The relationship between risk-taking propensity and the COMT Val158Met polymorphism among early adolescents as a function of sex

Journal of Psychiatric Research

Volumn 46, Issue 7, 2012, Pages 940-945

  Amstadter, Ananda B ^a   MacPherson, Laura ^b   Wang, Frances ^c   Banducci, Anne N ^b   Reynolds, Elizabeth K ^b,d   Potenza, Marc N ^e   Gelernter, Joel ^f   Lejuez, C W ^b  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

^c ARIZONA STATE UNIVERSITY   (United States)

^d BROWN UNIVERSITY   (United States)

^e YALE UNIVERSITY   (United States)

^f YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adolescents; BART; Dopamine; Risk taking

Indexed keywords

CATECHOL METHYLTRANSFERASE; DNA; METHIONINE; VALINE;

ADOLESCENT; ARTICLE; BALLOON ANALOG RISK TASK YOUTH VERSION; CHILD; CHILD BEHAVIOR; CONTROLLED STUDY; DNA EXTRACTION; EUROPEAN AMERICAN; FEMALE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HIGH RISK BEHAVIOR; HIGH RISK POPULATION; HOMOZYGOTE; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; PROPENSITY SCORE; RISK ASSESSMENT; SALIVA ANALYSIS; SCHOOL CHILD; SEX DIFFERENCE; SEXUAL BEHAVIOR; UNITED STATES;

EID: 84861998881     PISSN: 00223956     EISSN: 18791379     Source Type: Journal    
DOI: 10.1016/j.jpsychires.2012.04.010     Document Type: Article

References (45)

