Using a physiologically based pharmacokinetic model to link urinary biomarker concentrations to dietary exposure of perchlorate

Chemosphere

Volumn 88, Issue 8, 2012, Pages 1019-1027

  Yang, Yuching ^a   Tan, Yu Mei ^b   Blount, Benjamin ^c   Murray, Clarence ^d   Egan, Sara ^d   Bolger, Michael ^d   Clewell, Harvey ^a  

^a HAMNER INSTITUTES FOR HEALTH SCIENCES   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^d CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Biomarker; Dietary exposure; Perchlorate; Physiologically based pharmacokinetic modeling

Indexed keywords

BIOMARKERS; FORECASTING; INORGANIC COMPOUNDS; PHARMACOKINETICS; PHYSIOLOGICAL MODELS; PHYSIOLOGY; POPULATION STATISTICS;

DIETARY EXPOSURE; EXPOSURE BIOMARKERS; PERCHLORATE; PERCHLORATE CONCENTRATION; PERCHLORATE EXPOSURE; PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELS; PREDICTING EXPOSURES; URINARY BIOMARKERS;

UNCERTAINTY ANALYSIS;

BIOLOGICAL MARKER; PERCHLORATE;

BIOMARKER; CONCENTRATION (COMPOSITION); DATA SET; DATABASE; DIET; DOSE-RESPONSE RELATIONSHIP; FOOD INTAKE; NUMERICAL MODEL; PERCHLORATE; PHYSIOLOGY; POLLUTION EXPOSURE; PUBLIC HEALTH; URINE;

ADULT; ARTICLE; DIETARY INTAKE; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PHYSIOLOGY; POPULATION RESEARCH; URINALYSIS;

UNITED STATES;

EID: 84861926811     PISSN: 00456535     EISSN: 18791298     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2012.03.074     Document Type: Article

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