-
1
-
-
0016164836
-
A model for the chemotherapy of acute leukemia with 1-beta-D- arabinofuranosylcytosine
-
Momparler RL. A model for the chemotherapy of acute leukemia with 1-beta-D- arabinofuranosylcytosine. Cancer Res 1974; 34(8): 1775-1787.
-
(1974)
Cancer Res
, vol.34
, Issue.8
, pp. 1775-1787
-
-
Momparler, R.L.1
-
2
-
-
0020082901
-
A pilot study of high-dose 1-beta-D-arabinofuranosylcytosine for acute leukemia and refractory lymphoma: Clinical response and pharmacology
-
Early AP, Preisler HD, Slocum H, Rustum YM. A pilot study of high-dose 1-beta-D-arabinofuranosylcytosine for acute leukemia and refractory lymphoma: clinical response and pharmacology. Cancer Res 1982; 42(4): 1587-94.
-
(1982)
Cancer Res
, vol.42
, Issue.4
, pp. 1587-1594
-
-
Early, A.P.1
Preisler, H.D.2
Slocum, H.3
Rustum, Y.M.4
-
3
-
-
20344381786
-
Cytotoxic effects of novel amphiphilic dimers consisting of 5-fluorodeoxyuridine and arabinofuranosylcytosine in cross-resistant H9 human lymphoma cells
-
Saiko P, Horvath Z, Illmer C, Madlener S, et al. Cytotoxic effects of novel amphiphilic dimers consisting of 5-fluorodeoxyuridine and arabinofuranosylcytosine in cross-resistant H9 human lymphoma cells. Leuk Res 2005; 29(7): 785-791.
-
(2005)
Leuk Res
, vol.29
, Issue.7
, pp. 785-791
-
-
Saiko, P.1
Horvath, Z.2
Illmer, C.3
Madlener, S.4
-
4
-
-
0033050165
-
Multicenter phase II study of capecitabine in paclitaxel-refractory metastatic breast cancer
-
Blum JL, Jones SE, Buzdar AU, et al. Multicenter phase II study of capecitabine in paclitaxel-refractory metastatic breast cancer. J Clin Oncol 1999; 17(2): 485-493.
-
(1999)
J Clin Oncol
, vol.17
, Issue.2
, pp. 485-493
-
-
Blum, J.L.1
Jones, S.E.2
Buzdar, A.U.3
-
5
-
-
18444417397
-
Randomised, phase II trial comparing oral capecitabine (Xeloda) with paclitaxel in patients with metastatic/advanced breast cancer pretreated with anthracyclines
-
Talbot DC, Moiseyenko V, Van Belle S, et al. Randomised, phase II trial comparing oral capecitabine (Xeloda) with paclitaxel in patients with metastatic/advanced breast cancer pretreated with anthracyclines. Br J Cancer 2002; 86(9): 1367-1372.
-
(2002)
Br J Cancer
, vol.86
, Issue.9
, pp. 1367-1372
-
-
Talbot, D.C.1
Moiseyenko, V.2
Van Belle, S.3
-
6
-
-
0034778024
-
Randomized, open-label, phase II trial of oral capecitabine (Xeloda) vs. a reference arm of intravenous CMF (cyclophosphamide, methotrexate and 5-fluorouracil) as first-line therapy for advanced/metastatic breast cancer
-
Oshaughnessy JA, Blum J, Moiseyenko V, et al. Randomized, open-label, phase II trial of oral capecitabine (Xeloda) vs. a reference arm of intravenous CMF (cyclophosphamide, methotrexate and 5-fluorouracil) as first-line therapy for advanced/metastatic breast cancer. Ann Oncol 2001; 12(9): 1247-1254.
-
(2001)
Ann Oncol
, vol.12
, Issue.9
, pp. 1247-1254
-
-
Oshaughnessy, J.A.1
Blum, J.2
Moiseyenko, V.3
-
7
-
-
16244398779
-
In vitro and in vivo antitumor activity of novel amphiphilic dimers consisting of 5 -fluorodeoxyuridine and arabinofuranosylcytosine
-
Saiko P, Horvath Z, Bauer W, et al. In vitro and in vivo antitumor activity of novel amphiphilic dimers consisting of 5 -fluorodeoxyuridine and arabinofuranosylcytosine. Int J Oncol 2004; 25(2): 357-364.
