-
1
-
-
79952232216
-
Global cancer statistics
-
Jemal A, Bray F, CenterMM,Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin 2011;61:69-90.
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
2
-
-
0037444031
-
Pathological and molecular aspects of prostate cancer
-
DOI 10.1016/S0140-6736(03)12779-1
-
DeMarzo AM, Nelson WG, Isaacs WB, Epstein JI. Pathological and molecular aspects of prostate cancer. Lancet 2003;361:955-64. (Pubitemid 36332115)
-
(2003)
Lancet
, vol.361
, Issue.9361
, pp. 955-964
-
-
DeMarzo, A.M.1
Nelson, W.G.2
Isaacs, W.B.3
Epstein, J.I.4
-
3
-
-
77956793432
-
Molecular genetics of prostate cancer: New prospects for old challenges
-
Shen MM, Abate-Shen C. Molecular genetics of prostate cancer: new prospects for old challenges. Genes Dev 2010;24:1967-2000.
-
(2010)
Genes Dev
, vol.24
, pp. 1967-2000
-
-
Shen, M.M.1
Abate-Shen, C.2
-
4
-
-
52549087785
-
Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
-
Visvader JE, Lindeman GJ. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer 2008;8:755-68.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 755-768
-
-
Visvader, J.E.1
Lindeman, G.J.2
-
5
-
-
79953147370
-
A perspective on cancer cell metastasis
-
Chaffer CL, Weinberg RA. A perspective on cancer cell metastasis. Science 2011;331:1559-64.
-
(2011)
Science
, vol.331
, pp. 1559-1564
-
-
Chaffer, C.L.1
Weinberg, R.A.2
-
6
-
-
79952370202
-
The cancer stem cell: Premises, promises and challenges
-
Clevers H. The cancer stem cell: premises, promises and challenges. Nat Med 2011;17:313-9.
-
(2011)
Nat Med
, vol.17
, pp. 313-319
-
-
Clevers, H.1
-
7
-
-
78751676408
-
Cells of origin in cancer
-
Visvader JE. Cells of origin in cancer. Nature 2011;469:314-22.
-
(2011)
Nature
, vol.469
, pp. 314-322
-
-
Visvader, J.E.1
-
8
-
-
77249178726
-
Basal epithelial stem cells are efficient targets for prostate cancer initiation
-
Lawson DA, Zong Y, Memarzadeh S, Xin L, Huang J, Witte ON. Basal epithelial stem cells are efficient targets for prostate cancer initiation. Proc Natl Acad Sci U S A 2010;107:2610-5.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 2610-2615
-
-
Lawson, D.A.1
Zong, Y.2
Memarzadeh, S.3
Xin, L.4
Huang, J.5
Witte, O.N.6
-
9
-
-
77955121375
-
Identification of a cell of origin for human prostate cancer
-
Goldstein AS, Huang J, Guo C, Garraway IP, Witte ON. Identification of a cell of origin for human prostate cancer. Science 2010;329:568-71.
-
(2010)
Science
, vol.329
, pp. 568-571
-
-
Goldstein, A.S.1
Huang, J.2
Guo, C.3
Garraway, I.P.4
Witte, O.N.5
-
10
-
-
70349438989
-
A luminal epithelial stem cell that is a cell of origin for prostate cancer
-
Wang X, Kruithof-de Julio M, Economides KD, Walker D, Yu H, Halili MV, et al. A luminal epithelial stem cell that is a cell of origin for prostate cancer. Nature 2009;461:495-500.
-
(2009)
Nature
, vol.461
, pp. 495-500
-
-
Wang, X.1
Kruithof-de Julio, M.2
Economides, K.D.3
Walker, D.4
Yu, H.5
Halili, M.V.6
-
11
-
-
78751623400
-
Tumour-initiating stem-like cells in human prostate cancer exhibit increased NF-kappaB signalling
-
Rajasekhar VK, Studer L, Gerald W, Socci ND, Scher HI. Tumour-initiating stem-like cells in human prostate cancer exhibit increased NF-kappaB signalling. Nat Commun 2011;2:162.
