Isolation of a glucosamine binding leguminous lectin with mitogenic activity towards splenocytes and anti-proliferative activity towards tumor cells

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Chan, Yau Sang ^a   Wong, Jack Ho ^a   Fang, Evandro Fei ^b   Pan, Wenliang ^a   Ng, Tzi Bun ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BROWN KIDNEY BEAN LECTIN; GAMMA INTERFERON; GLUCOSAMINE; INTERLEUKIN 2; LECTIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ANIMAL CELL; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL STRAIN HEPG2; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG ISOLATION; ENDOPLASMIC RETICULUM STRESS; FAST PROTEIN LIQUID CHROMATOGRAPHY; FLOW CYTOMETRY; GEL FILTRATION; GENE EXPRESSION; HEMAGGLUTINATION; IC 50; MITOGENESIS; MOUSE; NONHUMAN; PH; PHASEOLUS VULGARIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; SPLEEN CELL; TEMPERATURE DEPENDENCE; TUMOR CELL; UNFOLDED PROTEIN RESPONSE; WESTERN BLOTTING;

ANIMALS; BASE SEQUENCE; CELL PROLIFERATION; CYTOKINES; DNA PRIMERS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FABACEAE; GLUCOSAMINE; HEMAGGLUTINATION TESTS; HYDROGEN-ION CONCENTRATION; LECTINS; MICE; MICE, INBRED BALB C; MITOGENS; POLYMERASE CHAIN REACTION; PROTEIN BINDING; SPLEEN; TEMPERATURE;

EID: 84862259256     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038961     Document Type: Article

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