Isocorydine inhibits cell proliferation in hepatocellular carcinoma cell lines by inducing G2/M cell cycle arrest and apoptosis

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Sun, Hefen ^a   Hou, Helei ^a   Lu, Ping ^a   Zhang, Lixing ^a   Zhao, Fangyu ^a   Ge, Chao ^a   Wang, Tingpu ^b   Yao, Ming ^a   Li, Jinjun ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b TIANSHUI NORMAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CD133 ANTIGEN; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; ISOCORYDINE; PROTEIN CDC25C; PROTEIN TYROSINE PHOSPHATASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; APORPHINE DERIVATIVE; PLANT EXTRACT; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL COUNT; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; M PHASE CELL CYCLE CHECKPOINT; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; CELL CYCLE CHECKPOINT; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECT; FLOW CYTOMETRY; ISOLATION AND PURIFICATION; LIVER TUMOR; METABOLISM; METHODOLOGY; PAPAVERACEAE; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYTOTHERAPY; RNA INTERFERENCE; TUMOR CELL LINE; WESTERN BLOTTING;

PAPAVERACEAE;

APOPTOSIS; APORPHINES; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; FLOW CYTOMETRY; HUMANS; LIVER NEOPLASMS; PAPAVERACEAE; PHOSPHORYLATION; PHYTOTHERAPY; PLANT EXTRACTS; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; TETRAZOLIUM SALTS; THIAZOLES;

EID: 84862062345     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036808     Document Type: Article

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