-
1
-
-
0034644472
-
TGFb signaling in growth control, cancer, and heritable disorders
-
Massagué , J., Blain, S. W., and Lo, R. S. (2000) TGFb signaling in growth control, cancer, and heritable disorders. Cell 103, 295 309
-
(2000)
Cell
, vol.103
, pp. 295-309
-
-
Massagué, J.1
Blain, S.W.2
Lo, R.S.3
-
2
-
-
40849133772
-
Role of transforming growth factor-B superfamily signaling pathways in human disease
-
Gordon, K. J. and Blobe, G. C. (2008) Role of transforming growth factor-b superfamily signaling pathways in human disease. Biochim. Biophys. Acta 1782, 197 228
-
(2008)
Biochim. Biophys. Acta.
, vol.1782
, pp. 197-228
-
-
Gordon, K.J.1
Blobe, G.C.2
-
3
-
-
70450189840
-
TGFb family signaling: Novel insights in development and disease
-
Wharton, K. and Derynck, R. (2009) TGFb family signaling: novel insights in development and disease. Development 136, 3691 3697
-
(2009)
Development
, vol.136
, pp. 3691-3697
-
-
Wharton, K.1
Derynck, R.2
-
4
-
-
84859437880
-
Role of Smads in TGFb signaling
-
Heldin, C.-H. and Moustakas, A. (2012) Role of Smads in TGFb signaling. Cell Tissue Res. 347, 21 36
-
(2012)
Cell Tissue Res.
, vol.347
, Issue.21
, pp. 36
-
-
Heldin, C.-H.1
Moustakas, A.2
-
5
-
-
77953695161
-
Cellular and molecular basis for the regulation of inflammation by TGF-b
-
Yoshimura, A., Wakabayashi, Y., and Mori, T. (2010) Cellular and molecular basis for the regulation of inflammation by TGF-b. J. Biochem. 147, 781 792
-
(2010)
J. Biochem.
, vol.147
, pp. 781-792
-
-
Yoshimura, A.1
Wakabayashi, Y.2
Mori, T.3
-
6
-
-
0142104985
-
Smad-dependent and Smad-independent pathways in TGF-b family signalling
-
Derynck, R. and Zhang, Y. E. (2003) Smad-dependent and Smad-independent pathways in TGF-b family signalling. Nature 425, 577 584
-
(2003)
Nature
, vol.425
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
7
-
-
58149213801
-
Non-Smad pathways in TGF-b signaling
-
Zhang, Y. E. (2009) Non-Smad pathways in TGF-b signaling. Cell Res. 19, 128 139
-
(2009)
Cell Res.
, vol.19
, pp. 128-139
-
-
Zhang, Y.E.1
-
8
-
-
63749105896
-
Mechanism of TGF-b signaling to growth arrest, apoptosis, and epithelial-mesenchymal transition
-
Heldin, C.-H., Landström, M., and Moustakas, A. (2009) Mechanism of TGF-b signaling to growth arrest, apoptosis, and epithelial-mesenchymal transition. Curr. Opin. Cell Biol. 21, 166 176
-
(2009)
Curr. Opin. Cell Biol.
, vol.21
, pp. 166-176
-
-
Heldin, C.-H.1
Landström, M.2
Moustakas, A.3
-
9
-
-
70450187617
-
The regulation of TGFb signal transduction
-
Moustakas, A. and Heldin, C.-H. (2009) The regulation of TGFb signal transduction. Development 136, 3699 3714
-
(2009)
Development
, vol.136
, pp. 3699-3714
-
-
Moustakas, A.1
Heldin, C.-H.2
-
10
-
-
77649178841
-
The TAK1-TRAF6 signalling pathway
-
Landström, M. (2010) The TAK1-TRAF6 signalling pathway. Int. J. Biochem. Cell Biol. 42, 585 589
-
(2010)
Int. J. Biochem. Cell Biol.
, vol.42
, pp. 585-589
-
-
Landström, M.1
-
11
-
-
84859443358
-
Non-Smad signaling pathways
-
Mu, Y., Gudey, S. K., and Landström, M. (2012) Non-Smad signaling pathways. Cell Tissue Res. 347, 11 20
-
(2012)
Cell Tissue Res.
