메뉴 건너뛰기




Volumn 188, Issue 11, 2012, Pages 5257-5266

Chronic spinal cord injury impairs primary antibody responses but spares existing humoral immunity in mice

Author keywords

[No Author keywords available]

Indexed keywords

THYMUS DEPENDENT ANTIGEN; THYMUS INDEPENDENT ANTIGEN; THYMUS INDEPENDENT ANTIGEN TYPE 2; UNCLASSIFIED DRUG;

EID: 84862060040     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1101934     Document Type: Article
Times cited : (28)

References (51)
  • 1
    • 27944503933 scopus 로고    scopus 로고
    • Central nervous system injury-induced immune deficiency syndrome
    • DOI 10.1038/nrn1765, PII N1765
    • Meisel, C., J. M. Schwab, K. Prass, A. Meisel, and U. Dirnagl. 2005. Central nervous system injury-induced immune deficiency syndrome. Nat. Rev. Neurosci. 6: 775-786. (Pubitemid 41679240)
    • (2005) Nature Reviews Neuroscience , vol.6 , Issue.10 , pp. 775-786
    • Meisel, C.1    Schwab, J.M.2    Prass, K.3    Meisel, A.4    Dirnagl, U.5
  • 4
    • 0033136309 scopus 로고    scopus 로고
    • Suppression of antigen-specific Th2 cell-dependent IgM and IgG1 production following norepinephrine depletion in vivo
    • Kohm, A. P., and V. M. Sanders. 1999. Suppression of antigen-specific Th2 cell-dependent IgM and IgG1 production following norepinephrine depletion in vivo. J. Immunol. 162: 5299-5308. (Pubitemid 29307136)
    • (1999) Journal of Immunology , vol.162 , Issue.9 , pp. 5299-5308
    • Kohm, A.P.1    Sanders, V.M.2
  • 5
    • 34347258134 scopus 로고    scopus 로고
    • Autonomic innervation and regulation of the immune system (1987-2007)
    • DOI 10.1016/j.bbi.2007.03.008, PII S088915910700075X
    • Nance, D. M., and V. M. Sanders. 2007. Autonomic innervation and regulation of the immune system (1987-2007). Brain Behav. Immun. 21: 736-745. (Pubitemid 47002215)
    • (2007) Brain, Behavior, and Immunity , vol.21 , Issue.6 , pp. 736-745
    • Nance, D.M.1    Sanders, V.M.2
  • 6
    • 0037546954 scopus 로고    scopus 로고
    • 2-receptor stimulation
    • Podojil, J. R., and V. M. Sanders. 2003. Selective regulation of mature IgG1 transcription by CD86 and b2-adrenergic receptor stimulation. J. Immunol. 170: 5143-5151. (Pubitemid 36554746)
    • (2003) Journal of Immunology , vol.170 , Issue.10 , pp. 5143-5151
    • Podojil, J.R.1    Sanders, V.M.2
  • 7
    • 0023624629 scopus 로고
    • Noradrenergic sympathetic innervation of the spleen: II. Tyrosine hydroxylase (TH)-positive nerve terminals form synapticlike contacts on lymphocytes in the splenic white pulp
    • Felten, S. Y., and J. Olschowka. 1987. Noradrenergic sympathetic innervation of the spleen: II. Tyrosine hydroxylase (TH)-positive nerve terminals form synapticlike contacts on lymphocytes in the splenic white pulp. J. Neurosci. Res. 18: 37-48.
