Diversity and substrate specificity in the structures of steroidogenic cytochrome P450 enzymes

Biological and Pharmaceutical Bulletin

Volumn 35, Issue 6, 2012, Pages 818-823

  Sugimoto, Hiroshi ^a   Shiro, Yoshitsugu ^a  

^a RIKEN SPring 8 Center   (Japan)

Author keywords

Cytochrome P450; Steroid; Vitamin; X ray crystallography

Indexed keywords

ANASTROZOLE; AROMATASE; AROMATASE INHIBITOR; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); COLECALCIFEROL; CYTOCHROME P450; CYTOCHROME P450 24A1; FADROZOLE; LETROZOLE; STEROID HORMONE; UNCLASSIFIED DRUG; VOROZOLE;

BREAST CANCER; CATALYSIS; CONFORMATIONAL TRANSITION; DRUG METABOLISM; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; GENETIC VARIABILITY; HUMAN; MOLECULAR INTERACTION; NONHUMAN; PROTEIN FOLDING; REVIEW; STEROIDOGENESIS; THREE DIMENSIONAL IMAGING; X RAY CRYSTALLOGRAPHY; XENOBIOTIC METABOLISM;

EID: 84861912143     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.35.818     Document Type: Review

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