Inhaled nebulized nitrite is a hypoxia-sensitive NO-dependent selective pulmonary vasodilator

Nature Medicine

Volumn 10, Issue 10, 2004, Pages 1122-1127

  Hunter, Christian J ^a,b,c,d   Dejam, André ^c   Blood, Arlin B ^d   Shields, Howard ^e   Kim Shapiro, Daniel B ^e   Machado, Roberto F ^a,b,c   Tarekegn, Selamawit ^a   Mulla, Neda ^d   Hopper, Andrew O ^d   Schechter, Alan N ^c   Power, Gordon G ^d   Gladwin, Mark T ^a,b,c  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^d LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e WAKE FOREST UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; DEOXYHEMOGLOBIN; HEME; HEMOGLOBIN DERIVATIVE; HEMOPROTEIN; IRON NITROSYL HEMOGLOBIN; METHEMOGLOBIN; NITRIC OXIDE; NITRITE; UNCLASSIFIED DRUG;

AEROSOL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; CONTROLLED STUDY; DEOXYGENATION; HYPOXEMIA; HYPOXIC CELL; HYPOXIC LUNG VASOCONSTRICTION; LAMB; LUNG BLOOD FLOW; NEWBORN; NEWBORN DISEASE; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PH MEASUREMENT; PRIORITY JOURNAL; PROTON TRANSPORT; PULMONARY HYPERTENSION; REDUCTION; SYSTEMIC DISEASE; VASODILATATION;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ADMINISTRATION, INHALATION; AEROSOLS; ANIMALS; ANIMALS, NEWBORN; ANOXIA; BLOOD PRESSURE; CARDIAC OUTPUT; DISEASE MODELS, ANIMAL; HEMOGLOBINS; HUMANS; HYDROGEN-ION CONCENTRATION; INFANT, NEWBORN; METHEMOGLOBIN; NITRIC OXIDE; OXYGEN; PERSISTENT FETAL CIRCULATION SYNDROME; SHEEP; SODIUM NITRITE; VASODILATOR AGENTS;

ANIMALIA; LAMB; OVIS ARIES;

EID: 7044250715     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm1109     Document Type: Article

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