-HIV activity mediated by natural killer and CD8+ cells after Toll-like receptor 7/8 triggering
    • Schlaepfer E and Speck RF: Anti-HIV activity mediated by natural killer and CD8+ cells after Toll-like receptor 7/8 triggering. PLoS One 2008;3(4):e1999.
    • (2008) PLoS One , vol.3 , Issue.4
    • Schlaepfer, E.1    Speck, R.F.2
  • 13
    • 27644513772 scopus 로고    scopus 로고
    • Endocytosis of HIV-1 activates plasmacytoid dendritic cells via Toll-like receptor-viral RNA interactions
    • Beignon AS, McKenna K, Skoberne M, et al.: Endocytosis of HIV-1 activates plasmacytoid dendritic cells via Toll-like receptor-viral RNA interactions. J Clin Invest 2005;115(11): 3265-3275.
    • (2005) J Clin Invest , vol.115 , Issue.11 , pp. 3265-3275
    • Beignon, A.S.1    McKenna, K.2    Skoberne, M.3
  • 14
    • 16644377329 scopus 로고    scopus 로고
    • Pleiotropic function of Toll-like receptors
    • Kaisho T and Akira S: Pleiotropic function of Toll-like receptors. Microbes Infect 2004;6(15):1388-1394.
    • (2004) Microbes Infect , vol.6 , Issue.15 , pp. 1388-1394
    • Kaisho, T.1    Akira, S.2
  • 15
    • 23844509234 scopus 로고    scopus 로고
    • Activation of human NK cells by plasmacytoid dendritic cells and its modulation by CD4+ T helper cells and CD4+ CD25hi T regulatory cells
    • Romagnani C, Della Chiesa M, Kohler S, et al.: Activation of human NK cells by plasmacytoid dendritic cells and its modulation by CD4+ T helper cells and CD4+ CD25hi T regulatory cells. Eur J Immunol 2005;35(8):2452-2458.
    • (2005) Eur J Immunol , vol.35 , Issue.8 , pp. 2452-2458
    • Romagnani, C.1    Della Chiesa, M.2    Kohler, S.3
  • 16
    • 0038781697 scopus 로고    scopus 로고
    • Regulation of dendritic cell function through toll-like receptors
    • DOI 10.2174/1566524033479366
    • Kaisho T and Akira S: Regulation of dendritic cell function through Toll-like receptors. Curr Mol Med 2003;3(8):759-771. (Pubitemid 37536880)
    • (2003) Current Molecular Medicine , vol.3 , Issue.8 , pp. 759-771
    • Kaisho, T.1    Akira, S.2
  • 18
    • 33747201640 scopus 로고    scopus 로고
    • Unique efficacy of Toll-like receptor 8 agonists in activating human neonatal antigen-Presenting cells
    • Levy O, Suter EE, Miller RL, and Wessels MR: Unique efficacy of Toll-like receptor 8 agonists in activating human neonatal antigen-presenting cells. Blood. 2006;108(4):1284-1290.
    • (2006) Blood , vol.108 , Issue.4 , pp. 1284-1290
    • Levy, O.1    Suter, E.E.2    Miller, R.L.3    Wessels, M.R.4
  • 19
    • 33845532053 scopus 로고    scopus 로고
    • Microbial translocation is a cause of systemic immune activation in chronic HIV infection
    • Brenchley JM, Price DA, Schacker TW, et al.: Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat Med 2006;12(12):1365-1371.
    • (2006) Nat Med , vol.12 , Issue.12 , pp. 1365-1371
    • Brenchley, J.M.1    Price, D.A.2    Schacker, T.W.3
  • 20
    • 27844541797 scopus 로고    scopus 로고
    • Control of B-cell responses by Toll-like receptors
    • Pasare C and Medzhitov R: Control of B-cell responses by Toll-like receptors. Nature 2005;438(7066):364-368.
    • (2005) Nature , vol.438 , Issue.7066 , pp. 364-368
    • Pasare, C.1    Medzhitov, R.2
  • 21
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001;25(4):402-408.
