-
1
-
-
0141799911
-
Defensins: Antimicrobial peptides of innate immunity
-
Ganz, T. Defensins: Antimicrobial peptides of innate immunity. Nat. Rev. Immunol. 2003, 3, 710-720.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 710-720
-
-
Ganz, T.1
-
3
-
-
14544282377
-
Antimicrobial peptides: Pore formers or metabolic inhibitors in bacteria? Nat
-
Brogden, K.A. Antimicrobial peptides: Pore formers or metabolic inhibitors in bacteria? Nat. Rev. Microbiol. 2005, 3, 238-250.
-
(2005)
Rev. Microbiol.
, vol.3
, pp. 238-250
-
-
Brogden, K.A.1
-
4
-
-
79151473786
-
Defensins in innate immunity
-
Hazlett, L.; Wu, M. Defensins in innate immunity. Cell Tissue Res. 2011, 343, 175-188.
-
(2011)
Cell Tissue Res
, vol.343
, pp. 175-188
-
-
Hazlett, L.1
Wu, M.2
-
5
-
-
0344483901
-
Production of β-defensin antimicrobial peptides by the oral mucosa and salivary glands
-
Mathews, M.; Jia, H.P.; Guthmiller, J.M.; Losh, G.; Graham, S.; Johnson, G.K.; Tack, B.F.; McCray, P.B. Production of β-defensin antimicrobial peptides by the oral mucosa and salivary glands. Infect. Immun. 1999, 67, 2740-2745.
-
(1999)
Infect. Immun.
, vol.67
, pp. 2740-2745
-
-
Mathews, M.1
Jia, H.P.2
Guthmiller, J.M.3
Losh, G.4
Graham, S.5
Johnson, G.K.6
Tack, B.F.7
McCray, P.B.8
-
6
-
-
37249084758
-
Role of β-defensins in oral epithelial health and disease
-
Abiko, Y.; Saitoh, M.; Nishimura, M.; Yamazaki, M.; Sawamura, D.; Kaku, T. Role of β-defensins in oral epithelial health and disease. Med. Mol. Morphol. 2007, 40, 179-184.
-
(2007)
Med. Mol. Morphol.
, vol.40
, pp. 179-184
-
-
Abiko, Y.1
Saitoh, M.2
Nishimura, M.3
Yamazaki, M.4
Sawamura, D.5
Kaku, T.6
-
7
-
-
54149110348
-
Nuclear hBD-1 accumulation in malignant salivary gland tumors
-
doi:10.1186/1471-2407-8-290
-
Wenghoefer, M.; Pantelis, A.; Dommisch, H.; Götz, W.; Reich, R.; Bergé, S.; Martini, M.; Allam, J.P.; Jepsen, S.; Merkelbach-Bruse, S.; Fischer, HP.; Novak, N.; Winter, J. Nuclear hBD-1 accumulation in malignant salivary gland tumors. BMC Cancer 2008, 8, doi:10.1186/1471-2407-8-290.
-
(2008)
BMC Cancer
, vol.8
-
-
Wenghoefer, M.1
Pantelis, A.2
Dommisch, H.3
Götz, W.4
Reich, R.5
Bergé, S.6
Martini, M.7
Allam, J.P.8
Jepsen, S.9
Merkelbach-Bruse, S.10
Fischer, H.P.11
Novak, N.12
Winter, J.13
-
8
-
-
67349219387
-
Down regulation and nuclear localization of human beta-defensin-1 in pleomorphic adenomas of salivary glands
-
Pantelis, A.; Wenghoefer, M.; Haas, S.; Merkelbach-Bruse, S.; Pantelis, D.; Jepsen, S.; Bootz, F.; Winter, J. Down regulation and nuclear localization of human beta-defensin-1 in pleomorphic adenomas of salivary glands. Oral Oncol. 2009, 45, 526-530.
-
(2009)
Oral Oncol
, vol.45
, pp. 526-530
-
-
Pantelis, A.1
Wenghoefer, M.2
Haas, S.3
Merkelbach-Bruse, S.4
Pantelis, D.5
Jepsen, S.6
Bootz, F.7
Winter, J.8
-
9
-
-
32844470378
-
Innate immunity in human bone
-
Warnke, P.H.; Springer, I.N.; Russo, P.A.J.; Wiltfang, J.; Essig, H.; Kosmahl, M.; Sherry, E.; Acil, Y. Innate immunity in human bone. Bone 2006, 38, 400-408.
-
(2006)
Bone
, vol.38
, pp. 400-408
-
-
Warnke, P.H.1
Springer, I.N.2
Russo, P.A.J.3
Wiltfang, J.4
Essig, H.5
Kosmahl, M.6
Sherry, E.7
Acil, Y.8
-
10
-
-
0028981702
-
hBD-1: A novel beta-defensin from human plasma
-
Bensch, K.W.; Raida, M.; Mägert, H.J.; Schulz-Knappe, P.; Forssmann, W.G. hBD-1: A novel beta-defensin from human plasma. FEBS Lett. 1995, 368, 331-335.
-
(1995)
FEBS Lett
, vol.368
, pp. 331-335
-
-
Bensch, K.W.1
Raida, M.2
Mägert, H.J.3
Schulz-Knappe, P.4
Forssmann, W.G.5
-
11
-
-
0030820726
-
A peptide antibiotic from human skin
-
Harder, J.; Bartels, J.; Christophers, E.; Schröder, J.M. A peptide antibiotic from human skin. Nature 1997, 387, 861.
-
(1997)
Nature
, vol.387
, pp. 861
-
-
Harder, J.1
Bartels, J.2
Christophers, E.3
Schröder, J.M.4
-
12
-
-
0035937107
-
Isolation and characterization of human β-defensin-3, a novel human inducible peptide antibiotic
-
Harder, J.; Bartels, J.; Christophers, E.; Schröder, J.M. Isolation and characterization of human β-defensin-3, a novel human inducible peptide antibiotic. J. Biol. Chem. 2001, 276, 5707-5713.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 5707-5713
-
-
Harder, J.1
Bartels, J.2
Christophers, E.3
Schröder, J.M.4
-
13
-
-
80051595909
-
Increased human defensine levels hint at an inflammatory etiology of bisphosphonate-associated osteonecrosis of the jaw: An immunohistological study
-
doi:10.1186/1479-5876-9-135
-
Stockmann, P.; Wehrhan, F.; Schwarz-Furlan, S.; Stelzle, F.; Trabert, S.; Neukam, F.W.; Nkenke, E. Increased human defensine levels hint at an inflammatory etiology of bisphosphonate-associated osteonecrosis of the jaw: An immunohistological study. J. Transl. Med. 2011, 9, doi:10.1186/1479-5876-9-135.
-
(2011)
J. Transl. Med.
, vol.9
-
-
Stockmann, P.1
Wehrhan, F.2
Schwarz-Furlan, S.3
Stelzle, F.4
Trabert, S.5
Neukam, F.W.6
Nkenke, E.7
-
14
-
-
69249158954
-
Human defensins activate monocyte-derived dendritic cells, promote the production of proinflammatory cytokines, and up-regulate the surface expression of CD91
-
Presicce, P.; Giannelli, S.; Taddeo, A.; Villa, M.L.; Della Bella, S. Human defensins activate monocyte-derived dendritic cells, promote the production of proinflammatory cytokines, and up-regulate the surface expression of CD91. J. Leukoc. Biol. 2009, 86, 941-948.
-
(2009)
J. Leukoc. Biol.
, vol.86
, pp. 941-948
-
-
Presicce, P.1
Giannelli, S.2
Taddeo, A.3
Villa, M.L.4
Della Bella, S.5
-
15
-
-
84155174651
-
Human. β-defensins differently affect proliferation, differentiation, and mineralization of osteoblast-like MG63 cells
-
doi: 10.1002/jcp.22808
-
Kraus, D.; Deschner, J.; Jäger, A.; Wenghoefer, M.; Bayer, S.; Jepsen, S.; Allam, J.; Novak, N.; Meyer, R.; Winter, J. Human β-defensins differently affect proliferation, differentiation, and mineralization of osteoblast-like MG63 cells. J. Cell. Physiol. 2011, doi: 10.1002/jcp.22808.
