Development and validation of a liquid chromatography-mass spectrometry method for the determination of verticinone in rat plasma and its application to pharmacokinetic study

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 878, Issue 23, 2010, Pages 2067-2071

  Wu, Xiao ^a   Chen, Hui ^a   Sun, Jianguo ^b   Peng, Ying ^b   Liang, Yan ^b   Wang, Guangji ^b   Wu, Jizhou ^a   Zhang, Peng ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

LC ESI MS; Pharmacokinetic studies; Rat; Verticinone

Indexed keywords

AMMONIA HYDROXIDE; CALIBRATION CURVES; CHROMATOGRAPHIC SEPARATIONS; CONCENTRATION RANGES; ETHYL ACETATES; FRITILLARIA; GRADIENT ELUTION; INTERNAL STANDARDS; LC-ESI-MS; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; LOWER LIMIT OF QUANTIFICATIONS; MOBILE PHASE; ORAL ADMINISTRATION; PHARMACOKINETIC STUDIES; PLASMA SAMPLES; POSITIVE ELECTROSPRAY IONIZATION; RAT PLASMA; SELECTED ION MONITORING; SIMPLE LIQUIDS; VALIDATED METHODS;

CHEMICAL ANALYSIS; ELECTROSPRAY IONIZATION; ESTERS; IONIZATION; LIQUIDS; MASS SPECTROMETRY; METHANOL; PARTICLE DETECTORS; PHARMACOKINETICS; PLASMA (HUMAN); SOLVENT EXTRACTION;

LIQUID CHROMATOGRAPHY;

ALKALOID; HUPEHENINE; METHANOL; UNCLASSIFIED DRUG; VERTICINONE; WATER; CEVANE DERIVATIVE; VERTICINE;

ANIMAL EXPERIMENT; ARTICLE; CALIBRATION; CONTROLLED STUDY; DRUG ABSORPTION; DRUG DETERMINATION; DRUG STABILITY; DRUG STRUCTURE; ELECTROSPRAY; ION MONITORING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETER; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; BLOOD; CHEMISTRY; ISOLATION AND PURIFICATION; LIMIT OF DETECTION; MASS SPECTROMETRY; ORAL DRUG ADMINISTRATION; PROCEDURES; REPRODUCIBILITY; SPRAGUE DAWLEY RAT; STANDARD; TIME; VALIDATION STUDY;

ADMINISTRATION, ORAL; ALKALOIDS; ANIMALS; CEVANES; CHROMATOGRAPHY, LIQUID; DRUG STABILITY; LIMIT OF DETECTION; MASS SPECTROMETRY; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; TIME FACTORS;

FRITILLARIA HUPEHENSIS; RATTUS;

EID: 77955056450     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2010.06.004     Document Type: Article

References (21)

1. Xu D.M., Xu Y.J. Chin. Tradit. Herb. Drugs 1991, 22:132.
2. Yu X.L., Ji H., Wang C.L., Li P. Chin. Tradit. Herb. Drugs 2000, 31:313.
3. Xiao P.G. Chin. J. Chin. Mater. Med. 2002, 27:726.
4. Zhang Y.H., Ruan H.L., Zeng F.B., Pi H.F., Zhao W., Wu J.Z. Chin. Tradit. Herb. Drugs 2003, 34:1016.
5. Qian B.C., Xu H.J. Yao Xue Xue Bao 1985, 20:306.
6. Zhang Y.H., Ruan H.L., Pi H.F., Cai J.Y., Zeng F.B., Zhao W., Wu J.Z. Chin. Tradit. Herb. Drugs 2005, 36:1205.
7. Li S.L., Li P., Lin G., Zhou G.H., Ren Y.J., Que N.N. Acta Pharm. Sin. 1999, 34:842.
8. Zhang J.L., Wang H., Chen C., Pi H.F., Ruan H.L., Zhang P., Wu J.Z. Acta Pharm. Sin. 2009, 30:559.
9. Yun Y.G., Jeon B.H., Lee J.H., Lee S.K., Lee H.J., Jung K.H., Lee J., Jun C.D., Lee S.K., Kim E.C. Phytother. Res. 2008, 22:416.
10. Xu F.Z., Chen C., Zhou X.Q., Wang L.J., He G.M. Jin Ri Yao Xue 2008, 18:4.
11. Xu Y.J., Liu S.Y., Ding G.L., Huang E.X. Zhong Cheng Yao 1995, 17:11.
12. Zhao X., Liu Y., Chen Z.N. Chin. Tradit. Herb. Drugs 2001, 32:116.
13. Ding K., Lin G., Ho Y.P., Chang T.Y., Li P. J. Pharm. Sci. 1996, 85:1174.
14. Li S.L., Chan S.W., Li P., Lin G., Zhou G.H., Ren Y.J., Chiu F.C. J. Chromatogr. A 1999, 859:183.
15. Li S.L., Lin G., Chan S.W., Li P. J. Chromatogr. A 2001, 909:207.
16. Lin G., Li P., Li S.L., Chan S.W. J. Chromatogr. A 2001, 935:321.
17. Yu Y., Zhu Y.E. Chin. Pharm. J. 2006, 41:1026.
18. Zhou J.L., Li P., Li H.J., Jiang Y., Ren M.T., Liu Y. J. Chromatogr. A 2008, 1177:126.
19. Zhang Q.L., Wang A.Q., Song J., Li J.L., Cao J.R., Zhao J.H., Tang Z.X., Wu Z.Z. Chin. Pharm. J. 2000, 35:688.
20. Xin G.Z., Zhou J.L., Qi L.W., Li C.Y., Liu P., Li H.J., Wen X.D., Li P. J. Chromatogr. B 2010, 878:435.
21. Guidance of Industry: Bioanalytical Method Validation, US Department of Health and Human Services, Food and Drug Administration, CDER, Rockville, USA, 2001.