Neutralizing aspartate 83 modifies substrate translocation of Excitatory Amino Acid Transporter 3 (EAAT3) glutamate transporters

Journal of Biological Chemistry

Volumn 287, Issue 24, 2012, Pages 20016-20026

  Hotzy, Jasmin ^a   Machtens, Jan Philipp ^a   Fahlke, Christoph ^a,b  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b CENTER FOR SYSTEMS NEUROSCIENCE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE TRANSPORT; ANION CHANNELS; ASPARTATES; ASPARTIC ACIDS; EXCITATORY AMINO ACIDS; EXPERIMENTAL DATA; FLUORESCENCE INTENSITIES; GLIAL CELLS; GLUTAMATE TRANSPORTERS; INTRACELLULAR LOOP; POINT MUTATIONS; SYNAPTIC CLEFT; SYNAPTIC TRANSMISSION; TIGHTLY-COUPLED; TRANS-MEMBRANE DOMAINS; TRANSPORT CYCLE; VOLTAGE CLAMP;

ACTIVATION ANALYSIS; AMINO ACIDS; FLUORESCENCE; FLUOROPHORES; SODIUM; SUBSTRATES;

IONS;

ASPARTIC ACID; ASPARTIC ACID 83; EXCITATORY AMINO ACID TRANSPORTER 3; SODIUM ION; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CHANNEL GATING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; HUMAN; HYPERPOLARIZATION; ION CURRENT; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN TRANSPORT; SYNAPTIC TRANSMISSION; VOLTAGE CLAMP;

AMINO ACID SUBSTITUTION; ANIMALS; ASPARTIC ACID; EXCITATORY AMINO ACID TRANSPORTER 3; GLUTAMIC ACID; HUMANS; ION CHANNEL GATING; ION TRANSPORT; MODELS, BIOLOGICAL; MUTATION, MISSENSE; XENOPUS LAEVIS;

EID: 84862025150     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.344077     Document Type: Article

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