Functional herbal food ingredients used in type 2 diabetes mellitus

Pharmacognosy Reviews

Volumn 6, Issue 11, 2012, Pages 37-45

  Perera, Pathirage Kamal ^a   Li, Yunman ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Anti diabetic; functional herbal food; type 2 diabetes mellitus

Indexed keywords

AEGLE MARMELOS EXTRACT; ALLICIN; ALLOXAN; ARTOCARPUS HETEROPHYLLUS; DIALLYL TRISULFIDE; GANODERMA LUCIDUM EXTRACT; GARLIC EXTRACT; GLIBENCLAMIDE; GUAVA EXTRACT; HERBACEOUS AGENT; INSULIN; MANGIFERA INDICA EXTRACT; MOMORDICA CHARANTIA EXTRACT; MURRAYA KOENIGII EXTRACT; NELUMBO NUCIFERA EXTRACT; ONION EXTRACT; POMEGRANATE EXTRACT; PRUNELLA VULGARIS EXTRACT; SAPOGENIN; SITOSTEROL; STEVIA REBAUDINA; STEVIOSIDE; TANNIN; TOLBUTAMIDE; TRIGONELLA FOENUM GRAECUM EXTRACT; UNCLASSIFIED DRUG;

AEGLE MARMELOS; ALTERNATIVE MEDICINE; ARTERIOSCLEROSIS; CHINA; DIABETIC NEPHROPATHY; DISEASE COURSE; FENUGREEK; FUNCTIONAL FOOD; GARLIC; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE TOLERANCE TEST; GUAVA; HEART INFARCTION; HEARTBURN; HUMAN; HYPERGLYCEMIA; IMMOBILIZATION STRESS; INFECTION; INSULIN RESISTANCE; KETOACIDOSIS; LIPID PEROXIDATION; MANGO; MOMORDICA CHARANTIA; MURRAYA KOENIGII; NELUMBO NUCIFERA; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; ONION; PANCREAS ISLET BETA CELL; POLYDIPSIA; POLYURIA; POMEGRANATE; REVIEW; STRESS; TEA;

EID: 84862080109     PISSN: 09737847     EISSN: 09762787     Source Type: Journal    
DOI: 10.4103/0973-7847.95863     Document Type: Review

References (117)

1. IDF (2006). The Diabetes Atlas. Available from: http://www. eatlas.idf.org/media/.
2. De Groot M, Anderson R, Freedland KE, Clouse RE, Lustman PJ. Association of depression and diabetes complications: A meta-analysis. Psychosom Med 2001;63:619-30.
3. Jacobson AM. Impact of improved glycemic control on quality of life in patients with diabetes. Endocr Pract 2004;10:502-8.
4. Tahrani AA, Piya MK, Kennedy A, Barnett AH. Glycaemic control in type 2 diabetes: Targets and new therapies. Pharmacol Ther 2010;125:328-61.
5. Kahn SE, Haffner SM, Heise MA, Herman WH, Holman RR, Jones NP, et al. Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy. N Engl J Med 2006;355:2427-43.
6. Del PS, Bianchi C, Marchetti P. Beta-cell function and anti-diabetic pharmacotherapy. Diabetes Metab Res Rev 2007;23:518-27.
7. Groop LC, Tuomi T. Non-insulin dependent diabetes mellitus a collision between the thrifty gene and an affluent society. Ann Med 1997;2:937-53.
8. Facchini FS, Hua N, Abbasi F, Reaven GM. Insulin resistance as a predictor of age related diseases. J Clin Endocrinol Metab 2001;86:3574-8.
9. Stumvoll M, Goldstein BJ, van Haeften TW. Type 2 diabetes: Principles of pathogenesis and therapy. Lancet 2005;365:1333-46.
10. Kuzuya T, Nakagawa S, Satoh J, Kanazawa Y, Iwamoto Y, Kobayashi M, et al. Report of the Committee on the classi.cation and diagnostic criteria of diabetes mellitus. Diabetes Res Clin Pract 2002;55:65-85.
11. Gill GV, Redmond S, Garratt F, Paisey R. Diabetes and alternative medicine: Cause for concern. Diabetic Med 1994;11:210-3.
