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Volumn 97, Issue 6, 2012, Pages 849-853

Multiple myeloma shows no intra-disease clustering of immunoglobulin heavy chain genes

(25)  Ferrero, Simone a   Capello, Daniela b   Svaldi, Mirija c   Boi, Michela a,d   Gatti, Daniela c   Drandi, Daniela a   Rossi, Davide b   Barbiero, Sara a   Mantoan, Barbara a   Mantella, Elisabetta a   Zanni, Manuela a   Ghione, Paola a   Larocca, Alessandra a   Passera, Roberto a   Bertoni, Francesco d   Gattei, Valter e   Forconi, Francesco f   Laurenti, Luca g   del Poeta, Giovanni h   Marasca, Roberto i   more..


Author keywords

Antigen selection; Heavy chain gene; Immunoglobulin; Multiple myeloma

Indexed keywords

ARTICLE; CHRONIC LYMPHATIC LEUKEMIA; COMPLEMENTARITY DETERMINING REGION; GENE; GENE REARRANGEMENT; HUMAN; IGHD GENE; IGHJ GENE; IGHV GENE; IMMUNOGLOBULIN HEAVY CHAIN GENE; MANTLE CELL LYMPHOMA; MARGINAL ZONE LYMPHOMA; MULTIPLE MYELOMA; PLASMA CELL; SEQUENCE ANALYSIS; SOMATIC HYPERMUTATION;

EID: 84862147703     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2011.052852     Document Type: Article
Times cited : (13)