-
(2011)
J. Cell. Physiol.
-
-
Kraus, D.1
Deschner, J.2
Jäger, A.3
Wenghoefer, M.4
Bayer, S.5
Jepsen, S.6
Allam, J.7
Novak, N.8
Meyer, R.9
Winter, J.10
-
16
-
-
79951653955
-
Human beta-defensin-1, -2, and -3 exhibit opposite effects on oral squamous cell carcinoma cell proliferation
-
Winter, J.; Pantelis, A.; Reich, R.; Martini, M.; Kraus, D.; Jepsen, S.; Allam, J.P.; Novak, N.; Wenghoefer, M. Human beta-defensin-1, -2, and -3 exhibit opposite effects on oral squamous cell carcinoma cell proliferation. Cancer Invest. 2011, 29, 196-201.
-
(2011)
Cancer Invest
, vol.29
, pp. 196-201
-
-
Winter, J.1
Pantelis, A.2
Reich, R.3
Martini, M.4
Kraus, D.5
Jepsen, S.6
Allam, J.P.7
Novak, N.8
Wenghoefer, M.9
-
17
-
-
0033569408
-
Beta-defensins: Linking innate and adaptive immunity through dendritic and T cell CCR6
-
Yang, D.; Chertov, O. Bykovskaia, S.N.; Chen, Q.; Buffo, M.J.; Shogan, J.; Anderson, M.; Schröder, J.M.; Wang, J.M.; Howard, O.M.; Oppenheim, J.J. Beta-defensins: Linking innate and adaptive immunity through dendritic and T cell CCR6. Science 1999, 286, 525-528.
-
(1999)
Science
, vol.286
, pp. 525-528
-
-
Yang, D.1
Chertov, O.2
Bykovskaia, S.N.3
Chen, Q.4
Buffo, M.J.5
Shogan, J.6
Anderson, M.7
Schröder, J.M.8
Wang, J.M.9
Howard, O.M.10
Oppenheim, J.J.11
-
18
-
-
0036829687
-
Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2
-
Biragyn, A.; Ruffini, P.A.; Leifer, C.A.; Klyushnenkova, E.; Shakhov, A.; Chertov, O.; Shirakawa, A.K.; Farber, J.M.; Segal, D.M.; Oppenheim, J.J.; Kwak, L.W. Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2. Science 2002, 298, 1025-1029.
-
(2002)
Science
, vol.298
, pp. 1025-1029
-
-
Biragyn, A.1
Ruffini, P.A.2
Leifer, C.A.3
Klyushnenkova, E.4
Shakhov, A.5
Chertov, O.6
Shirakawa, A.K.7
Farber, J.M.8
Segal, D.M.9
Oppenheim, J.J.10
Kwak, L.W.11
-
19
-
-
0742290129
-
Neutrophil defensins enhance lung epithelial wound closure and mucin gene expression in vitro
-
Aarbiou, J.; Verhoosel, R.M.; van Wetering, S.; De Boer, W.I.; van Krieken, J.H.; Litvinov, S.V.; Rabe, K.F.; Hiemstra, P.S. Neutrophil defensins enhance lung epithelial wound closure and mucin gene expression in vitro. Am. J. Respir. Cell Mol. Biol. 2004, 30, 193-201.
-
(2004)
Am. J. Respir. Cell Mol. Biol.
, vol.30
, pp. 193-201
-
-
Aarbiou, J.1
Verhoosel, R.M.2
van Wetering, S.3
De Boer, W.I.4
van Krieken, J.H.5
Litvinov, S.V.6
Rabe, K.F.7
Hiemstra, P.S.8
-
20
-
-
33847040438
-
Antimicrobial peptides human beta-defensins stimulate epidermal keratinocyte migration, proliferation and production of proinflammatory cytokines and chemokines
-
Niyonsaba, F.; Ushio, H.; Nakano, N.; Ng, W.; Sayama, K.; Hashimoto, K.; Nagaoka, I.; Okumura, K.; Ogawa, H. Antimicrobial peptides human beta-defensins stimulate epidermal keratinocyte migration, proliferation and production of proinflammatory cytokines and chemokines. J. Invest. Dermatol. 2007, 127, 594-604.
-
(2007)
J. Invest. Dermatol.
, vol.127
, pp. 594-604
-
-
Niyonsaba, F.1
Ushio, H.2
Nakano, N.3
Ng, W.4
Sayama, K.5
Hashimoto, K.6
Nagaoka, I.7
Okumura, K.8
Ogawa, H.9
-
21
-
-
79960691993
-
A common mutation in the defensin DEFB126 causes impaired sperm function and subfertility
-
doi: 10.1126/ scitranslmed.3002289
-
Tollner, T.L.; Venners, S.A.; Hollox, E.J.; Yudin, A.I.; Liu, X.; Tang, G.; Xing, H.; Kays, R.J.; Lau, T.; Overstreet, J.W.; Xu, X.; Bevins, C.L.; Cherr, G.N. A common mutation in the defensin DEFB126 causes impaired sperm function and subfertility. Sci. Transl. Med. 2011, 3, doi: 10.1126/ scitranslmed.3002289.
-
(2011)
Sci. Transl. Med.
, vol.3
-
-
Tollner, T.L.1
Venners, S.A.2
Hollox, E.J.3
Yudin, A.I.4
Liu, X.5
Tang, G.6
Xing, H.7
Kays, R.J.8
Lau, T.9
Overstreet, J.W.10
Xu, X.11
Bevins, C.L.12
Cherr, G.N.13
-
22
-
-
0022402545
-
Defensins
-
Ganz, T.; Selsted, M.E.; Szklarek, D.; Harwig, S.S.L.; Daher, K.; Bainton, D.F.; Lehrer, R.I. Defensins. J. Clin. Invest. 1985, 76, 1427-1435.
-
(1985)
J. Clin. Invest.
, vol.76
, pp. 1427-1435
-
-
Ganz, T.1
Selsted, M.E.2
Szklarek, D.3
Harwig, S.S.L.4
Daher, K.5
Bainton, D.F.6
Lehrer, R.I.7
-
23
-
-
0026660392
-
Enteric defensins: Antibiotic peptide components of intestinal host defense
-
Selsted, M.E.; Miller, S.I.; Henschen, A.H.; Quellette, A.J. Enteric defensins: Antibiotic peptide components of intestinal host defense. J. Cell Biol. 1992, 118, 929-936.
-
(1992)
J. Cell Biol.
, vol.118
, pp. 929-936
-
-
Selsted, M.E.1
Miller, S.I.2
Henschen, A.H.3
Quellette, A.J.4
-
24
-
-
0027390031
-
Defensin-6 mRNA in human Paneth cells: Implication for antimicrobial peptides in host defense of the human bowel
-
Jones, D.E.; Bevins, C.L. Defensin-6 mRNA in human Paneth cells: Implication for antimicrobial peptides in host defense of the human bowel. FEBS Lett. 1993, 315, 187-192.
-
(1993)
FEBS Lett
, vol.315
, pp. 187-192
-
-
Jones, D.E.1
Bevins, C.L.2
-
25
-
-
11244342346
-
Antibacterial activity and specificity of the six human alpha-defensins
-
Ericksen, B.; Wu, Z.; Lu, W.; Lehrer, R.I. Antibacterial activity and specificity of the six human alpha-defensins. Antimicrob. Agents Chemother. 2005, 49, 269-275.
-
(2005)
Antimicrob. Agents Chemother.
, vol.49
, pp. 269-275
-
-
Ericksen, B.1
Wu, Z.2
Lu, W.3
Lehrer, R.I.4
-
26
-
-
0033927825
-
Antibacterial activity of human neutrophil peptide 1 against Mycobacterium tuberculosis H37Rv: In vitro and ex vivo study
-
Sharma, S.; Verma, I.; Khuller, GK. Antibacterial activity of human neutrophil peptide 1 against Mycobacterium tuberculosis H37Rv: In vitro and ex vivo study. Eur. Respir. J. 2000, 16, 112-117.
-
(2000)
Eur. Respir. J.
, vol.16
, pp. 112-117
-
-
Sharma, S.1
Verma, I.2
Khuller, G.K.3
-
27
-
-
0035139564
-
Therapeutic potential of human neutrophil peptide 1 against experimental tuberculosis
-
Sharma, S.; Verma, I.; Khuller, GK. Therapeutic potential of human neutrophil peptide 1 against experimental tuberculosis. Antimicrob. Agents Chemother. 2001, 45, 639-640.