, vol.347
, pp. 11-20
-
-
Mu, Y.1
Gudey, S.K.2
Landström, M.3
-
12
-
-
33745515023
-
Tumour microenvironment: TGFb: The molecular Jekyll and Hyde of cancer
-
Bierie, B. and Moses, H. L. (2006) Tumour microenvironment: TGFb: the molecular Jekyll and Hyde of cancer. Nat. Rev. Cancer 6, 506 520
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 506-520
-
-
Bierie, B.1
Moses, H.L.2
-
13
-
-
47549090432
-
TGFb in cancer
-
Massagué , J. (2008) TGFb in cancer. Cell 134, 215 230
-
(2008)
Cell
, vol.134
, pp. 215-230
-
-
Massagué, J.1
-
14
-
-
58149236744
-
Roles of TGFb in metastasis
-
Padua, D. and Massagué , J. (2009) Roles of TGFb in metastasis. Cell Res. 19, 89 102
-
(2009)
Cell Res.
, vol.19
, pp. 89-102
-
-
Padua, D.1
Massagué, J.2
-
15
-
-
78649982907
-
The dynamic roles of TGF-b in cancer
-
Meulmeester, E. and ten Dijke, P. (2011) The dynamic roles of TGF-b in cancer. J. Pathol. 223, 205 218
-
(2011)
J. Pathol.
, vol.223
, pp. 205-218
-
-
Meulmeester, E.1
Ten Dijke, P.2
-
16
-
-
79957809539
-
Cancer early dissemination: Cancerous epithelial-mesenchymal transdifferentiation and transforming growth factor b signalling
-
Sabe, H. (2011) Cancer early dissemination: cancerous epithelial-mesenchymal transdifferentiation and transforming growth factor b signalling. J. Biochem. 149, 633 639
-
(2011)
J. Biochem.
, vol.149
, pp. 633-639
-
-
Sabe, H.1
-
17
-
-
0036144377
-
TGF-b induces apoptosis through Smad-mediated expression of DAP-kinase
-
Jang, C. W., Chen, C. H., Chen, C. C., Chen, J. Y., Su, Y. H., and Chen, R. H. (2002) TGF-b induces apoptosis through Smad-mediated expression of DAP-kinase. Nat. Cell Biol. 4, 51 58
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 51-58
-
-
Jang, C.W.1
Chen, C.H.2
Chen, C.C.3
Chen, J.Y.4
Su, Y.H.5
Chen, R.H.6
-
18
-
-
0036902409
-
Activin/TGF-B induce apoptosis through smad-dependent expression of the lipid phosphatase ship
-
valderrama-Carvajal, H., Cocolakis, E., Lacerte, A., Lee, E. H., Krystal, G., Ali, S., and Lebrun, J. J. (2002) Activin/TGF-b induce apoptosis through Smad-dependent expression of the lipid phosphatase SHIP. Nat. Cell Biol. 4, 963 969
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 963-969
-
-
Valderrama-Carvajal, H.1
Cocolakis, E.2
Lacerte, A.3
Lee, E.H.4
Krystal, G.5
Ali, S.6
Lebrun, J.J.7
-
19
-
-
0036189844
-
Regulation of cell proliferation by Smad proteins
-
ten Dijke, P., Goumans, M. J., Itoh, F., and Itoh, S. (2002) Regulation of cell proliferation by Smad proteins. J. Cell. Physiol. 191, 1 16
-
(2002)
J. Cell. Physiol.
, vol.191
, pp. 1-16
-
-
Ten Dijke, P.1
Goumans, M.J.2
Itoh, F.3
Itoh, S.4
-
20
-
-
0037326526
-
Transforming growth factor-b1 (TGF-b)-Induced apoptosis of prostate cancer cells involves Smad7-Dependent activation of p38 by TGF-b-activated kinase 1 and mitogen-activated protein kinase kinase 3
-
Edlund, S., Bu, S., Schuster, N., Aspenström, P., Heuchel, R., Heldin, N.-E., ten Dijke, P., Heldin, C.- H., and Landström, M. (2003) Transforming growth factor-b1 (TGF-b)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-b-activated kinase 1 and mitogen-activated protein kinase kinase 3. Mol. Biol. Cell. 14, 529 544
-
(2003)
Mol. Biol. Cell.
