-
1
-
-
34147119799
-
The Hormonal Control of Food Intake
-
DOI 10.1016/j.cell.2007.04.001, PII S0092867407004473
-
Coll AP, Farooqi IS, O'Rahilly S (2007) The hormonal control of food intake. Cell 129:251-262. (Pubitemid 46574977)
-
(2007)
Cell
, vol.129
, Issue.2
, pp. 251-262
-
-
Coll, A.P.1
Farooqi, I.S.2
O'Rahilly, S.3
-
2
-
-
0038714965
-
Neuropeptides: Opportunities for drug discovery
-
DOI 10.1016/S1474-4422(03)00482-4
-
Hökfelt T, Bartfai T, Bloom F (2003) Neuropeptides: Opportunities for drug discovery. Lancet Neurol 2:463-472. (Pubitemid 36876103)
-
(2003)
Lancet Neurology
, vol.2
, Issue.8
, pp. 463-472
-
-
Hokfelt, T.1
Bartfai, T.2
Bloom, F.3
-
3
-
-
0032568444
-
Altered nociception, analgesia and aggression in mice lacking the receptor for substance P
-
DOI 10.1038/32904
-
De Felipe C, et al. (1998) Altered nociception, analgesia and aggression in mice lacking the receptor for substance P. Nature 392:394-397. (Pubitemid 28168736)
-
(1998)
Nature
, vol.392
, Issue.6674
, pp. 394-397
-
-
De Felipe, C.1
Herrero, J.F.2
O'Brien, J.A.3
Palmer, J.A.4
Doyle, C.A.5
Smith, A.J.H.6
Laird, J.M.A.7
Belmonte, C.8
Cervero, F.9
Hunt, S.P.10
-
4
-
-
0019274399
-
A new class of angiotensin converting enzyme inhibitors
-
DOI 10.1038/288280a0
-
Patchett AA, et al. (1980) A new class of angiotensin-converting enzyme inhibitors. Nature 288:280-283. (Pubitemid 11165879)
-
(1980)
Nature
, vol.288
, Issue.5788
, pp. 280-283
-
-
Patchett, A.A.1
Harris, E.2
Tristram, E.W.3
-
5
-
-
0032577376
-
Signals that regulate food intake and energy homeostasis
-
DOI 10.1126/science.280.5368.1378
-
Woods SC, Seeley RJ, Porte D, Jr., Schwartz MW (1998) Signals that regulate food intake and energy homeostasis. Science 280:1378-1383. (Pubitemid 28264819)
-
(1998)
Science
, vol.280
, Issue.5368
, pp. 1378-1383
-
-
Woods, S.C.1
Seeley, R.J.2
Porte Jr., D.3
Schwartz, M.W.4
-
6
-
-
11144262776
-
Ghrelin: A gastric peptide that regulates food intake and energy homeostasis
-
DOI 10.1016/j.regpep.2004.08.007, PII S0167011504002897
-
Ueno H, Yamaguchi H, Kangawa K, Nakazato M (2005) Ghrelin: A gastric peptide that regulates food intake and energy homeostasis. Regul Pept 126:11-19. (Pubitemid 40037738)
-
(2005)
Regulatory Peptides
, vol.126
, Issue.1-2 SPEC. ISS.
, pp. 11-19
-
-
Ueno, H.1
Yamaguchi, H.2
Kangawa, K.3
Nakazato, M.4
-
7
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
DOI 10.1038/414799a
-
Saltiel AR, Kahn CR (2001) Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414:799-806. (Pubitemid 34000783)
-
(2001)
Nature
, vol.414
, Issue.6865
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
8
-
-
33947690115
-
Discovery of JANUVIA (sitagliptin), a selective dipeptidyl peptidase IV inhibitor for the treatment of type2 diabetes
-
DOI 10.2174/156802607780091028
-
Thornberry NA, Weber AE (2007) Discovery of JANUVIA (Sitagliptin), a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. Curr Top Med Chem 7:557-568. (Pubitemid 46488280)
-
(2007)
Current Topics in Medicinal Chemistry
, vol.7
, Issue.6
, pp. 557-568
-
-
Thornberry, N.A.1
Weber, A.E.2
-
9
-
-
0035859933
-
Identification of peptides from brain and pituitary of Cpe(fat)/Cpe(fat) mice
-
Che FY, et al. (2001) Identification of peptides from brain and pituitary of Cpe(fat)/Cpe(fat) mice. Proc Natl Acad Sci USA 98:9971-9976.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9971-9976
-
-
Che, F.Y.1
-
10
-
-
33750109567
-
Proprotein convertases: Lessons from knockouts
-
DOI 10.1096/fj.05-5491rev
-
Scamuffa N, Calvo F, Chrétien M, Seidah NG, Khatib AM (2006) Proprotein convertases: Lessons from knockouts. FASEB J 20:1954-1963. (Pubitemid 44953895)
-
(2006)
FASEB Journal
, vol.20
, Issue.12
, pp. 1954-1963
-
-
Scamuffa, N.1
Calvo, F.2
Chretien, M.3
Seidah, N.G.4
Khatib, A.-M.5
-
11
-
-
0033597852
-
Proteolytic processing in the secretory pathway
-
Zhou A, Webb G, Zhu X, Steiner DF (1999) Proteolytic processing in the secretory pathway. J Biol Chem 274:20745-20748.