-
(2011)
Nat Commun
, vol.2
, pp. 162
-
-
Rajasekhar, V.K.1
Studer, L.2
Gerald, W.3
Socci, N.D.4
Scher, H.I.5
-
12
-
-
77956615624
-
Primitive origins of prostate cancer: In vivo evidence for prostate-regenerating cells and prostate cancer-initiating cells
-
Goldstein AS, Stoyanova T, Witte ON. Primitive origins of prostate cancer: in vivo evidence for prostate-regenerating cells and prostate cancer-initiating cells. Mol Oncol 2010;4:385-96.
-
(2010)
Mol Oncol
, vol.4
, pp. 385-396
-
-
Goldstein, A.S.1
Stoyanova, T.2
Witte, O.N.3
-
13
-
-
45549091414
-
Prostate cancer stem cells: A new target for therapy
-
Maitland NJ, Collins AT. Prostate cancer stem cells: a new target for therapy. J Clin Oncol 2008;26:2862-70.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2862-2870
-
-
Maitland, N.J.1
Collins, A.T.2
-
14
-
-
0035515347
-
The ETS-domain transcription factor family
-
DOI 10.1038/35099076
-
Sharrocks AD. The ETS-domain transcription factor family. Nat Rev Mol Cell Biol 2001;2:827-37. (Pubitemid 33674083)
-
(2001)
Nature Reviews Molecular Cell Biology
, vol.2
, Issue.11
, pp. 827-837
-
-
Sharrocks, A.D.1
-
15
-
-
27544515095
-
ETS transcription factors and their emerging roles in human cancer
-
DOI 10.1016/j.ejca.2005.08.013, PII S0959804905007148, Transcription Factors in Cancer
-
Seth A, Watson DK. ETS transcription factors and their emerging roles in human cancer. Eur J Cancer 2005;41:2462-78. (Pubitemid 41540623)
-
(2005)
European Journal of Cancer
, vol.41
, Issue.16
, pp. 2462-2478
-
-
Seth, A.1
Watson, D.K.2
-
16
-
-
27344451557
-
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
-
DOI 10.1126/science.1117679
-
Tomlins SA, Rhodes DR, Perner S, Dhanasekaran SM, Mehra R, Sun XW, et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 2005;310:644-8. (Pubitemid 41528150)
-
(2005)
Science
, vol.310
, Issue.5748
, pp. 644-648
-
-
Tomlins, S.A.1
Rhodes, D.R.2
Perner, S.3
Dhanasekaran, S.M.4
Mehra, R.5
Sun, X.-W.6
Varambally, S.7
Cao, X.8
Tchinda, J.9
Kuefer, R.10
Lee, C.11
Montie, J.E.12
Shah, R.B.13
Pienta, K.J.14
Rubin, M.A.15
Chinnaiyan, A.M.16
-
17
-
-
34547642493
-
Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer
-
DOI 10.1038/nature06024, PII NATURE06024
-
Tomlins SA, Laxman B, Dhanasekaran SM, Helgeson BE, Cao X, Morris DS, et al. Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer. Nature 2007;448:595-9. (Pubitemid 47206938)
-
(2007)
Nature
, vol.448
, Issue.7153
, pp. 595-599
-
-
Tomlins, S.A.1
Laxman, B.2
Dhanasekaran, S.M.3
Helgeson, B.E.4
Cao, X.5
Morris, D.S.6
Menon, A.7
Jing, X.8
Cao, Q.9
Han, B.10
Yu, J.11
Wang, L.12
Montie, J.E.13
Rubin, M.A.14
Pienta, K.J.15
Roulston, D.16
Shah, R.B.17
Varambally, S.18
Mehra, R.19
Chinnaiyan, A.M.20
more..
-
18
-
-
33645750799
-
TMPRSS2:ETV4 gene fusions define a third molecular subtype of prostate cancer
-
Tomlins SA, Mehra R, Rhodes DR, Smith LR, Roulston D, Helgeson BE, et al. TMPRSS2:ETV4 gene fusions define a third molecular subtype of prostate cancer. Cancer Res 2006;66:3396-400.