12. Christopoulou-Aletra H, Papavramidou N. 'Diabetes' as described by Byzantine writers from the fourth to the ninth century AD: The GraecoRoman in.uence. Diabetologia 2008;51:892-6.
13. Ahmed AM. History of diabetes mellitus. Saudi Med J 2002;23:373-8.
14. Maggie BC. Traditional Chinese medicine in the treatment of diabetes. Diabetes Spectrum 2001;14:154-9.
15. Liu JP, Zhang M, Wang WY, Grimsgaard S. Chinese herbal medicines for type 2 diabetes mellitus. Cochrane Database Syst Rev 2004;3:CD003642.
16. Jun Y, Hanjie Z, Jianping Y. Traditional Chinese medicine in treatment of metabolic syndrome. Endocr Metab Immune Disord Drug Targets 2008;8:99-111.
17. Gu Y, Zhang Y, Shi X, Li X, Hong J, Chen J, et al. Effect of traditional Chinese medicine berberine on type 2 diabetes based on comprehensive metabonomics Talanta 2010;81:766-72.
18. Rezabek KM. Medical nutrition therapy in type 2 diabetes. Nurs Clin North Am 2001;36:203-16.
19. Cheung BM. The Cardiovascular Continuum in Asia-A New Paradigm for the Metabolic Syndrome. J Cardiovasc Pharmacol 2005;46:125-9.
20. Vuksan V, Sievenpipera LJ. Herbal remedies in the management of diabetes: Lessons learned from the study of ginseng. Nutr Metab Cardiovasc Dis 2005;15:149-60.
21. Cheng JT. Review: Drug therapy in Chinese traditional medicine. J Clin Pharmacol 2000;40:445-50.
22. Swinbanks D, O'Brien J. Japan explores the boundary between food and medicine. Nature 1993;364:180.
23. Toma MM, Pokrotnieks J. Probiotics as functional food: Microbiological and medical aspects Acta Universitatis Latviensis 2006;710:117-29.
24. López-Varela S, Gonzalez-Gross M, Marcos A. Functional foods and the immune system: A review. Eur J Clin Nutr 2002;56:S29.
25. Roberfroid MB. What is beneficial for health? The concept of functional food. Food Chem Toxicol 1999;37:1034-41.
26. Duke JA, Ayensu ES. Medicinal Plants of China. Algonac : Reference Publications Inc.; 1985
27. Jamison JR. Garlic (Allium sativum). In: Clinical Guide to Nutrition and Dietary Supplements in Disease Management. London: Churchill Livingstone; 2003.
28. Kasuga S, Ushijima M, Morihara N, Itakura Y, Nakata Y. Effect of aged garlic extract (AGE) on hyperglycemia induced by immobilization stress in mice. Nippon Yakurigaku Zasshi 1999;114:191-7.
29. Liu CT, Hse H, Lii CK, Chen PS, Sheen LY. Effects of garlic oiland diallyl trisulfide on glycemic control in diabetic rats. Eur J Pharmacol 2005;516:165-73.
30. Mathew PT, Augusti KT. Studies on the effect of allicin (diallyl disulphide-oxide) on alloxan diabetes I. Hypoglycaemic action and enhancement of serum insulin effect and glycogen synthesis. Indian J Biochem Biophys 1973;10:209-12.
31. Augusti KT, Sheela CG. Antiperoxide effect of S-allyl cysteine sulfoxide, a insulin secretagogue, in diabetic rats. Experientia 1996;52:115-20.
32. Jain RC, Vyas CR. Hypoglycemic action of onion and garlic. Am J Clin Nutr 1975;28:684-5.
33. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 2nd ed. Montvale, NJ: Medical Economics Company; 2000.
34. Rshaad B, Azaizeh H, Said O. Tradition and perspectives of Arab herbal medicine: A review. Evid Based Complement Alternat Med 2005;2:475-9.
35. Baldé NM, Youla A, Baldé MD, Kaké A, Diallo MM, Baldé MA, et al. Herbal medicine and treatment of diabetes in Africa: An example from Guinea. Diabetes Metab 2006;32:171-5.
36. Babu PS, Srinivasan K. In.uence of dietary capsaicin and onion on the metabolic abnormalities associated with streptozotocin induced diabetes mellitus. Mol Cell Biochem 1997;175:49-57.