, vol.14
, pp. 529-544
-
-
Edlund, S.1
Bu, S.2
Schuster, N.3
Aspenström, P.4
Heuchel, R.5
Heldin, N.-E.6
Ten Dijke, P.7
Heldin C.-, H.8
Landström, M.9
-
21
-
-
13444310689
-
Interaction between Smad7 and beta-catenin: Importance for transforming growth factor b-Induced apoptosis
-
Edlund, S., Lee, S. Y., Grimsby, S., Zhang, S., Aspenström, P., Heldin, C.-H., and Landström, M. (2005) Interaction between Smad7 and beta-catenin: importance for transforming growth factor b-induced apoptosis. Mol. Cell. Biol. 25, 1475 1488
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 1475-1488
-
-
Edlund, S.1
Lee, S.Y.2
Grimsby, S.3
Zhang, S.4
Aspenström, P.5
Heldin, C.-H.6
Landström, M.7
-
22
-
-
53349164136
-
The type I TGF-b receptor engages traf6 to activate tak1 in a receptor kinase-independent manner
-
Sorrentino, A., Thakur, N., Grimsby, S., Marcusson, A., von Bulow, v., Schuster, N., Zhang, S., Heldin, C.-H., and Landström, M. (2008) The type I TGF-b receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner. Nat. Cell Biol. 10, 1199 1207
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 1199-1207
-
-
Sorrentino, A.1
Thakur, N.2
Grimsby, S.3
Marcusson, A.4
Von Bulow, V.5
Schuster, N.6
Zhang, S.7
Heldin, C.-H.8
Landström, M.9
-
23
-
-
27644449666
-
Transforming growth factor b-dependent sequential activation of Smad bim, and caspase-9 mediates physiological apoptosis in gastric epithelial cells
-
Ohgushi, M., Kuroki, S., Fukamachi, H., OReilly, L. A., Kuida, K., Strasser, A., and Yonehar, A. S. (2005) Transforming growth factor b-dependent sequential activation of Smad, Bim, and caspase-9 mediates physiological apoptosis in gastric epithelial cells. Mol. Cell. Biol. 25, 10017 10028
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 10017-10028
-
-
Ohgushi, M.1
Kuroki, S.2
Fukamachi, H.3
Oreilly, L.A.4
Kuida, K.5
Strasser, A.6
Yonehar, A.S.7
-
24
-
-
33846821916
-
High TGFb-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene
-
Bruna, A., Darken, R. S., Rojo, F., Ocañ a, A., Peñ uelas, S., Arias, A., Paris, R., Tortosa, A., Mora, J., Baselga, J., and Seoane, J. (2007) High TGFb-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene. Cancer Cell 11, 147 160
-
(2007)
Cancer Cell
, vol.11
, pp. 147-160
-
-
Bruna, A.1
Darken, R.S.2
Rojo, F.3
Ocaña, A.4
Peñuelas, S.5
Arias, A.6
Paris, R.7
Tortosa, A.8
Mora, J.9
Baselga, J.10
Seoane, J.11
-
25
-
-
28944444185
-
Effect of Smad7 expression on metastasis of mouse mammarycarcinoma JygMC(A) cells
-
Azuma, H., Ehata, S., Miyazaki, H., Watabe, T., Maruyama, O., Imamura, T., Sakamoto, T., Kiyama, S., Kiyama, Y., Ubai, T., Inamoto, T., Takahara, S., Itoh, Y., Otsuki, Y., Katsuoka, Y., Miyazono, K., and Horie, S. (2005) Effect of Smad7 expression on metastasis of mouse mammarycarcinoma JygMC(A) cells. J. Natl. Cancer Inst. 97, 1734 1746
-
(2005)
J. Natl. Cancer Inst.
, vol.97
, pp. 1734-1746
-
-
Azuma, H.1
Ehata, S.2
Miyazaki, H.3
Watabe, T.4
Maruyama, O.5
Imamura, T.6
Sakamoto, T.7
Kiyama, S.8
Kiyama, Y.9
Ubai, T.10
Inamoto, T.11
Takahara, S.12
Itoh, Y.13
Otsuki, Y.14
Katsuoka, Y.15
Miyazono, K.16
Horie, S.17
-
26
-
-
78650655487
-
Autocrine TGF-b protects breast cancer cells from apoptosis through reduction of BH3-only protein
-
Hoshino, Y., Katsuno, Y., Ehata, S., and Miyazono, K. (2011) Autocrine TGF-b protects breast cancer cells from apoptosis through reduction of BH3-only protein, Bim. J. Biochem. 149, 55 65
-
(2011)
Bim. J. Biochem.