-
(2001)
Antimicrob. Agents Chemother.
, vol.45
, pp. 639-640
-
-
Sharma, S.1
Verma, I.2
Khuller, G.K.3
-
28
-
-
36448983978
-
Defensins: Antimicrobial peptides for therapeutic development
-
Verma, C.; Seebah, S.; Low, S.M.; Zhou, L.; Liu, S.P.; Li, J.; Beuerman, R.W. Defensins: Antimicrobial peptides for therapeutic development. Biotechnol. J. 2007, 2, 1353-1359.
-
(2007)
Biotechnol. J.
, vol.2
, pp. 1353-1359
-
-
Verma, C.1
Seebah, S.2
Low, S.M.3
Zhou, L.4
Liu, S.P.5
Li, J.6
Beuerman, R.W.7
-
29
-
-
33845401745
-
Human alpha- and beta-defensins block multiple steps in herpes simplex virus infection
-
Hazrati, E.; Galen, B.; Lu, W.; Wang, W.; Ouyang, Y.; Keller, M.J.; Lehrer, R.I.; Herold, B.C. Human alpha- and beta-defensins block multiple steps in herpes simplex virus infection. J. Immunol. 2006, 177, 8658-8666.
-
(2006)
J. Immunol.
, vol.177
, pp. 8658-8666
-
-
Hazrati, E.1
Galen, B.2
Lu, W.3
Wang, W.4
Ouyang, Y.5
Keller, M.J.6
Lehrer, R.I.7
Herold, B.C.8
-
30
-
-
2942729771
-
Activity of alpha- and theta-defensins against primary isolates of HIV-1
-
Wang, W.; Owen, S.M.; Rudolph, D.L.; Cole, A.M.; Hong, T.; Waring, A.J.; Lal, R.B.; Lehrer, R.I. Activity of alpha- and theta-defensins against primary isolates of HIV-1. J. Immunol. 2004, 173, 515-520.
-
(2004)
J. Immunol.
, vol.173
, pp. 515-520
-
-
Wang, W.1
Owen, S.M.2
Rudolph, D.L.3
Cole, A.M.4
Hong, T.5
Waring, A.J.6
Lal, R.B.7
Lehrer, R.I.8
-
31
-
-
0142093583
-
Alpha-defensins can have anti-HIV activity but are not CD8 cell anti-HIV factors. AIDS 2003 26 F23-F32
-
Mackewicz, C.E.; Yuan, J.; Tran, P.; Diaz, L.; Mack, E.; Selsted, M.E.; Levy, J.A. Alpha-defensins can have anti-HIV activity but are not CD8 cell anti-HIV factors. AIDS 2003, 26, F23-F32. Erratum in: AIDS 2003, 26, F31.
-
(2003)
Erratum in: AIDS
, vol.26
-
-
Mackewicz, C.E.1
Yuan, J.2
Tran, P.3
Diaz, L.4
Mack, E.5
Selsted, M.E.6
Levy, J.A.7
-
32
-
-
14644425916
-
Dual role of alpha-defensin-1 in anti-HIV-1 innate immunity
-
Chang, T.L.; Vargas, J., Jr.; DelPortillo, A.; Klotman, M.E. Dual role of alpha-defensin-1 in anti-HIV-1 innate immunity. J. Clin. Invest. 2005, 115, 765-773.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 765-773
-
-
Chang, T.L.1
Vargas Jr., J.2
DelPortillo, A.3
Klotman, M.E.4
-
33
-
-
2342573669
-
Theta defensins protect cells from infection by herpes simplex virus by inhibiting viral adhesion and entry
-
Yasin, B.; Wang, W.; Pang, M.; Cheshenko, N.; Hong, T.; Waring, A.J.; Herold, B.C.; Wagar, E.A.; Lehrer, R.I. Theta defensins protect cells from infection by herpes simplex virus by inhibiting viral adhesion and entry. J. Virol. 2004, 78, 5147-5156.
-
(2004)
J. Virol.
, vol.78
, pp. 5147-5156
-
-
Yasin, B.1
Wang, W.2
Pang, M.3
Cheshenko, N.4
Hong, T.5
Waring, A.J.6
Herold, B.C.7
Wagar, E.A.8
Lehrer, R.I.9
-
34
-
-
24644475283
-
Defensins and other antimicrobial peptides at the ocular surface
-
McDermott, A.M. Defensins and other antimicrobial peptides at the ocular surface. Ocul. Surf. 2004, 2, 229-247.
-
(2004)
Ocul. Surf.
, vol.2
, pp. 229-247
-
-
McDermott, A.M.1
-
35
-
-
0026535104
-
Posttranslational processing of defensins in immature human myeloid cells
-
Valore, E.V.; Ganz, T. Posttranslational processing of defensins in immature human myeloid cells. Blood 1992, 79, 1538-1544.
-
(1992)
Blood
, vol.79
, pp. 1538-1544
-
-
Valore, E.V.1
Ganz, T.2
-
37
-
-
0035430147
-
Human beta-defensin 4 A novel inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity
-
García, J.R.; Krause, A.; Schulz, S.; Rodríguez-Jiménez, F.J.; Klüver, E.; Adermann, K.; Forssmann, U.; Frimpong-Boateng, A.; Bals, R.; Forssmann, W.G. Human beta-defensin 4: A novel inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity. FASEB J. 2001, 15, 1819-1821.
-
(2001)
FASEB J
, vol.15
, pp. 1819-1821
-
-
García, J.R.1
Krause, A.2
Schulz, S.3
Rodríguez-Jiménez, F.J.4
Klüver, E.5
Adermann, K.6
Forssmann, U.7
Frimpong-Boateng, A.8
Bals, R.9
Forssmann, W.G.10
-
38
-
-
21744462099
-
Human beta-defensins: Differential activity against Candidal species and regulation by Candida albicans
-
Feng, Z.; Jiang, B.; Chandra, J.; Ghannoum, M.; Nelson, S.; Weinberg, A. Human beta-defensins: Differential activity against Candidal species and regulation by Candida albicans. J. Dent. Res. 2005, 84, 445-450.
-
(2005)
J. Dent. Res.
, vol.84
, pp. 445-450
-
-
Feng, Z.1
Jiang, B.2
Chandra, J.3
Ghannoum, M.4
Nelson, S.5
Weinberg, A.6
-
39
-
-
17044440150
-
Correlation between beta-defensin expression and induction profiles in gingival keratinocytes
-
Joly, S.; Organ, C.C.; Johnson, G.K.; McCray, P.B.; Guthmiller, J.M. Correlation between beta-defensin expression and induction profiles in gingival keratinocytes. Mol. Immunol. 2005, 42, 1073-1084.
-
(2005)
Mol. Immunol.
, vol.42
, pp. 1073-1084
-
-
Joly, S.1
Organ, C.C.2
Johnson, G.K.3
McCray, P.B.4
Guthmiller, J.M.5
-
40
-
-
9144240994
-
Human epithelial beta-defensins 2 and 3 inhibit HIV-1 replication
-
Quiñones-Mateu, M.E.; Lederman, M.M.; Feng, Z.; Chakraborty, B.; Weber, J.; Rangel, H.R.; Marotta, M.L.; Mirza, M.; Jiang, B.; Kiser, P.; Medvik, K.; Sieg, S.F.; Weinberg, A. Human epithelial beta-defensins 2 and 3 inhibit HIV-1 replication. AIDS 2003, 17, F39-F48.
-
(2003)
AIDS
, vol.17
-
-
Quiñones-Mateu, M.E.1
Lederman, M.M.2
Feng, Z.3
Chakraborty, B.4
Weber, J.5
Rangel, H.R.6
Marotta, M.L.7
Mirza, M.8
Jiang, B.9
Kiser, P.10
Medvik, K.11
Sieg, S.F.12
Weinberg, A.13
-
41
-
-
27644571478
-
Human beta-defensins suppress human immunodeficiency virus infection: Potential role in mucosal protection
-
Sun, L.; Finnegan, C.M.; Kish-Catalone, T.; Blumenthal, R.; Garzino-Demo, P.; La Terra Maggiore, G.M.; Berrone, S.; Kleinman, C.; Wu, Z.; Abdelwahab, S.; Lu, W.; Garzino-Demo, A. Human beta-defensins suppress human immunodeficiency virus infection: Potential role in mucosal protection. J. Virol. 2005, 79, 14318-14329.
