메뉴 건너뛰기




Volumn 287, Issue 23, 2012, Pages 19266-19274

Regulation of epithelial sodium channel trafficking by proprotein convertase subtilisin/kexin type 9 (PCSK9)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHETIC PATHWAY; CARDIO-VASCULAR DISEASE; CELL SURFACES; CHANNEL NUMBER; EPITHELIAL SODIUM CHANNELS; EXTRACELLULAR DOMAINS; PROTEASOMAL DEGRADATION; SUBTILISIN; XENOPUS OOCYTE;

EID: 84861728908     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.363382     Document Type: Article
Times cited : (83)

References (53)
  • 1
    • 4644268448 scopus 로고    scopus 로고
    • The epithelial sodium channel. From molecule to disease
    • Schild, L. (2004) The epithelial sodium channel. From molecule to disease. Rev. Physiol. Biochem. Pharmacol. 151, 93-107
    • (2004) Rev. Physiol. Biochem. Pharmacol. , vol.151 , pp. 93-107
    • Schild, L.1
  • 2
    • 27844476338 scopus 로고    scopus 로고
    • + channel trafficking
    • + channel trafficking. Endocrinology 146, 5079-5085
    • (2005) Endocrinology , vol.146 , pp. 5079-5085
    • Snyder, P.M.1
  • 6
    • 0030068024 scopus 로고    scopus 로고
    • Molecular genetics of human blood pressure variation
    • Lifton, R. P. (1996) Molecular genetics of human blood pressure variation. Science 272, 676-680
    • (1996) Science , vol.272 , pp. 676-680
    • Lifton, R.P.1
  • 9
    • 68949094195 scopus 로고    scopus 로고
    • ENaC at the cutting edge: Regulation of epithelial sodium channels by proteases
    • Kleyman, T. R., Carattino, M. D., and Hughey, R. P. (2009) ENaC at the cutting edge: regulation of epithelial sodium channels by proteases. J. Biol. Chem. 284, 20447-20451
    • (2009) J. Biol. Chem. , vol.284 , pp. 20447-20451
    • Kleyman, T.R.1    Carattino, M.D.2    Hughey, R.P.3
  • 11
    • 0030879756 scopus 로고    scopus 로고
    • An epithelial serine protease activates the amiloride-sensitive sodium channel
    • DOI 10.1038/39329
    • Vallet, V., Chraibi, A., Gaeggeler, H. P., Horisberger, J. D., and Rossier, B. C. (1997) An epithelial serine protease activates the amiloride-sensitive sodium channel. Nature 389, 607-610 (Pubitemid 27446178)
    • (1997) Nature , vol.389 , Issue.6651 , pp. 607-610
    • Vallet, V.1    Chraibi, A.2    Gaeggeler, H.-P.3    Horisberger, J.-D.4    Rossier, B.C.5
  • 16
    • 0036023395 scopus 로고    scopus 로고
    • Na self inhibition of human epithelial Na channel: Temperature dependence and effect of extracellular proteases
    • DOI 10.1085/jgp.20028612
    • Chraïbi, A., and Horisberger, J. D. (2002) Na self-inhibition of human epithelial Na channel. Temperature dependence and effect of extracellular proteases. J. Gen. Physiol. 120, 133-145 (Pubitemid 34857964)
    • (2002) Journal of General Physiology , vol.120 , Issue.2 , pp. 133-145
    • Chraibi, A.1    Horisberger, J.-D.2
  • 17
    • 55549140163 scopus 로고    scopus 로고
    • Intracellular sodium regulates proteolytic activation of the epithelial sodium channel
    • Knight, K. K., Wentzlaff, D. M., and Snyder, P. M. (2008) Intracellular sodium regulates proteolytic activation of the epithelial sodium channel. J. Biol. Chem. 283, 27477-27482
    • (2008) J. Biol. Chem. , vol.283 , pp. 27477-27482
    • Knight, K.K.1    Wentzlaff, D.M.2    Snyder, P.M.3
  • 21
    • 33748778207 scopus 로고    scopus 로고
    • Airway surface liquid volume regulates ENaC by altering the serine protease-protease inhibitor balance: A mechanism for sodium hyperabsorption in cystic fibrosis
    • DOI 10.1074/jbc.M606449200
    • Myerburg, M. M., Butterworth, M. B., McKenna, E. E., Peters, K. W., Frizzell, R. A., Kleyman, T. R., and Pilewski, J. M. (2006) Airway surface liquid volume regulates ENaC by altering the serine protease-protease inhibitor balance. A mechanism for sodium hyperabsorption in cystic fibrosis. J. Biol. Chem. 281, 27942-27949 (Pubitemid 44414506)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.38 , pp. 27942-27949
    • Myerburg, M.M.1    Butterworth, M.B.2    McKenna, E.E.3    Peters, K.W.4    Frizzell, R.A.5    Kleyman, T.R.6    Pilewski, J.M.7