-
(1999)
J Biol Chem
, vol.274
, pp. 20745-20748
-
-
Zhou, A.1
Webb, G.2
Zhu, X.3
Steiner, D.F.4
-
12
-
-
14844363404
-
Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients
-
DOI 10.1161/01.CIR.0000156466.02908.ED
-
Gradman AH, et al. (2005) Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients. Circulation 111:1012-1018. (Pubitemid 40354519)
-
(2005)
Circulation
, vol.111
, Issue.8
, pp. 1012-1018
-
-
Gradman, A.H.1
Schmieder, R.E.2
Lins, R.L.3
Nussberger, J.4
Chiang, Y.5
Bedigian, M.P.6
-
13
-
-
0034612348
-
Enhanced insulin secretion and improved glucose tolerance in mice lacking CD26
-
DOI 10.1073/pnas.120069197
-
Marguet D, et al. (2000) Enhanced insulin secretion and improved glucose tolerance in mice lacking CD26. Proc Natl Acad Sci USA 97:6874-6879. (Pubitemid 30412807)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.12
, pp. 6874-6879
-
-
Marguet, D.1
Baggio, L.2
Kobayashi, T.3
Bernard, A.-M.4
Pierres, M.5
Nielsen, P.F.6
Ribel, U.7
Watanabe, T.8
Drucker, D.J.9
Wagtmann, N.10
-
14
-
-
25844459084
-
Dipeptidyl peptidase IV inhibition for the treatment of type 2 diabetes: Potential importance of selectivity over dipeptidyl peptidases 8 and 9
-
DOI 10.2337/diabetes.54.10.2988
-
Lankas GR, et al. (2005) Dipeptidyl peptidase IV inhibition for the treatment of type 2 diabetes: Potential importance of selectivity over dipeptidyl peptidases 8 and 9. Diabetes 54:2988-2994. (Pubitemid 41401097)
-
(2005)
Diabetes
, vol.54
, Issue.10
, pp. 2988-2994
-
-
Lankas, G.R.1
Leiting, B.2
Roy, R.S.3
Eiermann, G.J.4
Beconi, M.G.5
Biftu, T.6
Chan, C.-C.7
Edmondson, S.8
Feeney, W.P.9
He, H.10
Ippolito, D.E.11
Kim, D.12
Lyons, K.A.13
Ok, H.O.14
Patel, R.A.15
Petrov, A.N.16
Pryor, K.A.17
Qian, X.18
Reigle, L.19
Woods, A.20
Wu, J.K.21
Zaller, D.22
Zhang, X.23
Zhu, L.24
Weber, A.E.25
Thornberry, N.A.26
more..
