Distribution of urocortins and corticotropin-releasing factor receptors in the cardiovascular system

International Journal of Endocrinology

Volumn 2012, Issue , 2012, Pages

  Takahashi, Kazuhiro ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN RELEASING FACTOR RECEPTOR; CORTICOTROPIN RELEASING FACTOR RECEPTOR 2; CORTICOTROPIN RELEASING FACTOR RECEPTOR 2 ALPHA; CORTICOTROPIN RELEASING FACTOR RECEPTOR 2 BETA; UNCLASSIFIED DRUG; UROCORTIN I; UROCORTIN II; UROCORTIN III;

CARDIOVASCULAR SYSTEM; DRUG EFFECT; HEART FAILURE; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HUMAN; HYPERTENSION; IMMUNOREACTIVITY; INOTROPISM; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REPERFUSION INJURY; REVIEW; VASODILATATION;

EID: 84862272288     PISSN: 16878337     EISSN: 16878345     Source Type: Journal    
DOI: 10.1155/2012/395284     Document Type: Review

References (91)

1. Chen R., Lewis K. A., Perrin M. H., Vale W. W., Expression cloning of a human corticotropin-releasing-factor receptor Proceedings of the National Academy of Sciences of the United States of America 1993 90 19 8967 8971 (Pubitemid 23306432)
2. Lovenberg T. W., Liaw C. W., Grigoriadis D. E., Clevenger W., Chalmers D. T., De Souza E. B., Oltersdorf T., Cloning and characterization of a functionally distinct corticotropin-releasing factor receptor subtype from rat brain Proceedings of the National Academy of Sciences of the United States of America 1995 92 3 836 840
3. Weninger S. C., Dunn A. J., Muglia L. J., Dikkes P., Miczek K. A., Swiergiel A. H., Berridge C. W., Majzoub J. A., Stress-induced behaviors require the corticotropin-releasing hormone (CRH) receptor, but not CRH Proceedings of the National Academy of Sciences of the United States of America 1999 96 14 8283 8288 (Pubitemid 29328446)
4. Smith G. W., Aubry J. M., Dellu F., Contarino A., Bilezikjian L. M., Gold L. H., Chen R., Marchuk Y., Hauser C., Bentley C. A., Sawchenko P. E., Koob G. F., Vale W., Lee K. F., Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development Neuron 1998 20 6 1093 1102 (Pubitemid 28293127)
5. Coste S. C., Kesterson R. A., Heldwein K. A., Stevens S. L., Heard A. D., Hollis J. H., Murray S. E., Hill J. K., Pantely G. A., Hohimer A. R., Hatton D. C., Phillips T. J., Finn D. A., Low M. J., Rittenberg M. B., Stenzel P., Stenzel-Poore M. P., Abnormal adaptations to stress and impaired cardiovascular function in mice lacking corticotropin-releasing hormone receptor-2 Nature Genetics 2000 24 4 403 409 (Pubitemid 30187442)
6. Bale T. L., Contarino A., Smith G. W., Chan R., Gold L. H., Sawchenko P. E., Koob G. F., Vale W. W., Lee K. F., Mice deficient for corticotropin- releasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress Nature Genetics 2000 24 4 410 414 (Pubitemid 30187443)
7. Kishimoto T., Radulovic J., Radulovic M., Lin C. R., Schrick C., Hooshmand F., Hermanson O., Rosenfeld M. G., Spiess J., Deletion of Crhr2 reveals an anxiolytic role for corticotropin-releasing hormone receptor-2 Nature Genetics 2000 24 4 415 419 (Pubitemid 30187444)
8. Stenzel P., Kesterson R., Yeung W., Cone R. D., Rittenberg M. B., Stenzel-Poore M. P., Identification of a novel murine receptor for corticotropin-releasing hormone expressed in the heart Molecular Endocrinology 1995 9 5 637 645
9. Perrin M., Donaldson C., Chen R., Blount A., Berggren T., Bilezikjian L., Sawchenko P., Vale W., Identification of a second corticotropin-releasing factor receptor gene and characterization of a cDNA expressed in heart Proceedings of the National Academy of Sciences of the United States of America 1995 92 7 2969 2973