  • 22
    • 33646138489 scopus 로고    scopus 로고
    • Soluble mediators, not cilia, determine airway surface liquid volume in normal and cystic fibrosis superficial airway epithelia
    • Tarran, R., Trout, L., Donaldson, S. H., and Boucher, R. C. (2006) Soluble mediators, not cilia, determine airway surface liquid volume in normal and cystic fibrosis superficial airway epithelia. J. Gen. Physiol. 127, 591-604
    • (2006) J. Gen. Physiol. , vol.127 , pp. 591-604
    • Tarran, R.1    Trout, L.2    Donaldson, S.H.3    Boucher, R.C.4
  • 28
    • 9644266673 scopus 로고    scopus 로고
    • Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver
    • Park, S. W., Moon, Y. A., and Horton, J. D. (2004) Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver. J. Biol. Chem. 279, 50630-50638
    • (2004) J. Biol. Chem. , vol.279 , pp. 50630-50638
    • Park, S.W.1    Moon, Y.A.2    Horton, J.D.3
  • 29
    • 33846679386 scopus 로고    scopus 로고
    • Molecular biology of PCSK9: its role in LDL metabolism
    • DOI 10.1016/j.tibs.2006.12.008, PII S096800040600332X
    • Horton, J. D., Cohen, J. C., and Hobbs, H. H. (2007) Molecular biology of PCSK9. Its role in LDL metabolism. Trends Biochem. Sci. 32, 71-77 (Pubitemid 46199197)
    • (2007) Trends in Biochemical Sciences , vol.32 , Issue.2 , pp. 71-77
    • Horton, J.D.1    Cohen, J.C.2    Hobbs, H.H.3
  • 30
    • 34247899771 scopus 로고    scopus 로고
    • The proprotein convertases are potential targets in the treatment of dyslipidemia
    • DOI 10.1007/s00109-007-0172-7
    • Seidah, N. G., and Prat, A. (2007) The proprotein convertases are potential targets in the treatment of dyslipidemia. J. Mol. Med. 85, 685-696 (Pubitemid 47063524)
    • (2007) Journal of Molecular Medicine , vol.85 , Issue.7 , pp. 685-696
    • Seidah, N.G.1    Prat, A.2
  • 31
    • 17144363236 scopus 로고    scopus 로고
    • Proprotein convertase subtilisin kexin 9: The third locus implicated in autosomal dominant hypercholesterolemia
    • Maxwell, K. N., and Breslow, J. L. (2005) Proprotein convertase subtilisin kexin 9. The third locus implicated in autosomal dominant hypercholesterolemia. Curr. Opin. Lipidol. 16, 167-172 (Pubitemid 40515890)
    • (2005) Current Opinion in Lipidology , vol.16 , Issue.2 , pp. 167-172
    • Maxwell, K.N.1    Breslow, J.L.2
  • 32
    • 33645103550 scopus 로고    scopus 로고
    • Sequence variations in PCSK9, low LDL, and protection against coronary heart disease
    • Cohen, J. C., Boerwinkle, E., Mosley, T. H., Jr., and Hobbs, H. H. (2006) Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. N. Engl. J. Med. 354, 1264-1272
    • (2006) N. Engl. J. Med. , vol.354 , pp. 1264-1272
    • Cohen, J.C.1    Boerwinkle, E.2    Mosley Jr., T.H.3    Hobbs, H.H.4
  • 33
    • 34547137377 scopus 로고    scopus 로고
    • Catalytic activity is not required for secreted PCSK9 to reduce low density lipoprotein receptors in HepG2 cells
    • DOI 10.1074/jbc.C700095200
    • McNutt, M. C., Lagace, T. A., and Horton, J. D. (2007) Catalytic activity is not required for secreted PCSK9 to reduce low density lipoprotein receptors in HepG2 cells. J. Biol. Chem. 282, 20799-20803 (Pubitemid 47099894)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.29 , pp. 20799-20803
    • McNutt, M.C.1    Lagace, T.A.2    Horton, J.D.3
  • 34
  • 35
    • 34547108600 scopus 로고    scopus 로고
    • Binding of proprotein convertase subtilisin/kexin type 9 to epidermal growth factor-like repeat A of low density lipoprotein receptor decreases receptor recycling and increases degradation
    • DOI 10.1074/jbc.M702027200
    • Zhang, D. W., Lagace, T. A., Garuti, R., Zhao, Z., McDonald, M., Horton, J. D., Cohen, J. C., and Hobbs, H. H. (2007) Binding of proprotein convertase subtilisin/kexin type 9 to epidermal growth factor-like repeatAof low density lipoprotein receptor decreases receptor recycling and increases degradation. J. Biol. Chem. 282, 18602-18612 (Pubitemid 47100234)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.25 , pp. 18602-18612
