-
1
-
-
0035184489
-
Reduced cellular transport and activation of fluoropyrimidine nucleosides and resistance in human lymphocytic cell lines selected for arabinosylcytosine resistance
-
Agarwal, R.P., Han, T. and Fernandez, M. (2001) Reduced cellular transport and activation of fluoropyrimidine nucleosides and resistance in human lymphocytic cell lines selected for arabinosylcytosine resistance. Biochem Pharmacol 61:39-47.
-
(2001)
Biochem Pharmacol
, vol.61
, pp. 39-47
-
-
Agarwal, R.P.1
Han, T.2
Fernandez, M.3
-
2
-
-
0021719254
-
Isolation and characterization of a deoxycytidine kinase-deficient human promyelocytic leukemic cell line highly resistant to 1-beta-D- arabinofuranosylcytosine
-
Bhalla, K., Nayak, R. and Grant, S. (1984) Isolation and characterization of a deoxycytidine kinase-deficient human promyelocytic leukemic cell line highly resistant to 1-beta-D-arabinofuranosylcytosine. Cancer Res 44:5029-5037.
-
(1984)
Cancer Res
, vol.44
, pp. 5029-5037
-
-
Bhalla, K.1
Nayak, R.2
Grant, S.3
-
3
-
-
0033050165
-
Multicenter phase II study of capecitabine in paclitaxel-refractory metastatic breast cancer
-
Blum, J.L., Jones, S.E., Buzdar, A.U., LoRusso, P.M., Kuter, I., Vogel, C., Osterwalder, B., Burger, H.U., Brown, C.S. and Griffin, T. (1999) Multicenter phase II study of capecitabine in paclitaxel-refractory metastatic breast cancer. J Clin Oncol 17:485-493.
-
(1999)
J Clin Oncol
, vol.17
, pp. 485-493
-
-
Blum, J.L.1
Jones, S.E.2
Buzdar, A.U.3
LoRusso, P.M.4
Kuter, I.5
Vogel, C.6
Osterwalder, B.7
Burger, H.U.8
Brown, C.S.9
Griffin, T.10
-
4
-
-
12244268624
-
Apoptosis-inducing factor (AIF): Key to the conserved caspase-independent pathways of cell death?
-
Cande, C., Cecconi, F., Dessen, P. and Kroemer, G. (2002) Apoptosis-inducing factor (AIF): key to the conserved caspase-independent pathways of cell death? J Cell Sci 115:4727-4734.
-
(2002)
J Cell Sci
, vol.115
, pp. 4727-4734
-
-
Cande, C.1
Cecconi, F.2
Dessen, P.3
Kroemer, G.4
-
5
-
-
0033844236
-
The novel heterodinucleoside dimer 5-FdU-NOAC is a potent cytotoxic drug and a p53-independent inducer of apoptosis in the androgen-independent human prostate cancer cell lines PC-3 and DU-145
-
Cattaneo-Pangrazzi, R.M., Schott, H. and Schwendener, R.A. (2000) The novel heterodinucleoside dimer 5-FdU-NOAC is a potent cytotoxic drug and a p53-independent inducer of apoptosis in the androgen-independent human prostate cancer cell lines PC-3 and DU-145. The Prostate 45:8-18.
-
(2000)
The Prostate
, vol.45
, pp. 8-18
-
-
Cattaneo-Pangrazzi, R.M.1
Schott, H.2
Schwendener, R.A.3
-
6
-
-
0033659280
-
Antineoplastic agents from natural sources: Achievements and future directions
-
Cragg, G.M. and Newman, D.J. (2000) Antineoplastic agents from natural sources: achievements and future directions. Expert Opin Investig Drugs 9:2783-2797.
-
(2000)
Expert Opin Investig Drugs
, vol.9
, pp. 2783-2797
-
-
Cragg, G.M.1
Newman, D.J.2
-
7
-
-
0020082901
-
A pilot study of high-dose 1-beta-D-arabinofuranosylcytosine for acute leukemia and refractory lymphoma: Clinical response and pharmacology
-
Early, A.P., Preisler, H.D., Slocum, H. and Rustum, Y.M. (1982) A pilot study of high-dose 1-beta-D-arabinofuranosylcytosine for acute leukemia and refractory lymphoma: clinical response and pharmacology. Cancer Res 42:1587-1594.
-
(1982)
Cancer Res
, vol.42
, pp. 1587-1594
-
-
Early, A.P.1
Preisler, H.D.2
Slocum, H.3
Rustum, Y.M.4
-
8
-
-
0033214624
-
Cleavage of automodified poly(ADP-ribose) polymerase during apoptosis. Evidence for involvement of caspase-7
-
Germain, M., Affar, E.B., D'Amours, D., Dixit, V.M., Salvesen, G.S. and Poirier, G.G. (1999) Cleavage of automodified poly(ADP-ribose) polymerase during apoptosis. Evidence for involvement of caspase-7. J Biol Chem 274:28379-28384.