1. Anokhin A.P., Golosheykin S., Grant J., Heath A.C. Heritability of risk-taking in adolescence: a longitudinal twin study. Twin Research & Human Genetics 2009, 12:366-371.
2. Beck K.H., Thombs D.L., Mahoney C.A., Fingar K.M. Social context and sensation seeking: gender differences in college student drinking motivations. International Journal of the Addictions 1995, 30:1101-1115.
3. Blanco C., Hasin D.S., Petry N., Sinson F.S., Grant B.F. Sex differences in subclinical and DSM-IV pathological gambling: results from the national epidemiologic survey on alcohol and related conditions. Psychological Medicine 2006, 36:943-953.
4. Chen C., Chen C., Moyzis R., Dong Q., He Q., Zhu B., et al. Sex modulates the associations between the COMT gene and personality traits. Neuropsychopharmacology 2011, 36:1593-1598.
5. Dakof G.A. Understanding gender differences in adolescent drug abuse: issues of comorbity and family functioning. Journal of Psychoactive Drugs 2000, 32:25-32.
6. Desai R.A., Maciejewski P.K., Pantalon M.V., Potenza M.N. Gender differences in adolescent gambling. Annals of Clinical Psychiatry 2005, 17:249-258.
7. Desai R.A., Potenza M.N. Gender differences in the associations between past-year gambling problems and psychiatric disorders. Social Psychiatry and Psychiatric Epidemiology 2008, 4:173-183.
8. 158 M catechol-O-methyl-transferase polymorphism with panic disorder in women. International Journal of Neuropsychopharmacology 2004, 7:183-188.
9. 158 Met genotype and neural mechanisms related to affective arousal and regulation. Archives of General Psychiatry 2006, 63:1396-1406.
10. Dumontheil I., Roggeman C., Ziermans T., Peyrard-Janvid M., Matsson H., Kere J., Klingberg T. Influence of the COMT genotype on working memory and brain activity changes during development. Biological Psychiatry 2011, 70:222-229.
11. Eaton D.K., Kann L., Kinchen S., Shanklin S., Ross J., Hawkins J., et al. Youth risk behavior surveillance-United States, 2009. Morbidity and Mortality Weekly Report 2010, 59.
12. Egan M.F., Goldberg T.E., Kolachana B.S., Callicott J.H., Mazzanti C.M., Straub R.E., Goldman D., Weinberger D.R. Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia. Proceedings of the National Academy of Sciences of the United States of America 2001, 98(12):6917-6922.
13. Enoch M., Waheed J., Harris C., Albaugh B., Goldman D. Sex differences in the influence of COMT Val158Met on alcoholism and smoking in plains American Indians. Alcoholism: Clinical & Experimental Research 2006, 30:399-406.
14. Enoch M., Xu K., Ferro E., Harris C.R., Goldman D. Genetic origins of anxiety in women: a role for a functional catechol-O-methyltransferase polymorphism. Psychiatric Genetics 2003, 13:33-41.
15. Giakoumaki S.G., Roussos P., Bitsios P. Improvement of prepulse inhibition and executive function by the COMT inhibitor tolcapone depends on COMT Val158Met polymorphism. Neuropsychopharmacology 2008, 33:3058-3068.
16. Hariri A.R. The what, where, and when of catechol-O-methyltransferase. Biological Psychiatry 2011, 70:214-215.
17. Harrison P.J., Tunbridge E.M. Catechol-O-Methyltransferase (COMT): a gene contributing to sex differences in brain function, and to sexual dimorphism in the predisposition to psychiatric disorders. Neuropsychopharmacology 2008, 33:3037-3045.
18. Johnston L.D., O'Malley P.M., Bachman J.G., Schulenberg J.E. Monitoring the future national results on adolescent drug use: overview of key findings, 2010 2011, Institute for Social Research, The University of Michigan, Ann Arbor, MI, p. 77.
19. Karoum F., Chrapusta S.J., Egan M.F. 3-methoxytyramine is the major metabolite of released dopamine in the rat frontal cortex: reassessment of the effects of antipsychotics on the dynamics of dopamine release and metabolism in the frontal cortex, nucleus accumbens, and striatum by a simple two pool model. Journal of Neurochemistry 1994, 63:972-979.
20. Kreek M.J., Nielsen D.A., RButelman E.R., LaForge K.S. Genetic influences on impuslivity, risk taking, stress responsivity and vulnerability to drug abuse and addiction. Nature Neuroscience 2005, 8:1450-1458.
21. 158 Met genotype with sensation seeking personality trait. Neuropsychopharmacology 2007, 32:1950-1955.
22. Lejuez C.W., Aklin W., Daughters S., Zvolensky M.J., Kahler C.W., Gwadz M. Reliability and validity of the youth version of the Balloon Analogue Risk Task (BART-Y) in the assessment of risk-taking behavior among inner-city adolescents. Journal of Clinical Child and Adolescent Psychology 2007, 36:106-111.
23. Lejuez C.W., Read J.P., Kahler C.W., Richards J.B., Ramsey S.E., Stuart G.L., et al. Evaluation of a behavioral measure of risk taking: the Balloon Analogue Risk Task (BART). Journal of Experimental Psychology: Applied 2002, 8:75-84.
