메뉴 건너뛰기




Volumn 125, Issue 23, 2012, Pages 2824-2826

Nitrate-nitrite-nitric oxide pathway in pulmonary arterial hypertension therapeutics

Author keywords

[No Author keywords available]

Indexed keywords

ALLOPURINOL; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN RECEPTOR ANTAGONIST; NITRATE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRITE; PHOSPHODIESTERASE V INHIBITOR; PROSTANOID; SODIUM NITRITE; XANTHINE OXIDASE;

EID: 84862127206     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.112.107821     Document Type: Review
Times cited : (40)

References (30)
  • 1
    • 84859644104 scopus 로고    scopus 로고
    • Reactive oxygen and nitrogen species in pulmonary hypertension
    • Tabima DM, Frizzell S, Gladwin MT. Reactive oxygen and nitrogen species in pulmonary hypertension. Free Radic Biol Med. 2012;52:1970-1986.
    • (2012) Free Radic Biol Med. , vol.52 , pp. 1970-1986
    • Tabima, D.M.1    Frizzell, S.2    Gladwin, M.T.3
  • 2
    • 38849162730 scopus 로고    scopus 로고
    • The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics
    • Lundberg JO, Weitzberg E, Gladwin MT. The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics. Nat Rev Drug Discov. 2008;7:156-167.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 156-167
    • Lundberg, J.O.1    Weitzberg, E.2    Gladwin, M.T.3
  • 3
    • 74549201021 scopus 로고    scopus 로고
    • Nitrite potently inhibits hypoxic and inflammatory pulmonary arterial hypertension and smooth muscle proliferation via xanthine oxidoreductase- dependent nitric oxide generation
    • Zuckerbraun BS, Shiva S, Ifedigbo E, Mathier MA, Mollen KP, Rao J, Bauer PM, Choi JJW, Curtis E, Choi AMK, Gladwin MT. Nitrite potently inhibits hypoxic and inflammatory pulmonary arterial hypertension and smooth muscle proliferation via xanthine oxidoreductase-dependent nitric oxide generation. Circulation. 2010;121:98-109.
    • (2010) Circulation , vol.121 , pp. 98-109
    • Zuckerbraun, B.S.1    Shiva, S.2    Ifedigbo, E.3    Mathier, M.A.4    Mollen, K.P.5    Rao, J.6    Bauer, P.M.7    Jjw, C.8    Curtis, E.9    Amk, C.10    Gladwin, M.T.11
  • 5
    • 84862125705 scopus 로고    scopus 로고
    • Dietary nitrate ameliorates pulmonary hypertension: Cytoprotective role for endothelial nitric oxide synthase and xanthine oxidoreductase
    • Baliga RS, Milsom AB, Ghosh SM, Trinder SL, MacAllister RJ, Ahluwalia A, Hobbs AJ. Dietary nitrate ameliorates pulmonary hypertension: cytoprotective role for endothelial nitric oxide synthase and xanthine oxidoreductase. Circulation. 2012;125:2922-2932.
    • (2012) Circulation , vol.125 , pp. 2922-2932
    • Baliga, R.S.1    Milsom, A.B.2    Ghosh, S.M.3    Trinder, S.L.4    MacAllister, R.J.5    Ahluwalia, A.6    Hobbs, A.J.7
  • 7
    • 0035054644 scopus 로고    scopus 로고
    • Nitrite-derived nitric oxide: A possible mediator of 'acidic-metabolic' vasodilation
    • Modin A, Björne H, Herulf M, Alving K, Weitzberg E, Lundberg JON. Nitrite-derived nitric oxide: a possible mediator of 'acidic-metabolic' vasodilation. Acta Physiol Scand. 2001;171:9-16.
    • (2001) Acta Physiol Scand , vol.171 , pp. 9-16
    • Modin, A.1    Björne, H.2    Herulf, M.3    Alving, K.4    Weitzberg, E.5    Jon, L.6
  • 16
    • 0028143644 scopus 로고
    • Intragastric nitric oxide production in humans: Measurements in expelled air
    • Lundberg JO, Weitzberg E, Lundberg JE, Alving K. Intragastric nitric oxide production in humans: Measurements in expelled air. Gut. 1994;35:1543-1546.
    • (1994) Gut , vol.35 , pp. 1543-1546
    • Lundberg, J.O.1    Weitzberg, E.2    Lundberg, J.E.3    Alving, K.4
  • 20
    • 0032496394 scopus 로고    scopus 로고
    • Xanthine oxidoreductase catalyses the reduction of nitrates and nitrite to nitric oxide under hypoxic conditions
    • Millar TM, Stevens CR, Benjamin N, Eisenthal R, Harrison R, Blake DR. Xanthine oxidoreductase catalyses the reduction of nitrates and nitrite to nitric oxide under hypoxic conditions. FEBS Letters. 1998;427:225-228.
    • (1998) FEBS Letters , vol.427 , pp. 225-228
    • Millar, T.M.1    Stevens, C.R.2    Benjamin, N.3    Eisenthal, R.4    Harrison, R.5    Blake, D.R.6
  • 21
    • 79551475073 scopus 로고    scopus 로고
    • Nitrite in pulmonary arterial hypertension: Therapeutic avenues in the setting of dysregulated arginine/nitric oxide synthase signalling
    • Zuckerbraun BS, George P, Gladwin MT. Nitrite in pulmonary arterial hypertension: Therapeutic avenues in the setting of dysregulated arginine/nitric oxide synthase signalling. Cardiovasc Res. 2011;89:542-552.
    • (2011) Cardiovasc Res , vol.89 , pp. 542-552
    • Zuckerbraun, B.S.1    George, P.2    Gladwin, M.T.3
  • 23
    • 53449085187 scopus 로고    scopus 로고
    • The functional nitrite reductase activity of the heme-globins
    • Gladwin MT, Kim-Shapiro DB. The functional nitrite reductase activity of the heme-globins. Blood. 2008;112:2636-2647.
    • (2008) Blood , vol.112 , pp. 2636-2647
    • Gladwin, M.T.1    Kim-Shapiro, D.B.2
  • 24
    • 72249108763 scopus 로고    scopus 로고
    • Generation of nitric oxide from nitrite by carbonic anhydrase: A possible link between metabolic activity and vasodilation
    • Aamand R, Dalsgaard T, Jensen FB, Simonsen U, Roepstorff A, Fago A. Generation of nitric oxide from nitrite by carbonic anhydrase: A possible link between metabolic activity and vasodilation. Am J Physiol Heart Circ Physiol. 2009;297:H2068-H2074.
    • (2009) Am J Physiol Heart Circ Physiol , vol.297
    • Aamand, R.1    Dalsgaard, T.2    Jensen, F.B.3    Simonsen, U.4    Roepstorff, A.5    Fago, A.6
  • 30
    • 84861318584 scopus 로고    scopus 로고
    • Normoxic cyclic gmp-independent oxidative signaling by nitrite enhances airway epithelial cell proliferation and wound healing
    • Mar 8. [Epub ahead of print]
    • Wang L, Frizzell SA, Zhao X, Gladwin MT. Normoxic cyclic gmp-independent oxidative signaling by nitrite enhances airway epithelial cell proliferation and wound healing. Nitric Oxide. 2012 Mar 8. [Epub ahead of print].
    • (2012) Nitric Oxide
    • Wang, L.1    Frizzell, S.A.2    Zhao, X.3    Gladwin, M.T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.