-
(2005)
J. Virol.
, vol.79
, pp. 14318-14329
-
-
Sun, L.1
Finnegan, C.M.2
Kish-Catalone, T.3
Blumenthal, R.4
Garzino-Demo, P.5
La Terra Maggiore, G.M.6
Berrone, S.7
Kleinman, C.8
Wu, Z.9
Abdelwahab, S.10
Lu, W.11
Garzino-Demo, A.12
-
42
-
-
0030855146
-
Protegrin-1: A broad-spectrum, rapidly microbicidal peptide with in vivo activity
-
Steinberg, D.A.; Hurst, M.A.; Fujii, C.A.; Kung, A.H.; Ho, J.F.; Cheng, C.; Loury, D.J.; Fiddess, J.C. Protegrin-1: A broad-spectrum, rapidly microbicidal peptide with in vivo activity. Antimicrob. Agents Chemother. 1997, 41, 1738-1742.
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 1738-1742
-
-
Steinberg, D.A.1
Hurst, M.A.2
Fujii, C.A.3
Kung, A.H.4
Ho, J.F.5
Cheng, C.6
Loury, D.J.7
Fiddess, J.C.8
-
43
-
-
0032942727
-
In vitro antibacterial properties of pexiganan, an analog of magainin
-
Ge, Y.D.; MacDonald, D.L.; Holroyd, K.J.; Thornsberry, C.; Wexler, H.; Zasloff, M. In vitro antibacterial properties of pexiganan, an analog of magainin. Antimicrob. Agents Chemother. 1999, 43, 782-788.
-
(1999)
Antimicrob. Agents Chemother.
, vol.43
, pp. 782-788
-
-
Ge, Y.D.1
MacDonald, D.L.2
Holroyd, K.J.3
Thornsberry, C.4
Wexler, H.5
Zasloff, M.6
-
44
-
-
21444442023
-
Antimicrobial peptide therapeutics for cystic fibrosis
-
Zhang, L.; Parente, J.; Harris, S.M.; Woods, D.E.; Hancock, E.W.; Falla, T.J. Antimicrobial peptide therapeutics for cystic fibrosis. Antimicrob. Agents Chemother. 2005, 49, 2921-2927.
-
(2005)
Antimicrob. Agents Chemother.
, vol.49
, pp. 2921-2927
-
-
Zhang, L.1
Parente, J.2
Harris, S.M.3
Woods, D.E.4
Hancock, E.W.5
Falla, T.J.6
-
45
-
-
0023161695
-
Defensins mediate the microbicidal activity of human neutrophil granule extract against Acinetobacter calcoaceticus
-
Greenwald, G.I.; Ganz, T. Defensins mediate the microbicidal activity of human neutrophil granule extract against Acinetobacter calcoaceticus. Infect. Immun. 1987, 55, 1365-1368.
-
(1987)
Infect. Immun.
, vol.55
, pp. 1365-1368
-
-
Greenwald, G.I.1
Ganz, T.2
-
46
-
-
0034125829
-
Mucoid Pseudomonas aeroginosa, TNF-alpha, and IL-1beta, but not IL-6, induce human beta-defensin-2 in respiratory epithelia
-
Harder, J.; Meyer-Hoffert, U.; Teran, L.M.; Schwichtenberg, L.; Bartels, J.; Maune, S.; Schröder, J.M. Mucoid Pseudomonas aeroginosa, TNF-alpha, and IL-1beta, but not IL-6, induce human beta-defensin-2 in respiratory epithelia. Am. J. Respir. Cell Mol. Biol. 2000, 22, 714-721.
-
(2000)
Am. J. Respir. Cell Mol. Biol.
, vol.22
, pp. 714-721
-
-
Harder, J.1
Meyer-Hoffert, U.2
Teran, L.M.3
Schwichtenberg, L.4
Bartels, J.5
Maune, S.6
Schröder, J.M.7
-
47
-
-
0035941493
-
Discovery of new human b-defensins using a genomics-based approach
-
Jia, H.P.; Schutte, B.C.; Schudy, A.; Linzmeier, R.; Guthmiller, J.M.; Johnson, G.K.; Tack, B.F.; Mitros, J.P.; Rosenthal, A.; Ganz, T. Discovery of new human b-defensins using a genomics-based approach. Gene 2001, 263, 211-218.
-
(2001)
Gene
, vol.263
, pp. 211-218
-
-
Jia, H.P.1
Schutte, B.C.2
Schudy, A.3
Linzmeier, R.4
Guthmiller, J.M.5
Johnson, G.K.6
Tack, B.F.7
Mitros, J.P.8
Rosenthal, A.9
Ganz, T.10
-
48
-
-
0036040263
-
Expression of beta-defensin 1 and 2 mRNA by human monocytes, macrophages and dendritic cells
-
Duits, L.A.; Ravensbergen, B.; Rademaker, M.; Hiemstra, P.S.; Nibbering, P.H. Expression of beta-defensin 1 and 2 mRNA by human monocytes, macrophages and dendritic cells. Immunology 2002, 106, 517-525.
-
(2002)
Immunology
, vol.106
, pp. 517-525
-
-
Duits, L.A.1
Ravensbergen, B.2
Rademaker, M.3
Hiemstra, P.S.4
Nibbering, P.H.5
-
49
-
-
33746889083
-
Induction of beta-defensin 3 in keratinocytes stimulated by bacterial lipopeptides through toll-like receptor 2
-
Sumikawa, Y.; Asada, H.; Hoshino, K.; Azukizawa, H.; Katayama, I.; Akira, S.; Itami, S. Induction of beta-defensin 3 in keratinocytes stimulated by bacterial lipopeptides through toll-like receptor 2. Microbes Infect. 2006, 8, 1513-1521.
-
(2006)
Microbes Infect
, vol.8
, pp. 1513-1521
-
-
Sumikawa, Y.1
Asada, H.2
Hoshino, K.3
Azukizawa, H.4
Katayama, I.5
Akira, S.6
Itami, S.7
-
50
-
-
4444340990
-
Direct bacterial protein PAMP recognition by human NK cells involves TLRs and triggers alpha-defensin production
-
Chalifour, A.; Jeannin, P.; Gauchat, J.F.; Blaecke, A.; Malissard, M.; N'Guyen, T.; Thieblemont, N.; Delneste, Y. Direct bacterial protein PAMP recognition by human NK cells involves TLRs and triggers alpha-defensin production. Blood 2004, 104, 1778-1783.
-
(2004)
Blood
, vol.104
, pp. 1778-1783
-
-
Chalifour, A.1
Jeannin, P.2
Gauchat, J.F.3
Blaecke, A.4
Malissard, M.5
N'Guyen, T.6
Thieblemont, N.7
Delneste, Y.8
-
51
-
-
7244257312
-
NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression
-
Wehkamp, J.; Harder, J.; Weichenthal, M.; Schwab, M.; Schäffeler, E.; Schlee, M.; Herrlinger, K.R.; Stallmach, A.; Noack, F.; Fritz, P.; Schröder, J.M.; Bevins, C.L.; Fellermann, K.; Stange, E.F. NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression. Gut 2004, 53, 1658-1664.
-
(2004)
Gut
, vol.53
, pp. 1658-1664
-
-
Wehkamp, J.1
Harder, J.2
Weichenthal, M.3
Schwab, M.4
Schäffeler, E.5
Schlee, M.6
Herrlinger, K.R.7
Stallmach, A.8
Noack, F.9
Fritz, P.10
Schröder, J.M.11
Bevins, C.L.12
Fellermann, K.13
Stange, E.F.14
-
52
-
-
74549193899
-
Differential modulation of human beta-defensins expression in human gingival epithelia by Porphyromonas gingivalis lipopolysaccharide with tetra- and penta-acylated lipid A structures
-
Lu, Q.; Darveau, R.P.; Samaranayake, L.P.; Wang, C.Y.; Jin, L. Differential modulation of human beta-defensins expression in human gingival epithelia by Porphyromonas gingivalis lipopolysaccharide with tetra- and penta-acylated lipid A structures. Innate Immun. 2009, 15, 325-335.