24. MacPherson L., Magidson J., Reynolds E.K., Kahler C.W., Lejuez C.W. Changes in sensation seeking and risk-taking propensity predict increases in alcohol use among early adolescents. Alcoholism: Clinical and Experimental Research 2010, 34:1400-1408.
25. MacPherson L., Reynolds E.K., Cassidy J., Daughters S., Mayes L., Wang F., et al. Positive and negative reinforcement underlying risk behavior in early adolescents. Prevention Science 2010, 11:331-342.
26. Männistö P., Kaakkola S. Catechol-O-methyltransferase (COMT): biochemistry, molecular biology, pharmacology, and clinical efficacy of the new selective COMT inhibitors. Pharmacological Reviews 1999, 51:593-628.
27. McGrath M., Kawachi I., Ascherio A., Colditz G.A., Hunter D.J., De Vivo I. Association between catechol-O-methyltransferase and phobic anxiety. The American Journal of Psychiatry 2004, 161:1703-1705.
28. McGue M., Iacono W.G. The association of early adolescent problem behavior with adult psychopathology. The American Journal of Psychiatry 2005, 162:1118-1124.
29. McGue M., Iacono W.G., Legrand L.N., Malone S., Elkins I. The origins of age at first drink. I. Associations with substance - use disorders, disinhibitory behavior and psychopathology, and P3 amplitude. Alcoholism: Clinical & Experimental Research 2001, 25:1156-1165.
30. Measelle J.R., Stice E., Springer D.W. A prospective test of the negative affect model of substance abuse: moderating effects of social support. Psychology of Addictive Behaviors 2006, 20:225-233.
31. Miles D.R., van den Bree M.M., Gupman A.E., Newlin D.B., Glantz M.D., Pickens R.W. A twin study on sensation seeking, risk taking behavior and marijuana use. Drug and Alcohol Dependence 2001, 62:57-68.
32. 158 Met polymorphism and propensity to anxiety in an Australian population-based longitudinal study of adolescent health. Psychiatric Genetics 2005, 15:109-115.
33. 158 Met and 5HTTLPR functional loci interact to predict persistence of anxiety across adolescence: results from the Victorian Adolescent Health Cohort Study. Genes, Brain, and Behavior 2007, 6:647-652.
34. 158 allele of catechol-O-methyltransferase (COMT) is associated with obsessive-compulsive disorder in men: case-control study and meta-analysis. Molecular Psychiatry 2007, 12:556-561.
35. Resnick H.S., Acierno R., Kilpatrick D.G. Health impact of interpersonal violence 2: medical and mental health outcomes. Behavioral Medicine 1997, 23:65-78.
36. Schinke S.P., Fan L., Cole K.C.A. Substance use among early adolescent girls: risk and protective factors. Journal of Adolescent Health 2008, 43.
37. Stein D., Newman T., Savitz J., Ramesar R. Warriors versus worriers: the role of COMT gene variants. CNS Spectrums: The International Journal of Neuropsychiatric Medicine 2006, 11:745-748.
38. Tiihonen J., Hallikainen T., Lachman H., Saito T., Volavka J., Salonen J.T., et al. Association between the functional variant of the catechol-O-methyltransferase (COMT) gene and type 1 alcoholism. Molecular Psychiatry 1999, 4:286-289.
39. Vandenbergh D.J., Rodriguez L.A., Miller I.T., Uhl G.R., Lachman H.M. High-activity catechol-O-methyltransferase allele is more prevalent in polysubstance abusers. American Journal of Medical Genetics 1997, 74:439-442.
40. Vijayraghavan S., Wang M., Birnbaum S.G., Williams G.V., Arnsten A.F. Inverted-U dopamine D1 receptor actions on prefrontal neurons engaged in working memory. Nature Neuroscience 2007, 10:376-384.
41. Wahl S.K., Turner L.R., Mermelstein R.J., Flay B.R. Adolescents' smoking expectancies: psychometric properties and prediction of behavior change. Nicotine and Tobacco Research 2005, 7:613-623.
42. Wang T.T., Franke P.P., Neidt H.H., Cichon S.S., Knapp M.M., Lichtermann D.D., et al. Association study of the low-activity allele of catechol-O-methyltransferase and alcoholism using a family-based approach. Molecular Psychiatry 2001, 6:109-111.
43. Waugh C.E., Dearing K.F., Joormann J., Gotlib I.H. Association between the catechol-O-methyltransferase Val158Met polymorphism and self-perceived social acceptance in adolescent girls. Journal of Child and Adolescent Psychopharmacology 2009, 19:395-401.
44. Wiers R.W., Hoogeveen K.J., Sergeant J.A., Gunning W.B. High and low dose expectancies and the differential associations with drinking in male and female adolescents and young adults. Addiction 1997, 92:871-888.
45. Woo J., Yoon K., Choi Y., Oh K., Lee Y., Yu B. The association between panic disorder and the L/L genotype of catechol-O methyltransferase. Journal of Psychiatric Research 2004, 38:365-370.