, vol.149
, pp. 55-65
-
-
Hoshino, Y.1
Katsuno, Y.2
Ehata, S.3
Miyazono, K.4
-
27
-
-
84856221154
-
XC1, a target of polycomb, inhibits metastasis of breast cancer cells
-
Du, J., Li, L., Ou, Z., Kong, C., Zhang, Y., Dong, Z., Zhu, S., Jiang, H., Shao, Z., Huang, B., and Lu, J. (2012) FOXC1, a target of polycomb, inhibits metastasis of breast cancer cells. Breast Cancer Res. Treat. 131, 65 73
-
(2012)
Breast Cancer Res. Treat.
, vol.131
, pp. 65-73
-
-
Du, J.1
Li, L.2
Ou, Z.3
Kong, C.4
Zhang, Y.5
Dong, Z.6
Zhu, S.7
Jiang, H.8
Shao, Z.9
Huang, B.10
Lu, J.11
-
28
-
-
77952821751
-
FOXC1 is a potential prognostic biomarker with functional significance in basal-Like breast cancer
-
Ray, P. S., Wang, J., Qu, Y., Sim, M. S., Shamonki, J., Bagaria, S. P., Ye, X., Liu, B., Elashoff, D., Hoon, D. S., Walter, M. A., Martens, J. W., Richardson, A. L., Giuliano, A. E., and Cui, X. (2010) FOXC1 is a potential prognostic biomarker with functional significance in basal-like breast cancer. Cancer Res. 70, 3870 3876
-
(2010)
Cancer Res.
, vol.70
, pp. 3870-3876
-
-
Ray, P.S.1
Wang, J.2
Qu, Y.3
Sim, M.S.4
Shamonki, J.5
Bagaria, S.P.6
Ye, X.7
Liu, B.8
Elashoff, D.9
Hoon, D.S.10
Walter, M.A.11
Martens, J.W.12
Richardson, A.L.13
Giuliano, A.E.14
Cui, X.15
-
29
-
-
84862290709
-
FOXC1 regulates the functions of human basal-Like breast cancer cells by activating NF-k B signaling
-
in press) 30. Zhou, Y., Kato, H., Asanoma, K., Kondo, H., Arima, T., Kato, K., Matsuda, T., and Wake, N. dentification of FOXC1 as a TGF-b1 responsive gene and its involvement in negative regulation of cell growth
-
Wang, J., Ray, P. S., Sim, M. S., Zhou, X. Z., Lu, K. P., Lee, A. v., Lin, X., Bagaria, S. P., Giuliano, A. E., and Cui, X. (2012) FOXC1 regulates the functions of human basal-like breast cancer cells by activating NF-k B signaling. Oncogene (in press) 30. Zhou, Y., Kato, H., Asanoma, K., Kondo, H., Arima, T., Kato, K., Matsuda, T., and Wake, N. (2002) Identification of FOXC1 as a TGF-b1 responsive gene and its involvement in negative regulation of cell growth. Genomics 80, 465-472
-
(2012)
Genomics
, vol.80
, pp. 465-472
-
-
Wang, J.1
Ray, P.S.2
Sim, M.S.3
Zhou, X.Z.4
Lu, K.P.5
Lee, A.V.6
Lin, X.7
Bagaria, S.P.8
Giuliano, A.E.9
Cui, X.10
-
30
-
-
35448997708
-
Transforming growth factor-b promotes survival of mammary carcinoma cells through induction of antiapoptotic transcription factor DEC1
-
Ehata, S., Hanyu, A., Hayashi, M., Aburatani, H., Kato, Y., Fujime, M., Saitoh, M., Miyazawa, K., Imamura, T., and Miyazono, K. (2007) Transforming growth factor-b promotes survival of mammary carcinoma cells through induction of antiapoptotic transcription factor DEC1. Cancer Res. 67, 9694-9703
-
(2007)
Cancer Res.
, vol.67
, pp. 9694-9703
-
-
Ehata, S.1
Hanyu, A.2
Hayashi, M.3
Aburatani, H.4
Kato, Y.5
Fujime, M.6
Saitoh, M.7
Miyazawa, K.8
Imamura, T.9
Miyazono, K.10
|