-
(2009)
Innate Immun
, vol.15
, pp. 325-335
-
-
Lu, Q.1
Darveau, R.P.2
Samaranayake, L.P.3
Wang, C.Y.4
Jin, L.5
-
53
-
-
58149354657
-
Osteoblasts participate in the innate immunity of the bone by producing human beta defensin-3
-
Varoga, D.; Wruck, C.J.; Tohidnezhad, M.; Brandenburg, L.; Paulsen, F.; Mentlein, R.; Seekamp, A.; Besch, L.; Pufe, T. Osteoblasts participate in the innate immunity of the bone by producing human beta defensin-3. Histochem. Cell Biol. 2009, 131, 207-218.
-
(2009)
Histochem. Cell Biol.
, vol.131
, pp. 207-218
-
-
Varoga, D.1
Wruck, C.J.2
Tohidnezhad, M.3
Brandenburg, L.4
Paulsen, F.5
Mentlein, R.6
Seekamp, A.7
Besch, L.8
Pufe, T.9
-
54
-
-
0034650823
-
Cutting edge: Cationic antimicrobial peptides block the binding of lipopolysaccharide (LPS) to LPS binding protein
-
Scott, M.G.; Vreugdenhil, A.C.; Buurman, W.A.; Hancock, R.E.; Gold, M.R. Cutting edge: Cationic antimicrobial peptides block the binding of lipopolysaccharide (LPS) to LPS binding protein. J. Immunol. 2000, 164, 549-553.
-
(2000)
J. Immunol.
, vol.164
, pp. 549-553
-
-
Scott, M.G.1
Vreugdenhil, A.C.2
Buurman, W.A.3
Hancock, R.E.4
Gold, M.R.5
-
55
-
-
68149125185
-
Dying and necrotic neutrophils are anti-inflammatory secondary to the release of alpha-defensins
-
Miles, K.; Clarke, D.J.; Lu, W.; Sibinska, Z.; Beaumont, P.E.; Davidson, D.J.; Barr, T.A.; Campopiano, D.J.; Gray, M. Dying and necrotic neutrophils are anti-inflammatory secondary to the release of alpha-defensins. J. Immunol. 2009, 183, 2122-2132.
-
(2009)
J. Immunol.
, vol.183
, pp. 2122-2132
-
-
Miles, K.1
Clarke, D.J.2
Lu, W.3
Sibinska, Z.4
Beaumont, P.E.5
Davidson, D.J.6
Barr, T.A.7
Campopiano, D.J.8
Gray, M.9
-
56
-
-
55849130745
-
Neutrophil primary granule proteins HBP and HNP1-3 boost bacterial phagocytosis by human and murine macrophages
-
Soehnlein, O.; Kai-Larsen, Y.; Frithiof, R.; Sorensen, O.E.; Kenne, E.; Scharffetter-Kochanek, K.; Eriksson, E.E.; Herwald, H.; Agerberth, B.; Lindblom, L. Neutrophil primary granule proteins HBP and HNP1-3 boost bacterial phagocytosis by human and murine macrophages. J. Clin. Invest. 2008, 118, 3491-3502.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3491-3502
-
-
Soehnlein, O.1
Kai-Larsen, Y.2
Frithiof, R.3
Sorensen, O.E.4
Kenne, E.5
Scharffetter-Kochanek, K.6
Eriksson, E.E.7
Herwald, H.8
Agerberth, B.9
Lindblom, L.10
-
57
-
-
41149111364
-
Evaluation of the effect of human beta-defensins on neutrophil apoptosis
-
Nagaoka, I.; Niyonsaba, F.; Tsutsumi-Ishii, Y.; Tamura, H.; Hirata, M. Evaluation of the effect of human beta-defensins on neutrophil apoptosis. Int. Immunol. 2008, 20, 543-553.
-
(2008)
Int. Immunol.
, vol.20
, pp. 543-553
-
-
Nagaoka, I.1
Niyonsaba, F.2
Tsutsumi-Ishii, Y.3
Tamura, H.4
Hirata, M.5
-
58
-
-
20544442905
-
Alarmins: Chemotatctic activators of immune response
-
Oppenheim, J.J.; Yang, D. Alarmins: Chemotatctic activators of immune response. Curr. Opin. Immunol. 2005, 17, 359-365.
-
(2005)
Curr. Opin. Immunol.
, vol.17
, pp. 359-365
-
-
Oppenheim, J.J.1
Yang, D.2
-
59
-
-
0036208192
-
Epithelial cell-derived human beta-defensin-2 acts as a chemotaxin for mast cells through a pertussis toxin-sensitive and phospholipase C-dependent pathway
-
Niyonsaba, F.; Iwabuchi, K.; Matsuda, H.; Ogawa, H.; Nagaoka, I. Epithelial cell-derived human beta-defensin-2 acts as a chemotaxin for mast cells through a pertussis toxin-sensitive and phospholipase C-dependent pathway. Int. Immunol. 2002, 14, 421-426.
-
(2002)
Int. Immunol.
, vol.14
, pp. 421-426
-
-
Niyonsaba, F.1
Iwabuchi, K.2
Matsuda, H.3
Ogawa, H.4
Nagaoka, I.5
-
60
-
-
1642318503
-
Human beta-defensin-2 functions as a chemotactic agent for tumor necrosis factor-alpha-treated human neutrophils
-
Niyonsaba, F.; Ogawa, H.; Nagaoka, I. Human beta-defensin-2 functions as a chemotactic agent for tumor necrosis factor-alpha-treated human neutrophils. Immunology 2004, 111, 273-281.
-
(2004)
Immunology
, vol.111
, pp. 273-281
-
-
Niyonsaba, F.1
Ogawa, H.2
Nagaoka, I.3
-
61
-
-
0024797674
-
Monocyte-chemotactic activity of defensins from human neutrophils
-
Territo, M.C.; Ganz, T.; Selsted, M.E.; Lehrer, R.I. Monocyte-chemotactic activity of defensins from human neutrophils. J. Clin. Invest. 1989, 84, 2017-2020.
-
(1989)
J. Clin. Invest.
, vol.84
, pp. 2017-2020
-
-
Territo, M.C.1
Ganz, T.2
Selsted, M.E.3
Lehrer, R.I.4
-
62
-
-
0033844287
-
Human neutrophil defensins selectively chemoattract naive T and immature dendritic cells
-
Yang, D.; Chen, Q.; Chertov, O.; Oppenheim, J.J. Human neutrophil defensins selectively chemoattract naive T and immature dendritic cells. J. Leukoc. Biol. 2000, 68, 9-14.
-
(2000)
J. Leukoc. Biol.
, vol.68
, pp. 9-14
-
-
Yang, D.1
Chen, Q.2
Chertov, O.3
Oppenheim, J.J.4
-
63
-
-
0034998629
-
Participation of mammalian defensins and cathelicidins in anti-microbial immunity: Receptors and activities of human defensins and cathelicidin (LL-37)
-
Yang, D.; Chertov, O.; Oppenheim, J.J. Participation of mammalian defensins and cathelicidins in anti-microbial immunity: Receptors and activities of human defensins and cathelicidin (LL-37). J. Leukoc. Biol. 2001, 69, 691-697.
-
(2001)
J. Leukoc. Biol.
, vol.69
, pp. 691-697
-
-
Yang, D.1
Chertov, O.2
Oppenheim, J.J.3
-
64
-
-
77953633456
-
Human β-defensins 2 and 3 and their mouse orthologs induce chemotaxis through interaction with CCR2
-
Rohrl, J.; Yand, D.; Oppenheim, J.J.; Hehlgans, T. Human β-defensins 2 and 3 and their mouse orthologs induce chemotaxis through interaction with CCR2. J. Immunol. 2010, 184, 6688-6694.