37. Babu PS, Srinivasan K. Renal lesions in streptozotocin-induced diabetic rats maintained on onion and capsaicin containing diets. J Nutr Biochem 1999;10:477-83.
38. Augusti KT, Roy VC, Semple M. Effect of allyl propyl disul.de isolated from onion (Allium cepa) on glucose tolerance of alloxan diabetic rabbits. Experientia 1974;30:1119-20.
39. Sheela CG, Kumud K, Augusti KT. Antidiabetic effects of onion and garlic sulfoxide amino acids in rats. Planta Med 1995;61:356-7.
40. Kumari K, Mathew BC, Augusti KT. Antidiabetic and hypolipidemic effects of S-methyl cysteine sulfoxide isolated from Allium cepa Linn. Indian J Biochem Biophys 1995;32:49-54.
41. Khosla P, Gupta DD, Nagpal RK. Effect of Trigonella foenum graecum (Fenugreek) on blood glucose in normal and diabetic rats. Indian J Physiol Pharmacol 1995;2:173-4.
42. Puri D, Prabhu KM, Murthy PS. Hypocholesterolemic effect of the hypoglycemic principle of fenugreek (Trigonella foenum graecum) seeds. Indian J Clin Biochem 1995;9:13-6.
43. Puri D, Prabhu KM, Murthy PS. Mechanism of action of a hypoglycemic principle isolated from fenugreek seeds. Indian J Physiol Pharmacol 2002;4:457-62.
44. Gupta A, Gupta R, Lal B. Effect of Trigonella foenum-graecum (fenugreek) seeds on glycaemic control and insulin resistance in type 2 diabetes mellitus: A double blind placebo controlled study. J Assoc Physicians India 2001;49:1057-61.
45. Vats V, Grover JK, Rathi SS. Evaluation of anti-hyperglycemic and hypoglycemic effect of Trigonella foenum-graecum Linn, Ocimum sanctum Linn and Pterocarpus marsupium Linn in normal and allox- anized diabetic rats. J Ethnopharmacol 2002;79:95-100.
46. Petit PR, Sauvaire YD, Hillaire-Buys DM, Leconte OM, Baissac YG, Ponsin GR, et al. Steroid saponins from fenugreek seeds extraction, puri.cation, and pharmacological investigation on feeding behavior and plasma cholesterol. Steroids 1995;60:674-80.
47. Ali L, Kalam A, Khan A, Hassan Z, Mosihuzzaman M, Nahar N, et al. Characterization of the hypoglycemic effects of Trigonella foenum-graecum seed. Planta Medica 1995;61:358-60.
48. Sauvaire Y, Petit P, Broca C, Manteghetti M, Baissac Y, Alvarez, JF, et al. 4-Hydroxyisoleucine: A novel amino acid potentiator of insulin secretion. Diabetes 1998;47:206-10.
49. Raghuram TC, Sharma RD, Sivakumar B, Sahay K. Effect of fenugreek seeds on intravenous glucose disposition in non-insulin dependent diabetic patients. Phytotherapy Res 1994;8:83-6.
50. Jimenez-Escrig A, Rincon M, Pulido R, Saura-Calixo F. Guava fruit (Psidium guajava L.) as a new source of antioxidant dietary fiber. J Agric Food Chem 2001;49:5489-93.
51. Mishra K, Seshadri TR. Chemical components of the fruits of Psidium guajava. Phytochemistry 1967;7:641-5.
52. Adsule RN, Kadam SS. In: Handbook of fruit science and technology. Production, composition storage, and processing. New York: M. Dekker; 1995.
53. Rai PK, Singh SK, Kesari AN, Watal G. Glycaemic evaluation of Psidium guajava in rats. Indian J Med Res 2007;126:224-7.
54. Rai PK, Rai NK, Rai AK, Watal G. Role of LIBS in elemental analysis of P. guajava responsible for glycemic potential. Instrum Sci Tech 2007;35:507-22.
55. Maryuma Y, Matsuda H, Matsuda R, Kubo M, Hatano T, Okuda T. Study on Psidium guajava L. (I). Antidiabetic effect and effective components of the leaf of Psidium guajava L. (Part I). Shoyakugaku Zasshi 1985;39:261-9.
