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Volumn 52, Issue 6, 2012, Pages 940-946

Effect of quercetin on CYP3A activity in chinese healthy participants

Author keywords

CYP3A; midazolam; quercetin

Indexed keywords

ALPHA HYDROXYMIDAZOLAM; CYTOCHROME P450 3A; MIDAZOLAM; QUERCETIN;

EID: 84861798548     PISSN: 00912700     EISSN: 15524604     Source Type: Journal    
DOI: 10.1177/0091270011406278     Document Type: Article
Times cited : (20)

References (24)
  • 1
    • 0029999052 scopus 로고    scopus 로고
    • Phase i clinical trial of the flavonoid quercetin: Pharmacokinetics and evidence for in vivo tyrosine kinase inhibition
    • Ferry DR, Smith A, Malkhandi J, et al. Phase I clinical trial of the flavonoid quercetin: pharmacokinetics and evidence for in vivo tyrosine kinase inhibition. Clin Cancer Res. 1996 ; 2: 659-668
    • (1996) Clin Cancer Res , vol.2 , pp. 659-668
    • Ferry, D.R.1    Smith, A.2    Malkhandi, J.3
  • 2
    • 0034108013 scopus 로고    scopus 로고
    • Bioavailability and metabolism of the flavonol quercetin in the pig
    • Ader P, Wessmann A, Wolffram S. Bioavailability and metabolism of the flavonol quercetin in the pig. Free Radic Biol Med. 2000 ; 28: 1056-1067
    • (2000) Free Radic Biol Med , vol.28 , pp. 1056-1067
    • Ader, P.1    Wessmann, A.2    Wolffram, S.3
  • 3
    • 0001954020 scopus 로고
    • Quercetin: Nature's antihistamine
    • Murray MT. Quercetin: nature's antihistamine. Better Nutr. 1990 ; 60: 10
    • (1990) Better Nutr , vol.60 , pp. 10
    • Murray, M.T.1
  • 4
    • 0034202211 scopus 로고    scopus 로고
    • Antioxidants and cancer III: Quercetin
    • Lamson DW, Brignall MS. Antioxidants and cancer III: quercetin. Alternat Med Rev. 2000 ; 5: 196-208
    • (2000) Alternat Med Rev , vol.5 , pp. 196-208
    • Lamson, D.W.1    Brignall, M.S.2
  • 6
    • 0036892578 scopus 로고    scopus 로고
    • Pharmacokinetics of midazolam and 1a-hydroxy-midazolam in Chinese with different CYP3A5 genotypes
    • Shih PS, Huang JD. Pharmacokinetics of midazolam and 1a-hydroxy-midazolam in Chinese with different CYP3A5 genotypes. Drug Metab Dispos. 2002 ; 30: 1491-1496
    • (2002) Drug Metab Dispos , vol.30 , pp. 1491-1496
    • Shih, P.S.1    Huang, J.D.2
  • 7
    • 1642338852 scopus 로고    scopus 로고
    • Mechanisms of action and therapeutic efficacy of ursodeoxycholic acid in cholestatic liver disease
    • Paumgartner G, Beuers U. Mechanisms of action and therapeutic efficacy of ursodeoxycholic acid in cholestatic liver disease. Clin Liver Dis. 2004 ; 8: 67-81
    • (2004) Clin Liver Dis , vol.8 , pp. 67-81
    • Paumgartner, G.1    Beuers, U.2
  • 8
    • 0030015297 scopus 로고    scopus 로고
    • Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism
    • Thummel KE, O'Shea D, Paine MF, et al. Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism. Clin Pharmacol Ther. 1996 ; 59: 491-502
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 491-502
    • Thummel, K.E.1    O'Shea, D.2    Paine, M.F.3
  • 9
    • 0032907322 scopus 로고    scopus 로고
    • Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein
    • Kim RB, Wandel C, Leake B, et al. Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein. Pharm Res. 1999 ; 16: 408-414
    • (1999) Pharm Res , vol.16 , pp. 408-414
    • Kim, R.B.1    Wandel, C.2    Leake, B.3
  • 10
    • 0036881095 scopus 로고    scopus 로고
    • Sex-related differences in the clearance of cytochrome P450 3A4 substrates may be caused by P-glycoprotein