-
(2004)
Int J Oncol
, vol.25
, Issue.2
, pp. 357-364
-
-
Saiko, P.1
Horvath, Z.2
Bauer, W.3
-
8
-
-
0035184489
-
Reduced cellular transport and activation of fluoropyrimidine nucleosides and resistance in human lymphocytic cell lines selected for arabinosylcytosine resistance
-
Agarwal RP, Han T, Fernandez M. Reduced cellular transport and activation of fluoropyrimidine nucleosides and resistance in human lymphocytic cell lines selected for arabinosylcytosine resistance. Biochem Pharmacol 2001; 61(1): 39-47.
-
(2001)
Biochem Pharmacol
, vol.61
, Issue.1
, pp. 39-47
-
-
Agarwal, R.P.1
Han, T.2
Fernandez, M.3
-
9
-
-
0021719254
-
Isolation and characterization of a deoxycytidine kinase-deficient human promyelocytic leukemic cell line highly resistant to 1-beta-D- arabinofuranosylcytosine
-
Bhalla K, Nayak R, Grant S. Isolation and characterization of a deoxycytidine kinase-deficient human promyelocytic leukemic cell line highly resistant to 1-beta-D- arabinofuranosylcytosine. Cancer Res 1984; 44(11): 5029-5037.
-
(1984)
Cancer Res
, vol.44
, Issue.11
, pp. 5029-5037
-
-
Bhalla, K.1
Nayak, R.2
Grant, S.3
-
10
-
-
0017369396
-
Metabolism of 5-fluorouracil in sensitive and resistant Novikoff hepatoma cells
-
Wilkinson DS, Crumley J. Metabolism of 5-fluorouracil in sensitive and resistant Novikoff hepatoma cells. J Biol Chem 1977; 252(3): 1051-1056.
-
(1977)
J Biol Chem
, vol.252
, Issue.3
, pp. 1051-1056
-
-
Wilkinson, D.S.1
Crumley, J.2
-
11
-
-
0033844236
-
The novel heterodinucleoside dimer 5-FdU-NOAC is a potent cytotoxic drug and a p53-independent inducer of apoptosis in the androgen-independent human prostate cancer cell lines PC-3 and DU-145
-
Cattaneo-Pangrazzi RM, Schott H, Schwendener RA. The novel heterodinucleoside dimer 5-FdU-NOAC is a potent cytotoxic drug and a p53-independent inducer of apoptosis in the androgen-independent human prostate cancer cell lines PC-3 and DU-145. Prostate 2000; 45(1): 8-18.
-
(2000)
Prostate
, vol.45
, Issue.1
, pp. 8-18
-
-
Cattaneo-Pangrazzi, R.M.1
Schott, H.2
Schwendener, R.A.3
-
12
-
-
0021870861
-
Overproduction of p53 antigen makes established cells highly tumorigenic
-
Eliyahu D, Michalovitz D, Oren M. Overproduction of p53 antigen makes established cells highly tumorigenic. Nature 1985; 316(6024): 158-160.
-
(1985)
Nature
, vol.316
, Issue.6024
, pp. 158-160
-
-
Eliyahu, D.1
Michalovitz, D.2
Oren, M.3
-
13
-
-
0025111068
-
Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53
-
Michalovitz D, Halevy O, Oren M. Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53. Cell 1990; 62(4): 671-680.
-
(1990)
Cell
, vol.62
, Issue.4
, pp. 671-680
-
-
Michalovitz, D.1
Halevy, O.2
Oren, M.3
-
14
-
-
0021272340
-
Current NCI preclinical antitumor screening in vivo: Results of tumor panel screening, 1976-1982, and future directions
-
Venditti JM, Wesley RA, Plowman J. Current NCI preclinical antitumor screening in vivo: results of tumor panel screening, 1976-1982, and future directions. Adv Pharmacol Chemother 1984; 20: 1-20.