10. Kishimoto T., Pearse R. V. II, Lin C. R., Rosenfeld M. G., A sauvagine/corticotropin-releasing factor receptor expressed in heart and skeletal muscle Proceedings of the National Academy of Sciences of the United States of America 1995 92 4 1108 1112
11. Lovenberg T. W., Chalmers D. T., Liu C., de Souza E. B., CRF2 and CRF2 receptor mRNAs are differentially distributed between the rat central nervous system and peripheral tissues Endocrinology 1995 136 9 4139 4142
12. Lederis K., Fryer J., Rivier J., MacCannell K. L., Kobayashi Y., Woo N., Wong K. L., Neurohormones from fish tails. II: actions of urotensin I in mammals and fishes Recent Progress in Hormone Research 1985 41 553 576
13. Bern H. A., Pearson D., Larson B. A., Nishioka R. S., Neurohormones from fish tails: the caudal neurosecretory system. I. Urophysiology and the caudal neurosecretory system of fishes Recent Progress in Hormone Research 1985 41 533 552
14. Vauhan J., Donaldson C., Bittencourt J., Perrin M. H., Lewis K., Sutton S., Chan R., Turnbull A. V., Lovejoy D., Rivier C., Rivier J., Sawchenko P. E., Vale W., Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor Nature 1995 378 6554 287 292
15. Reyes T. M., Lewis K., Perrin M. H., Kunitake K. S., Vaughan J., Arias C. A., Hogenesch J. B., Gulyas J., Rivier J., Vale W. W., Sawchenko P. E., Urocortin II: a member of the corticotropin-releasing factor (CRF) neuropeptide family that is selectively bound by type 2 CRF receptors Proceedings of the National Academy of Sciences of the United States of America 2001 98 5 2843 2848 (Pubitemid 32209571)
16. Lewis K., Li C., Perrin M. H., Blount A., Kunitake K., Donaldson C., Vaughan J., Reyes T. M., Gulyas J., Fischer W., Bilezikjian L., Rivier J., Sawchenko P. E., Vale W. W., Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor Proceedings of the National Academy of Sciences of the United States of America 2001 98 13 7570 7575 (Pubitemid 32567989)
17. Hsu S. Y., Hsueh A. J. W., Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor Nature Medicine 2001 7 5 605 611 (Pubitemid 32448329)
18. Takahashi K., Totsune K., Sone M., Murakami O., Satoh F., Arihara Z., Sasano H., Iino K., Mouri T., Regional distribution of urocortin-like immunoreactivity and expression of urocortin mRNA in the human brain Peptides 1998 19 4 643 647 (Pubitemid 28254999)
19. Iino K., Sasano H., Oki Y., Andoh N., Shin R. W., Kitamoto T., Totsune K., Takahashi K., Suzuki H., Nagura H., Yoshimi T., Urocortin expression in human pituitary gland and pituitary adenoma Journal of Clinical Endocrinology Metabolism 1997 82 11 3842 3850 (Pubitemid 27509381)
20. Iino K., Sasano H., Oki Y., Andoh N., Shin R. W., Kitamoto T., Takahashi K., Suzuki H., Tezuka F., Yoshimi T., Nagura H., Urocortin expression in the human central nervous system Clinical Endocrinology 1999 50 1 107 114 (Pubitemid 29079375)
21. Muramatsu Y., Fukushima K., Iino K., Totsune K., Takahashi K., Suzuki T., Hirasawa G., Takeyama J., Ito M., Nose M., Tashiro A., Hongo M., Oki Y., Nagura H., Sasano H., Urocortin and corticotropin-releasing factor receptor expression in the human colonic mucosa Peptides 2000 21 12 1799 1809 (Pubitemid 32058855)
22. Muramatsu Y., Sugino N., Suzuki T., Totsune K., Takahashi K., Tashiro A., Hongo M., Oki Y., Sasano H., Urocortin and corticotropin-releasing factor receptor expression in normal cycling human ovaries Journal of Clinical Endocrinology Metabolism 2001 86 3 1362 1369 (Pubitemid 32323029)