-
(2006)
Cancer Res
, vol.66
, pp. 3396-3400
-
-
Tomlins, S.A.1
Mehra, R.2
Rhodes, D.R.3
Smith, L.R.4
Roulston, D.5
Helgeson, B.E.6
-
20
-
-
42949154207
-
Reduced expression and tumor suppressor function of the ETS transcription factor ESE-3 in prostate cancer
-
DOI 10.1038/sj.onc.1210953, PII 1210953
-
Cangemi R, Mensah A, Albertini V, Jain A, Mello-Grand M, Chiorino G, et al. Reduced expression and tumor suppressor function of the ETS transcription factor ESE-3 in prostate cancer. Oncogene 2008;27: 2877-85. (Pubitemid 351620453)
-
(2008)
Oncogene
, vol.27
, Issue.20
, pp. 2877-2885
-
-
Cangemi, R.1
Mensah, A.2
Albertini, V.3
Jain, A.4
Mello-Grand, M.5
Chiorino, G.6
Catapano, C.V.7
Carbone, G.M.8
-
21
-
-
77956285565
-
ETS transcription factors control transcription of EZH2 and epigenetic silencing of the tumor suppressor gene Nkx3.1 in prostate cancer
-
Kunderfranco P, Mello-Grand M, Cangemi R, Pellini S, Mensah A, Albertini V, et al. ETS transcription factors control transcription of EZH2 and epigenetic silencing of the tumor suppressor gene Nkx3.1 in prostate cancer. PLoS One 2010;5:e10547.
-
(2010)
PLoS One
, vol.5
-
-
Kunderfranco, P.1
Mello-Grand, M.2
Cangemi, R.3
Pellini, S.4
Mensah, A.5
Albertini, V.6
-
22
-
-
67649537602
-
Promoter-specific transcriptional interference and c-myc gene silencing by siRNAs in human cells
-
Napoli S, Pastori C, Magistri M, Carbone GM, Catapano CV. Promoter-specific transcriptional interference and c-myc gene silencing by siRNAs in human cells. EMBO J 2009;28:1708-19.
-
(2009)
EMBO J
, vol.28
, pp. 1708-1719
-
-
Napoli, S.1
Pastori, C.2
Magistri, M.3
Carbone, G.M.4
Catapano, C.V.5
-
23
-
-
4043134617
-
Triplex DNA-mediated downregulation of Ets2 expression results in growth inhibition and apoptosis in human prostate cancer cells
-
DOI 10.1093/nar/gkh744
-
Carbone GM, Napoli S, Valentini A, Cavalli F, Watson DK, Catapano CV. Triplex DNA-mediated downregulation of Ets2 expression results in growth inhibition and apoptosis in human prostate cancer cells. Nucleic Acids Res 2004;32:4358-67. (Pubitemid 39232308)
-
(2004)
Nucleic Acids Research
, vol.32
, Issue.14
, pp. 4358-4367
-
-
Carbone, G.M.1
Napoli, S.2
Valentini, A.3
Cavalli, F.4
Watson, D.K.5
Catapano, C.V.6
-
24
-
-
58549108859
-
The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations
-
Dubrovska A, Kim S, Salamone RJ, Walker JR, Maira SM, García-Echeverría C, et al. The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations. Proc Natl Acad Sci U S A 2009;106:268-73.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 268-273
-
-
Dubrovska, A.1
Kim, S.2
Salamone, R.J.3
Walker, J.R.4
Maira, S.M.5
García-Echeverría, C.6
-
25
-
-
10844295905
-
Androgen-induced differentiation and tumorigenicity of human prostate epithelial cells
-
DOI 10.1158/0008-5472.CAN-04-2938
-
Berger R, Febbo PG, Majumder PK, Zhao JJ, Mukherjee S, Signoretti S, et al. Androgen-induced differentiation and tumorigenicity of human prostate epithelial cells. Cancer Res 2004;64:8867-75. (Pubitemid 39665491)
-
(2004)
Cancer Research
, vol.64
, Issue.24
, pp. 8867-8875
-
-
Berger, R.1
Febbo, P.G.2
Majumder, P.K.3
Zhao, J.J.4
Mukherjee, S.5
Signoretti, S.6
Campbell, K.T.7
Sellers, W.R.8
Roberts, T.M.9
Loda, M.10
Golub, T.R.11
Hahn, W.C.12
-
26
-
-
0031431599
-
Androgen responsive adult human prostatic epithelial cell lines immortalized by human papillomavirus 18
-
DOI 10.1093/carcin/18.6.1215
-