    • Cummins CL, Wu CY, Benet LZ. Sex-related differences in the clearance of cytochrome P450 3A4 substrates may be caused by P-glycoprotein. Clin Pharmacol Ther. 2002 ; 72: 474-489
    • (2002) Clin Pharmacol Ther , vol.72 , pp. 474-489
    • Cummins, C.L.1    Wu, C.Y.2    Benet, L.Z.3
  • 11
    • 34548406596 scopus 로고    scopus 로고
    • Effect of quercetin on the activities of cytochrome p450 1A1 in L-02 cell lines and human liver microsomes [in Chinese]
    • Zhu YP, Jin NZ, Zhou JW, Mao L, Zhao RC, Tong J. Effect of quercetin on the activities of cytochrome p450 1A1 in L-02 cell lines and human liver microsomes [in Chinese]. Zhonghua Gan Zang Bing Za Zhi. 2005 ; 13: 233-234
    • (2005) Zhonghua Gan Zang Bing Za Zhi , vol.13 , pp. 233-234
    • Zhu, Y.P.1    Jin, N.Z.2    Zhou, J.W.3    Mao, L.4    Zhao, R.C.5    Tong, J.6
  • 12
    • 3843050465 scopus 로고    scopus 로고
    • Expression of HSP70 and P-glycoprotein (P-gp) in human hepatocarcinoma HepG2 cells induced by heat shock and inhibiting effect of quercetin on them
    • Tang WB, Ma PQ, Ni H, Zeng WT, Zhu KL. Expression of HSP70 and P-glycoprotein (P-gp) in human hepatocarcinoma HepG2 cells induced by heat shock and inhibiting effect of quercetin on them. Ai Zheng. 2003 ; 22: 954-958
    • (2003) Ai Zheng , vol.22 , pp. 954-958
    • Tang, W.B.1    Ma, P.Q.2    Ni, H.3    Zeng, W.T.4    Zhu, K.L.5
  • 13
    • 0037032676 scopus 로고    scopus 로고
    • Quercetin significantly decreased cyclosporin oral bioavailability in pigs and rats
    • Hsiu SL, Hou YC, Wang YH, Tsao CW, Su SF, Chao PD. Quercetin significantly decreased cyclosporin oral bioavailability in pigs and rats. Life Sci. 2002 ; 72: 227-235
    • (2002) Life Sci , vol.72 , pp. 227-235
    • Hsiu, S.L.1    Hou, Y.C.2    Wang, Y.H.3    Tsao, C.W.4    Su, S.F.5    Chao, P.D.6
  • 14
    • 3843064658 scopus 로고    scopus 로고
    • The inhibitory effects of herbal components on CYP2C9 and CYP3A4 catalytic activities in human liver microsomes
    • He N, Edeki T. The inhibitory effects of herbal components on CYP2C9 and CYP3A4 catalytic activities in human liver microsomes. Am J Ther. 2004 ; 11: 206-212
    • (2004) Am J Ther , vol.11 , pp. 206-212
    • He, N.1    Edeki, T.2
  • 15
    • 0035734306 scopus 로고    scopus 로고
    • Inhibition of human CYP3A4 activity by grapefruit flavonoids, furanocoumarins and related compounds
    • Ho PC, Saville DJ, Wanwimolruk S. Inhibition of human CYP3A4 activity by grapefruit flavonoids, furanocoumarins and related compounds. J Pharm Pharm Sci. 2001 ; 4: 217-227
    • (2001) J Pharm Pharm Sci , vol.4 , pp. 217-227
    • Ho, P.C.1    Saville, D.J.2    Wanwimolruk, S.3
  • 16
    • 0028593949 scopus 로고
    • Extraction of high quality genomic DNA from microsamples of human blood
    • Ma HW, Cheng J, Caddy B. Extraction of high quality genomic DNA from microsamples of human blood. J Forensic Sci Soc. 1994 ; 34: 231-235
    • (1994) J Forensic Sci Soc , vol.34 , pp. 231-235
    • Ma, H.W.1    Cheng, J.2    Caddy, B.3
  • 17
    • 0036517359 scopus 로고    scopus 로고
    • Polymorphism analysis of CYP3A5 in myeloid leukemia
    • Liu TC, Lin SF, Chen TP, Chang JG. Polymorphism analysis of CYP3A5 in myeloid leukemia. Oncol Rep. 2002 ; 9: 327-329
    • (2002) Oncol Rep , vol.9 , pp. 327-329
    • Liu, T.C.1    Lin, S.F.2    Chen, T.P.3    Chang, J.G.4
  • 18
    • 1642579696 scopus 로고    scopus 로고