    • (1987) J. Neurosci. Res. , vol.18 , pp. 37-48
    • Felten, S.Y.1    Olschowka, J.2
  • 8
    • 0029840243 scopus 로고    scopus 로고
    • Noradrenergic and peptidergic innervation of the mouse femur bone marrow
    • Tabarowski, Z., K. Gibson-Berry, and S. Y. Felten. 1996. Noradrenergic and peptidergic innervation of the mouse femur bone marrow. Acta Histochem. 98: 453-457. (Pubitemid 26401003)
    • (1996) Acta Histochemica , vol.98 , Issue.4 , pp. 453-457
    • Tabarowski, Z.1    Gibson-Berry, K.2    Felten, S.Y.3
  • 9
    • 34548238147 scopus 로고    scopus 로고
    • Impaired antibody synthesis after spinal cord injury is level dependent and is due to sympathetic nervous system dysregulation
    • DOI 10.1016/j.expneurol.2007.05.019, PII S0014488607002178
    • Lucin, K. M., V. M. Sanders, T. B. Jones, W. B. Malarkey, and P. G. Popovich. 2007. Impaired antibody synthesis after spinal cord injury is level dependent and is due to sympathetic nervous system dysregulation. Exp. Neurol. 207: 75-84. (Pubitemid 47332484)
    • (2007) Experimental Neurology , vol.207 , Issue.1 , pp. 75-84
    • Lucin, K.M.1    Sanders, V.M.2    Jones, T.B.3    Malarkey, W.B.4    Popovich, P.G.5
  • 10
    • 77957761011 scopus 로고    scopus 로고
    • Impaired immune responses following spinal cord injury lead to reduced ability to control viral infection
    • Held, K. S., O. Steward, C. Blanc, and T. E. Lane. 2010. Impaired immune responses following spinal cord injury lead to reduced ability to control viral infection. Exp. Neurol. 226: 242-253.
    • (2010) Exp. Neurol. , vol.226 , pp. 242-253
    • Held, K.S.1    Steward, O.2    Blanc, C.3    Lane, T.E.4
  • 11
    • 0037271439 scopus 로고    scopus 로고
    • Physical size does not determine the unique histopathological response seen in the injured mouse spinal cord
    • Inman, D. M., and O. Steward. 2003. Physical size does not determine the unique histopathological response seen in the injured mouse spinal cord. J. Neurotrauma 20: 33-42. (Pubitemid 36176958)
    • (2003) Journal of Neurotrauma , vol.20 , Issue.1 , pp. 33-42
    • Inman, D.M.1    Steward, O.2
  • 12
    • 0028954663 scopus 로고
    • Corticosterone, adrenal and spleen weight in mice after tail bleeding, and its effect on nearby animals
    • Tuli, J. S., J. A. Smith, and D. B. Morton. 1995. Corticosterone, adrenal and spleen weight in mice after tail bleeding, and its effect on nearby animals. Lab. Anim. 29: 90-95.
    • (1995) Lab. Anim. , vol.29 , pp. 90-95
    • Tuli, J.S.1    Smith, J.A.2    Morton, D.B.3
  • 13
    • 0034028175 scopus 로고    scopus 로고
    • Cardiovascular consequences of loss of supraspinal control of the sympathetic nervous system after spinal cord injury
    • DOI 10.1053/mr.2000.3848
    • Teasell, R. W., J. M. Arnold, A. Krassioukov, and G. A. Delaney. 2000. Cardiovascular consequences of loss of supraspinal control of the sympathetic nervous system after spinal cord injury. Arch. Phys. Med. Rehabil. 81: 506-516. (Pubitemid 30192047)
    • (2000) Archives of Physical Medicine and Rehabilitation , vol.81 , Issue.4 , pp. 506-516
    • Teasell, R.W.1    Arnold, J.M.O.2    Krassioukov, A.3    Delaney, G.A.4
  • 14
    • 0035829144 scopus 로고    scopus 로고
    • Characterization of the central nervous system innervation of the rat spleen using viral transneuronal tracing
    • Cano, G., A. F. Sved, L. Rinaman, B. S. Rabin, and J. P. Card. 2001. Characterization of the central nervous system innervation of the rat spleen using viral transneuronal tracing. J. Comp. Neurol. 439: 1-18.
    • (2001) J. Comp. Neurol. , vol.439 , pp. 1-18
    • Cano, G.1    Sved, A.F.2    Rinaman, L.3    Rabin, B.S.4    Card, J.P.5
  • 15
    • 0037163431 scopus 로고    scopus 로고
    • Genetic influences on secondary degeneration and wound healing following spinal cord injury in various strains of mice
    • DOI 10.1002/cne.10340
    • Inman, D., L. Guth, and O. Steward. 2002. Genetic influences on secondary degeneration and wound healing following spinal cord injury in various strains of mice. J. Comp. Neurol. 451: 225-235. (Pubitemid 34969082)
    • (2002) Journal of Comparative Neurology , vol.451 , Issue.3 , pp. 225-235
    • Inman, D.1    Guth, L.2    Steward, O.3
  • 16
    • 68949215875 scopus 로고    scopus 로고
    • Stress hormones collaborate to induce lymphocyte apoptosis after high level spinal cord injury
    • Lucin, K. M., V. M. Sanders, and P. G. Popovich. 2009. Stress hormones collaborate to induce lymphocyte apoptosis after high level spinal cord injury. J. Neurochem. 110: 1409-1421.