References (31)
  • 1
    • 0029664523 scopus 로고    scopus 로고
    • VH gene usage is multiple myeloma: Complete absence of the VH4.21 (VH4-34) gene
    • Rettig MB, Vescio RA, Cao J, Wu CH, Lee JC, Han E, et al. VH gene usage is multiple myeloma: complete absence of the VH4.21 (VH4-34) gene. Blood. 1996;87(7):2846-52.
    • (1996) Blood. , vol.87 , Issue.7 , pp. 2846-2852
    • Rettig, M.B.1    Vescio, R.A.2    Cao, J.3    Wu, C.H.4    Lee, J.C.5    Han, E.6
  • 2
    • 0032081314 scopus 로고    scopus 로고
    • Analysis of VH genes in follicular and diffuse lymphoma shows ongoing somatic mutation and multiple isotype transcripts in early disease with changes during disease progression
    • Ottensmeier CH, Thompsett AR, Zhu D, Wilkins BS, Sweetenham JW, Stevenson FK. Analysis of VH genes in follicular and diffuse lymphoma shows ongoing somatic mutation and multiple isotype transcripts in early disease with changes during disease progression. Blood. 1998;91(11):4292-9.
    • (1998) Blood. , vol.91 , Issue.11 , pp. 4292-4299
    • Ottensmeier, C.H.1    Thompsett, A.R.2    Zhu, D.3    Wilkins, B.S.4    Sweetenham, J.W.5    Stevenson, F.K.6
  • 3
    • 0033567968 scopus 로고    scopus 로고
    • Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia
    • Damle RN, Wasil T, Fais F, Ghiotto F, Valetto A, Allen SL, et al. Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. Blood. 1999;94:1840-7.
    • (1999) Blood. , vol.94 , pp. 1840-1847
    • Damle, R.N.1    Wasil, T.2    Fais, F.3    Ghiotto, F.4    Valetto, A.5    Allen, S.L.6
  • 4
    • 0033567907 scopus 로고    scopus 로고
    • Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia
    • Hamblin TJ, Davis Z, Gardiner A, Oscier DG, Stevenson FK. Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood. 1999;94(6):1848-54.
    • (1999) Blood. , vol.94 , Issue.6 , pp. 1848-1854
    • Hamblin, T.J.1    Davis, Z.2    Gardiner, A.3    Oscier, D.G.4    Stevenson, F.K.5
  • 5
    • 0141889260 scopus 로고    scopus 로고
    • VH mutation status and VDJ rearrangement structure in mantle cell lymphoma: Correlation with genomic aberrations, clinical characteristics, and outcome
    • Kienle D, Kröber A, Katzenberger T, Ott G, Leupolt E, Barth TF, et al. VH mutation status and VDJ rearrangement structure in mantle cell lymphoma: correlation with genomic aberrations, clinical characteristics, and outcome. Blood. 2003;102(8): 3003-9.
    • (2003) Blood. , vol.102 , Issue.8 , pp. 3003-3009
    • Kienle, D.1    Kröber, A.2    Katzenberger, T.3    Ott, G.4    Leupolt, E.5    Barth, T.F.6
  • 7
    • 33745757786 scopus 로고    scopus 로고
    • Immunoglobulin genes in multiple myeloma: Expressed and nonexpressed repertoires, heavy and light chain pairings and somatic mutation patterns in a series of 101 cases
    • Hadzidimitriou A, Stamatopoulos K, Belessi C, Lalayianni C, Stavroyianni N, Smilevska T, et al. Immunoglobulin genes in multiple myeloma: expressed and nonexpressed repertoires, heavy and light chain pairings and somatic mutation patterns in a series of 101 cases. Haematologica. 2006;91(6):781-7.
    • (2006) Haematologica. , vol.91 , Issue.6 , pp. 781-787
    • Hadzidimitriou, A.1    Stamatopoulos, K.2    Belessi, C.3    Lalayianni, C.4    Stavroyianni, N.5    Smilevska, T.6
  • 8
    • 0032532668 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors
    • Fais F, Ghiotto F, Hashimoto S, Sellars B, Valetto A, Allen SL, et al. Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors. J Clin Invest. 1998;102(8):1515-25.
    • (1998) J Clin Invest. , vol.102 , Issue.8 , pp. 1515-1525
    • Fais, F.1    Ghiotto, F.2    Hashimoto, S.3    Sellars, B.4    Valetto, A.5    Allen, S.L.6
  • 9
    • 7244232709 scopus 로고    scopus 로고
    • Subsets with restricted immunoglobulin gene rearrangement features indicate a role for antigen selection in the development of chronic lymphocytic leukemia
    • Tobin G, Thunberg U, Karlsson K, Murray F, Laurell A, Willander K, et al. Subsets with restricted immunoglobulin gene rearrangement features indicate a role for antigen selection in the development of chronic lymphocytic leukemia. Blood. 2004;104(9): 2879-85.
    • (2004) Blood. , vol.104 , Issue.9 , pp. 2879-2885
    • Tobin, G.1    Thunberg, U.2    Karlsson, K.3    Murray, F.4    Laurell, A.5    Willander, K.6
  • 10
    • 33846108722 scopus 로고    scopus 로고
    • Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: Pathogenetic implications and clinical correlations
    • Stamatopoulos K, Belessi C, Moreno C, Boudjograh M, Guida G, Smilevska T, et al. Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: Pathogenetic implications and clinical correlations. Blood. 2007;109(1):259-70.
    • (2007) Blood. , vol.109 , Issue.1 , pp. 259-270
