Inhibiting systemic autophagy during interleukin 2 immunotherapy promotes long-term tumor regression

Cancer Research

Volumn 72, Issue 11, 2012, Pages 2791-2801

  Liang, Xiaoyan ^a   De Vera, Michael E ^a   Buchser, William J ^a   Chavez, Antonio Romo De Vivar ^a   Loughran, Patricia ^a,b   Stolz, Donna Beer ^b   Basse, Per ^c   Wang, Tao ^b   Van Houten, Bennett ^b   Zeh III, Herbert J ^a   Lotze, Michael T ^a,c  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CASPASE 3; CHLOROQUINE; CYTOCHROME C; GAMMA INTERFERON; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 18; INTERLEUKIN 6; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; RECOMBINANT INTERLEUKIN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER IMMUNOTHERAPY; CANCER INHIBITION; CELL EXPANSION; CELL INFILTRATION; CELL METABOLISM; CELL NUCLEUS; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOSOL; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MEGADOSE; FEMALE; LIVER; LIVER CELL; LIVER METASTASIS; LONG TERM SURVIVAL; LOW DRUG DOSE; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; SPLEEN; SURVIVAL TIME; TUMOR REGRESSION;

ANIMALS; APOPTOSIS; AUTOPHAGY; CELL LINE, TUMOR; CELL PROLIFERATION; CHLOROQUINE; FEMALE; HMGB1 PROTEIN; IMMUNOTHERAPY; INTERLEUKIN-2; LIVER NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MITOCHONDRIA, LIVER;

EID: 84861893781     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-0320     Document Type: Article

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