    • (2009) J. Neurochem. , vol.110 , pp. 1409-1421
    • Lucin, K.M.1    Sanders, V.M.2    Popovich, P.G.3
  • 17
    • 0035892228 scopus 로고    scopus 로고
    • Resolution of three nonproliferate immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation
    • Allman, D., R. C. Lindsley, W. DeMuth, K. Rudd, S. A. Shinton, and R. R. Hardy. 2001. Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation. J. Immunol. 167: 6834-6840. (Pubitemid 33144175)
    • (2001) Journal of Immunology , vol.167 , Issue.12 , pp. 6834-6840
    • Allman, D.1    Lindsley, R.C.2    Demuth, W.3    Rudd, K.4    Shinton, S.A.5    Hardy, R.R.6
  • 18
    • 0942268734 scopus 로고    scopus 로고
    • Peripheral B-cell maturation: The intersection of selection and homeostasis
    • DOI 10.1111/j.0105-2896.2004.0099.x
    • Cancro, M. P. 2004. Peripheral B-cell maturation: the intersection of selection and homeostasis. Immunol. Rev. 197: 89-101. (Pubitemid 38142170)
    • (2004) Immunological Reviews , vol.197 , pp. 89-101
    • Cancro, M.P.1
  • 21
    • 0022931316 scopus 로고
    • Population dynamics of bone marrow B lymphocytes
    • Osmond, D. G. 1986. Population dynamics of bone marrow B lymphocytes. Immunol. Rev. 93: 103-124. (Pubitemid 17171501)
    • (1986) Immunological Reviews , vol.NO. 93 , pp. 103-124
    • Osmond, D.G.1
  • 22
    • 0027379716 scopus 로고
    • hi splenic B cells are an immature developmental intermediate in the production of long-lived marrow-derived B cells
    • hi splenic B cells are an immature developmental intermediate in the production of long-lived marrow-derived B cells. J. Immunol. 151: 4431-4444.
    • (1993) J. Immunol. , vol.151 , pp. 4431-4444
    • Allman, D.M.1    Ferguson, S.E.2    Lentz, V.M.3    Cancro, M.P.4
  • 23
    • 0031738699 scopus 로고    scopus 로고
    • Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity
    • DOI 10.1002/(SICI)1521-4141(199811)28:11<3738::AID-IMMU3738>3.0. CO;2-Q
    • Rolink, A. G., J. Andersson, and F. Melchers. 1998. Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity. Eur. J. Immunol. 28: 3738-3748. (Pubitemid 28510784)
    • (1998) European Journal of Immunology , vol.28 , Issue.11 , pp. 3738-3748
    • Rolink, A.G.1    Andersson, J.2    Melchers, F.3
  • 24
    • 33947239920 scopus 로고    scopus 로고
    • Generation of peripheral B cells occurs via two spatially and temporally distinct pathways
    • Lindsley, R. C., M. Thomas, B. Srivastava, and D. Allman. 2007. Generation of peripheral B cells occurs via two spatially and temporally distinct pathways. Blood 109: 2521-2528.
    • (2007) Blood , vol.109 , pp. 2521-2528
    • Lindsley, R.C.1    Thomas, M.2    Srivastava, B.3    Allman, D.4
  • 26
    • 0015693581 scopus 로고
    • Circulating T and B lymphocytes of the mouse, II: Lifespan
    • Sprent, J., and A. Basten. 1973. Circulating T and B lymphocytes of the mouse, II: Lifespan. Cell. Immunol. 7: 40-59.