Bello D, Webber MM, Kleinman HK, Wartinger DD, Rhim JS. Androgen responsive adult human prostatic epithelial cell lines immortalized by human papillomavirus 18. Carcinogenesis 1997;18:1215-23. (Pubitemid 28132513)
-
(1997)
Carcinogenesis
, vol.18
, Issue.6
, pp. 1215-1223
-
-
Bello, D.1
Webber, M.M.2
Kleinman, H.K.3
Wartinger, D.D.4
Rhim, J.S.5
-
27
-
-
43049165453
-
The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
-
DOI 10.1016/j.cell.2008.03.027, PII S0092867408004443
-
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008;133:704-15. (Pubitemid 351636299)
-
(2008)
Cell
, vol.133
, Issue.4
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.-J.3
Eaton, E.Ng.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
Campbell, L.L.11
Polyak, K.12
Brisken, C.13
Yang, J.14
Weinberg, R.A.15
-
28
-
-
63049123066
-
Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
-
Polyak K, Weinberg RA. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer 2009;9:265-73.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 265-273
-
-
Polyak, K.1
Weinberg, R.A.2
-
29
-
-
0037948854
-
In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
-
DOI 10.1101/gad.1061803
-
Dontu G, Abdallah WM, Foley JM, Jackson KW, Clarke MF, Kawamura MJ, et al. In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev 2003;17: 1253-70. (Pubitemid 36583168)
-
(2003)
Genes and Development
, vol.17
, Issue.10
, pp. 1253-1270
-
-
Dontu, G.1
Abdallah, W.M.2
Foley, J.M.3
Jackson, K.W.4
Clarke, M.F.5
Kawamura, M.J.6
Wicha, M.S.7
-
30
-
-
68749099671
-
Identification of selective inhibitors of cancer stem cells by high-throughput screening
-
Gupta PB, Onder TT, Jiang G, Tao K, Kuperwasser C, Weinberg RA, et al. Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell 2009;138:645-59.
-
(2009)
Cell
, vol.138
, pp. 645-659
-
-
Gupta, P.B.1
Onder, T.T.2
Jiang, G.3
Tao, K.4
Kuperwasser, C.5
Weinberg, R.A.6
-
31
-
-
79751473114
-
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
-
Liu C, Kelnar K, Liu B, Chen X, Calhoun-Davis T, Li H, et al. The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat Med 2011;17:211-5.
-
(2011)
Nat Med
, vol.17
, pp. 211-215
-
-
Liu, C.1
Kelnar, K.2
Liu, B.3
Chen, X.4
Calhoun-Davis, T.5
Li, H.6
-
32
-
-
43049103824
-
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
-
DOI 10.1038/ncb1722, PII NCB1722
-
Gregory PA, Bert AG, Paterson EL, Barry SC, Tsykin A, Farshid G, et al. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 2008;10:593-601. (Pubitemid 351627379)
-
(2008)
Nature Cell Biology
, vol.10
, Issue.5
, pp. 593-601
-
-
Gregory, P.A.1
Bert, A.G.2
Paterson, E.L.3
Barry, S.C.4
Tsykin, A.5
Farshid, G.6
Vadas, M.A.7
Khew-Goodall, Y.8
Goodall, G.J.9
-
33
-
-
78649669021
-
Bmi-1 is a crucial regulator of prostate stem cell self-renewal and malignant transformation
-
Lukacs RU, Memarzadeh S, Wu H, Witte ON. Bmi-1 is a crucial regulator of prostate stem cell self-renewal and malignant transformation. Cell Stem Cell 2010;7:682-93.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 682-693
-
-
Lukacs, R.U.1
Memarzadeh, S.2
Wu, H.3
Witte, O.N.4
-
34
-
-
36248966518
-
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
-
DOI 10.1016/j.cell.2007.11.019, PII S0092867407014717
-
Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007;131:861-72. (Pubitemid 350138099)
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
Yamanaka, S.7
-
35
-
-
62149122634
-
Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells
-
Ezhkova E, Pasolli HA, Parker JS, Stokes N, Su IH, Hannon G, et al. Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells. Cell 2009;136:1122-35.
