Polyhydroxylated fullerene C 60(OH) 44 suppresses intracellular lipid accumulation together with repression of intracellular superoxide anion radicals and subsequent PPARγ2 expression during spontaneous differentiation of OP9 preadipocytes into adipocytes

Molecular and Cellular Biochemistry

Volumn 366, Issue 1-2, 2012, Pages 191-200

  Saitoh, Yasukazu ^a   Mizuno, Hiromi ^a   Xiao, Li ^a,b   Hyoudou, Sayuri ^c   Kokubo, Ken ^d   Miwa, Nobuhiko ^a,e  

^a PREFECTURAL UNIVERSITY OF HIROSHIMA   (Japan)

^b NIPPON DENTAL UNIVERSITY   (Japan)

^c Vitamin C60 BioResearch Corporation   (Japan)

^d OSAKA UNIVERSITY   (Japan)

^e BUTSURYO COLLEGE OF OSAKA   (Japan)

Author keywords

Adipocytes; Differentiation; Fullerenol; Lipid accumulation; PPAR ; Reactive oxygen species

Indexed keywords

FAT DROPLET; FULLERENE DERIVATIVE; OXYGEN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; POLYHYDROXYLATED FULLERENE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; HORMONE RELEASE; INTRACELLULAR SPACE; LIPID ANALYSIS; LIPID COMPOSITION; LIPID STORAGE; MOUSE; NONHUMAN; OBESITY; OXIDATIVE STRESS; PROADIPOCYTE; PROTEIN EXPRESSION; THIN LAYER CHROMATOGRAPHY; UPREGULATION;

ADIPOCYTES; ANIMALS; ANTI-OBESITY AGENTS; CELL DIFFERENTIATION; CELL SURVIVAL; CHOLESTEROL; FULLERENES; INTRACELLULAR FLUID; LIPID METABOLISM; MICE; OLEIC ACID; PHOSPHOLIPIDS; PPAR GAMMA; STROMAL CELLS; SUPEROXIDES; TRIGLYCERIDES;

EID: 84862014813     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-012-1297-8     Document Type: Article

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