56. Mukherjee PK, Saha K, Das J, Pal M, Saha BP. Studies on the anti-inflammatory activity of rhizomes of Nelumbo nucifera. Planta Med 1997;63:367-9.
57. Mukherjee PK, Saha K, Saha BP. Effect of Nelumbo nucifera rhizome extract on blood sugar level in rats. J Ethnopharmacol 1997;58:207-13.
58. Gao X, Dang Y. Traditional Chinese Medical Beauty Care. Peking: China Science and Technology Press; 2000.
59. Liu C, Tseng A. Chinese Herbal Medicine. Boca.Raton: CRC Press, LLC; 2005.
60. Zhou T, Luo D, Li X, Luo Y. Hypoglycemic and hypolipidemic effects of flavonoids from lotus (Nelumbo nucifera Gaertn) leaf in diabetic mice. Journal of Medicinal Plants Research 2009;3:290-3.
61. Jinmin S, Zhi Y. TLC-scanning determination of liensinine in lotus plumule. Chin J Hosp Pharm 1993;1:8-10.
62. Gregersen S, Jeppesen PB, Holst JJ, Hermansen K. Antihyperglycemic effects of stevioside in type 2 diabetic subjects. Metab Clin Exp 2004;53:73-6.
63. White JR Jr, Kramer J, Campbell RK, Bernstein R. Oral use of a topical preparation containing an extract of Stevia rebaudiana and the chrysanthemum .ower in the management of hyperglycemia. Diabetes Care 1994;17:940.
64. Jeppesen, PB, Gregersen S, Alstrup KK, Hermansen K. Stevioside induces antihyperglycaemic, insulinotropic and glucagonostatic effects in vivo: Studies in the diabetic Goto- Kakizaki (GK) rats. Phytomedicine 2002;9:9-14.
65. Liu BL, Zhu DN, Wang G. The anti-hyperglycemic effect of ethanol extract of Prunella vulgaris L. to mice. J. China Pharm Univ 1995;26:44-6.
66. Xu SL, Hou XJ, Wu AP. Pharmacological studies on blood sugarlowering activity of the active principle of common selfheal. Chin Tradit Herb Drugs 1989;20:358-60.
67. Kajima H, Ogura H. Triterpenoids from Prunella vugaris. Phytochemistry 1986;3:729-33.
68. Kajima H, Tominga H, Sato S. Pentacyclic tritepenoids from Prunella vulgaris. Phytochemistry 1987;4:1107-11.
69. Kajima H, Tominga H, Sato S. Two novel hexcyclic triterpenoids from Prunella vulgaris. Phtochemistry 1988;9:2921-5.
70. Dmitruk SI, Dmitruk SE, Berezovskaya TP. Flavonoids of Prunella vulgaris. Khim Prir Soedin 1987;3:449-50.
71. Natherova L, Rezacova A. Pharmacognostic studies of 3 species of the genus Prunella L. Acta Fac Pharm Univ Comeniana 1972;21:33-61.
72. Tabba HD, Chang RS, Smiths K. Isolation, purification and characterization of Prunellin: An anti-HIV component from aqueous extracts of Prunella vurgaris. Antiviral Res 1989;11:263-73.
73. Chang S, Buswell JA. Mushroom nutriceuticals. World J Microbiol Biotechnol 1996;12:473-6.
74. Kimura M, Diwan PV, Yanagi S, Kon-no Y, Nojima H, Kimura I. Potentiating effects of β-eudesmol-related cyclohexylidene derivatives on succinylcholine-induced neuromuscular block in isolated phrenic nerve-diaphragm muscles of normal and alloxan-diabetic mice. Biol Pharm Bull 1995;18:407-10.
75. Zhang LH, Xiao PG. Effect of the extract of ganoderma lucidum spores to experimental diabetes mellitus. Chin Tradit Herb Drugs 1993;24:246-7, 272.
76. Hikino H, Mizuno T, Oshima Y, Konno C. Isolation and hypoglycemic activity of Morans A. A glycoprotein of Morus alba root barks. Planta Med 1985;51:159-60.
77. Hikino H, Konno C, Mirin Y, Hayashi T. Isolation and hypoglycemic activity of ganoderans A and B. Glycans of Ganoderma lucidum fruit bodies. Planta Med 1985;51:339-40.