-
(2010)
J. Immunol.
, vol.184
, pp. 6688-6694
-
-
Rohrl, J.1
Yand, D.2
Oppenheim, J.J.3
Hehlgans, T.4
-
65
-
-
36749042671
-
Human -defensin-3 activates professional antigen-presenting cells via Toll-like receptors 1 and 2
-
Funderburg, N.; Lederman, M.M.; Feng, Z.; Drage, M.G.; Jadlowsky, J.; Harding, C.V.; Weinberg, A.; Sieg, S.F. Human -defensin-3 activates professional antigen-presenting cells via Toll-like receptors 1 and 2. Proc. Natl. Acad. Sci. USA 2007, 104, 18631-18635.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 18631-18635
-
-
Funderburg, N.1
Lederman, M.M.2
Feng, Z.3
Drage, M.G.4
Jadlowsky, J.5
Harding, C.V.6
Weinberg, A.7
Sieg, S.F.8
-
66
-
-
0033560645
-
Transfer of a cathelicidin peptide antibiotic gene restores bacterial killing in a cystic fibrosis xenograft model J
-
Bals, R.; Weiner, D.J.; Meegalla, R.L.; Wilson, J.M. Transfer of a cathelicidin peptide antibiotic gene restores bacterial killing in a cystic fibrosis xenograft model J. Clin. Invest. 1999, 103, 1113-1117.
-
(1999)
Clin. Invest.
, vol.103
, pp. 1113-1117
-
-
Bals, R.1
Weiner, D.J.2
Meegalla, R.L.3
Wilson, J.M.4
-
67
-
-
26444437111
-
Transient cutaneous adenoviral gene therapy with human host defense peptide hCAP-18/LL-37 is effective fort the treatment of burn wound infections
-
Jacobsen, F.; Mittler, D.; Hirsch, T.; Gerhards, A.; Lehnhardt, M.; Voss, B.; Steinau, H.U.; Steinstraesser, L. Transient cutaneous adenoviral gene therapy with human host defense peptide hCAP-18/LL-37 is effective fort the treatment of burn wound infections. Gene Ther. 2005, 12, 1494-1502.
-
(2005)
Gene Ther
, vol.12
, pp. 1494-1502
-
-
Jacobsen, F.1
Mittler, D.2
Hirsch, T.3
Gerhards, A.4
Lehnhardt, M.5
Voss, B.6
Steinau, H.U.7
Steinstraesser, L.8
-
68
-
-
61349169039
-
AMPed up immunity: How antimicrobial peptides have multiple roles in immune defense
-
Lai, Y.; Gallo, R.L. AMPed up immunity: How antimicrobial peptides have multiple roles in immune defense. Trends Immunol. 2009, 30, 131-141.
-
(2009)
Trends Immunol
, vol.30
, pp. 131-141
-
-
Lai, Y.1
Gallo, R.L.2
-
69
-
-
70350442452
-
α-Defensins increase lung fibroblast proliferation and collagen synthesis via β-catenin signaling pathway
-
Han, W.; Wang, W.; Mohammed, K.A.; Su, Y. α-Defensins increase lung fibroblast proliferation and collagen synthesis via β-catenin signaling pathway. FEBS J. 2009, 276, 6603-6614.
-
(2009)
FEBS J
, vol.276
, pp. 6603-6614
-
-
Han, W.1
Wang, W.2
Mohammed, K.A.3
Su, Y.4
-
70
-
-
58149526865
-
Antimicrobial human beta-defensin-2 stimulates migration, proliferation and tube formation of human umbilical vein endothelial cells
-
Baroni, A.; Donnarumma, G.; Paoletti, I.; Longanesi-Cattani, I.; Bifulco, K.; Tufano, M.A.; Carriero, M.V. Antimicrobial human beta-defensin-2 stimulates migration, proliferation and tube formation of human umbilical vein endothelial cells. Peptides 2009, 30, 267-272.
-
(2009)
Peptides
, vol.30
, pp. 267-272
-
-
Baroni, A.1
Donnarumma, G.2
Paoletti, I.3
Longanesi-Cattani, I.4
Bifulco, K.5
Tufano, M.A.6
Carriero, M.V.7
-
71
-
-
54149094445
-
Nuclear lokalization of hBD-1 in human keratinocytes
-
Bick, R.J.; Poindexter, B.J.; Buja, L.M.; Lawyer, C.H.; Milner, S.M.; Bhat, S. Nuclear lokalization of hBD-1 in human keratinocytes. J. Burn Wounds 2007, 7, 25-32.
-
(2007)
J. Burn Wounds
, vol.7
, pp. 25-32
-
-
Bick, R.J.1
Poindexter, B.J.2
Buja, L.M.3
Lawyer, C.H.4
Milner, S.M.5
Bhat, S.6
-
72
-
-
77953812194
-
Human β-defensin 1 A restless warrior against allergies, infections and cancer
-
Prado-Montes de Orca, E. Human β-defensin 1: A restless warrior against allergies, infections and cancer. Int. J. Biochem. Cell Biol. 2010, 42, 800-804.
-
(2010)
Int. J. Biochem. Cell Biol.
, vol.42
, pp. 800-804
-
-
Prado-Montes de Orca, E.1
-
73
-
-
3843142873
-
Interleukin 6 and interleukin 8 as potential biomarkers for oral cavity and oropharyngeal squamous cell carcinoma
-
St John, M.A.; Li, Y.; Zhou, X.; Denny, P.; Ho, C.M.; Montemagno, C.; Shi, W.; Qi, F.; Wu, B.; Sinha, U.; Jordan, R.; Wolinsky, L.; Park, N.H.; Liu, H.; Abemayor, E.; Wong, D.T. Interleukin 6 and interleukin 8 as potential biomarkers for oral cavity and oropharyngeal squamous cell carcinoma. Arch. Otolaryngol. Head Neck Surg. 2004, 130, 929-935.
-
(2004)
Arch. Otolaryngol. Head Neck Surg.
, vol.130
, pp. 929-935
-
-
St John, M.A.1
Li, Y.2
Zhou, X.3
Denny, P.4
Ho, C.M.5
Montemagno, C.6
Shi, W.7
Qi, F.8
Wu, B.9
Sinha, U.10
Jordan, R.11
Wolinsky, L.12
Park, N.H.13
Liu, H.14
Abemayor, E.15
Wong, D.T.16
-
74
-
-
67651250530
-
Carcinoma cell-derived chemokines and their presence in oral fluid
-
Michiels, K.; Schutyser, E.; Conings, R.; Lenaerts, J.P.; Put, W.; Nuyts, S.; Delaere, P.; Jacobs, R.; Struyf, S.; Proost, P.; van Damme, J. Carcinoma cell-derived chemokines and their presence in oral fluid. Eur. J. Oral Sci. 2009, 117, 362-368.
-
(2009)
Eur. J. Oral Sci.
, vol.117
, pp. 362-368
-
-
Michiels, K.1
Schutyser, E.2
Conings, R.3
Lenaerts, J.P.4
Put, W.5
Nuyts, S.6
Delaere, P.7
Jacobs, R.8
Struyf, S.9
Proost, P.10
van Damme, J.11
-
75
-
-
70350437749
-
Molecular markers in oral epithelial dysplasia: Review
-
Pitiyage, G.; Tilakaratne, W.M.; Tavassoli, M.; Warnakulasuriya, S. Molecular markers in oral epithelial dysplasia: Review. J. Oral Pathol. Med. 2009, 38, 737-752.
-
(2009)
J. Oral Pathol. Med.
, vol.38
, pp. 737-752
-
-
Pitiyage, G.1
Tilakaratne, W.M.2
Tavassoli, M.3
Warnakulasuriya, S.4
-
76
-
-
68349121579
-
Cellular and molecular pathways linking inflammation and cancer
-
Porta, C.; Larghi, P.; Rimoldi, M.; Totaro, M.G.; Allavena, P. Mantovani, A.; Sica, A. Cellular and molecular pathways linking inflammation and cancer. Immunobiology 2009, 214, 761-777.
-
(2009)
Immunobiology
, vol.214
, pp. 761-777
-
-
Porta, C.1
Larghi, P.2
Rimoldi, M.3
Totaro, M.G.4
Allavena, P.5
Mantovani, A.6
Sica, A.7
-
77
-
-
47749155653
-
Cancer related inflammation: The macrophage connection
-
Sica, A.; Allavena, P.; Mantovani, A. Cancer related inflammation: The macrophage connection. Cancer Lett. 2008, 267, 204-215.
-
(2008)
Cancer Lett
, vol.267
, pp. 204-215
-
-
Sica, A.1
Allavena, P.2
Mantovani, A.3
-
78
-
-
34249096131
-
Chronic periodontitis and the risk of tongue cancer
-
Tezal, M.; Sullivan, M.A.; Reid, M.E.; Marshall, J.R.; Hyland, A.; Loree, T.; Lillis, C.; Hauck, L.; Wactawski-Wende, J.; Scannapieco, F.A. Chronic periodontitis and the risk of tongue cancer. Arch. Otolaryngol. Head Neck Surg. 2007, 133, 450-454.
