Nucleophosmin (NPM1/B23) interacts with activating transcription factor 5 (ATF5) protein and promotes proteasome- and caspase-dependent ATF5 degradation in hepatocellular carcinoma cells

Journal of Biological Chemistry

Volumn 287, Issue 23, 2012, Pages 19599-19609

  Liu, Xijun ^a   Liu, Dan ^a   Qian, Dongmeng ^b   Dai, Jenny ^a   An, Yi ^b   Jiang, Shaoyan ^b   Stanley, Bruce ^a   Yang, Jinming ^a   Wang, Bin ^b   Liu, Xinyuan ^c,d   Liu, David X ^a,d  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b QINGDAO UNIVERSITY   (China)

^c INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^d ZHEJIANG SCI TECH UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR; C-TERMINAL REGIONS; CELL CYCLE; DOWN-REGULATION; GENE TRANSCRIPTIONS; HEPATOCELLULAR; HEPATOCELLULAR CARCINOMA CELL; HEPATOCYTES; LEUCINE ZIPPERS; MECHANISTIC LINK; N-TERMINALS; NUCLEOLAR LOCALIZATION; NUCLEOPHOSMIN; POLYUBIQUITINATION; PROTEASOMES; PROTEIN COMPLEXES; PROTEIN DEGRADATION; TANDEM AFFINITY PURIFICATION;

CELL PROLIFERATION; CYTOLOGY; DEGRADATION; DIAGNOSIS; GENES; MASS SPECTROMETRY; OLIGOMERIZATION; OLIGOMERS; TRANSCRIPTION; TRANSCRIPTION FACTORS;

CELLS;

ACTIVATING TRANSCRIPTION FACTOR; ACTIVATING TRANSCRIPTION FACTOR 5; CASPASE; CASPASE 3; CYCLIC AMP; HEAT SHOCK PROTEIN 70; NUCLEOPHOSMIN; PROTEASOME; RIBONUCLEASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CANCER GRADING; CARBOXY TERMINAL SEQUENCE; CARCINOMA CELL; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL PROLIFERATION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; EXPRESSION VECTOR; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MASS SPECTROMETRY; NUCLEOLAR LOCALIZATION SIGNAL; NUCLEOLUS; OLIGOMERIZATION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PURIFICATION; PROTEIN STABILITY; UBIQUITINATION; WESTERN BLOTTING;

ACTIVATING TRANSCRIPTION FACTORS; CARCINOMA, HEPATOCELLULAR; CASPASES; CELL CYCLE CHECKPOINTS; GENE EXPRESSION REGULATION, NEOPLASTIC; HEK293 CELLS; HEP G2 CELLS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; LIVER NEOPLASMS; MUTATION; NEOPLASM PROTEINS; NUCLEAR LOCALIZATION SIGNALS; NUCLEAR PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; RESPONSE ELEMENTS; UBIQUITINATION;

EID: 84861735311     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.363622     Document Type: Article

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