    • Stamatopoulos, K.1    Belessi, C.2    Moreno, C.3    Boudjograh, M.4    Guida, G.5    Smilevska, T.6
  • 11
    • 58549100059 scopus 로고    scopus 로고
    • Molecular and clinical features of chronic lymphocytic leukaemia with stereotyped B cell receptors: Results from an Italian multicentre study
    • Bomben R, Dal Bo M, Capello D, Forconi F, Maffei R, Laurenti L, et al. Molecular and clinical features of chronic lymphocytic leukaemia with stereotyped B cell receptors: results from an Italian multicentre study. Br J Haematol. 2009;144(4):492-506.
    • (2009) Br J Haematol. , vol.144 , Issue.4 , pp. 492-506
    • Bomben, R.1    Dal Bo, M.2    Capello, D.3    Forconi, F.4    Maffei, R.5    Laurenti, L.6
  • 12
    • 74949107027 scopus 로고    scopus 로고
    • The normal IGHV1-69-derived B-cell repertoire contains stereotypic patterns characteristic of unmutated CLL
    • Forconi F, Potter KN, Wheatley I, Darzentas N, Sozzi E, Stamatopoulos K, et al. The normal IGHV1-69-derived B-cell repertoire contains stereotypic patterns characteristic of unmutated CLL. Blood. 2010;115(1):71-7.
    • (2010) Blood. , vol.115 , Issue.1 , pp. 71-77
    • Forconi, F.1    Potter, K.N.2    Wheatley, I.3    Darzentas, N.4    Sozzi, E.5    Stamatopoulos, K.6
  • 13
    • 80052929598 scopus 로고    scopus 로고
    • Is there a role for antigen selection in mantle cell lymphoma? Immunogenetic support from a series of 807 cases
    • Hadzidimitriou A, Agathangelidis A, Darzentas N, Murray F, Delfau-Larue MH, Bredo Pedersen L, et al. Is there a role for antigen selection in mantle cell lymphoma? Immunogenetic support from a series of 807 cases. Blood. 2011;118(11):3088-95.
    • (2011) Blood. , vol.118 , Issue.11 , pp. 3088-3095
    • Hadzidimitriou, A.1    Agathangelidis, A.2    Darzentas, N.3    Murray, F.4    Delfau-Larue, M.H.5    Bredo Pedersen, L.6
  • 15
    • 3242777803 scopus 로고    scopus 로고
    • Advances in biology of multiple myeloma: Clinical applications
    • Hideshima T, Bergsagel PL, Kuehl WM, Anderson KC. Advances in biology of multiple myeloma: clinical applications. Blood. 2004;104(3):607-18.
    • (2004) Blood. , vol.104 , Issue.3 , pp. 607-618
    • Hideshima, T.1    Bergsagel, P.L.2    Kuehl, W.M.3    Anderson, K.C.4
  • 17
    • 0028246112 scopus 로고
    • Evidence that the clonogenic cell in multiple myeloma originates from a pre-switched but somatically mutated B cell
    • Bakkus MH, Van Riet I, Van Camp B, Thielemans K. Evidence that the clonogenic cell in multiple myeloma originates from a pre-switched but somatically mutated B cell. Br J Haematol. 1994;87(1):68-74.
    • (1994) Br J Haematol. , vol.87 , Issue.1 , pp. 68-74
    • Bakkus, M.H.1    van Riet, I.2    van Camp, B.3    Thielemans, K.4
  • 18
    • 77951625298 scopus 로고    scopus 로고
    • Major tumor shrinking and persistent molecular remissions after consolidation with bortezomib, thalidomide, and dexamethasone in patients with autografted myeloma
    • Ladetto M, Pagliano G, Ferrero S, Cavallo F, Drandi D, Santo L, et al. Major tumor shrinking and persistent molecular remissions after consolidation with bortezomib, thalidomide, and dexamethasone in patients with autografted myeloma. J Clin Oncol. 2010;28(12):2077-84.
    • (2010) J Clin Oncol. , vol.28 , Issue.12 , pp. 2077-2084
    • Ladetto, M.1    Pagliano, G.2    Ferrero, S.3    Cavallo, F.4    Drandi, D.5    Santo, L.6
  • 19
    • 0030698409 scopus 로고    scopus 로고
    • A novel nested-PCR strategy for the detection of rearranged immunoglobulin heavy-chain genes in B cell tumors
    • Voena C, Ladetto M, Astolfi M, Provan D, Gribben JG, Boccadoro M, et al. A novel nested-PCR strategy for the detection of rearranged immunoglobulin heavy-chain genes in B cell tumors. Leukemia. 1997; 11(10):1793-8.
    • (1997) Leukemia. , vol.11 , Issue.10 , pp. 1793-1798
    • Voena, C.1    Ladetto, M.2    Astolfi, M.3    Provan, D.4    Gribben, J.G.5    Boccadoro, M.6
  • 20
    • 9644277298 scopus 로고    scopus 로고
    • IMGT/JunctionAnalysis: The first tool for the analysis of the immunoglobulin and T cell receptor complex V-J and V-D-J JUNCTIONs
    • Yousfi Monod M, Giudicelli V, Chaume D, Lefranc MP. IMGT/JunctionAnalysis: the first tool for the analysis of the immunoglobulin and T cell receptor complex V-J and V-D-J JUNCTIONs. Bioinformatics. 2004;20(Suppl 1):i379-85.
    • (2004) Bioinformatics. , vol.20 , Issue.SUPPL. 1
    • Yousfi Monod, M.1    Giudicelli, V.2    Chaume, D.3    Lefranc, M.P.4
  • 21
    • 0028986909 scopus 로고
    • Representation of rearranged VH gene segments in the human adult antibody repertoire