-
(2007)
Arch. Otolaryngol. Head Neck Surg.
, vol.133
, pp. 450-454
-
-
Tezal, M.1
Sullivan, M.A.2
Reid, M.E.3
Marshall, J.R.4
Hyland, A.5
Loree, T.6
Lillis, C.7
Hauck, L.8
Wactawski-Wende, J.9
Scannapieco, F.A.10
-
79
-
-
70349317367
-
Chronic periodontitis and the incidence of head and neck squamous cell carcinoma
-
Tezal, M.; Sullivan, M.A.; Hyland, A.; Marshall, J.R.; Stoler, D.; Reid, M.E.; Loree, T.R.; Rigual, N.R.; Merzianu, M.; Hauck, L.; Lillis, C.; Wactawski-Wende, J.; Scannapieco, F.A. Chronic periodontitis and the incidence of head and neck squamous cell carcinoma. Cancer Epidemiol. Biomarkers Prev. 2009, 18, 2406-2412.
-
(2009)
Cancer Epidemiol. Biomarkers Prev.
, vol.18
, pp. 2406-2412
-
-
Tezal, M.1
Sullivan, M.A.2
Hyland, A.3
Marshall, J.R.4
Stoler, D.5
Reid, M.E.6
Loree, T.R.7
Rigual, N.R.8
Merzianu, M.9
Hauck, L.10
Lillis, C.11
Wactawski-Wende, J.12
Scannapieco, F.A.13
-
80
-
-
0037391009
-
Cancer-specific loss of beta-defensin 1 in renal and prostatic carcinomas
-
Donald, C.D.; Sun, C.Q.; Lim, S.D.; Macoska, J.; Cohen, C.; Amin, M.B.; Young, A.N.; Ganz, T.A.; Marshall, F.F.; Petros, J.A. Cancer-specific loss of beta-defensin 1 in renal and prostatic carcinomas. Lab. Invest. 2003, 83, 501-505.
-
(2003)
Lab. Invest.
, vol.83
, pp. 501-505
-
-
Donald, C.D.1
Sun, C.Q.2
Lim, S.D.3
Macoska, J.4
Cohen, C.5
Amin, M.B.6
Young, A.N.7
Ganz, T.A.8
Marshall, F.F.9
Petros, J.A.10
-
81
-
-
33749036894
-
Human beta-defensin-1, a potential chromosome 8p tumor suppressor: Control of transcription and induction of apoptosis in renal cell carcinoma
-
Sun, C.Q.; Arnold, R.; Fernandez-Golarz, C.; Parrish, A.B.; Almekinder, T.; He, J.; Ho, S.M.; Svoboda, P.; Pohl, J.; Marshall, F.F.; Petros, J.A. Human beta-defensin-1, a potential chromosome 8p tumor suppressor: Control of transcription and induction of apoptosis in renal cell carcinoma. Cancer Res. 2006, 66, 8542-8549.
-
(2006)
Cancer Res
, vol.66
, pp. 8542-8549
-
-
Sun, C.Q.1
Arnold, R.2
Fernandez-Golarz, C.3
Parrish, A.B.4
Almekinder, T.5
He, J.6
Ho, S.M.7
Svoboda, P.8
Pohl, J.9
Marshall, F.F.10
Petros, J.A.11
-
82
-
-
68949197492
-
Loss of human beta-defensin 1 2 and 3 expression in oral squamous cell carcinoma
-
Joly, S.; Compton, L.M.; Pujol, C.; Kurago, Z.B.; Guthmiller, J.M. Loss of human beta-defensin 1, 2, and 3 expression in oral squamous cell carcinoma. Oral Microbiol. Immunol. 2009, 24, 353-360.
-
(2009)
Oral Microbiol. Immunol.
, vol.24
, pp. 353-360
-
-
Joly, S.1
Compton, L.M.2
Pujol, C.3
Kurago, Z.B.4
Guthmiller, J.M.5
-
83
-
-
46149105889
-
Decreased gene expression of human beta-defensin-1 in the development of squamous cell carcinoma of the oral cavity
-
Wenghoefer, M.; Pantelis, A.; Dommisch, H.; Reich, R.;, Martini, M.; Allam, J.P.; Novak, N.; Bergé, S.; Jepsen, S.; Winter, J. Decreased gene expression of human beta-defensin-1 in the development of squamous cell carcinoma of the oral cavity. Int. J. Oral Maxillofac. Surg. 2008, 37, 660-663.
-
(2008)
Int. J. Oral Maxillofac. Surg.
, vol.37
, pp. 660-663
-
-
Wenghoefer, M.1
Pantelis, A.2
Dommisch, H.3
Reich, R.4
Martini, M.5
Allam, J.P.6
Novak, N.7
Bergé, S.8
Jepsen, S.9
Winter, J.10
-
84
-
-
67449091655
-
Expression profile of human beta-defensin 3 in oral squamous cell carcinoma
-
Kesting, M.R.; Loeffelbein, D.J.; Hasler, R.J.; Wolff, K.D.; Rittig, A.; Schulte, M.; Hirsch, T.; Wagenpfeil, S.; Jacobsen, F.; Steinstraesser, L. Expression profile of human beta-defensin 3 in oral squamous cell carcinoma. Cancer Invest. 2009, 27, 575-581.
-
(2009)
Cancer Invest
, vol.27
, pp. 575-581
-
-
Kesting, M.R.1
Loeffelbein, D.J.2
Hasler, R.J.3
Wolff, K.D.4
Rittig, A.5
Schulte, M.6
Hirsch, T.7
Wagenpfeil, S.8
Jacobsen, F.9
Steinstraesser, L.10
-
85
-
-
78049378642
-
Gene expression of oncogenes, antimicrobial peptides, and cytokines in the development of oral leukoplakia
-
Wenghoefer, M.; Pantelis, A.; Najafi, T.; Deschner, J.; Allam, J.P.; Novak, N.; Reich, R.; Martini, M.; Bergé, S.; Fischer, HP.; Jepsen, S.; Winter, J. Gene expression of oncogenes, antimicrobial peptides, and cytokines in the development of oral leukoplakia. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 2010, 110, 351-356.
-
(2010)
Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod.
, vol.110
, pp. 351-356
-
-
Wenghoefer, M.1
Pantelis, A.2
Najafi, T.3
Deschner, J.4
Allam, J.P.5
Novak, N.6
Reich, R.7
Martini, M.8
Bergé, S.9
Fischer, H.P.10
Jepsen, S.11
Winter, J.12
-
86
-
-
79551598557
-
High α-defensin and S100A7 expression and missing DOC-1 down-regulation characterize irritation fibromas of the oral cavity and may counteract malignant transformation
-
Winter, J.; Pantelis, A.; Allam, J.P.; Novak, N.; Reich, R.; Martini, M.; Bergé, S.; Deschner, J.; Jepsen, S.; Wenghoefer, M. High α-defensin and S100A7 expression and missing DOC-1 down-regulation characterize irritation fibromas of the oral cavity and may counteract malignant transformation. J. Craniofac. Surg. 2011, 22, 100-104.
-
(2011)
J. Craniofac. Surg.
, vol.22
, pp. 100-104
-
-
Winter, J.1
Pantelis, A.2
Allam, J.P.3
Novak, N.4
Reich, R.5
Martini, M.6
Bergé, S.7
Deschner, J.8
Jepsen, S.9
Wenghoefer, M.10
-
87
-
-
75049083399
-
A 3' UTR transition within DEFB1 is associated with chronic and aggressive periodontitis
-
Schaefer, A.S.; Richter, G.M.; Nothnagel, M.; Laine, M.L.; Rühling, A.; Schäfer, C.; Cordes, N.; Noack, B.; Folwaczny, M.; Glas, J.; Dörfer, C.; Dommisch, H.; Groessner-Schreiber, B.; Jepsen, S.; Loos, B.G.; Schreiber, S. A 3' UTR transition within DEFB1 is associated with chronic and aggressive periodontitis. Genes Immun. 2010, 11, 45-54.