78. Jurenka JS. Therapeutic applications of pomegranate (Punica granatum L.): A review. Altern Med Rev 2008;13:128-44.
79. Jafri MA, Aslam M, Javed K, Singh S. Effect of Punica granatum Linn. (.owers) on blood glucose level in normal and alloxan induced diabetic rats. J Ethnopharmacol 2000;70:309-14.
80. Das AK, Mandal SC, Banerjee SK, Sinha S, Saha BP, Pal M. Studies on the hypoglycaemic activity of Punica granatum seed in streptozotocin induced diabetic rats. Phytother Res 2001;15:628-9.
81. Hao ZQ, Hang BQ, Wang Y. The anti-hyperglycemic effect of water decoction of Dioscorea opposita Thunb. To experimental diabetic mice. J China Pharm Univ 1991;22:158-60.
82. Huiqi S, Mingjing L, Aixin S, Xiuhua L. RP -HPLC Determination of Diosgenin in Dioscorea opposite Thunb. and D. alata L. Chinese Journal of Pharmaceutical Analysis 2004;05:1-4.
83. Raman A, Lau C. Anti-diabetic properties and phytochemistry of Momordica charantia L. (Cucurbitaceae). Phytomed 1996;2:349-62.
84. Miura T, Itoh C, Iwamoto N, Kato M, Kawai M, Park SR, et al. Hypoglycemic activity of the fruit of the Momordica charantia in type 2 diabetic mice. J Nutr Sci Vitaminol (Tokyo) 2001;47:340-4.
85. Fan YL, Cui FD. Comparative studies on hypoglycemic activity of different sections of Momordica charantia L. J Shenyang Pharm Univ 2001;18:50-3.
86. Srivastava Y, Venkatakrishna-Bhatt H, Verma Y, Venkaiah K, Raval BH. Antidiabetic and adaptogenic properties of Momordica charantia extract: An experimental and clinical evaluation. Phytother Res1993;7:285-9.
87. Ahmed I, Lakhani MS, Gillett M, John A, Raza H. Hypotriglyceridemic and hypocholesterolemic effects of anti-diabetic Momordica charantia (karela) fruit extract in streptozotocin-induced diabetic rats. Diabetes Res Clin Pract 2001;51:155-61.
88. Ooi CP, Yassin Z, Hamid TA. Momordica charantia for type 2 diabetes mellitus. Cochrane Database Syst Rev 2010;2:CD007845.
89. Wang, F, Zhang PP, Yu XF. A clinical observation of type 2 diabetes treated by saponins from Momordica charantia L. Pract Clin J Integrated Tradit Chin West Med 1991;4:721.
90. Zhang, PP, Wang F, Xue AQ. Experimental study on antihyperglycemic effect of "Kuguasu". Jiangsu J Chin Tradit Med 1992;13:30-1.
91. Arulselvan P, Senthilkumar GP, Sathish Kumar D, Subramanian S. Anti-diabetic effect of Murraya koenigii leaves on streptozotocin induced diabetic rats. Pharmazie 2006;61:874-7.
92. Arulselvan P, Subramanian SP. Beneficial effects of Murraya koenigii leaves on antioxidant defense system and ultra structural changes of pancreatic beta-cells in experimental diabetes in rats. Chem Biol Interact 2007;165:155-64.
93. Kesari AN, Gupta RK, Watal G. Hypoglycemic effects of Murraya koenigii on normal and alloxan-diabetic rabbits. J Ethnopharmacol 2005;97:247-51.
94. Nayak A, Manda S, Banerji A, Banerji J. Review on chemistry and pharmacology of Murraya koenigii Spreng (Rutaceae). J Chem Pharm Res 2010;2:286-99.