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 22
    • 1542297739 scopus 로고    scopus 로고
    • TLR2 is expressed on activated T cells as a costimulatory receptor
    • Komai-Koma M, Jones L, Ogg GS, Xu D, and Liew FY: TLR2 is expressed on activated T cells as a costimulatory receptor. Proc Natl Acad Sci USA 2004;101(9):3029-3034.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.9 , pp. 3029-3034
    • Komai-Koma, M.1    Jones, L.2    Ogg, G.S.3    Xu, D.4    Liew, F.Y.5
  • 23
    • 32444432610 scopus 로고    scopus 로고
    • Toll-like receptor 2 controls expansion and function of regulatory T cells
    • Sutmuller RP, den Brok MH, Kramer M, et al.: Toll-like receptor 2 controls expansion and function of regulatory T cells. J Clin Invest 2006;116(2):485-494.
    • (2006) J Clin Invest , vol.116 , Issue.2 , pp. 485-494
    • Sutmuller, R.P.1    Den Brok, M.H.2    Kramer, M.3
  • 24
    • 31144458579 scopus 로고    scopus 로고
    • Direct costimulatory effect of TLR3 ligand poly(I:C) on human gamma delta T lymphocytes
    • Wesch D, Beetz S, Oberg HH, Marget M, Krengel K, and Kabelitz D: Direct costimulatory effect of TLR3 ligand poly(I:C) on human gamma delta T lymphocytes. J Immunol. 2006;176(3):1348-1354.
    • (2006) J Immunol , vol.176 , Issue.3 , pp. 1348-1354
    • Wesch, D.1    Beetz, S.2    Oberg, H.H.3    Marget, M.4    Krengel, K.5    Kabelitz, D.6
  • 25
    • 29144534608 scopus 로고    scopus 로고
    • Human CD4+ T cells express TLR5 and its ligand flagellin enhances the suppressive capacity and expression of FOXP3 in CD4+CD25+ T regulatory cells
    • Crellin NK, Garcia RV, Hadisfar O, Allan SE, Steiner TS, and Levings MK: Human CD4+ T cells express TLR5 and its ligand flagellin enhances the suppressive capacity and expression of FOXP3 in CD4+CD25+ T regulatory cells. J Immunol 2005;175(12):8051-8059.
    • (2005) J Immunol , vol.175 , Issue.12 , pp. 8051-8059
    • Crellin, N.K.1    Garcia, R.V.2    Hadisfar, O.3    Allan, S.E.4    Steiner, T.S.5    Levings, M.K.6
  • 26
    • 33947204489 scopus 로고    scopus 로고
    • TLR ligands act directly upon T cells to restore proliferation in the absence of protein kinase C-theta signaling and promote autoimmune myocarditis
    • Marsland BJ, Nembrini C, Grun K, et al.: TLR ligands act directly upon T cells to restore proliferation in the absence of protein kinase C-theta signaling and promote autoimmune myocarditis. J Immunol 2007;178(6):3466-3473.
    • (2007) J Immunol , vol.178 , Issue.6 , pp. 3466-3473
    • Marsland, B.J.1    Nembrini, C.2    Grun, K.3
  • 27
    • 0037450804 scopus 로고    scopus 로고
    • Regulatory T cells selectively express Toll-like receptors and are activated by lipopolysaccharide
    • Caramalho I, Lopes-Carvalho T, Ostler D, Zelenay S, Haury M, and Demengeot J: Regulatory T cells selectively express Toll-like receptors and are activated by lipopolysaccharide. J Exp Med 2003;197(4):403-411.
    • (2003) J Exp Med , vol.197 , Issue.4 , pp. 403-411
    • Caramalho, I.1    Lopes-Carvalho, T.2    Ostler, D.3    Zelenay, S.4    Haury, M.5    Demengeot, J.6
  • 28
    • 0037080024 scopus 로고    scopus 로고
    • Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines
    • Zarember KA and Godowski PJ: Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines. J Immunol 2002;168(2):554-561.
    • (2002) J Immunol , vol.168 , Issue.2 , pp. 554-561
    • Zarember, K.A.1    Godowski, P.J.2
  • 29
    • 0036570169 scopus 로고    scopus 로고
    • Quantitative expression of Toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
    • Hornung V, Rothenfusser S, Britsch S, et al.: Quantitative expression of Toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J Immunol 2002; 168(9):4531-4537.
    • (2002) J Immunol , vol.168 , Issue.9 , pp. 4531-4537
    • Hornung, V.1    Rothenfusser, S.2    Britsch, S.3
  • 30
    • 41349107635 scopus 로고    scopus 로고
    • Toll-like receptor expression and responsiveness are increased in viraemic HIV-1 infection
    • Lester RT, Yao XD, Ball TB, et al.: Toll-like receptor expression and responsiveness are increased in viraemic HIV-1 infection. AIDS 2008;22(6):685-694.
