Association of the functional V158M catechol-O-methyl-transferase polymorphism with panic disorder in women

International Journal of Neuropsychopharmacology

Volumn 7, Issue 2, 2004, Pages 183-188

  Domschke, Katharina ^a   Freitag, Christine M ^c   Kuhlenbäumer, Gregor ^a   Schirmacher, Anja ^a   Sand, Philipp ^b   Nyhuis, Peter ^a   Jacob, Christian ^b   Fritze, Jürgen ^d   Franke, Petra ^c   Rietschel, Marcella ^c,f   Garritsen, Henk S ^a   Fimmers, Rolf ^c   Nöthen, Markus M ^e   Lesch, Klaus Peter ^b   Stögbauer, Florian ^a   Deckert, Jürgen ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c UNIVERSITY OF BONN   (Germany)

^d GOETHE UNIVERSITY   (Germany)

^e UNIVERSITY OF ANTWERP   (Belgium)

^f CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

Author keywords

Association; COMT; Gender; MAOA; Panic disorder

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; CATECHOL METHYLTRANSFERASE; METHIONINE; VALINE;

ADULT; ALLELE; AMINO ACID SUBSTITUTION; ANXIETY DISORDER; ARTICLE; CATECHOLAMINERGIC SYSTEM; CONTROLLED STUDY; FEMALE; GENDER; GENETIC ASSOCIATION; GENOTYPE; HERITABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PANIC; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGORAPHOBIA; ALLELES; CATECHOL O-METHYLTRANSFERASE; DNA PRIMERS; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; MALE; PANIC DISORDER; POLYMORPHISM, GENETIC; PSYCHIATRIC STATUS RATING SCALES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 3042678514     PISSN: 14611457     EISSN: None     Source Type: Journal    
DOI: 10.1017/S146114570400416X     Document Type: Article

References (29)

