Inhibition of T-type calcium current in rat thalamocortical neurons by isoflurane

Neuropharmacology

Volumn 63, Issue 2, 2012, Pages 266-273

  Eckle, Veit Simon ^a,b   DiGruccio, Michael R ^a   Uebele, Victor N ^c   Renger, John J ^c   Todorovic, Slobodan M ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Anesthetics; Burst firing; Isoflurane; Low voltage activated; Rodent thalamocortical neurons; T type calcium current

Indexed keywords

3,5 DICHLORO N [1 (2,2 DIMETHYL TETRAHYDRO PYRAN 4 YLMETHYL) 4 FLUORO PIPERIDIN 4 YLMETHYL]BENZAMIDE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL T TYPE; ISOFLURANE; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL;

ANESTHESIA MECHANISM; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; HYPERPOLARIZATION; IC 50; LATENT PERIOD; MALE; NERVE CELL EXCITABILITY; NERVE CELL INHIBITION; NERVE CELL MEMBRANE CONDUCTANCE; NERVE CELL MEMBRANE STEADY POTENTIAL; NEUROMODULATION; NONHUMAN; PATCH CLAMP; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; RAT; SENSORY STIMULATION; THALAMOCORTICAL TRACT; VOLTAGE CLAMP;

ACTION POTENTIALS; ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, T-TYPE; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; ISOFLURANE; MALE; MEMBRANE POTENTIALS; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; THALAMUS;

EID: 84861972868     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.03.018     Document Type: Article

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