Suppression of human detrusor smooth muscle excitability and contractility via pharmacological activation of large conductance Ca2+-activated K+ channels

American Journal of Physiology - Cell Physiology

Volumn 302, Issue 11, 2012, Pages 1632-1641

  Hristov, Kiril L ^a   Parajuli, Shankar P ^a   Soder, Rupal P ^a   Cheng, Qiuping ^a   Rovner, Eric S ^b   Petkov, Georgi V ^a,b  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

BK channels; Iberiotoxin; NS 1619; Patch clamp; Urinary bladder

Indexed keywords

1 (2 HYDROXY 5 TRIFLUOROMETHYLPHENYL) 5 TRIFLUOROMETHYL 2(3H) BENZIMIDAZOLONE; AMPHOTERICIN; CALCIUM ION; IBERIOTOXIN; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL;

ARTICLE; CONTROLLED STUDY; DETRUSOR MUSCLE; ELECTRIC FIELD; ELECTROSTIMULATION; EXCITABILITY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; HYPERPOLARIZATION; MEMBRANE STEADY POTENTIAL; MUSCLE FORCE; PATCH CLAMP; PRIORITY JOURNAL; SMOOTH MUSCLE CONTRACTILITY; SMOOTH MUSCLE TONE; WHOLE CELL;

AGED; AGED, 80 AND OVER; BENZIMIDAZOLES; CALCIUM; FEMALE; HUMANS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MALE; MEMBRANE POTENTIALS; MIDDLE AGED; MUSCLE CONTRACTION; MUSCLE, SMOOTH; MYOCYTES, SMOOTH MUSCLE; PATCH-CLAMP TECHNIQUES; PEPTIDES; URINARY BLADDER, OVERACTIVE;

EID: 84861866235     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00417.2011     Document Type: Article

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