AAV2 mediated retrograde transduction of corticospinal motor neurons reveals initial and selective apical dendrite degeneration in ALS

Neurobiology of Disease

Volumn 47, Issue 2, 2012, Pages 174-183

  Jara, Javier H ^a   Villa, Stephanie R ^a   Khan, Nabil A ^a   Bohn, Martha C ^a   Özdinler, P Hande ^a,b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

ALS; Corticospinal motor neurons; Gene therapy

Indexed keywords

ADENO ASSOCIATED VIRUS 2 VECTOR; COPPER ZINC SUPEROXIDE DISMUTASE; PARVOVIRUS VECTOR; UNCLASSIFIED DRUG;

ADENO ASSOCIATED VIRUS 2 MEDIATED RETROGRADE TRANSDUCTION; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; CELL INTERACTION; CELL POPULATION; CONTROLLED STUDY; CORTICOSPINAL MOTOR NEURON; CYTOARCHITECTURE; DENDRITE; IN VIVO STUDY; MICROGLIA; MOTONEURON; MOTOR CORTEX; MOUSE; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL TRACT; SEROTYPE; TRANSGENIC MOUSE; VIRAL GENE DELIVERY SYSTEM;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; DENDRITES; DEPENDOVIRUS; HEK293 CELLS; HUMANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOTOR NEURONS; PYRAMIDAL TRACTS; SIGNAL TRANSDUCTION;

EID: 84861678410     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2012.03.036     Document Type: Article

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