    • Zhang, D.-W.1    Lagace, T.A.2    Garuti, R.3    Zhao, Z.4    McDonald, M.5    Horton, J.D.6    Cohen, J.C.7    Hobbs, H.H.8
  • 38
    • 38349117118 scopus 로고    scopus 로고
    • The proprotein convertase PCSK9 induces the degradation of low density lipoprotein receptor (LDLR) and its closest family members VLDLR and ApoER2
    • Poirier, S., Mayer, G., Benjannet, S., Bergeron, E., Marcinkiewicz, J., Nassoury, N., Mayer, H., Nimpf, J., Prat, A., and Seidah, N. G. (2008) The proprotein convertase PCSK9 induces the degradation of low density lipoprotein receptor (LDLR) and its closest family members VLDLR and ApoER2. J. Biol. Chem. 283, 2363-2372
    • (2008) J. Biol. Chem. , vol.283 , pp. 2363-2372
    • Poirier, S.1    Mayer, G.2    Benjannet, S.3    Bergeron, E.4    Marcinkiewicz, J.5    Nassoury, N.6    Mayer, H.7    Nimpf, J.8    Prat, A.9    Seidah, N.G.10
  • 40
    • 0029005859 scopus 로고
    • Cloning and expression of the β and γ subunits of the human epithelial sodium channel
    • McDonald, F. J., Price, M. P., Snyder, P. M., and Welsh, M. J. (1995) Cloning and expression of the β and γ subunits of the human epithelial sodium channel. Am. J. Physiol. 268, C1157-1163
    • (1995) Am. J. Physiol. , vol.268
    • McDonald, F.J.1    Price, M.P.2    Snyder, P.M.3    Welsh, M.J.4
  • 41
    • 34547107368 scopus 로고    scopus 로고
    • Nedd4-2 catalyzes ubiquitination and degradation of cell surface ENaC
    • DOI 10.1074/jbc.M611329200
    • Zhou, R., Patel, S. V., and Snyder, P. M. (2007) Nedd4-2 catalyzes ubiquitination and degradation of cell surface ENaC. J. Biol. Chem. 282, 20207-20212 (Pubitemid 47100020)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.28 , pp. 20207-20212
    • Zhou, R.1    Patel, S.V.2    Snyder, P.M.3
  • 46
    • 70350399476 scopus 로고    scopus 로고
    • Extracellular chloride regulates the epithelial sodium channel
    • Collier, D. M., and Snyder, P. M. (2009) Extracellular chloride regulates the epithelial sodium channel. J. Biol. Chem. 284, 29320-29325
    • (2009) J. Biol. Chem. , vol.284 , pp. 29320-29325
    • Collier, D.M.1    Snyder, P.M.2
  • 47
    • 79953169501 scopus 로고    scopus 로고
    • +channel (ENaC) intersubunit Cl- inhibitory residues suggests a trimeric αγ β channel architecture
    • +channel (ENaC) intersubunit Cl- inhibitory residues suggests a trimeric αγ β channel architecture. J. Biol. Chem. 286, 6027-6032
    • (2011) J. Biol. Chem. , vol.286 , pp. 6027-6032
    • Collier, D.M.1    Snyder, P.M.2
  • 49
    • 0033986427 scopus 로고    scopus 로고
    • (+) channel to the cell surface
    • (+) channel to the cell surface. J. Clin. Invest. 105, 45-53
    • (2000) J. Clin. Invest. , vol.105 , pp. 45-53
    • Snyder, P.M.1
  • 50
    • 0033664533 scopus 로고    scopus 로고
    • Gating induces a conformational change in the outer vestibule of ENaC
    • Snyder, P. M., Bucher, D. B., and Olson, D. R. (2000) Gating induces a conformational change in the outer vestibule of ENaC. J. Gen. Physiol. 116, 781-790
    • (2000) J. Gen. Physiol. , vol.116 , pp. 781-790
    • Snyder, P.M.1    Bucher, D.B.2    Olson, D.R.3
  • 51
    • 70349323592 scopus 로고    scopus 로고
    • Down-regulating destruction: Phosphorylation regulates the E3 ubiquitin ligase Nedd4-2
    • Snyder, P. M. (2009) Down-regulating destruction: phosphorylation regulates the E3 ubiquitin ligase Nedd4-2. Sci. Signal. 2, pe41
    • (2009) Sci. Signal. , vol.2
    • Snyder, P.M.1
  • 52
    • 79953136043 scopus 로고    scopus 로고
    • A two-step binding model of PCSK9 interaction with the low density lipoprotein receptor
    • Yamamoto, T., Lu, C., and Ryan, R. O. (2011) A two-step binding model of PCSK9 interaction with the low density lipoprotein receptor. J. Biol. Chem. 286, 5464-5470
    • (2011) J. Biol. Chem. , vol.286 , pp. 5464-5470
    • Yamamoto, T.1    Lu, C.2    Ryan, R.O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.