23. Petraglia F., Florio P., Gallo R., Simoncini T., Saviozzi M., di Blasio A. M., Vaughan J., Vale W., Human placenta and fetal membranes express human urocortin mRNA and peptide Journal of Clinical Endocrinology Metabolism 1996 81 10 3807 3810 (Pubitemid 26339958)
24. Uzuki M., Sasano H., Muramatsu Y., Totsune K., Takahashi K., Oki Y., Iino K., Sawai T., Urocortin in the synovial tissue of patients with rheumatoid arthritis Clinical Science 2001 100 6 577 589 (Pubitemid 32523309)
25. Bamberger C. M., Wald M., Bamberger A. M., Ergn S., Beil F. U., Schulte H. M., Human lymphocytes produce urocortin, but not corticotropin-releasing hormone Journal of Clinical Endocrinology Metabolism 1998 83 2 708 711 (Pubitemid 28496563)
26. Slominski A., Zbytek B., Zmijewski M., Slominski R. M., Kauser S., Wortsman J., Tobin D. J., Corticotropin releasing hormone and the skin Frontiers in Bioscience 2006 11 1 2230 2248 (Pubitemid 43832722)
27. Takahashi K., Totsune K., Murakami O., Shibahara S., Urocortins as cardiovascular peptides Peptides 2004 25 10 1723 1731 (Pubitemid 39346214)
28. Takahashi K., Translational medicine in fish-derived peptides: from fish endocrinology to human physiology and diseases Endocrine Journal 2004 51 1 1 17 (Pubitemid 38405139)
29. Kimura Y., Takahashi K., Totsune K., Muramatsu Y., Kaneko C., Darnel A. D., Suzuki T., Ebina M., Nukiwa T., Sasano H., Expression of urocortin and corticotropin-releasing factor receptor subtypes in the human heart Journal of Clinical Endocrinology Metabolism 2002 87 1 340 346 (Pubitemid 34084712)
30. Takahashi K., Totsune K., Murakami O., Saruta M., Nakabayashi M., Suzuki T., Sasano H., Shibahara S., Expression of urocortin III/stresscopin in human heart and kidney Journal of Clinical Endocrinology Metabolism 2004 89 4 1897 1903 (Pubitemid 38507951)
31. Nishikimi T., Miyata A., Horio T., Yoshihara F., Nagaya N., Takishita S., Yutani C., Matsuo H., Matsuoka H., Kangawa K., Urocortin, a member of the corticotropin-releasing factor family, in normal and diseased heart American Journal of Physiolog 2000 279 6 H3031 H3039
32. Kageyama K., Hanada K., Suda T., Differential regulation of urocortins1-3 mRNA in human umbilical vein endothelial cells Regulatory Peptides 2009 155 13 131 138
33. Clifton V. L., Gu Q., Murphy V. E., Schwartz J., Madsen G., Smith R., Localization and characterization of urocortin during human pregnancy Placenta 2000 21 8 782 788
34. Imperatore A., Florio P., Torres P. B., Torricelli M., Galleri L., Toti P., Occhini R., Picciolini E., Vale W., Petraglia F., Urocortin 2 and urocortin 3 are expressed by the human placenta, deciduas, and fetal membranes American Journal of Obstetrics and Gynecology 2006 195 1 288 295 (Pubitemid 43927516)
35. Watanabe F., Oki Y., Ozawa M., Masuzawa M., Iwabuchi M., Yoshimi T., Nishiguchi T., Iino K., Sasano H., Urocortin in human placenta and maternal plasma Peptides 1999 20 2 205 209 (Pubitemid 29332102)
36. Wiley K. E., Davenport A. P., CRF2 receptors are highly expressed in the human cardiovascular system and their cognate ligands urocortins 2 and 3 are potent vasodilators British Journal of Pharmacology 2004 143 4 508 514 (Pubitemid 39452218)
37. Dermitzaki E., Tsatsanis C., Minas V., Chatzaki E., Charalampopoulos I., Venihaki M., Androulidaki A., Lambropoulou M., Spiess J., Michalodimitrakis E., Gravanis A., Margioris A. N., Corticotropin-releasing factor (CRF) and the urocortins differentially regulate catecholamine secretion in human and rat adrenals, in a CRF receptor type-specific manner Endocrinology 2007 148 4 1524 1538 (Pubitemid 46457096)
