Expression in Drosophila of tandem amyloid β peptides provides insights into links between aggregation and neurotoxicity

Journal of Biological Chemistry

Volumn 287, Issue 24, 2012, Pages 20748-20754

  Speretta, Elena ^a   Jahn, Thomas R ^a   Tartaglia, Gian Gaetano ^a,c   Favrin, Giorgio ^a   Barros, Teresa P ^a   Imarisio, Sara ^a   Lomas, David A ^b   Luheshi, Leila M ^a   Crowther, Damian C ^a,b   Dobson, Christopher M ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITAT POMPEU FABRA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AGGREGATES; GLYCOPROTEINS; OLIGOMERS; TOXICITY;

AGGREGATION KINETICS; ALZHEIMER DISEASE; AMYLOID-BETA PEPTIDES; DROSOPHILA MELANOGASTER; EFFECTIVE CONCENTRATION; INSOLUBLE AGGREGATES; INTERMEDIATE STATE; KINETIC STABILITY;

PEPTIDES;

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42];

AMINO ACID COMPOSITION; AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; GENE LOCUS; GENOTYPE; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RETINA; SURVIVAL RATE; TRANSGENE;

DROSOPHILA MELANOGASTER;

EID: 84862003761     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.350124     Document Type: Article

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