Mechanisms of inhibition of CaV3.1 T-type calcium current by aliphatic alcohols

Neuropharmacology

Volumn 59, Issue 1-2, 2010, Pages 58-69

  Eckle, Veit Simon ^a,b   Todorovic, Slobodan M ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Alcohols; Anesthetics; Ca2+; Calcium; Low threshold activated; T type channels; Thalamus

Indexed keywords

ALKANOL; CALCIUM CHANNEL T TYPE; HEPTANOL; HEXANOL; OCTANOL; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED CALCIUM CHANNEL 3.1; CA(V)3.1 PROTEIN, RAT; CACNA1G PROTEIN, HUMAN; CALCIUM CHANNEL BLOCKING AGENT; FATTY ACID; ISOPROTEIN; RECOMBINANT PROTEIN;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; ELECTROPHYSIOLOGY; EXCITABILITY; FEMALE; HUMAN; HUMAN CELL; HYPERPOLARIZATION; IC 50; MALE; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; THALAMOCORTICAL TRACT; ANIMAL; BRAIN; BRAIN CORTEX; CELL LINE; CELL MEMBRANE POTENTIAL; DOSE RESPONSE; DRUG EFFECT; IN VITRO STUDY; METABOLISM; NERVE CELL; NERVE TRACT; PHYSIOLOGY; THALAMUS; WISTAR RAT;

ANIMALS; BRAIN; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, T-TYPE; CELL LINE; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; FATTY ACIDS; FEMALE; HUMANS; MALE; MEMBRANE POTENTIALS; NEURAL PATHWAYS; NEURONS; PROTEIN ISOFORMS; RATS; RATS, WISTAR; RECOMBINANT PROTEINS; THALAMUS;

EID: 77953285172     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2010.03.016     Document Type: Article

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