38. Ikeda K., Tojo K., Tokudome G., Ohta M., Sugimoto K. I., Tamura T., Tajima N., Mochizuki S., Kawakami M., Hosoya T., Cardiac expression of urocortin (Ucn) in diseased heart; preliminary results on possible involvement of Ucn in pathophysiology of cardiac diseases Molecular and Cellular Biochemistry 2003 252 1-2 25 32 (Pubitemid 37220729)
39. Ng L. L., Loke I. W., O'Brien R. J., Squire I. B., Davies J. E., Plasma urocortin in human systolic heart failure Clinical Science 2004 106 4 383 388 (Pubitemid 38553586)
40. Wright S. P., Doughty R. N., Frampton C. M., Gamble G. D., Yandle T. G., Richards A. M., Plasma urocortin 1 in human heart failure Circulation 2009 2 5 465 471
41. Gruson D., Ahn S. A., Ketelslegers J. M., Rousseau M. F., Circulating levels of stress associated peptide Urocortin in heart failure patients Peptides 2010 31 2 354 356
42. Kageyama K., Gaudriault G. E., Bradbury M. J., Vale W. W., Regulation of corticotropin-releasing factor receptor type 2 messenger ribonucleic acid in the rat cardiovascular system by urocortin, glucocorticoids, and cytokines Endocrinology 2000 141 7 2285 2293 (Pubitemid 32269046)
43. Coste S. C., Heldwein K. A., Stevens S. L., Tobar-Dupres E., Stenzel-Poore M. P., IL-1 and TNF down-regulate CHR receptor-2 mRNA expression in the mouse heart Endocrinology 2001 142 8 3537 3545 (Pubitemid 32681762)
44. Fukuda T., Takahashi K., Suzuki T., Saruta M., Watanabe M., Nakata T., Sasano H., Urocortin 1, urocortin 3/stresscopin, and corticotropin-releasing factor receptors in human adrenal and its disorders Journal of Clinical Endocrinology Metabolism 2005 90 8 4671 4678 (Pubitemid 41159357)
45. Takahashi K., Totsune K., Saruta M., Fukuda T., Suzuki T., Hirose T., Imai Y., Sasano H., Murakami O., Expression of urocortin 3/stresscopin in human adrenal glands and adrenal tumors Peptides 2006 27 1 178 182 (Pubitemid 43061053)
46. Arihara Z., Sakurai K., Osaki Y., ACTH response to desmopressin in a patient with acromegaly; expression of corticotropin-releasing factor, urocortins and vasopressin V1b receptor in GH-producing pituitary adenoma Endocrine Journal 2011 58 12 1029 1036
47. Kageyama K., Sakihara S., Yamashita M., Takahashi K., Kawashima S., Tanabe J., Tsutaya S., Yasujima M., Suda T., A case of multiple endocrine neoplasia type II accompanied by thyroid medullary carcinoma and pheochromocytomas expressing corticotropin-releasing factor and urocortins American Journal of the Medical Sciences 2008 335 5 398 402
48. Saruta M., Takahashi K., Suzuki T., Torii A., Kawakami M., Sasano H., Urocortin 1 in colonic mucosa in patients with ulcerative colitis Journal of Clinical Endocrinology and Metabolism 2004 89 11 5352 5361 (Pubitemid 39518408)
49. Ikeda K., Tojo K., Inada Y., Takada Y., Sakamoto M., Lam M., Claycomb W. C., Tajima N., Regulation of urocortin I and its related peptide urocortin II by inflammatory and oxidative stresses in HL-1 cardiomyocytes Journal of Molecular Endocrinology 2009 42 6 479 489
50. Gullestad L., Aukrust P., Review of trials in chronic heart failure showing broad-spectrum anti-inflammatory approaches American Journal of Cardiology 2005 95 11 17C 23C (Pubitemid 40755514)
51. Okosi A., Brar B. K., Chan M., D'Souza L., Smith E., Stephanou A., Latchman D. S., Chowdrey H. S., Knight R. A., Expression and protective effects of urocortin in cardiac myocytes Neuropeptides 1998 32 2 167 171 (Pubitemid 28212540)