1. Deckert J, Catalano M, Syagailo YV, Bosi M, Okladnova O, Di Bella D, Nothen MM, Maffei P, Franke P, Fritze J, Maier W, Propping P, Beckmann H, Bellodi L, Lesch KP (1999). Excess of high activity monoamine oxidase A gene promoter alleles in female patients with panic disorder. Human Molecular Genetics 8, 621-624.
2. Eisenhofer G, Finberg JP (1994). Different metabolism of norepinephrine and epinephrine by catechol-O-methyltransferase and monoamine oxidase in rats. Journal of Pharmacology and Experimental Therapy 268, 1242-1251.
3. Fava M, Rosenbaum JF, Kolsky AR, Alpert JE, Nierenberg AA, Spillmann M, Moore C, Renshaw P, Bottiglieri T, Moroz G, Magni G (1999). Open study of the catechol-O-methyltransferase inhibitor tolcapone in major depressive disorder. Journal of Clinical Psychopharmacology 19, 329-335.
4. Gogos JA, Morgan M, Luine V, Santha M, Ogawa S, Pfaff D, Karayiorgou M (1998). Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior. Proceedings of the National Academy of Sciences USA 5, 9991-9996.
5. Gratacos M, Nadal M, Martin-Santos R, Pujana MA, Gago J, Peral B, Armengol L, Ponsa I, Miro R, Bulbena A, Estivill X (2001). A polymorphic genomic duplication on human chromosome 15 is a susceptibility factor for panic and phobic disorders. Cell 106, 367-379.
6. Hamilton SP, Fyer AJ, Durner M, Heiman GA, Baisre de Leon A, Hodge SE, Knowles JA, Weissman MM (2003). Further genetic evidence for a panic disorder syndrome mapping to chromosome 13q. Proceedings of the National Academy of Sciences USA 100, 2550-2555.
7. Hamilton SP, Slager SL, Heiman GA, Deng Z, Haghighi F, Klein DF, Hodge SE, Weissman MM, Fyer AJ, Knowles JA (2002). Evidence for a susceptibility locus for panic disorder near the catechol-O-methyltransferase gene on chromosome 22. Biological Psychiatry 51, 591-601.
8. Henderson AS, Korten AE, Jorm AF, Jacomb PA, Christensen H, Rodgers B, Tan X, Easteal S (2000). COMT and DRD3 polymorphisms, environmental exposures, and personality traits related to common mental disorders. American Journal of Medical Genetics 96, 102-107.
9. Hettema JM, Neale MC, Kendler KS (2001). A review and meta-analysis of the genetic epidemiology of anxiety disorders. American Journal of Psychiatry 158, 1568-1578.
10. Knowles JA, Fyer AJ, Vieland VJ, Weissman MM, Hodge SE, Heiman GA, Haghighi F, de Jesus GM, Rassnick H, Preud'homme-Rivelli X, Austin T, Cunjak J, Mick S, Fine LD, Woodley KA, Das K, Maier W, Adams PB, Freimer NB, Klein DF, Gilliam TC (1998). Results of a genome-wide genetic screen for panic disorder. American Journal of Medical Genetics 81, 139-147.
11. Lachman HM, Papolos DF, Saito T, Yu YM, Szumlanski CL, Weinshilboum RM (1996). Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics 6, 243-250.
12. Maier W, Lichtermann D, Minges J, Oehrlein A, Franke P (1993). A controlled family study in panic disorder. Journal of Psychiatric Research 27, 79-87.
13. Mannuzza S, Fyer AJ, Klein DF, Endicott J (1986). Schedule for Affective Disorders and Schizophrenia-Lifetime Version modified for the study of anxiety disorders (SADS-LA): rationale and conceptual development. Journal of Psychiatric Research 20, 317-325.
14. Mathew RJ, Ho BT, Kralik P, Taylor D, Claghorn JL (1980). MAO, DBH and COMT: the effect of anxiety. Journal of Clinical Psychiatry 41, 25-28.
15. Ohara K, Nagai M, Suzuki Y, Ochiai M (1998). No association between anxiety disorders and catechol-O-methyltransferase polymorphism. Psychiatry Research 80, 145-148.
16. Palmatier MA, Kang AM, Kidd KK (1999). Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles. Biological Psychiatry 46, 557-567.
17. Richard IH, Schiffer RB, Kurlan R (1996). Anxiety and Parkinson's disease. Journal of Neuropsychiatry and Clinical Neuroscience 8, 383-392.
18. Robins LN, Wing J, Wittchen HU, Helzer JE, Babor TF, Burke J, Farmer A, Jablenski A, Pickens R, Regier DA, Sartorius N, Towle LH (1988). The Composite International Diagnostic Interview. An epidemiologic instrument suitable for use in conjunction with different diagnostic systems and in different cultures. Archives of General Psychiatry 45, 1069-1077.
19. Rotondo A, Mazzanti C, Dell'Osso L, Rucci P, Sullivan P, Bouanani S, Gonnelli C, Goldman D, Cassano GB (2002). Catechol O-methyltransferase, serotonin transporter, and tryptophan hydroxylase gene polymorphisms in bipolar disorder patients with and without comorbid panic disorder. American Journal of Psychiatry 159, 23-29.
20. Sabol SZ, Hu S, Hamer D (1998). A functional polymorphism in the monoamine oxidase A gene promoter. Human Genetics 103, 273-279.
21. Sasieni PD (1997). From genotypes to genes: doubling the sample size. Biometrics 53, 1253-1261.
22. Shulman R, Griffiths J, Diewold P (1978). Catechol-O-methyl transferase activity in patients with depressive illness and anxiety states. British Journal of Psychiatry 132, 133-138.
23. Steinlein OK, Deckert J, Nothen MM, Franke P, Maier W, Beckmann H, Propping P (1997). Neuronal nicotinic acetylcholine receptor alpha 4 subunit (CHRNA4) and panic disorder: an association study. American Journal of Medical Genetics 74, 199-201.
24. Tyrer P, Shawcross C (1988). Monoamine oxidase inhibitors in anxiety disorders. Journal of Psychiatric Research 22, 87-98.
25. Vieland VJ, Goodman DW, Chapman T, Fyer AJ (1996). New segregation analysis of panic disorder. American Journal of Medical Genetics 67, 147-153.
26. Weissman MM, Bland RC, Canino GJ, Faravelli C, Greenwald S, Hwu HG, Joyce PR, Karam EG, Lee CK, Lellouch J, Lepine JP, Newman SC, Oakley-Browne MA, Rubio-Stipec M, Wells JE, Wickramaratne PJ, Wittchen HU, Yeh EK (1997). The cross-national epidemiology of panic disorder. Archives of General Psychiatry 54, 305-309.
27. Winqvist R, Lundstrom K, Salminen M, Laatikainen M, Ulmanen I (1991). Mapping of human catechol-O-methyltransferase gene to 22q11.2 and detection of a frequent RFLP with BglI. Cytogenetics and Cell Genetics 59, 253-257.
28. Wittchen HU, Garczynski E, Pfister H (1997). Composite International Diagnostic Interview according to ICD-10 and DSM-IV. Göttingen: Hogrefe.
29. Woo JM, Yoon KS, Yu BH (2002). Catechol O-methyl-transferase genetic polymorphism in panic disorder. American Journal of Psychiatry 159, 1785-1787.