-
(1999)
J Biol Chem
, vol.274
, pp. 28379-28384
-
-
Germain, M.1
Affar, E.B.2
D'Amours, D.3
Dixit, V.M.4
Salvesen, G.S.5
Poirier, G.G.6
-
9
-
-
85047695605
-
Maintenance of ATP favours apoptosis over necrosis triggered by benzamide riboside
-
Grusch, M., Polgar, D., Gfatter, S., Leuhuber, K., Huettenbrenner, S., Leisser, C., Fuhrmann, G., Kassie, F., Steinkellner, H., Smid, K., Peters, G.J., Jayaram, H.N., Klepal, W., Szekeres, T., Knasmuller, S. and Krupitza, G. (2002) Maintenance of ATP favours apoptosis over necrosis triggered by benzamide riboside. Cell Death Differ 9:169-178.
-
(2002)
Cell Death Differ
, vol.9
, pp. 169-178
-
-
Grusch, M.1
Polgar, D.2
Gfatter, S.3
Leuhuber, K.4
Huettenbrenner, S.5
Leisser, C.6
Fuhrmann, G.7
Kassie, F.8
Steinkellner, H.9
Smid, K.10
Peters, G.J.11
Jayaram, H.N.12
Klepal, W.13
Szekeres, T.14
Knasmuller, S.15
Krupitza, G.16
-
10
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D. and Weinberg, R.A. (2000) The hallmarks of cancer. Cell 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
11
-
-
0038012547
-
The evolution of cell death programs as prerequisites of multicellularity
-
Huettenbrenner, S., Maier, S., Leisser, C., Polgar, D., Strasser, S., Grusch, M. and Krupitza, G. (2003) The evolution of cell death programs as prerequisites of multicellularity. Mutat Res 543:235-249.
-
(2003)
Mutat Res
, vol.543
, pp. 235-249
-
-
Huettenbrenner, S.1
Maier, S.2
Leisser, C.3
Polgar, D.4
Strasser, S.5
Grusch, M.6
Krupitza, G.7
-
12
-
-
0037016723
-
Lack of correlation between caspase activation and caspase activity assays in paclitaxel-treated MCF-7 breast cancer cells
-
Kottke, T.J., Blajeski, A.L., Meng, X.W., Svingen, P.A., Ruchaud, S., Mesner, P.W. Jr., Boerner, S.A., Samejima, K., Henriquez, N.V., Chilcote, T.J., Lord, J., Salmon, M., Earnshaw, W.C. and Kaufmann, S.H. (2002) Lack of correlation between caspase activation and caspase activity assays in paclitaxel-treated MCF-7 breast cancer cells. J Biol Chem 277:804-815.
-
(2002)
J Biol Chem
, vol.277
, pp. 804-815
-
-
Kottke, T.J.1
Blajeski, A.L.2
Meng, X.W.3
Svingen, P.A.4
Ruchaud, S.5
Mesner Jr., P.W.6
Boerner, S.A.7
Samejima, K.8
Henriquez, N.V.9
Chilcote, T.J.10
Lord, J.11
Salmon, M.12
Earnshaw, W.C.13
Kaufmann, S.H.14
-
13
-
-
33646427699
-
Analysis of mechanisms contributing to AraC-mediated chemoresistance and re-establishment of drug sensitivity by the novel heterodinucleoside phosphate 5-FdUrd-araC
-
Maier, S., Strasser, S., Saiko, P., Leisser, C., Sasgary, S., Grusch, M., Madlener, S., Bader, Y., Hartmann, J., Schott, H., Mader, R.M., Szekeres, T., Fritzer-Szekeres, M. and Krupitza, G. (2006) Analysis of mechanisms contributing to AraC-mediated chemoresistance and re-establishment of drug sensitivity by the novel heterodinucleoside phosphate 5-FdUrd-araC. Apoptosis 11:427-440.
-
(2006)
Apoptosis
, vol.11
, pp. 427-440
-
-
Maier, S.1
Strasser, S.2
Saiko, P.3
Leisser, C.4
Sasgary, S.5
Grusch, M.6
Madlener, S.7
Bader, Y.8
Hartmann, J.9
Schott, H.10
Mader, R.M.11
Szekeres, T.12
Fritzer-Szekeres, M.13
Krupitza, G.14
-
14
-
-
0016164836
-
A model for the chemotherapy of acute leukemia with 1-beta-D- arabinofuranosylcytosine
-
Momparler, R.L. (1974) A model for the chemotherapy of acute leukemia with 1-beta-D-arabinofuranosylcytosine. Cancer Res 34:1775-1787.