    • (2008) AIDS , vol.22 , Issue.6 , pp. 685-694
    • Lester, R.T.1    Yao, X.D.2    Ball, T.B.3
  • 31
    • 34547403540 scopus 로고    scopus 로고
    • Predictors of disease progression in HIV infection: A review
    • Langford SE, Ananworanich J, and Cooper DA: Predictors of disease progression in HIV infection: A review. AIDS Res Ther 2007;4:11.
    • (2007) AIDS Res Ther , vol.4 , pp. 11
    • Langford, S.E.1    Ananworanich, J.2    Cooper, D.A.3
  • 32
    • 0037343278 scopus 로고    scopus 로고
    • Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia
    • Silvestri G, Sodora DL, Koup RA, et al.: Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia. Immunity 2003;18(3):441-452.
    • (2003) Immunity , vol.18 , Issue.3 , pp. 441-452
    • Silvestri, G.1    Sodora, D.L.2    Koup, R.A.3
  • 33
    • 0030987288 scopus 로고    scopus 로고
    • CCR5 levels and expression pattern correlate with infectability by macrophagetropic HIV-1, in vitro
    • Wu L, Paxton WA, Kassam N, et al.: CCR5 levels and expression pattern correlate with infectability by macrophagetropic HIV-1, in vitro. J Exp Med 1997;185(9):1681-1691.
    • (1997) J Exp Med , vol.185 , Issue.9 , pp. 1681-1691
    • Wu, L.1    Paxton, W.A.2    Kassam, N.3
  • 34
    • 0026764920 scopus 로고
    • NF-kappa B subunit regulation in nontransformed CD4+ T lymphocytes
    • Kang SM, Tran AC, Grilli M, and Lenardo MJ: NF-kappa B subunit regulation in nontransformed CD4+ T lymphocytes. Science 1992;256(5062):1452-1456.
    • (1992) Science , vol.256 , Issue.5062 , pp. 1452-1456
    • Kang, S.M.1    Tran, A.C.2    Grilli, M.3    Lenardo, M.J.4
  • 35
    • 0030055293 scopus 로고    scopus 로고
    • Engagement of adhesion molecules (CD18, CD11a, CD45, CD44, and CD58) enhances human immunodeficiency virus type 1 replication in monocytic cells through a tumor necrosis factor-modulated pathway
    • Shattock RJ, Rizzardi GP, Hayes P, and Griffin GE: Engagement of adhesion molecules (CD18, CD11a, CD45, CD44, and CD58) enhances human immunodeficiency virus type 1 replication in monocytic cells through a tumor necrosis factor-modulated pathway. J Infect Dis 1996;174(1): 54-62.
    • (1996) J Infect Dis , vol.174 , Issue.1 , pp. 54-62
    • Shattock, R.J.1    Rizzardi, G.P.2    Hayes, P.3    Griffin, G.E.4
  • 36
    • 0032845027 scopus 로고    scopus 로고
    • HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages
    • Swingler S, Mann A, Jacque J, et al.: HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages. Nat Med 1999;5(9):997-1103
    • (1999) Nat Med , vol.5 , Issue.9 , pp. 997-1103
    • Swingler, S.1    Mann, A.2    Jacque, J.3
  • 37
    • 0037047156 scopus 로고    scopus 로고
    • HIV envelope induces a cascade of cell signals in non-proliferating target cells that favor virus replication
    • Cicala C, Arthos J, Selig SM, et al.: HIV envelope induces a cascade of cell signals in non-proliferating target cells that favor virus replication. Proc Natl Acad Sci USA 2002; 99(14):9380-9385.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.14 , pp. 9380-9385
    • Cicala, C.1    Arthos, J.2    Selig, S.M.3
  • 38
    • 15444363618 scopus 로고    scopus 로고
    • Depletion of regulatory T cells in HIV infection is associated with immune activation
    • Eggena MP, Barugahare B, Jones N, et al.: Depletion of regulatory T cells in HIV infection is associated with immune activation. J Immunol 2005;174(7):4407-4414.