-
(2009)
Cell
, vol.136
, pp. 1122-1135
-
-
Ezhkova, E.1
Pasolli, H.A.2
Parker, J.S.3
Stokes, N.4
Su, I.H.5
Hannon, G.6
-
36
-
-
50349093250
-
Characterization of TMPRSS2-ERG fusion high-grade prostatic intraepithelial neoplasia and potential clinical implications
-
Mosquera JM, Perner S, Genega EM, Sanda M, Hofer MD, Mertz KD, et al. Characterization of TMPRSS2-ERG fusion high-grade prostatic intraepithelial neoplasia and potential clinical implications. Clin Cancer Res 2008;14:3380-5.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3380-3385
-
-
Mosquera, J.M.1
Perner, S.2
Genega, E.M.3
Sanda, M.4
Hofer, M.D.5
Mertz, K.D.6
-
37
-
-
33749870551
-
TMPRSS2-ERG gene fusion causing ERG overexpression precedes chromosome copy number changes in prostate carcinomas and paired HGPIN lesions
-
DOI 10.1593/neo.06427
-
Cerveira N, Ribeiro FR, Peixoto A, Costa V, Henrique R, Jerónimo C, et al. TMPRSS2-ERG gene fusion causing ERG overexpression precedes chromosome copy number changes in prostate carcinomas and paired HGPIN lesions. Neoplasia 2006;8:826-32. (Pubitemid 44564838)
-
(2006)
Neoplasia
, vol.8
, Issue.10
, pp. 826-832
-
-
Cerveira, N.1
Ribeiro, F.R.2
Peixoto, A.3
Costa, V.4
Henrique, R.5
Jeronimo, C.6
Teixeira, M.R.7
-
38
-
-
2142717404
-
Gene expression profiling predicts clinical outcome of prostate cancer
-
DOI 10.1172/JCI200420032
-
Glinsky GV, Glinskii AB, Stephenson AJ, Hoffman RM, Gerald WL. Gene expression profiling predicts clinical outcome of prostate cancer. J Clin Invest 2004;113:913-23. (Pubitemid 38544150)
-
(2004)
Journal of Clinical Investigation
, vol.113
, Issue.6
, pp. 913-923
-
-
Glinsky, G.V.1
Glinskii, A.B.2
Stephenson, A.J.3
Hoffman, R.M.4
Gerald, W.L.5
-
39
-
-
38849190111
-
Tumor immunobiological differences in prostate cancer between African-American and European-American men
-
DOI 10.1158/0008-5472.CAN-07-2608
-
Wallace TA, Prueitt RL, Yi M, Howe TM, Gillespie JW, Yfantis HG, et al. Tumor immunobiological differences in prostate cancer between African-American and European-American men. Cancer Res 2008;68: 927-36. (Pubitemid 351206772)
-
(2008)
Cancer Research
, vol.68
, Issue.3
, pp. 927-936
-
-
Wallace, T.A.1
Prueitt, R.L.2
Yi, M.3
Howe, T.M.4
Gillespie, J.W.5
Yfantis, H.G.6
Stephens, R.M.7
Caporaso, N.E.8
Loffredo, C.A.9
Ambs, S.10
-
40
-
-
77957262381
-
Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
-
Taube JH, Herschkowitz JI, Komurov K, Zhou AY, Gupta S, Yang J, et al. Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes. Proc Natl Acad Sci U S A 2010;107:15449-54.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 15449-15454
-
-
Taube, J.H.1
Herschkowitz, J.I.2
Komurov, K.3
Zhou, A.Y.4
Gupta, S.5
Yang, J.6
-
41
-
-
67650999875
-
The basics of epithelial-mesenchymal transition
-
Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. J Clin Invest 2009;119:1420-8.
-
(2009)
J Clin Invest
, vol.119
, pp. 1420-1428
-
-
Kalluri, R.1
Weinberg, R.A.2
-
42
-
-
84862908058
-
Androgen deprivation causes epithelial-mesenchymal transition in the prostate: Implications for androgen-deprivation therapy
-
Sun Y, Wang BE, Leong KG, Yue P, Li L, Jhunjhunwala S, et al. Androgen deprivation causes epithelial-mesenchymal transition in the prostate: implications for androgen-deprivation therapy. Cancer Res 2012;72:527-36
-
(2012)
Cancer Res
, vol.72
, pp. 527-536
-
-
Sun, Y.1
Wang, B.E.2
Leong, K.G.3
Yue, P.4
Li, L.5
Jhunjhunwala, S.6
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