-
(1974)
Cancer Res
, vol.34
, pp. 1775-1787
-
-
Momparler, R.L.1
-
15
-
-
0034778024
-
Randomized, open-label, phase II trial of oral capecitabine (Xeloda) vs. a reference arm of intravenous CMF (cyclophosphamide, methotrexate and 5-fluorouracil) as first-line therapy for advanced/metastatic breast cancer
-
Oshaughnessy, J.A., Blum, J., Moiseyenko, V., Jones, S.E., Miles, D., Bell, D., Rosso, R., Mauriac, L., Osterwalder, B., Burger, H.U. and Laws, S. (2001) Randomized, open-label, phase II trial of oral capecitabine (Xeloda) vs. a reference arm of intravenous CMF (cyclophosphamide, methotrexate and 5-fluorouracil) as first-line therapy for advanced/metastatic breast cancer. Ann Oncol 12:1247-1254.
-
(2001)
Ann Oncol
, vol.12
, pp. 1247-1254
-
-
Oshaughnessy, J.A.1
Blum, J.2
Moiseyenko, V.3
Jones, S.E.4
Miles, D.5
Bell, D.6
Rosso, R.7
Mauriac, L.8
Osterwalder, B.9
Burger, H.U.10
Laws, S.11
-
16
-
-
0035868342
-
Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN
-
Pianetti, S., Arsura, M., Romieu-Mourez, R., Coffey, R.J. and Sonenshein, G.E. (2001) Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN. Oncogene 20:1287-1299.
-
(2001)
Oncogene
, vol.20
, pp. 1287-1299
-
-
Pianetti, S.1
Arsura, M.2
Romieu-Mourez, R.3
Coffey, R.J.4
Sonenshein, G.E.5
-
17
-
-
0037112514
-
Protein kinase CK2 promotes aberrant activation of nuclear factor-kappaB, transformed phenotype, and survival of breast cancer cells
-
Romieu-Mourez, R., Landesman-Bollag, E., Seldin, D.C. and Sonenshein, G.E. (2002) Protein kinase CK2 promotes aberrant activation of nuclear factor-kappaB, transformed phenotype, and survival of breast cancer cells. Cancer Res 62:6770-6778.
-
(2002)
Cancer Res
, vol.62
, pp. 6770-6778
-
-
Romieu-Mourez, R.1
Landesman-Bollag, E.2
Seldin, D.C.3
Sonenshein, G.E.4
-
18
-
-
20344381786
-
Cytotoxic effects of novel amphiphilic dimers consisting of 5-fluorodeoxyuridine and arabinofuranosylcytosine in cross-resistant H9 human lymphoma cells
-
Saiko, P., Horvath, Z., Illmer, C., Madlener, S., Bauer, W., Hoechtl, T., Erlach, N., Grusch, M., Krupitza, G., Mader, R.M., Jaeger, W., Schott, H., Agarwal, R.P., Fritzer-Szekeres, M. and Szekeres, T. (2005) Cytotoxic effects of novel amphiphilic dimers consisting of 5-fluorodeoxyuridine and arabinofuranosylcytosine in cross-resistant H9 human lymphoma cells. Leuk Res 29:785-791.
-
(2005)
Leuk Res
, vol.29
, pp. 785-791
-
-
Saiko, P.1
Horvath, Z.2
Illmer, C.3
Madlener, S.4
Bauer, W.5
Hoechtl, T.6
Erlach, N.7
Grusch, M.8
Krupitza, G.9
Mader, R.M.10
Jaeger, W.11
Schott, H.12
Agarwal, R.P.13
Fritzer-Szekeres, M.14
Szekeres, T.15
-
19
-
-
0032490670
-
Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis
-
Stehlik, C., de Martin, R., Kumabashiri, I., Schmid, J.A., Binder, B.R. and Lipp, J. (1998) Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis. J Exp Med 188:211-216.
-
(1998)
J Exp Med
, vol.188
, pp. 211-216
-
-
Stehlik, C.1
De Martin, R.2
Kumabashiri, I.3
Schmid, J.A.4
Binder, B.R.5
Lipp, J.6
-
20
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosis-inducing factor
-
Susin, S.A., Lorenzo, H.K., Zamzami, N., Marzo, I., Snow, B.E., Brothers, G.M., Mangion, J., Jacotot, E., Costantini, P., Loeffler, M., Larochette, N., Goodlett, D.R., Aebersold, R., Siderovski, D.P., Penninger, J.M. and Kroemer, G. (1999) Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 397:441-446.