52. Yamashita K., Discher D. J., Hu J., Bishopric N. H., Webster K. A., Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, AND p300/CBP Journal of Biological Chemistry 2001 276 16 12645 12653
53. Nakayama M., Takahashi K., Murakami O., Shirato K., Shibahara S., Induction of adrenomedullin by hypoxia and cobalt chloride in human colorectal carcinoma cells Biochemical and Biophysical Research Communications 1998 243 2 514 517 (Pubitemid 28414056)
54. Garayoa M., Martnez A., Lee S., Po R., An W. G., Neckers L., Trepel J., Montuenga L. M., Ryan H., Johnson R., Gassmann M., Cuttitta F., Hypoxia-inducible factor-1 (HIF-1) up-regulates adrenomedullin expression in human tumor cell lines during oxygen deprivation: a possible promotion mechanism of carcinogenesis Molecular Endocrinology 2000 14 6 848 862 (Pubitemid 32260498)
55. Choy M. Y., Leung T. N., Leung P. S., Lau T. K., Effect of hypoxia on urocortin production in human gestational trophoblasts in vitro American Journal of Reproductive Immunology 2004 52 2 118 123 (Pubitemid 39149314)
56. Chanalaris A., Lawrence K. M., Stephanou A., Knight R. D., Hsu S. Y., Hsueh A. J. W., Latchman D. S., Protective effects of the urocortin homologues stresscopin (SCP) and stresscopin-related peptide (SRP) against hypoxia/reoxygenation injury in rat neonatal cardiomyocytes Journal of Molecular and Cellular Cardiology 2003 35 10 1295 1305 (Pubitemid 37163536)
57. Imperatore A., Rolfo A., Petraglia F., Challis J. R., Caniggia I., Hypoxia and preeclampsia: increased expression of urocortin 2 and urocortin 3 Reproductive Sciences 2010 17 9 833 843
58. Bhler K., Plaisance I., Dieterle T., Brin M., The human urocortin 2 gene is regulated by hypoxia: identification of a hypoxia-responsive element in the 3′-flanking region Biochemical Journal 2009 424 1 119 127
59. Saruta M., Takahashi K., Suzuki T., Fukuda T., Torii A., Sasano H., Urocortin 3/stresscopin in human colon: possible modulators of gastrointestinal function during stressful conditions Peptides 2005 26 7 1196 1206 (Pubitemid 40798076)
60. Leitch I. M., Boura A. L. A., Botti C., Read M. A., Walters W. A. W., Smith R., Vasodilator actions of urocortin and related peptides in the human perfused placenta in vitro Journal of Clinical Endocrinology Metabolism 1998 83 12 4510 4513 (Pubitemid 29100159)
61. Dieterle T., Meili-Butz S., Bhler K., Morandi C., John D., Buser P. T., Rivier J., Vale W. W., Peterson K. L., Brink M., Immediate and sustained blood pressure lowering by urocortin 2 a novel approach to antihypertensive therapy? Hypertension 2009 53 4 739 744
62. Rademaker M. T., Cameron V. A., Charles C. J., Richards A. M., Urocortin 3: haemodynamic, hormonal, and renal effects in experimental heart failure European Heart Journal 2006 27 17 2088 2098 (Pubitemid 44412817)
63. Brar B. K., Jonassen A. K., Stephanou A., Santilli G., Railson J., Knight R. A., Yellon D. M., Latchman D. S., Urocortin protects against ischemic and reperfusion injury via a MAPK-dependent pathway Journal of Biological Chemistry 2000 275 12 8508 8514 (Pubitemid 30180198)
64. Brar B. K., Jonassen A. K., Egorina E. M., Chen A., Negro A., Perrin M. H., Mjs O. D., Latchman D. S., Lee K. F., Vale W., Urocortin-II and urocortin-III are cardioprotective against ischemia reperfusion injury: an essential endogenous cardioprotective role for corticotropin releasing factor receptor type 2 in the murine heart Endocrinology 2004 145 1 24 35 (Pubitemid 38094496)