95. Tachibana Y, Kikuzaki H, Lajis NH, Nakatani N. J Agric Food Chem 2001;49:5589-94.
96. Narasimhan NS, Paradkar MV, Chitguppi VP, Kelkar SL. Indian J Chem 1975;13:993-9.
97. Reisch J, Goj O, Wickramasinghe A, Herath HM, Henkel G. Phytochem 1992;31:2877-9.
98. Prakash O, Kumar R, Mishra A, Gupta R. Artocarpus heterophyllus (Jackfruit): An overview. Phcog Rev 2009;3:353-8.
99. Jayaweera DM. Medicinal plants used in Ceylon 4-89. Part 11. Sri Lanka, Colombo: National Science Council; 1982.
100. Fernando MR, Wickramasinghe SM, Thabrew MI, Ariyaratne PL, Karunanayake EH. J Ethnopharmacol 1991;31:277-82.
101. Chackrewarthy S, Thabrew MI, Weerasuriya M, Jayasekera S. Evaluation of the hypoglycemic and hypolipidemic effects of an ethylacetate fraction of Artocarpus heterophyllus (jak) leaves in streptozotocin-induced diabetic rats. Phcog Mag 2010;6:186-90.
102. Prakash O, Kumar R, Mishra A, Gupta R. Artocarpus heterophyllus (Jackfruit): An overview. Phcog Rev 2009;3:353-8
103. Sathyavathi GV, Gupta AK, Tandon N. Medicinal plants of India. New Delhi, India: Indian Council of Medical Research; 1987.
104. Umezawa H, Aoyagi H, Ogawa K. Diprotein A and B, inhibitors of Dipeptidyl amino peptidase IV, produced by Bacteria. J Antibiot 1984;26:422-5.
105. Muruganandan S, Gupta S, Kataria M, Lal J, Gupta PK. Mangiferin protects the streptozotocin-induced oxidative damage to cardiac and renal tissues in rats. Toxicol 2002;176:165-73.
106. Miura T, Ichiki H, Iwamoto N, Kato M, Kubo M, Sasaki H, et al. Antidiabetic activity of the rhizome of Anemarrhena asphodloides and active components, mangiferin and its glucoside. Biol Pharm Bull 2001;24:1009-11.
107. Miura T, Iwamoto N, Kato M, Ichiki H, Kubo M, Komatsu Y, et al. The suppressive effect of mangiferin with exercise on blood lipids in type 2 diabetes. Biol Pharm Bull 2001;24:1091-2.
108. Hooker JD. The flora of British India. Vol. 1. Reeve, United Kingdom: Reeve and Co. ; 1975. p. 516-7
109. Islam R, Hossain M, Karim MR, Joarder OI. Regeneration of Aegle marmelos (L.) Corr., plantlets in vitro from callus cultures of embryonic tissues. Curr Sci 1995;69:494-5.
110. Ponnachan PT, Paulose CS, Panikar KR. Effect of the leaf extract of Aegle marmelos (L.) Corr. in diabetic rats. Indian J Exp Biol 1993;31:345-7.
111. Kamalakkannan N, Prince PS. The effect of Aegle marmelos fruit extract in streptozotocin diabetes: A histopathological study. J Herb Pharmacother 2005;5:87-96.
112. Seema PV, Sudha B, Padayatti SP, Abraham A, Raghu KG, Paulose CS. Kinetic studies of purified malate dehydrogenase in liver of streptozotozin - diabetic rats and the effect of leaf extract of Aegle marmelos (L.) Corr Indian J Exp Biol 1996;34:600-2.
113. Shnkar TN, Shanta NV, Ramesh HP, Murthy IA, Murthy VS. Toxicity Studies on Turmeric (Cuecuma longa): Acute Toxicity studies in rats, Guineapigsand Monkeys. Ind J Exp Biol 1980;18:73-5.
114. Eshrat MH, Hussain A. Hypoglycemic, hypolipidemic andantioxidant properties of combination of curcumin from Curcuma longa. Lnn, and partially purified product from Abroma augusta, Linn in streptozotocin induced diabetes. Indian J Clin Biochem 2002;17:33-43.
115. Tank R, Sharma N, Sharma, I, Dixit, VP. Anti-diabetic activity if C.longa in alloxan Induced diabetic rats . Indian drugs 1989;27:587-9.
116. Groop LC, Tuomi T. Non-insulin dependent diabetes mellitus a collision between the thrifty gene and an affluent society. Ann Med 1997;2:937-53.
117. Savoca M, Miller C. Food selection and eating patterns: Themes found among people with type 2 diabetes mellitus. J Nutr Educ Behav 2001; 33:224-233