-
15
-
-
0019948176
-
Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products
-
DOI 10.1038/298240a0
-
Amara SG, Jonas V, Rosenfeld MG, Ong ES, Evans RM (1982) Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products. Nature 298:240-244. (Pubitemid 12089405)
-
(1982)
Nature
, vol.298
, Issue.5871
, pp. 240-244
-
-
Amara, S.G.1
Jonas, V.2
Rosenfeld, M.G.3
-
16
-
-
0021215649
-
Release of the predicted calcitonin gene-related peptide from cultured rat trigeminal ganglion cells
-
Mason RT, et al. (1984) Release of the predicted calcitonin gene-related peptide from cultured rat trigeminal ganglion cells. Nature 308:653-655. (Pubitemid 14129579)
-
(1984)
Nature
, vol.308
, Issue.5960
, pp. 653-655
-
-
Mason, R.T.1
Peterfreund, R.A.2
Sawchenko, P.E.3
-
17
-
-
0021997471
-
Calcitonin gene-related peptide is a potent vasodilator
-
DOI 10.1038/313054a0
-
Brain S, Williams T, Tippins J, Morris H (1985) Calcitonin gene-related peptide is a potent vasodilator. Nature 313:54-56. (Pubitemid 15192304)
-
(1985)
Nature
, vol.313
, Issue.5997
, pp. 54-56
-
-
Brain, S.D.1
Williams, T.J.2
Tippins, J.R.3
-
18
-
-
36749099014
-
Hypertension and dysregulated proinflammatory cytokine production in receptor activity-modifying protein 1-deficient mice
-
DOI 10.1073/pnas.0705974104
-
Tsujikawa K, et al. (2007) Hypertension and dysregulated proinflammatory cytokine production in receptor activity-modifying protein 1-deficient mice. Proc Natl Acad Sci USA 104:16702-16707. (Pubitemid 350211080)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.42
, pp. 16702-16707
-
-
Tsujikawa, K.1
Yayama, K.2
Hayashi, T.3
Matsushita, H.4
Yamaguchi, T.5
Shigeno, T.6
Ogitani, Y.7
Hirayama, M.8
Kato, T.9
Fukada, S.-I.10
Takatori, S.11
Kawasaki, H.12
Okamoto, H.13
Ikawa, M.14
Okabe, M.15
Yamamoto, H.16
-
19
-
-
0034192812
-
Evidence for increased plasma levels of calcitonin gene-related peptide in migraine outside of attacks
-
DOI 10.1016/S0304-3959(00)00232-3, PII S0304395900002323
-
Ashina M, Bendtsen L, Jensen R, Schifter S, Olesen J (2000) Evidence for increased plasma levels of calcitonin gene-related peptide in migraine outside of attacks. Pain 86:133-138. (Pubitemid 30211712)
-
(2000)
Pain
, vol.86
, Issue.1-2
, pp. 133-138
-
-
Ashina, M.1
Bendtsen, L.2
Jensen, R.3
Schifter, S.4
Olesen, J.5
-
20
-
-
51549089370
-
Clinical and preclinical rationale for CGRP-receptor antagonists in the treatment of migraine
-
Tepper SJ, Stillman MJ (2008) Clinical and preclinical rationale for CGRP-receptor antagonists in the treatment of migraine. Headache 48:1259-1268.
-
(2008)
Headache
, vol.48
, pp. 1259-1268
-
-
Tepper, S.J.1
Stillman, M.J.2
-
21
-
-
1542346238
-
Calcitonin Gene-Related Peptide Receptor Antagonist BIBN 4096 BS for the Acute Treatment of Migraine
-
DOI 10.1056/NEJMoa030505
-
Olesen J, et al.; BIBN 4096 BS Clinical Proof of Concept Study Group (2004) Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine. N Engl J Med 350:1104-1110. (Pubitemid 38298990)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.11
, pp. 1104-1110
-
-
Olesen, J.1
Diener, H.-C.2
Husstedt, I.W.3
Goadsby, P.J.4
Hall, D.5
Meier, U.6
Pollentier, S.7
Lesko, L.M.8
-
22
-
-
78049443064
-
Activation of TRPV1 by dietary capsaicin improves endothelium-dependent vasorelaxation and prevents hypertension
-
Yang D, et al. (2010) Activation of TRPV1 by dietary capsaicin improves endothelium-dependent vasorelaxation and prevents hypertension. Cell Metab 12:130-141.
-
(2010)
Cell Metab
, vol.12
, pp. 130-141
-
-
Yang, D.1
-
23
-
-
0025822334
-
Catabolism of calcitonin gene-related peptide and substance P by neutral endopeptidase
-
Katayama M, et al. (1991) Catabolism of calcitonin gene-related peptide and substance P by neutral endopeptidase. Peptides 12:563-567.
