Applications of hot-melt extrusion for drug delivery

Expert Opinion on Drug Delivery

Volumn 5, Issue 12, 2008, Pages 1357-1376

  Repka, Michael A ^a,b   Majumdar, Soumyajit ^a,b   Battu, Sunil Kumar ^a   Srirangam, Ramesh ^a   Upadhye, Sampada B ^a  

^a UNIVERSITY OF MISSISSIPPI   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Bioadhesion; Bioavailability; Controlled release; Drug delivery system; Hot melt extrusion; Melt extruded films; Melt extruded tablets; Solid dispersion; Sustained release

Indexed keywords

ACETOHYDROXAMIC ACID; BETA CYCLODEXTRIN SULFOBUTYL ETHER; CARBOMER; CHLORPHENIRAMINE MALEATE; CLOTRIMAZOLE; DICLOFENAC; DILTIAZEM; ESTRADIOL; EUDRAGIT; GELUCIRE; GUAIFENESIN; HYDRALAZINE; HYDROXYPROPYLMETHYLCELLULOSE; IBUPROFEN; ITRACONAZOLE; KETOCONAZOLE; KETOPROFEN; LIDOCAINE; MACROGOL 400; MACROGOL 6000; MANNITOL; MESALAZINE; NIMODIPINE; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL; PHTHALIC ACID DIETHYL ESTER; POVIDONE; THEOPHYLLINE; UNINDEXED DRUG; VAPREOTIDE;

AREA UNDER THE CURVE; AUTOMATION; CLINICAL TRIAL; CONTROLLED RELEASE FORMULATION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CAPSULE; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG GRANULE; DRUG IMPLANT; DRUG MANUFACTURE; DRUG MIXTURE; DRUG PELLET; DRUG SOLUBILITY; ENTERIC COATED TABLET; FILM; HUMAN; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PELLET EXTRUSION; REVIEW; SUSTAINED DRUG RELEASE; SUSTAINED RELEASE FORMULATION; TABLET COMPRESSION; TABLET FORMULATION; TIME TO MAXIMUM PLASMA CONCENTRATION; VAGINA RING;

BIOLOGICAL AVAILABILITY; CHEMISTRY, PHYSICAL; DELAYED-ACTION PREPARATIONS; DRUG ADMINISTRATION ROUTES; DRUG CARRIERS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; HOT TEMPERATURE; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL;

EID: 58149195305     PISSN: 17425247     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425240802583421     Document Type: Review

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