Key considerations for optimization of formulation and melt-extrusion process parameters for developing thermosensitive compound

Pharmaceutical Development and Technology

Volumn 17, Issue 4, 2012, Pages 502-510

  Ghosh, Indrajit ^a   Vippagunta, Radha ^a   Li, Shoufeng ^a   Vippagunta, Sudha ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Extrusion temperature; Glass transition temperature; Melt extrusion; Thermosensitive compound; Twin screw extruder

Indexed keywords

ARTICLE; DEGRADATION; FLOW MEASUREMENT; HEAT SENSITIVITY; HEAT STRESS; MELT EXTRUSION PROCESS; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROCESS TECHNOLOGY; TABLET HARDNESS; TABLET PROPERTY;

CHEMISTRY, PHARMACEUTICAL; DRUG COMPOUNDING; DRUG STABILITY; HARDNESS; PHARMACEUTICAL PREPARATIONS; PHASE TRANSITION; POWDER DIFFRACTION; TABLETS; TRANSITION TEMPERATURE; X-RAY DIFFRACTION;

EID: 84862285564     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.3109/10837450.2010.550624     Document Type: Article

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