Novel chimerical endolysins with broad antimicrobial activity against methicillin-resistant Staphylococcus aureus

Microbial Drug Resistance

Volumn 18, Issue 3, 2012, Pages 333-343

  Fernandes, Sofia ^a,b   Proença, Daniela ^a   Cantante, Cátia ^a   Silva, Filipa Antunes ^a   Leandro, Clara ^a   Lourenço, Sara ^a   Milheiriço, Catarina ^c   De Lencastre, Hermínia ^c,d   Cavaco Silva, Patrícia ^a,e   Pimentel, Madalena ^b   São José, Carlos ^b,f  

^a Technophage SA   (Portugal)

^b RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

^c INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

^d ROCKEFELLER UNIVERSITY   (United States)

^e INSTITUTO SUPERIOR DE CIÊNCIAS DA SAÚDE EGAS MONIZ   (Portugal)

^f INSTITUTO DE MEDICINA MOLECULAR JOÃO LOBO ANTUNES   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; CHIMERIC PROTEIN; ENTEROCOCCAL ENDOLYSIN 168 87; ENTEROCOCCAL ENDOLYSIN 170 87; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL CELL WALL; BACTERIOLYSIS; BACTERIOPHAGE; CHIMERA; CONTROLLED STUDY; ENTEROCOCCUS; ENZYME THERAPY; EPIDEMIC; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; SOLUBILITY;

AMIDOHYDROLASES; ANTI-BACTERIAL AGENTS; CELL WALL; CLONING, MOLECULAR; ENTEROCOCCUS FAECALIS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; PEPTIDOGLYCAN; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SOLUBILITY; STAPHYLOCOCCUS PHAGES; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL PROTEINS;

BACTERIA (MICROORGANISMS); METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; POSIBACTERIA; STAPHYLOCOCCUS AUREUS;

EID: 84862001592     PISSN: 10766294     EISSN: 19318448     Source Type: Journal    
DOI: 10.1089/mdr.2012.0025     Document Type: Article

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