    • (2005) J Immunol , vol.174 , Issue.7 , pp. 4407-4414
    • Eggena, M.P.1    Barugahare, B.2    Jones, N.3
  • 39
    • 3242790766 scopus 로고    scopus 로고
    • Increased expression of Toll-like receptor 2 on monocytes in HIV infection: Possible roles in inflammation and viral replication
    • Heggelund L, Muller F, Lien E, et al.: Increased expression of Toll-like receptor 2 on monocytes in HIV infection: Possible roles in inflammation and viral replication. Clin Infect Dis 2004;39(2):264-269.
    • (2004) Clin Infect Dis , vol.39 , Issue.2 , pp. 264-269
    • Heggelund, L.1    Muller, F.2    Lien, E.3
  • 40
    • 26844577143 scopus 로고    scopus 로고
    • Increased expression of TLR3 in lymph nodes during simian immunodeficiency virus infection: Implications for inflammation and immunodeficiency
    • Sanghavi SK and Reinhart TA: Increased expression of TLR3 in lymph nodes during simian immunodeficiency virus infection: Implications for inflammation and immunodeficiency. J Immunol 2005;175(8):5314-5323.
    • (2005) J Immunol , vol.175 , Issue.8 , pp. 5314-5323
    • Sanghavi, S.K.1    Reinhart, T.A.2
  • 41
    • 45949106077 scopus 로고    scopus 로고
    • Toll-like receptor 2 acts as a natural innate immune receptor to clear amyloid beta 1-42 and delay the cognitive decline in a mouse model of Alzheimer's disease
    • Richard KL, Filali M, Prefontaine P, and Rivest S: Toll-like receptor 2 acts as a natural innate immune receptor to clear amyloid beta 1-42 and delay the cognitive decline in a mouse model of Alzheimer's disease. J Neurosci 2008;28(22):5784-5793.
    • (2008) J Neurosci , vol.28 , Issue.22 , pp. 5784-5793
    • Richard, K.L.1    Filali, M.2    Prefontaine, P.3    Rivest, S.4
  • 42
    • 45949083609 scopus 로고    scopus 로고
    • TLR2 signaling renders quiescent naive and memory CD4+ T cells more susceptible to productive infection with X4 and R5 HIV-type 1
    • Thibault S, Tardif MR, Barat C, and Tremblay MJ: TLR2 signaling renders quiescent naive and memory CD4+ T cells more susceptible to productive infection with X4 and R5 HIV-type 1. J Immunol 2007;179(7):4357-4366.
    • (2007) J Immunol , vol.179 , Issue.7 , pp. 4357-4366
    • Thibault, S.1    Tardif, M.R.2    Barat, C.3    Tremblay, M.J.4
  • 43
    • 44849137950 scopus 로고    scopus 로고
    • Toll-like receptor ligands induce human T cell activation and death, a model for HIV pathogenesis
    • Funderburg N, Luciano AA, Jiang W, Rodriguez B, Sieg SF, and Lederman MM: Toll-like receptor ligands induce human T cell activation and death, a model for HIV pathogenesis. PLoS One 2008;3(4):e1915.
    • (2008) PLoS One , vol.3 , Issue.4
    • Funderburg, N.1    Luciano, A.A.2    Jiang, W.3    Rodriguez, B.4    Sieg, S.F.5    Lederman, M.M.6
  • 44
    • 34547130280 scopus 로고    scopus 로고
    • MyD88-dependent immune activation mediated by human immunodeficiency virus type 1-encoded Toll-like receptor ligands
    • Meier A, Alter G, Frahm N, et al.: MyD88-dependent immune activation mediated by human immunodeficiency virus type 1-encoded Toll-like receptor ligands. J Virol 2007; 81(15):8180-8191.
    • (2007) J Virol , vol.81 , Issue.15 , pp. 8180-8191
    • Meier, A.1    Alter, G.2    Frahm, N.3
  • 45
    • 22544450733 scopus 로고    scopus 로고
    • Direct stimulation of human T cells via TLR5 and TLR7/8: Flagellin and R-848 up-regulate proliferation and IFN-gamma production by memory CD4+ T cells
    • Caron G, Duluc D, Fremaux I, et al.: Direct stimulation of human T cells via TLR5 and TLR7/8: Flagellin and R-848 up-regulate proliferation and IFN-gamma production by memory CD4+ T cells. J Immunol 2005;175(3):1551-1557.
    • (2005) J Immunol , vol.175 , Issue.3 , pp. 1551-1557
    • Caron, G.1    Duluc, D.2    Fremaux, I.3


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