    • (1973) Cell. Immunol. , vol.7 , pp. 40-59
    • Sprent, J.1    Basten, A.2
  • 27
    • 0025339171 scopus 로고
    • The bulk of the peripheral B-cell pool in mice is stable and not rapidly renewed from the bone marrow
    • Förster, I., and K. Rajewsky. 1990. The bulk of the peripheral B-cell pool in mice is stable and not rapidly renewed from the bone marrow. Proc. Natl. Acad. Sci. USA 87: 4781-4784.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 4781-4784
    • Förster, I.1    Rajewsky, K.2
  • 28
    • 0034686433 scopus 로고    scopus 로고
    • Immunization and infection change the number of recombination activating gene (RAG)-expressing B cells in the periphery by altering immature lymphocyte production
    • DOI 10.1084/jem.191.12.2113
    • Nagaoka, H., G. Gonzalez-Aseguinolaza, M. Tsuji, and M. C. Nussenzweig. 2000. Immunization and infection change the number of recombination activating gene (RAG)-expressing B cells in the periphery by altering immature lymphocyte production. J. Exp. Med. 191: 2113-2120. (Pubitemid 30416358)
    • (2000) Journal of Experimental Medicine , vol.191 , Issue.12 , pp. 2113-2120
    • Nagaoka, H.1    Gonzalez-Aseguinolaza, G.2    Tsuji, M.3    Nussenzweig, M.C.4
  • 29
    • 22344437262 scopus 로고    scopus 로고
    • Inflammation and the reciprocal production of granulocytes and lymphocytes in bone marrow
    • DOI 10.1084/jem.20041419
    • Ueda, Y., M. Kondo, and G. Kelsoe. 2005. Inflammation and the reciprocal production of granulocytes and lymphocytes in bone marrow. J. Exp. Med. 201: 1771-1780. (Pubitemid 41002896)
    • (2005) Journal of Experimental Medicine , vol.201 , Issue.11 , pp. 1771-1780
    • Ueda, Y.1    Kondo, M.2    Kelsoe, G.3
  • 30
    • 0022233683 scopus 로고
    • Differences in antibody repertoires for (4-hydroxy-3-nitrophenyl)acetyl (NP) in splenic vs immature bone marrow precursor cells
    • Riley, R. L., and N. R. Klinman. 1985. Differences in antibody repertoires for (4- hydroxy-3-nitrophenyl)acetyl (NP) in splenic vs immature bone marrow precursor cells. J. Immunol. 135: 3050-3055. (Pubitemid 16250557)
    • (1985) Journal of Immunology , vol.135 , Issue.5 , pp. 3050-3055
    • Riley, R.L.1    Klinman, N.R.2
  • 31
    • 0034232062 scopus 로고    scopus 로고
    • Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response
    • Guinamard, R., M. Okigaki, J. Schlessinger, and J. V. Ravetch. 2000. Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response. Nat. Immunol. 1: 31-36.
    • (2000) Nat. Immunol. , vol.1 , pp. 31-36
    • Guinamard, R.1    Okigaki, M.2    Schlessinger, J.3    Ravetch, J.V.4
  • 32
    • 0003381544 scopus 로고    scopus 로고
    • T-independent type 2 antigens induce B cell proliferation in multiple splenic sites, but exponential growth is confined to extrafollicular foci
    • García de Vinuesa, C., P. O'Leary, D. M. Sze, K. M. Toellner, and I. C. MacLennan. 1999. T-independent type 2 antigens induce B cell proliferation in multiple splenic sites, but exponential growth is confined to extrafollicular foci. Eur. J. Immunol. 29: 1314-1323. (Pubitemid 29164178)
    • (1999) European Journal of Immunology , vol.29 , Issue.4 , pp. 1314-1323
    • Garcia, D.V.C.1    O'Leary, P.2    Sze, D.M.-Y.3    Toellner, K.-M.4    MacLennan, I.C.M.5
  • 33
    • 0032536872 scopus 로고    scopus 로고
    • In situ studies of the primary immune response to (4-hydroxy-3- nitrophenyl)acetyl. v. affinity maturation develops in two stages of clonal selection
    • DOI 10.1084/jem.187.6.885
    • Takahashi, Y., P. R. Dutta, D. M. Cerasoli, and G. Kelsoe. 1998. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl, V: Affinity maturation develops in two stages of clonal selection. J. Exp. Med. 187: 885-895. (Pubitemid 28141662)
    • (1998) Journal of Experimental Medicine , vol.187 , Issue.6 , pp. 885-895
    • Takahashi, Y.1    Dutta, P.R.2    Cerasoli, D.M.3    Kelsoe, G.4
  • 34
    • 0031859661 scopus 로고    scopus 로고
    • Germinal centers: Form and function
    • DOI 10.1016/S0952-7915(98)80161-1
    • Tarlinton, D. 1998. Germinal centers: form and function. Curr. Opin. Immunol. 10: 245-251. (Pubitemid 28286949)
    • (1998) Current Opinion in Immunology , vol.10 , Issue.3 , pp. 245-251
    • Tarlinton, D.1
  • 35
    • 0019971005 scopus 로고
    • Germinal centre B cells: Antigen specificity and changes in heavy chain class expression
    • DOI 10.1038/298377a0
    • Kraal, G., I. L. Weissman, and E. C. Butcher. 1982. Germinal centre B cells: antigen specificity and changes in heavy chain class expression. Nature 298: 377-379. (Pubitemid 12044292)
    • (1982) Nature , vol.298 , Issue.5872 , pp. 377-379
    • Kraal, G.1    Weissman, I.L.2    Butcher, E.C.3
  • 36
    • 0029062080 scopus 로고
    • Regulation of germinal center B cell differentiation: Role of the human APO-1/ Fas (CD95) molecule
    • Lagresle, C., C. Bella, P. T. Daniel, P. H. Krammer, and T. Defrance. 1995. Regulation of germinal center B cell differentiation: role of the human APO-1/ Fas (CD95) molecule. J. Immunol. 154: 5746-5756.