    • The pregnane X receptor binds to response elements in a genomic context-dependent manner, and PXR activator rifampicin selectively alters the binding among target genes
    • Song X, Xie M, Zhang H, Li Y, Sachdeva K, Yan B. The pregnane X receptor binds to response elements in a genomic context-dependent manner, and PXR activator rifampicin selectively alters the binding among target genes. Drug Metab Dispos. 2004 ; 32: 35-42
    • (2004) Drug Metab Dispos , vol.32 , pp. 35-42
    • Song, X.1    Xie, M.2    Zhang, H.3    Li, Y.4    Sachdeva, K.5    Yan, B.6
  • 19
    • 0034676513 scopus 로고    scopus 로고
    • Use of the nuclear receptor PXR to predict drug interactions
    • Moore JT, Kliewer SA. Use of the nuclear receptor PXR to predict drug interactions. Toxicology. 2000 ; 153: 1-10
    • (2000) Toxicology , vol.153 , pp. 1-10
    • Moore, J.T.1    Kliewer, S.A.2
  • 20
    • 0037067665 scopus 로고    scopus 로고
    • Expression of CYP3A, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human hepatocyte
    • Drocourt L, Ourlin JC, Pascussi JM, Maurel P, Vilarem MJ. Expression of CYP3A, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human hepatocyte. J Biol Chem. 2002 ; 277: 25125-25132
    • (2002) J Biol Chem , vol.277 , pp. 25125-25132
    • Drocourt, L.1    Ourlin, J.C.2    Pascussi, J.M.3    Maurel, P.4    Vilarem, M.J.5
  • 21
    • 0034691064 scopus 로고    scopus 로고
    • St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor
    • Moore LB, Goodwin B, Jones SA, et al. St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor. Proc Natl Acad Sci U S A. 2000 ; 97: 7500-7502
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 7500-7502
    • Moore, L.B.1    Goodwin, B.2    Jones, S.A.3
  • 22
    • 0042934069 scopus 로고    scopus 로고
    • Avasimibe induces CYP3A4 and multiple drug resistance protein 1 gene expression through activation of the pregnane X receptor
    • Sahi J, Milad MA, Zheng X, et al. Avasimibe induces CYP3A4 and multiple drug resistance protein 1 gene expression through activation of the pregnane X receptor. J Pharmacol Exp Ther. 2003 ; 306: 1027-1034
    • (2003) J Pharmacol Exp Ther , vol.306 , pp. 1027-1034
    • Sahi, J.1    Ma, M.2    Zheng, X.3
  • 23
    • 0035201366 scopus 로고    scopus 로고
    • Rifampin is a selective, pleiotropic inducer of drug metabolism genes in human hepatocytes: Studies with cDNA and oligonucleotide expression arrays
    • Rae JM, Johnson MD, Lippman ME, Flockhart DA. Rifampin is a selective, pleiotropic inducer of drug metabolism genes in human hepatocytes: studies with cDNA and oligonucleotide expression arrays. J Pharmacol Exp Ther. 2001 ; 299: 849-857
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 849-857
    • Rae, J.M.1    Johnson, M.D.2    Lippman, M.E.3    Flockhart, D.A.4
  • 24
    • 0035336558 scopus 로고    scopus 로고
    • Pharmacokinetic and prognostic significance of intestinal MDR1 expression in recipients of living-donor liver transplantation
    • Hashida T, Masuda S, Uemoto S, Saito H, Tanaka K, Inui K. Pharmacokinetic and prognostic significance of intestinal MDR1 expression in recipients of living-donor liver transplantation. Clin Pharmacol Ther. 2001 ; 69: 308-316
    • (2001) Clin Pharmacol Ther , vol.69 , pp. 308-316
    • Hashida, T.1    Masuda, S.2    Uemoto, S.3    Saito, H.4    Tanaka, K.5    Inui, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.