-
(1984)
Adv Pharmacol Chemother
, vol.20
, pp. 1-20
-
-
Venditti, J.M.1
Wesley, R.A.2
Plowman, J.3
-
15
-
-
0031035181
-
An information-intensive approach to the molecular pharmacology of cancer
-
Weinstein JN, Myers TG, O'Connor PM, et al. An information-intensive approach to the molecular pharmacology of cancer. Science 1997; 275(5298): 343-349.
-
(1997)
Science
, vol.275
, Issue.5298
, pp. 343-349
-
-
Weinstein, J.N.1
Myers, T.G.2
O'Connor, P.M.3
-
16
-
-
0029119742
-
Effects of cell cycle, wild-type p53 and DNA damage on p21CIP1/Waf1 expression in human breast epithelial cells
-
Gudas J, Nguyen H, Li T, Hill D, Cowan KH. Effects of cell cycle, wild-type p53 and DNA damage on p21CIP1/Waf1 expression in human breast epithelial cells. Oncogene 1995; 11(2): 253-261.
-
(1995)
Oncogene
, vol.11
, Issue.2
, pp. 253-261
-
-
Gudas, J.1
Nguyen, H.2
Li, T.3
Hill, D.4
Cowan, K.H.5
-
17
-
-
0031890636
-
Role of MDM2 overexpression in doxorubicin resistance of breast carcinoma
-
Suzuki A, Toi M, Yamamoto Y, Saji S, Muta M, Tominaga T. Role of MDM2 overexpression in doxorubicin resistance of breast carcinoma. Jpn J Cancer Res 1998; 89(2): 221-227.
-
(1998)
Jpn J Cancer Res
, vol.89
, Issue.2
, pp. 221-227
-
-
Suzuki, A.1
Toi, M.2
Yamamoto, Y.3
Saji, S.4
Muta, M.5
Tominaga, T.6
-
18
-
-
0032580310
-
Regulation of BRCA1 and BRCA2 expression in human breast cancer cells by DNA-damaging agents
-
Andres JL, Fan S, Turkel GJ, et al. Regulation of BRCA1 and BRCA2 expression in human breast cancer cells by DNA-damaging agents. Oncogene 1998; 16(17): 2229-2241.
-
(1998)
Oncogene
, vol.16
, Issue.17
, pp. 2229-2241
-
-
Andres, J.L.1
Fan, S.2
Turkel, G.J.3
-
19
-
-
0033368192
-
De novo deletions of p53 gene and wild-type p53 correlate with acquired cisplatin-resistance in human osteosarcoma OST cell line
-
Asada N, Tsuchiya H, Tomita K. De novo deletions of p53 gene and wild-type p53 correlate with acquired cisplatin-resistance in human osteosarcoma OST cell line. Anticancer Res 1999; 19(6B): 5131-5137.
-
(1999)
Anticancer Res
, vol.19
, Issue.6 B
, pp. 5131-5137
-
-
Asada, N.1
Tsuchiya, H.2
Tomita, K.3
-
20
-
-
0037181478
-
Caspase-3 is not essential for DNA fragmentation in MCF-7 cells during apoptosis induced by the pyrrolo-1,5-benzoxazepme, PBOX-6
-
Mc Gee MM, Hyland E, Campiani G, Ramunno A, Nacci V, Zisterer DM. Caspase-3 is not essential for DNA fragmentation in MCF-7 cells during apoptosis induced by the pyrrolo-1,5-benzoxazepme, PBOX-6. FEBS Lett 2002; 515(1-3): 66-70.
-
(2002)
FEBS Lett
, vol.515
, Issue.1-3
, pp. 66-70
-
-
Mc Gee, M.M.1
Hyland, E.2
Campiani, G.3
Ramunno, A.4
Nacci, V.5
Zisterer, D.M.6
-
21
-
-
0035839144
-
Caspase activation in response to cytotoxic Rana catesbeiana ribonuclease in MCF-7 cells
-
Hu CC, Tang CH, Wang JJ. Caspase activation in response to cytotoxic Rana catesbeiana ribonuclease in MCF-7 cells. FEBS Lett 2001; 503(1): 65-68.