    • (1995) J. Immunol. , vol.154 , pp. 5746-5756
    • Lagresle, C.1    Bella, C.2    Daniel, P.T.3    Krammer, P.H.4    Defrance, T.5
  • 37
    • 0018836189 scopus 로고
    • Peanut lectin binding properties of germinal centres of mouse lymphoid tisse
    • Rose, M. L., M. S. Birbeck, V. J. Wallis, J. A. Forrester, and A. J. Davies. 1980. Peanut lectin binding properties of germinal centres of mouse lymphoid tissue. Nature 284: 364-366. (Pubitemid 10122194)
    • (1980) Nature , vol.284 , Issue.5754 , pp. 364-366
    • Rose, M.L.1    Birbeck, M.S.C.2    Wallis, V.J.3
  • 38
    • 0018901792 scopus 로고
    • Memory B cells at successive stages of differentiation. Affinity maturation and the role of IgD receptors
    • Herzenberg, L. A., S. J. Black, T. Tokuhisa, and L. A. Herzenberg. 1980. Memory B cells at successive stages of differentiation: affinity maturation and the role of IgD receptors. J. Exp. Med. 151: 1071-1087. (Pubitemid 10111923)
    • (1980) Journal of Experimental Medicine , vol.151 , Issue.5 , pp. 1071-1087
    • Herzenberg, L.A.1    Black, S.J.2    Tokuhisa, T.3    Herzenberg, L.A.4
  • 40
    • 0025601012 scopus 로고
    • The repertoire of somatic antibody mutants accumulating in the memory compartment after primary immunization is restricted through affinity maturation and mirrors that expressed in the secondary response
    • Weiss, U., and K. Rajewsky. 1990. The repertoire of somatic antibody mutants accumulating in the memory compartment after primary immunization is restricted through affinity maturation and mirrors that expressed in the secondary response. J. Exp. Med. 172: 1681-1689.
    • (1990) J. Exp. Med. , vol.172 , pp. 1681-1689
    • Weiss, U.1    Rajewsky, K.2
  • 41
    • 4644233698 scopus 로고    scopus 로고
    • Preserved granulocyte formation and function, as well as bone marrow innervation, in subjects with complete spinal cord injury
    • DOI 10.1111/j.1365-2141.2004.05085.x
    • Iversen, P. O., A. Nicolaysen, N. Hjeltnes, A. Njå, and H. B. Benestad. 2004. Preserved granulocyte formation and function, as well as bone marrow innervation, in subjects with complete spinal cord injury. Br. J. Haematol. 126: 870-877. (Pubitemid 39273829)
    • (2004) British Journal of Haematology , vol.126 , Issue.6 , pp. 870-877
    • Iversen, P.O.1    Nicolaysen, A.2    Hjeltnes, N.3    Nja, A.4    Benestad, H.B.5
  • 43
    • 0347285361 scopus 로고    scopus 로고
    • Inflammation controls B lymphopoiesis by regulating chemokine CXCL12 expression
    • Ueda, Y., K. Yang, S. J. Foster, M. Kondo, and G. Kelsoe. 2004. Inflammation controls B lymphopoiesis by regulating chemokine CXCL12 expression. J. Exp. Med. 199: 47-58.