-
(1991)
Peptides
, vol.12
, pp. 563-567
-
-
Katayama, M.1
-
24
-
-
0031048807
-
Isolation and identification of CGRP C-terminal fragments in the rat spinal cord
-
DOI 10.1016/S0143-4179(97)90014-7
-
Le Grevès P, Andersson K, Silberring J (1997) Isolation and identification of CGRP Cterminal fragments in the rat spinal cord. Neuropeptides 31:19-23. (Pubitemid 27112609)
-
(1997)
Neuropeptides
, vol.31
, Issue.1
, pp. 19-23
-
-
Le, G.P.1
Andersson, K.2
Silberring, J.3
-
25
-
-
0024324450
-
Calcitonin gene-related peptide is metabolized by an endopeptidase hydrolyzing substance P
-
DOI 10.1016/0167-0115(89)90176-6
-
Le Grevès P, Nyberg F, Hökfelt T, Terenius L (1989) Calcitonin gene-related peptide is metabolized by an endopeptidase hydrolyzing substance P. Regul Pept 25:277-286. (Pubitemid 19182278)
-
(1989)
Regulatory Peptides
, vol.25
, Issue.3
, pp. 277-286
-
-
Le, G.P.1
Nyberg, F.2
Hokfelt, T.3
Terenius, L.4
-
26
-
-
0025455517
-
Degradation of airway neuropeptides by human lung tryptase
-
Tam EK, Caughey GH (1990) Degradation of airway neuropeptides by human lung tryptase. Am J Respir Cell Mol Biol 3:27-32.
-
(1990)
Am J Respir Cell Mol Biol
, vol.3
, pp. 27-32
-
-
Tam, E.K.1
Caughey, G.H.2
-
27
-
-
42949085229
-
Peptidomics in drug research
-
DOI 10.1517/17460441.3.4.425
-
Clynen E, Baggerman G, Husson S, Landuyt B, Schoofs L (2008) Peptidomics in drug research. Expert Opinion on Drug Discovery 3:425-440. (Pubitemid 351618769)
-
(2008)
Expert Opinion on Drug Discovery
, vol.3
, Issue.4
, pp. 425-440
-
-
Clynen, E.1
Baggerman, G.2
Husson, S.J.3
Landuyt, B.4
Schoofs, L.5
-
28
-
-
33846417985
-
Mass-spectrometric identification of a novel angiotensin peptide in human plasma
-
DOI 10.1161/01.ATV.0000253889.09765.5f, PII 0004360520070200000008
-
Jankowski V, et al. (2007) Mass-spectrometric identification of a novel angiotensin peptide in human plasma. Arterioscler Thromb Vasc Biol 27:297-302. (Pubitemid 46143043)
-
(2007)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.27
, Issue.2
, pp. 297-302
-
-
Jankowski, V.1
Vanholder, R.2
Van Der, G.M.3
Tolle, M.4
Karadogan, S.5
Gobom, J.6
Furkert, J.7
Oksche, A.8
Krause, E.9
Tran, T.N.A.10
Tepel, M.11
Schuchardt, M.12
Schluter, H.13
Wiedon, A.14
Beyermann, M.15
Bader, M.16
Todiras, M.17
Zidek, W.18
Jankowski, J.19
-
29
-
-
77949821699
-
Expanding the dipeptidyl peptidase 4-regulated peptidome via an optimized peptidomics platform
-
Tinoco AD, Tagore DM, Saghatelian A (2010) Expanding the dipeptidyl peptidase 4-regulated peptidome via an optimized peptidomics platform. J Am Chem Soc 132:3819-3830.