-
(2001)
FEBS Lett
, vol.503
, Issue.1
, pp. 65-68
-
-
Hu, C.C.1
Tang, C.H.2
Wang, J.J.3
-
22
-
-
0034692451
-
Uncertain identity of doxorubicin-resistant MCF-7 cell lines expressing mutated p53
-
Pirnia F, Breuleux M, Schneider E, et al. Uncertain identity of doxorubicin-resistant MCF-7 cell lines expressing mutated p53. J Natl Cancer Inst 2000; 92(18): 1535-1536.
-
(2000)
J Natl Cancer Inst
, vol.92
, Issue.18
, pp. 1535-1536
-
-
Pirnia, F.1
Breuleux, M.2
Schneider, E.3
-
23
-
-
0035798476
-
Differential effect of vinorelbine versus paclitaxel on ERK2 kinase activity during apoptosis in MCF-7 cells
-
Liu XM, Wang LG, Kreis W, Budman DR, Adams LM. Differential effect of vinorelbine versus paclitaxel on ERK2 kinase activity during apoptosis in MCF-7 cells. Br J Cancer 2001; 85(9): 1403-1411.
-
(2001)
Br J Cancer
, vol.85
, Issue.9
, pp. 1403-1411
-
-
Liu, X.M.1
Wang, L.G.2
Kreis, W.3
Budman, D.R.4
Adams, L.M.5
-
24
-
-
0033214624
-
Cleavage of automodified poly(ADP-ribose) polymerase during apoptosis. Evidence for involvement of caspase-7
-
Germain M, Affar EB, D'Amours D, Dixit VM, Salvesen GS, Poirier GG. Cleavage of automodified poly(ADP-ribose) polymerase during apoptosis. Evidence for involvement of caspase-7. J Biol Chem 1999; 274(40): 28379-28384.
-
(1999)
J Biol Chem
, vol.274
, Issue.40
, pp. 28379-28384
-
-
Germain, M.1
Affar, E.B.2
D'Amours, D.3
Dixit, V.M.4
Salvesen, G.S.5
Poirier, G.G.6
-
25
-
-
0032546795
-
Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis
-
Janicke RU, Ng P, Sprengart ML, Porter AG. Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis. J Biol Chem 1998; 273(25): 15540-15545.
-
(1998)
J Biol Chem
, vol.273
, Issue.25
, pp. 15540-15545
-
-
Janicke, R.U.1
Ng, P.2
Sprengart, M.L.3
Porter, A.G.4
-
26
-
-
0034117177
-
Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis
-
Daugas E, Susin SA, Zamzami N, et al. Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis. Faseb J 2000; 14(5): 729-739.
-
(2000)
Faseb J
, vol.14
, Issue.5
, pp. 729-739
-
-
Daugas, E.1
Susin, S.A.2
Zamzami, N.3
-
27
-
-
0027487005
-
Synergistic action of tiazofurin with hypoxanthine and allopurinol in human neuroectodermal tumor cell lines
-
Szekeres T, Schuchter K, Chiba P, et al. Synergistic action of tiazofurin with hypoxanthine and allopurinol in human neuroectodermal tumor cell lines. Biochem Pharmacol 1993; 46(11): 1903-1907.
-
(1993)
Biochem Pharmacol
, vol.46
, Issue.11
, pp. 1903-1907
-
-
Szekeres, T.1
Schuchter, K.2
Chiba, P.3
-
28
-
-
0017620772
-
The mechanism of action of inhibitors of DNA synthesis
-
Cozzarelli NR. The mechanism of action of inhibitors of DNA synthesis. Annu Rev Biochem 1977; 46: 641-668.