    • (2004) J. Exp. Med. , vol.199 , pp. 47-58
    • Ueda, Y.1    Yang, K.2    Foster, S.J.3    Kondo, M.4    Kelsoe, G.5
  • 44
    • 0023767076 scopus 로고
    • IL-1 inhibits B cell differentiation in long term bone marrow cultures
    • Dorshkind, K. 1988. IL-1 inhibits B cell differentiation in long term bone marrow cultures. J. Immunol. 141: 531-538.
    • (1988) J. Immunol. , vol.141 , pp. 531-538
    • Dorshkind, K.1
  • 45
    • 0031962665 scopus 로고    scopus 로고
    • Impairment of T and B cell development by treatment with a type I interferon
    • DOI 10.1084/jem.187.1.79
    • Lin, Q., C. Dong, and M. D. Cooper. 1998. Impairment of T and B cell development by treatment with a type I interferon. J. Exp. Med. 187: 79-87. (Pubitemid 28044822)
    • (1998) Journal of Experimental Medicine , vol.187 , Issue.1 , pp. 79-87
    • Lin, Q.1    Dong, C.2    Cooper, M.D.3
  • 46
    • 33845568271 scopus 로고    scopus 로고
    • Proinflammatory cytokine synthesis in the injured mouse spinal cord: Multiphasic expression pattern and identification of the cell types involved
    • DOI 10.1002/cne.21149
    • Pineau, I., and S. Lacroix. 2007. Proinflammatory cytokine synthesis in the injured mouse spinal cord: multiphasic expression pattern and identification of the cell types involved. J. Comp. Neurol. 500: 267-285. (Pubitemid 44937122)
    • (2007) Journal of Comparative Neurology , vol.500 , Issue.2 , pp. 267-285
    • Pineau, I.1    Lacroix, S.2
  • 47
    • 0035846593 scopus 로고    scopus 로고
    • Competition for BLyS-mediated signaling through Bcmd/BR3 regulates peripheral B lymphocyte numbers
    • DOI 10.1016/S0960-9822(01)00598-X
    • Harless, S. M., V. M. Lentz, A. P. Sah, B. L. Hsu, K. Clise-Dwyer, D. M. Hilbert, C. E. Hayes, and M. P. Cancro. 2001. Competition for BLyS-mediated signaling through Bcmd/BR3 regulates peripheral B lymphocyte numbers. Curr. Biol. 11: 1986-1989. (Pubitemid 33146427)
    • (2001) Current Biology , vol.11 , Issue.24 , pp. 1986-1989
    • Harless, S.M.1    Lentz, V.M.2    Sah, A.P.3    Hsu, B.L.4    Clise-Dwyer, K.5    Hilbert, D.M.6    Hayes, C.E.7    Cancro, M.P.8
  • 48
    • 0025758478 scopus 로고
    • Phenotypic and genetic characterization of a unique B lymphocyte deficiency in strain A/WySnJ mice
    • Miller, D. J., and C. E. Hayes. 1991. Phenotypic and genetic characterization of a unique B lymphocyte deficiency in strain A/WySnJ mice. Eur. J. Immunol. 21: 1123-1130.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 1123-1130
    • Miller, D.J.1    Hayes, C.E.2
  • 50
    • 0035013708 scopus 로고    scopus 로고
    • Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens
    • DOI 10.1016/S1074-7613(01)00129-7
    • Martin, F., A. M. Oliver, and J. F. Kearney. 2001. Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens. Immunity 14: 617-629. (Pubitemid 32520872)
    • (2001) Immunity , vol.14 , Issue.5 , pp. 617-629
    • Martin, F.1    Oliver, A.M.2    Kearney, J.F.3
  • 51
    • 0034813687 scopus 로고    scopus 로고
    • Novel vaccine strategies to T-independent antigens
    • DOI 10.1016/S0167-7012(01)00290-1, PII S0167701201002901
    • Lesinski, G. B., and M. A. Westerink. 2001. Novel vaccine strategies to T-independent antigens. J. Microbiol. Methods 47: 135-149. (Pubitemid 32910271)
    • (2001) Journal of Microbiological Methods , vol.47 , Issue.2 , pp. 135-149
    • Lesinski, G.B.1    Westerink, M.A.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.