    • Suzuki I, Pfister L, Glas A, Nottenburg C, Milner EC. Representation of rearranged VH gene segments in the human adult antibody repertoire. J Immunol. 1995;154(8): 3902-11.
    • (1995) J Immunol. , vol.154 , Issue.8 , pp. 3902-3911
    • Suzuki, I.1    Pfister, L.2    Glas, A.3    Nottenburg, C.4    Milner, E.C.5
  • 23
    • 0030610529 scopus 로고    scopus 로고
    • Differential effects of selection and somatic hypermutation on human peripheral CD5(+)/IgM+ and CD5(-)/IgM+ B cells
    • Brezinschek HP, Foster SJ, Brezinschek RI, Dörner T, Domiati-Saad R, Lipsky PE. Differential effects of selection and somatic hypermutation on human peripheral CD5(+)/IgM+ and CD5(-)/IgM+ B cells. J Clin Invest. 1997;99(10):2488-501.
    • (1997) J Clin Invest. , vol.99 , Issue.10 , pp. 2488-2501
    • Brezinschek, H.P.1    Foster, S.J.2    Brezinschek, R.I.3    Dörner, T.4    Domiati-Saad, R.5    Lipsky, P.E.6
  • 24
    • 0031570413 scopus 로고    scopus 로고
    • The human heavy chain Ig V region gene repertoire is biased at all stages of B cell ontogeny, including early pre-B cells
    • Kraj P, Rao SP, Glas AM, Hardy RR, Milner EC, Silberstein LE. The human heavy chain Ig V region gene repertoire is biased at all stages of B cell ontogeny, including early pre-B cells. J Immunol. 1997;158(12):5824-32.
    • (1997) J Immunol. , vol.158 , Issue.12 , pp. 5824-5832
    • Kraj, P.1    Rao, S.P.2    Glas, A.M.3    Hardy, R.R.4    Milner, E.C.5    Silberstein, L.E.6
  • 25
    • 0030864457 scopus 로고    scopus 로고
    • Human Ig heavy chain CDR3 regions in adult bone marrow pre-B cells display an adult phenotype of diversity: Evidence for structural selection of DH amino acid sequences
    • Raaphorst FM, Raman CS, Tami J, Fischbach M, Sanz I. Human Ig heavy chain CDR3 regions in adult bone marrow pre-B cells display an adult phenotype of diversity: evidence for structural selection of DH amino acid sequences. Int Immunol. 1997; 9(10):1503-15.
    • (1997) Int Immunol. , vol.9 , Issue.10 , pp. 1503-1515
    • Raaphorst, F.M.1    Raman, C.S.2    Tami, J.3    Fischbach, M.4    Sanz, I.5
  • 26
    • 0032694334 scopus 로고    scopus 로고
    • Immunoglobulin VH gene expression in human aging
    • Wang X, Stollar BD. Immunoglobulin VH gene expression in human aging. Clin Immunol 1999;93:132-42.
    • (1999) Clin Immunol , vol.93 , pp. 132-142
    • Wang, X.1    Stollar, B.D.2
  • 28
    • 4344704897 scopus 로고    scopus 로고
    • Multiple distinct sets of stereotyped antigen receptors indicate a role for antigen in promoting chronic lymphocytic leukemia
    • Messmer BT, Albesiano E, Efremov DG, Ghiotto F, Allen SL, Kolitz J, et al. Multiple distinct sets of stereotyped antigen receptors indicate a role for antigen in promoting chronic lymphocytic leukemia. J Exp Med. 2004;200(4):519-25.
    • (2004) J Exp Med. , vol.200 , Issue.4 , pp. 519-525
    • Messmer, B.T.1    Albesiano, E.2    Efremov, D.G.3    Ghiotto, F.4    Allen, S.L.5    Kolitz, J.6
  • 29
    • 74249107417 scopus 로고    scopus 로고
    • A different ontogenesis for chronic lymphocytic leukemia cases carrying stereotyped antigen receptors: Molecular and computational evidence
    • Darzentas N, Hadzidimitriou A, Murray F, Hatzi K, Josefsson P, Laoutaris N, et al. A different ontogenesis for chronic lymphocytic leukemia cases carrying stereotyped antigen receptors: molecular and computational evidence. Leukemia. 2010;24(1):125-32.
    • (2010) Leukemia. , vol.24 , Issue.1 , pp. 125-132
    • Darzentas, N.1    Hadzidimitriou, A.2    Murray, F.3    Hatzi, K.4    Josefsson, P.5    Laoutaris, N.6
  • 30
    • 77956551877 scopus 로고    scopus 로고
    • Highthroughput immunoglobulin repertoire analysis distinguishes between human IgM memory and switched memory B-cell populations
    • Wu YC, Kipling D, Leong HS, Martin V, Ademokun AA, Dunn-Walters DK. Highthroughput immunoglobulin repertoire analysis distinguishes between human IgM memory and switched memory B-cell populations. Blood. 2010;116(7):1070-8.
    • (2010) Blood. , vol.116 , Issue.7 , pp. 1070-1078
    • Wu, Y.C.1    Kipling, D.2    Leong, H.S.3    Martin, V.4    Ademokun, A.A.5    Dunn-Walters, D.K.6
  • 31
    • 13544275555 scopus 로고    scopus 로고
    • Geographic patterns and pathogenetic implications of IGHV gene usage in chronic lymphocytic leukemia: The lesson of the IGHV3-21 gene
    • Ghia P, Stamatopoulos K, Belessi C, Moreno C, Stella S, Guida G, et al. Geographic patterns and pathogenetic implications of IGHV gene usage in chronic lymphocytic leukemia: the lesson of the IGHV3-21 gene. Blood. 2005;105(4):1678-85.
    • (2005) Blood. , vol.105 , Issue.4 , pp. 1678-1685
    • Ghia, P.1    Stamatopoulos, K.2    Belessi, C.3    Moreno, C.4    Stella, S.5    Guida, G.6


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