65. Scarabelli T. M., Pasini E., Stephanou A., Comini L., Curello S., Raddino R., Ferrari R., Knight R., Latchman D. S., Urocortin promotes hemodynamic and bioenergetic recovery and improves cell survival in the isolated rat heart exposed to ischemia/reperfusion Journal of the American College of Cardiology 2002 40 1 155 161 (Pubitemid 34701391)
66. Ikeda K., Tojo K., Oki Y., Nakao K., Urocortin has cell-proliferative effects on cardiac non-myocytes Life Sciences 2002 71 16 1929 1938 (Pubitemid 34880237)
67. Ikeda K., Tojo K., Otsubo C., Udagawa T., Hosoya T., Tajima N., Nakao K., Kawamura M., Effects of urocortin II on neonatal rat cardiac myocytes and non-myocytes Peptides 2005 26 12 2473 2481 (Pubitemid 41676719)
68. Lawrence K. M., Chanalaris A., Scarabelli T., Hubank M., Pasini E., Townsend P. A., Comini L., Ferrari R., Tinker A., Stephanou A., Knight R. A., Latchman D. S., KATP channel gene expression is induced by urocortin and mediates its cardioprotective effect Circulation 2002 106 12 1556 1562
69. Townsend P. A., Davidson S. M., Clarke S. J., Khaliulin I., Carroll C. J., Scarabelli T. M., Knight R. A., Stephanou A., Latchman D. S., Halestrap A. P., Urocortin prevents mitochondrial permeability transition in response to reperfusion injury indirectly by reducing oxidative stress American Journal of Physiology 2007 293 2 H928 H938
70. Barry S. P., Lawrence K. M., McCormick J., Soond S. M., Hubank M., Eaton S., Sivarajah A., Scarabelli T. M., Knight R. A., Thiemermann C., Latchman D. S., Townsend P. A., Stephanou A., New targets of urocortin-mediated cardioprotection Journal of Molecular Endocrinology 2010 45 2 69 85
71. Cserepes B., Jancs G., Gasz B., Rcz B., Ferenc A., Benk L., Borsiczky B., Krthy M., Ferencz S., Lantos J., Gl J., Arat E., Miseta A., Wéber G., Rth E., Cardioprotective action of urocortin in early pre-and postconditioning Annals of the New York Academy of Sciences 2007 1095 228 239 (Pubitemid 47092455)
72. Rademaker M. T., Charles C. J., Espiner E. A., Fisher S., Frampton C. M., Kirkpatrick C. M. J., Lainchbury J. G., Nicholls M. G., Richards A. M., Vale W. W., Beneficial hemodynamic, endocrine, and renal effects of urocortin in experimental heart failure: comparison with normal sheep Journal of the American College of Cardiology 2002 40 8 1495 1505 (Pubitemid 35192877)
73. Rademaker M. T., Cameron V. A., Charles C. J., Richards A. M., Integrated hemodynamic, hormonal, and renal actions of urocortin 2 in normal and paced sheep: beneficial effects in heart failure Circulation 2005 112 23 3624 3632 (Pubitemid 43739541)
74. Rademaker M. T., Charles C. J., Richards A. M., Urocortin 1 administration from onset of rapid left ventricular pacing represses progression to overt heart failure American Journal of Physiology 2007 293 3 H1536 H1544
75. Rademaker M. T., Charles C. J., Ellmers L. J., Lewis L. K., Nicholls M. G., Richards A. M., Prolonged urocortin 2 administration in experimental heart failure: sustained hemodynamic, endocrine, and renal effects Hypertension 2011 57 6 1136 1144
76. Charles C. J., Jardine D. L., Nicholls M. G., Rademaker M. T., Richards A. M., Urocortin 1 exhibits potent inhibition of cardiac sympathetic nerve activity in conscious sheep Journal of Hypertension 2008 26 1 53 60 (Pubitemid 350294849)
77. Rademaker M. T., Charles C. J., Nicholls M. G., Richards A. M., Urocortin 2 inhibits furosemide-induced activation of renin and enhances renal function and diuretic responsiveness in experimental heart failure Circulation 2009 2 6 532 540