-
(2010)
Genes Immun
, vol.11
, pp. 45-54
-
-
Schaefer, A.S.1
Richter, G.M.2
Nothnagel, M.3
Laine, M.L.4
Rühling, A.5
Schäfer, C.6
Cordes, N.7
Noack, B.8
Folwaczny, M.9
Glas, J.10
Dörfer, C.11
Dommisch, H.12
Groessner-Schreiber, B.13
Jepsen, S.14
Loos, B.G.15
Schreiber, S.16
-
88
-
-
0022886732
-
In vitro tumor cell cytolysis mediated by peptide defensins of human and rabbit granulocytes
-
Lichtenstein, A.; Ganz, T.; Selsted, M.E.; Lehrer, R.I. In vitro tumor cell cytolysis mediated by peptide defensins of human and rabbit granulocytes. Blood 1986, 68, 1407-1410.
-
(1986)
Blood
, vol.68
, pp. 1407-1410
-
-
Lichtenstein, A.1
Ganz, T.2
Selsted, M.E.3
Lehrer, R.I.4
-
89
-
-
69949180750
-
Attraction and activation of dendritic cells at the site of tumor elicits potent antitumor immunity
-
Lapteva, N.; Aldrich, M.; Rollins, L.; Ren, W.; Goltsova, T.; Chen, S.Y.; Huang, X.F. Attraction and activation of dendritic cells at the site of tumor elicits potent antitumor immunity. Mol. Ther. 2009, 17, 1626-1636.
-
(2009)
Mol. Ther.
, vol.17
, pp. 1626-1636
-
-
Lapteva, N.1
Aldrich, M.2
Rollins, L.3
Ren, W.4
Goltsova, T.5
Chen, S.Y.6
Huang, X.F.7
-
90
-
-
30544432722
-
Identification of HNP3 as a tumor marker in CD4+ and CD4- lymphocytes of patients with cutaneous cell lymphoma
-
Escher, N.; Spies-Weisshart, B.; Kaatz, M.; Melle, C.; Bleul, A.; Driesch, D.; Wollina, U.; von Eggeling, F. Identification of HNP3 as a tumor marker in CD4+ and CD4- lymphocytes of patients with cutaneous cell lymphoma. Eur. J. Cancer 2006, 42, 249-255.
-
(2006)
Eur. J. Cancer
, vol.42
, pp. 249-255
-
-
Escher, N.1
Spies-Weisshart, B.2
Kaatz, M.3
Melle, C.4
Bleul, A.5
Driesch, D.6
Wollina, U.7
von Eggeling, F.8
-
91
-
-
77958507848
-
Defensins alpha 6 (DEFA 6) overexpression threshold of over 60 fold can distinguish between adenoma and fully blown colon carcinoma in individual patients
-
doi:10.1186/1471-2407-10-588
-
Radeva, M.Y.; Jahns, F.; Wilhelm, A.; Glei, M.; Settmacher, U.; Greulich, K.O.; Mothes, H. Defensins alpha 6 (DEFA 6) overexpression threshold of over 60 fold can distinguish between adenoma and fully blown colon carcinoma in individual patients. BMC Cancer 2010, 10, doi:10.1186/1471-2407-10-588.
-
(2010)
BMC Cancer
, vol.10
-
-
Radeva, M.Y.1
Jahns, F.2
Wilhelm, A.3
Glei, M.4
Settmacher, U.5
Greulich, K.O.6
Mothes, H.7
-
92
-
-
21444442023
-
Antimicrobial peptide therapeutics for cystic fibrosis
-
Zhang, L.; Parente, J.; Harris, S.M.; Woods, D.E.; Hancock, R.E.W.; Falla, T.J. Antimicrobial peptide therapeutics for cystic fibrosis. Antimicrob. Agents Chemother 2005, 49, 2921-2927.
-
(2005)
Antimicrob. Agents Chemother
, vol.49
, pp. 2921-2927
-
-
Zhang, L.1
Parente, J.2
Harris, S.M.3
Woods, D.E.4
Hancock, R.E.W.5
Falla, T.J.6
-
93
-
-
0032567666
-
Expression of antimicrobial peptides has an antitumour effect in human cells
-
Winder, D.; Gunzburg, W.H.; Erfle, V.; Salmons, B. Expression of antimicrobial peptides has an antitumour effect in human cells. Biochem. Biophys. Res. Commun. 1998, 242, 608-612.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.242
, pp. 608-612
-
-
Winder, D.1
Gunzburg, W.H.2
Erfle, V.3
Salmons, B.4
-
94
-
-
0037742621
-
A novel lytic peptide composed of D L amino acids selectively kills cancer cells in culture and in mice
-
Papo, N.; Shahar, M.; Eisenbach, L.; Shai, Y. A novel lytic peptide composed of D, L amino acids selectively kills cancer cells in culture and in mice. J. Biol. Chem. 2003, 278, 21018-21023.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 21018-21023
-
-
Papo, N.1
Shahar, M.2
Eisenbach, L.3
Shai, Y.4
-
95
-
-
0035866780
-
RGD-tachyplesin inhibits tumor growth
-
Chen, Y.; Xu, X.; Hong, S.; Chen, J.; Liub, N.; Underhill, C.B.; Creswell, K.; Zhang, L. RGD-tachyplesin inhibits tumor growth. Cancer Res. 2001, 61, 2434-2438.
-
(2001)
Cancer Res
, vol.61
, pp. 2434-2438
-
-
Chen, Y.1
Xu, X.2
Hong, S.3
Chen, J.4
Liub, N.5
Underhill, C.B.6
Creswell, K.7
Zhang, L.8
-
96
-
-
18544366816
-
Host defense peptides as new weapons in cancer treatment
-
Papo, N.; Shai, Y. Host defense peptides as new weapons in cancer treatment. Cell. Mol. Life Sci. 2005, 62, 784-790.
-
(2005)
Cell. Mol. Life Sci.
, vol.62
, pp. 784-790
-
-
Papo, N.1
Shai, Y.2
-
97
-
-
33746532309
-
Peptide antimicrobial agents
-
Jenssen, H.; Hamill, P.; Hancock, R.E.W. Peptide antimicrobial agents. Clin. Microbiol. Rev. 2006, 19, 491-511.
-
(2006)
Clin. Microbiol. Rev.
, vol.19
, pp. 491-511
-
-
Jenssen, H.1
Hamill, P.2
Hancock, R.E.W.3
-
98
-
-
33845699790
-
Antimicrobial and host defense peptides as new anti-infective therapeutic strategies
-
Hancock, R.E.W.; Sahl, H.G. Antimicrobial and host defense peptides as new anti-infective therapeutic strategies. Nat. Biotechnol. 2006, 24, 1551-1557.
-
(2006)
Nat. Biotechnol.
, vol.24
, pp. 1551-1557
-
-
Hancock, R.E.W.1
Sahl, H.G.2
-
99
-
-
67649295450
-
Antimicobial peptide mimics for improved therapeutic properties
-
Rotem, S.; Mor, A. Antimicobial peptide mimics for improved therapeutic properties. Biochim. Biophys. Acta 2009, 1788, 1582-1592.
-
(2009)
Biochim. Biophys. Acta
, vol.1788
, pp. 1582-1592
-
-
Rotem, S.1
Mor, A.2
-
100
-
-
77957329669
-
Cationic amphiphiles, a new generation of antimicrobials inspired by the natural antimicrobial peptide scaffold
-
Findlay, B.; Zhanel, G.G.; Schweizer, F. Cationic amphiphiles, a new generation of antimicrobials inspired by the natural antimicrobial peptide scaffold. Antimicrob. Agents Chemother 2010, 54, 4049-4058.
-
(2010)
Antimicrob. Agents Chemother
, vol.54
, pp. 4049-4058
-
-
Findlay, B.1
Zhanel, G.G.2
Schweizer, F.3
-
101
-
-
79960936612
-
Multifunctional cationic host defense peptides and their clinical applications
-
Yeung, A.T.Y.; Gellatly, S.L.; Hancock, R.E.W. Multifunctional cationic host defense peptides and their clinical applications. Cell. Mol. Life Sci. 2011, 68, 2161-2176.
-
(2011)
Cell. Mol. Life Sci.
, vol.68
, pp. 2161-2176
-
-
Yeung, A.T.Y.1
Gellatly, S.L.2
Hancock, R.E.W.3
|