Nucleophosmin mutations in childhood acute myelogenous leukemia with normal karyotype

Blood

Volumn 106, Issue 4, 2005, Pages 1419-1422

  Cazzaniga, Giovanni ^b   Dell'Oro, Maria Grazia ^b   Mecucci, Cristina ^b   Giarin, Emanuela ^b   Masetti, Riccardo ^b   Rossi, Vincenzo ^b   Locatelli, Franco ^b   Martelli, Massimo F ^b   Basso, Giuseppe ^b   Pession, Andrea ^b   Biondi, Andrea ^a   Falini, Brunangelo ^b  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOPHOSMIN;

ACUTE GRANULOCYTIC LEUKEMIA; ADOLESCENT; ADULT; AGE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHILD; FEMALE; FRAMESHIFT MUTATION; GENE; GENE LOCATION; GENE MUTATION; GENETIC MARKER; HUMAN; INFANT; ITALY; KARYOTYPE; MAJOR CLINICAL STUDY; MALE; MUTATIONAL ANALYSIS; NPM1 GENE; PREVALENCE; PRIORITY JOURNAL;

EID: 23744479178     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2005-03-0899     Document Type: Article

References (22)

1. Pui CH, Schrappe M, Ribeiro RC, Niemeyer CM. Childhood and adolescent lymphoid and myeloid leukemia. Hematology (Am Soc Hematol Educ Program). 2004;118-145.
2. Gilliland DG, Jordan CT, Felix CA. The molecular basis of leukemia. Hematology (Am Soc Hematol Educ Program). 2004;80-97.
3. Falini B, Mecucd C, Tiacci E, et al. Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype. N Engl J Med. 2005;352:254-266.
4. Cordell JL, Pulford KA, Bigerna B, et al. Detection of normal and chimeric nucleophosmin in human cells. Blood. 1999;93:632-642.
5. Falini B, Pulford K, Pucciarini A, et al. Lymphomas expressing ALK fusion protein(s) other than NPM-ALK. Blood. 1999;94:3509-3515.
6. Borer RA, Lehner CF, Eppenberger HM, Nigg EA. Major nucleolar proteins shuttle between nucleus and cytoplasm. Cell. 1989;56:379-390.
7. Falini B, Mason DY. Proteins encoded by genes involved in chromosomal alterations in lymphoma and leukemia: clinical value of their detection by immunocytochemistry. Blood. 2002;99:409-426.
8. Morris SW, Kirstein MN, Valentine MB, et al. Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma. Science. 1994;263:1281-1284.
9. Redner RL, Rush EA, Faas S, Rudert WA, Corey SJ. The t(5;17) variant of acute promyelocytic leukemia expresses a nucleophosmin-retinoic acid receptor fusion. Blood. 1996;87:882-886.
10. Yoneda-Kato N, Look AT, Kirstein MN, et al. The t(3;5)(q25.1;q34) of myelodysplastic syndrome and acute myeloid leukemia produces a novel fusion gene, NPM-MLF1. Oncogene. 1996;12:265-275.
11. Bertwistle D, Sugimoto M, Sherr CJ. Physical and functional interactions of the Art tumor suppressor protein with nucleophosmin/B23. Mol Cell Biol. 2004;24:985-996.
12. Brady S, Yu Y, Maggi LB, Weber J. ARF impedes NPM/B23 shuttling in an Mdm2-sensitive tumor suppressor pathway. Mol Cell Biol. 2004;21:9327-9338.
13. Korgaonkar C, Hagen J, Tompkins V, et al. Nucleophosmin (B23) targets ARF to nucleoli and inhibits its function. Mol Cell Biol. 2005;25:1258-1271.
14. Colombo E, Marine JC, Danovi D, Falini B, Pelicci PG. Nucleophosmin regulates the stability and transcriptional activity of p53. Nat Cell Biol. 2002;4:529-533.
15. Grisendi S, Pandolfi PP. NPM mutations in acute myelogenous leukemia. N Engl J Med. 2005;352:291-292.
16. van Dongen JJ, Macintyre EA, Gabert JA, et al. Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease: report of the BIOMED-1 Concerted Action: investigation of minimal residual disease in acute leukemia. Leukemia. 1999;13:1901-1928.
17. Frascella E, Rondelli R, Pigazzi M, et al. Clinical features of childhood acute myeloid leukaemia with specific gene rearrangements. Leukemia. 2004;18:1427-1429.
18. van der Burg M, Poulsen TS, Hunger SP, et al. Split-signal FISH for detection of chromosome aberrations in acute lymphoblastic leukemia. Leukemia. 2004;18:895-908.
19. Arrigoni P, Beretta C, Silvestri D, et al. FLT3 internal tandem duplication in childhood acute myeloid leukaemia: association with hyperleucocytosis in acute promyelocytic leukaemia. Br J Haematol. 2003;120:89-92.
20. Greaves M. Molecular genetics, natural history and the demise of childhood leukaemia. Eur J Cancer. 1999;35:173-185.
21. Kau TR, Way JC, Silver PA. Nuclear transport and cancer: from mechanism to intervention. Nat Rev Cancer. 2004;4:106-117.
22. Beretta C, Gaipa G, Rossi V, et al. Development of a quantitative-PCR method for specific FLT3/ITD monitoring in acute myeloid leukemia. Leukemia. 2004;18:1441-1444.