-
(1999)
Nature
, vol.397
, pp. 441-446
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
Marzo, I.4
Snow, B.E.5
Brothers, G.M.6
Mangion, J.7
Jacotot, E.8
Costantini, P.9
Loeffler, M.10
Larochette, N.11
Goodlett, D.R.12
Aebersold, R.13
Siderovski, D.P.14
Penninger, J.M.15
Kroemer, G.16
-
21
-
-
0027487005
-
Synergistic action of tiazofurin with hypoxanthine and allopurinol in human neuroectodermal tumor cell lines
-
Szekeres, T., Schuchter, K., Chiba, P., Ressmann, G., Lhotka, C., Gharehbaghi, K., Szalay, S.M. and Pillwein, K. (1993) Synergistic action of tiazofurin with hypoxanthine and allopurinol in human neuroectodermal tumor cell lines. Biochem Pharmacol 46:1903-1907.
-
(1993)
Biochem Pharmacol
, vol.46
, pp. 1903-1907
-
-
Szekeres, T.1
Schuchter, K.2
Chiba, P.3
Ressmann, G.4
Lhotka, C.5
Gharehbaghi, K.6
Szalay, S.M.7
Pillwein, K.8
-
22
-
-
18444417397
-
Randomised, phase II trial comparing oral capecitabine (Xeloda) with paclitaxel in patients with metastatic/advanced breast cancer pretreated with anthracyclines
-
Talbot, D.C., Moiseyenko, V., Van Belle, S., O'Reilly, S.M., Alba Conejo, E., Ackland, S., Eisenberg, P., Melnychuk, D., Pienkowski, T., Burger, H.U., Laws, S. and Osterwalder, B. (2002) Randomised, phase II trial comparing oral capecitabine (Xeloda) with paclitaxel in patients with metastatic/advanced breast cancer pretreated with anthracyclines. Br J Cancer 86:1367-1372.
-
(2002)
Br J Cancer
, vol.86
, pp. 1367-1372
-
-
Talbot, D.C.1
Moiseyenko, V.2
Van Belle, S.3
O'Reilly, S.M.4
Alba Conejo, E.5
Ackland, S.6
Eisenberg, P.7
Melnychuk, D.8
Pienkowski, T.9
Burger, H.U.10
Laws, S.11
Osterwalder, B.12
-
23
-
-
0031035181
-
An information-intensive approach to the molecular pharmacology of cancer
-
Weinstein, J.N., Myers, T.G., O'Connor, P.M., Friend, S.H., Fornace, A.J. Jr., Kohn, K.W., Fojo, T., Bates, S.E., Rubinstein, L.V., Anderson, N.L., Buolamwini, J.K., van Osdol, W.W., Monks, A.P., Scudiero, D.A., Sausville, E.A., Zaharevitz, D.W., Bunow, B., Viswanadhan, V.N., Johnson, G.S., Wittes, R.E. and Paull, K.D. (1997) An information-intensive approach to the molecular pharmacology of cancer. Science 275:343-349.
-
(1997)
Science
, vol.275
, pp. 343-349
-
-
Weinstein, J.N.1
Myers, T.G.2
O'Connor, P.M.3
Friend, S.H.4
Fornace Jr., A.J.5
Kohn, K.W.6
Fojo, T.7
Bates, S.E.8
Rubinstein, L.V.9
Anderson, N.L.10
Buolamwini, J.K.11
Van Osdol, W.W.12
Monks, A.P.13
Scudiero, D.A.14
Sausville, E.A.15
Zaharevitz, D.W.16
Bunow, B.17
Viswanadhan, V.N.18
Johnson, G.S.19
Wittes, R.E.20
Paull, K.D.21
more..
-
24
-
-
0017369396
-
Metabolism of 5-fluorouracil in sensitive and resistant Novikoff hepatoma cells
-
Wilkinson, D.S. and Crumley, J. (1977) Metabolism of 5-fluorouracil in sensitive and resistant Novikoff hepatoma cells. J Biol Chem 252:1051-1056.
-
(1977)
J Biol Chem
, vol.252
, pp. 1051-1056
-
-
Wilkinson, D.S.1
Crumley, J.2
-
25
-
-
0035160330
-
Mechanisms of ErbB2-mediated paclitaxel resistance and trastuzumab-mediated paclitaxel sensitization in ErbB2-overexpressing breast cancers
-
Yu, D. (2001) Mechanisms of ErbB2-mediated paclitaxel resistance and trastuzumab-mediated paclitaxel sensitization in ErbB2-overexpressing breast cancers. Semin Oncol 28:12-17.
-
(2001)
Semin Oncol
, vol.28
, pp. 12-17
-
-
Yu, D.1
-
26
-
-
0034222135
-
Role of erbB2 in breast cancer chemosensitivity
-
Yu, D. and Hung, M.C. (2000) Role of erbB2 in breast cancer chemosensitivity. Bioessays 22:673-680.
-
(2000)
Bioessays
, vol.22
, pp. 673-680
-
-
Yu, D.1
Hung, M.C.2
|