-
(1977)
Annu Rev Biochem
, vol.46
, pp. 641-668
-
-
Cozzarelli, N.R.1
-
29
-
-
1242286151
-
Antiproliferative activity and mechanism of action of fatty acid derivatives of arabinofuranosylcytosine in leukemia and solid tumor cell lines
-
Bergman AM, Kuiper CM, Voorn DA, et al. Antiproliferative activity and mechanism of action of fatty acid derivatives of arabinofuranosylcytosine in leukemia and solid tumor cell lines. Biochem Pharmacol 2004; 67(3): 503-511.
-
(2004)
Biochem Pharmacol
, vol.67
, Issue.3
, pp. 503-511
-
-
Bergman, A.M.1
Kuiper, C.M.2
Voorn, D.A.3
-
30
-
-
0020694938
-
Effects of 5-fluoro-2′-deoxyuridine on DNA metabolism in HeLa cells
-
Cheng YC, Nakayama K. Effects of 5-fluoro-2′-deoxyuridine on DNA metabolism in HeLa cells. Mol Pharmacol 1983; 23(1): 171-174.
-
(1983)
Mol Pharmacol
, vol.23
, Issue.1
, pp. 171-174
-
-
Cheng, Y.C.1
Nakayama, K.2
-
31
-
-
0014341101
-
Inhibition of mammalian DNA polymerase by the 5′-triphosphate of 1-beta-d-arabinofuranosylcytosine and the 5′-triphosphate of 9-beta-d-arabinofuranoxyladenine
-
Furth JJ, Cohen SS. Inhibition of mammalian DNA polymerase by the 5′-triphosphate of 1-beta-d-arabinofuranosylcytosine and the 5′-triphosphate of 9-beta-d-arabinofuranoxyladenine. Cancer Res 1968; 28(10): 2061-2067.
-
(1968)
Cancer Res
, vol.28
, Issue.10
, pp. 2061-2067
-
-
Furth, J.J.1
Cohen, S.S.2
-
32
-
-
0019131198
-
Correlation of cytotoxicity with incorporation of ara-C into DNA
-
Kufe DW, Major PP, Egan EM, Beardsley GP. Correlation of cytotoxicity with incorporation of ara-C into DNA. J Biol Chem 1980; 255(19): 8997-9000.
-
(1980)
J Biol Chem
, vol.255
, Issue.19
, pp. 8997-9000
-
-
Kufe, D.W.1
Major, P.P.2
Egan, E.M.3
Beardsley, G.P.4
-
33
-
-
0025611018
-
Metabolism and mechanism of action of 5-fluorouracil
-
Parker WB, Cheng YC. Metabolism and mechanism of action of 5-fluorouracil. Pharmacol Ther 1990; 48(3): 381-395.
-
(1990)
Pharmacol Ther
, vol.48
, Issue.3
, pp. 381-395
-
-
Parker, W.B.1
Cheng, Y.C.2
-
34
-
-
0032006318
-
Comparison of 5-fluoro-2′-deoxyuridine with 5-fluorouracil and their role in the treatment of colorectal cancer
-
van Laar JA, Rustum YM, Ackland SP, van Groeningen CJ, Peters GJ. Comparison of 5-fluoro-2′-deoxyuridine with 5-fluorouracil and their role in the treatment of colorectal cancer. Eur J Cancer 1998; 34(3): 296-306.
-
(1998)
Eur J Cancer
, vol.34
, Issue.3
, pp. 296-306
-
-
Van Laar, J.A.1
Rustum, Y.M.2
Ackland, S.P.3
Van Groeningen, C.J.4
Peters, G.J.5
-
35
-
-
0038392581
-
Non-caspase-mediated apoptosis contributes to the potent cytotoxicity of the enediyne antibiotic lidamycin toward human tumor cells
-
Wang Z, He Q, Liang Y, Wang D, Li Y, Li D. Non-caspase-mediated apoptosis contributes to the potent cytotoxicity of the enediyne antibiotic lidamycin toward human tumor cells. Biochem Pharmacol 2003; 65: 1767-1775.
-
(2003)
Biochem Pharmacol
, vol.65
, pp. 1767-1775
-
-
Wang, Z.1
He, Q.2
Liang, Y.3
Wang, D.4
Li, Y.5
Li, D.6
|