-
(2010)
J Am Chem Soc
, vol.132
, pp. 3819-3830
-
-
Tinoco, A.D.1
Tagore, D.M.2
Saghatelian, A.3
-
32
-
-
0036708007
-
Mapping sequence differences between thimet oligopeptidase and neurolysin implicates key residues in substrate recognition
-
DOI 10.1110/ps.0216302
-
Ray K, Hines CS, Rodgers DW (2002) Mapping sequence differences between thimet oligopeptidase and neurolysin implicates key residues in substrate recognition. Protein Sci 11:2237-2246. (Pubitemid 34919627)
-
(2002)
Protein Science
, vol.11
, Issue.9
, pp. 2237-2246
-
-
Ray, K.1
Hines, C.S.2
Rodgers, D.W.3
-
33
-
-
0035836450
-
Substrate specificity characterization of recombinant metallo oligo-peptidases thimet oligopeptidase and neurolysin
-
DOI 10.1021/bi002715k
-
Oliveira V, et al. (2001) Substrate specificity characterization of recombinant metallo oligo-peptidases thimet oligopeptidase and neurolysin. Biochemistry 40:4417-4425. (Pubitemid 32319587)
-
(2001)
Biochemistry
, vol.40
, Issue.14
, pp. 4417-4425
-
-
Oliveira, V.1
Campos, M.2
Melo, R.L.3
Ferro, E.S.4
Camargo, A.C.M.5
Juliano, M.A.6
Juliano, L.7
-
34
-
-
0037390039
-
Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo
-
DOI 10.1073/pnas.0230450100
-
Farris W, et al. (2003) Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo. Proc Natl Acad Sci USA 100:4162-4167. (Pubitemid 36418174)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.7
, pp. 4162-4167
-
-
Farris, W.1
Mansourian, S.2
Chang, Y.3
Lindsley, L.4
Eckman, E.A.5
Frosch, M.P.6
Eckman, C.B.7
Tanzi, R.E.8
Selkoe, D.J.9
Guenette, S.10
-
35
-
-
33750302461
-
Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism
-
DOI 10.1038/nature05143, PII NATURE05143
-
Shen Y, Joachimiak A, Rosner MR, Tang WJ (2006) Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism. Nature 443:870-874. (Pubitemid 44622699)
-
(2006)
Nature
, vol.443
, Issue.7113
, pp. 870-874
-
-
Shen, Y.1
Joachimiak, A.2
Rich, R.M.3
Tang, W.-J.4
-
36
-
-
0037947406
-
Amyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivo
-
DOI 10.1073/pnas.1031520100
-
Miller BC, et al. (2003) Amyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivo. Proc Natl Acad Sci USA 100:6221-6226. (Pubitemid 36576957)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.10
, pp. 6221-6226
-
-
Miller, B.C.1
Eckman, E.A.2
Sambamurti, K.3
Dobbs, N.4
Martin, C.K.5
Eckman, C.B.6
Hersh, L.B.7
Thiele, D.L.8
-
37
-
-
34548857069
-
Peptidomic identification and biological validation of neuroendocrine regulatory peptide-1 and -2
-
DOI 10.1074/jbc.M701665200
-
Yamaguchi H, et al. (2007) Peptidomic identification and biological validation of neuroendocrine regulatory peptide-1 and -2. J Biol Chem 282:26354-26360. (Pubitemid 47443772)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.36
, pp. 26354-26360
-
-
Yamaguchi, H.1
Sasaki, K.2
Satomi, Y.3
Shimbara, T.4
Kageyama, H.5
Mondal, M.S.6
Toshinai, K.7
Date, Y.8
Gonzalez, L.J.9
Shioda, S.10
Takao, T.11
Nakazato, M.12
Minamino, N.13
-
38
-
-
84860215655
-
Statins in Unconventional Secretion of Insulin-Degrading Enzyme and Degradation of the Amyloid-β Peptide
-
Glebov K, Walter J (2012) Statins in Unconventional Secretion of Insulin-Degrading Enzyme and Degradation of the Amyloid-β Peptide. Neurodegener Dis 10:309-312.
-
(2012)
Neurodegener Dis
, vol.10
, pp. 309-312
-
-
Glebov, K.1
Walter, J.2
-
39
-
-
78549284024
-
Statins promote the degradation of extracellular amyloid beta-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion
-
Tamboli IY, et al. (2010) Statins promote the degradation of extracellular amyloid beta-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion. J Biol Chem 285:37405-37414.
-
(2010)
J Biol Chem
, vol.285
, pp. 37405-37414
-
-
Tamboli, I.Y.1
-
40
-
-
71049187147
-
Quantification of cardiovascular biomarkers in patient plasma by targeted mass spectrometry and stable isotope dilution
-
Keshishian H, et al. (2009) Quantification of cardiovascular biomarkers in patient plasma by targeted mass spectrometry and stable isotope dilution. Mol Cell Proteomics 8:2339-2349.
-
(2009)
Mol Cell Proteomics
, vol.8
, pp. 2339-2349
-
-
Keshishian, H.1
-
41
-
-
33847176604
-
A genome-wide association study identifies novel risk loci for type 2 diabetes
-
Sladek R, et al. (2007) A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 445:881-885.