78. Charles C. J., Jardine D. L., Rademaker M. T., Richards A. M., Urocortin 2 induces potent long-lasting inhibition of cardiac sympathetic drive despite baroreflex activation in conscious sheep Journal of Endocrinology 2010 204 2 181 189
79. Charles C. J., Jardine D. L., Rademaker M. T., Richards M., Urocortin 3 inhibits cardiac sympathetic nerve activity in conscious sheep Journal of Cardiovascular Pharmacology 2011 58 4 418 423
80. Davis M. E., Pemberton C. J., Yandle T. G., Fisher S. F., Lainchbury J. G., Frampton C. M., Rademaker M. T., Richards M., Urocortin 2 infusion in human heart failure European Heart Journal 2007 28 21 2589 2597 (Pubitemid 350071510)
81. Bale T. L., Hoshijima M., Gu Y., Dalton N., Anderson K. R., Lee K. F., Rivier J., Chien K. R., Vale W. W., Peterson K. L., The cardiovascular physiologic actions of urocortin II: acute effects in murine heart failure Proceedings of the National Academy of Sciences of the United States of America 2004 101 10 3697 3702 (Pubitemid 38338257)
82. Yang L. Z., Kockskmper J., Khan S., Suarez J., Walther S., Doleschal B., Unterer G., Khafaga M., McHler H., Heinzel F. R., Dillmann W. H., Pieske B., Spiess J., CAMP-and Ca 2+ /calmodulin-dependent protein kinases mediate inotropic, lusitropic and arrhythmogenic effects of urocortin 2 in mouse ventricular myocytes British Journal of Pharmacology 2011 162 2 544 556
83. Meili-Butz S., Bhler K., John D., Buser P., Vale W. W., Peterson K. L., Brink M., Dieterle T., Acute effects of urocortin 2 on cardiac function and propensity for arrhythmias in an animal model of hypertension-induced left ventricular hypertrophy and heart failure European Journal of Heart Failure 2010 12 8 797 804
84. Gu Y., Zhang K., Biswas N., Friese R. S., Lin D. H., Mahata S. K., Hoshijima M., O'Connor D. T., Peterson K. L., Brar B. K., Urocortin 2 lowers blood pressure and reduces plasma catecholamine levels in mice with hyperadrenergic activity Endocrinology 2010 151 10 4820 4829
85. Gray G. A., Webb D. J., The endothelin system and its potential as a therapeutic target in cardiovascular disease Pharmacology Therapeutics 1996 72 2 109 148 (Pubitemid 26423301)
86. Burnier M., Brunner H. R., Angiotensin II receptor antagonists The Lancet 2000 355 9204 637 645 (Pubitemid 30099477)
87. Takahashi K., Hirose T., Mori N., Morimoto R., Kohzuki M., Imai Y., Totsune K., The renin-angiotensin system, adrenomedullins and urotensin II in the kidney: possible renoprotection via the kidney peptide systems Peptides 2009 30 8 1575 1585
88. Yoshimura M., Yasue H., Ogawa H., Pathophysiological significance and clinical application of ANP and BNP in patients with heart failure Canadian Journal of Physiology and Pharmacology 2001 79 8 730 735 (Pubitemid 32745040)
89. Saito Y., Roles of atrial natriuretic peptide and its therapeutic use Journal of Cardiology 2010 56 3 262 270
90. Nishikimi T., Karasawa T., Inaba C., Ishimura K., Tadokoro K., Koshikawa S., Yoshihara F., Nagaya N., Sakio H., Kangawa K., Matsuoka H., Effects of long-term intravenous administration of adrenomedullin (AM) plus hANP therapy in acute decompensated heart failure: a pilot study Circulation Journal 2009 73 5 892 898
91. Hirose T., Totsune K., Mori N., Mori T., Morimoto R., Metoki H., Asayama K., Kikuya M., Ohkubo T., Kohzuki M., Takahashi K., Imai Y., Expression of adrenomedullin 2/intermedin, a possible reno-protective peptide, is decreased in the kidneys of rats with hypertension or renal failure American Journal of Physiology 2010 299 1 F128 F134