-
(2007)
Nature
, vol.445
, pp. 881-885
-
-
Sladek, R.1
-
42
-
-
34249895023
-
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
-
DOI 10.1126/science.1142364
-
Zeggini E, et al.; Wellcome Trust Case Control Consortium (WTCCC) (2007) Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 316:1336-1341. (Pubitemid 46871654)
-
(2007)
Science
, vol.316
, Issue.5829
, pp. 1336-1341
-
-
Zeggini, E.1
Weedon, M.N.2
Lindgren, C.M.3
Frayling, T.M.4
Elliott, K.S.5
Lango, H.6
Timpson, N.J.7
Perry, J.R.B.8
Rayner, N.W.9
Freathy, R.M.10
Barrett, J.C.11
Shields, B.12
Morris, A.P.13
Ellard, S.14
Groves, C.J.15
Harries, L.W.16
Marchini, J.L.17
Owen, K.R.18
Knight, B.19
Cardon, L.R.20
Walker, M.21
Hitman, G.A.22
Morris, A.D.23
Doney, A.S.F.24
McCarthy, M.I.25
Hattersley, A.T.26
Bruce, I.N.27
Donovan, H.28
Eyre, S.29
Gilbert, P.D.30
Hider, S.L.31
Hinks, A.M.32
John, S.L.33
Potter, C.34
Silman, A.J.35
Symmons, D.P.M.36
Thomson, W.37
Worthington, J.38
more..
-
43
-
-
0034704198
-
Evidence for genetic linkage Alzheimer's disease to chromosome 10q
-
DOI 10.1126/science.290.5500.2302
-
Bertram L, et al. (2000) Evidence for genetic linkage of Alzheimer's disease to chromosome 10q. Science 290:2302-2303. (Pubitemid 32041570)
-
(2000)
Science
, vol.290
, Issue.5500
, pp. 2302-2303
-
-
Bertram, L.1
Blacker, D.2
Mullin, K.3
Keeney, D.4
Jones, J.5
Basu, S.6
Yhu, S.7
McInnis, M.G.8
Go, R.C.P.9
Vekrellis, K.10
Selkoe, D.J.11
Saunders, A.J.12
Tanzi, R.E.13
-
44
-
-
1642290835
-
Partial Loss-of-Function Mutations in Insulin-Degrading Enzyme that Induce Diabetes also Impair Degradation of Amyloid beta-Protein
-
Farris W, et al. (2004) Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein. Am J Pathol 164:1425-1434. (Pubitemid 38387808)
-
(2004)
American Journal of Pathology
, vol.164
, Issue.4
, pp. 1425-1434
-
-
Farris, W.1
Mansourian, S.2
Leissring, M.A.3
Eckman, E.A.4
Bertram, L.5
Eckman, C.B.6
Tanzi, R.E.7
Selkoe, D.J.8
-
45
-
-
13844266724
-
Sequence variants of IDE are associated with the extent of beta-amyloid deposition in the Alzheimer's disease brain
-
DOI 10.1016/j.neurobiolaging.2004.07.011
-
Blomqvist ME, et al. (2005) Sequence variants of IDE are associated with the extent of beta-amyloid deposition in the Alzheimer's disease brain. Neurobiol Aging 26:795-802. (Pubitemid 40249481)
-
(2005)
Neurobiology of Aging
, vol.26
, Issue.6
, pp. 795-802
-
-
Blomqvist, M.E.-L.1
Chalmers, K.2
Andreasen, N.3
Bogdanovic, N.4
Wilcock, G.K.5
Cairns, N.J.6
Feuk, L.7
Brookes, A.J.8
Love, S.9
Blennow, K.10
Kehoe, P.G.11
Prince, J.A.12
-
46
-
-
67649197985
-
Small-molecule activators of insulin-degrading enzyme discovered through high-throughput compound screening
-
Cabrol C, et al. (2009) Small-molecule activators of insulin-degrading enzyme discovered through high-throughput compound screening. PLoS ONE 4:e5274.
-
(2009)
PLoS ONE
, vol.4
-
-
Cabrol, C.1
-
47
-
-
77956274306
-
Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin
-
Leissring MA, et al. (2010) Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin. PLoS ONE 5:e10504.
-
(2010)
PLoS ONE
, vol.5
-
-
Leissring, M.A.1
-
48
-
-
70350266819
-
The RAPID method for blood processing yields new insight in plasma concentrations and molecular forms of circulating gut peptides
-
Stengel A, et al. (2009) The RAPID method for blood processing yields new insight in plasma concentrations and molecular forms of circulating gut peptides. Endocrinology 150:5113-5118.
-
(2009)
Endocrinology
, vol.150
, pp. 5113-5118
-
-
Stengel, A.1
|