-
1
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
Sørlie, T.; Perou, C.M.; Tibshiranie, R.; Aas, T.; Geisler, S.; Johnsen, H.; Hastie, T.; Eisen, M. B.; Matt van de Rijn; Jeffrey, S. S.; Thorsen, T.; Quist, H.; Matese, J. C.; Brown, P. O.; Botstein. D.; Lønning, P. E.; Børresen-Dale, A. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc. Natl. Acad. Sci. U S A, 2001, 98(19), 10869-10874.
-
(2001)
Proc. Natl. Acad. Sci. U S A
, vol.98
, Issue.19
, pp. 10869-10874
-
-
Sørlie, T.1
Perou, C.M.2
Tibshiranie, R.3
Aas, T.4
Geisler, S.5
Johnsen, H.6
Hastie, T.7
Eisen, M.B.8
van de Rijn, J.S.S.M.9
Thorsen, T.10
Quist, H.11
Matese, J.C.12
Brown, P.O.13
Botstein, D.14
Lønning, P.E.15
Børresen-Dale, A.16
-
2
-
-
0034680102
-
Molecular portraits of human breast tumors
-
Perou, C. M.; Sørlie, T.; Eisen, M. B.; Matt van de Rijn; Jeffrey, S. S.; Rees, C. A.; Pollack, J. R.; Ross, D. T.; Johnsen, H.; Akslen, L. A.; Fluge, Ø.; Pergamenschikov, A.; Williams, C.; Zhu, S. X.; Lønning, P. E.; Børresen-Dale, A.; Brown, P. O.; Botstein, D. Molecular portraits of human breast tumors. Nature, 2000, 406, 747-752.
-
(2000)
Nature
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
Sørlie, T.2
Eisen, M.B.3
van de Rijn, J.S.S.M.4
Rees, C.A.5
Pollack, J.R.6
Ross, D.T.7
Johnsen, H.8
Akslen, L.A.9
Fluge, Ø.10
Pergamenschikov, A.11
Williams, C.12
Zhu, S.X.13
Lønning, P.E.14
Børresen-Dale, A.15
Brown, P.O.16
Botstein, D.17
-
3
-
-
0037478605
-
Repeated observation of breast tumor subtypes in independent gene expression data sets
-
Sørlie, T.; Tibshirani, R.; Parker, J.; Hastie, T.; Marron, J. S.; Nobel, A.; Deng, S.; Johnsen, H., Pesich, R.; Geisler, S.; Demeter, J.; Perou, C. M.; Lønning, P. E.; Brown, P. O.; Børresen-Dale, A. Botstein, D. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc. Natl. Acad. Sci. U S A, 2003, 100(14), 8418-8423.
-
(2003)
Proc. Natl. Acad. Sci. U S A
, vol.100
, Issue.14
, pp. 8418-8423
-
-
Sørlie, T.1
Tibshirani, R.2
Parker, J.3
Hastie, T.4
Marron, J.S.5
Nobel, A.6
Deng, S.7
Johnsen, H.8
Pesich, R.9
Geisler, S.10
Demeter, J.11
Perou, C.M.12
Lønning, P.E.13
Brown, P.O.14
Børresen-Dale, A.15
Botstein, D.16
-
4
-
-
33744960226
-
Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study
-
Carey, L. A.; Perou, C. M.; Livasy, C. A.; Dressler, L. G.; Cowan, D.; Conway, K.; Karaca, G.; Troester, M. A.; Tse, C. K.; Edmiston, S.; Deming, S. L.; Geradts, J.; Cheang, M. C. U.; Nielsen, T. O.; Moorman, P. G.; Earp, H. S.; Millikan, R. C. Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. JAMA, 2006, 295(21), 2492-2502.
-
(2006)
JAMA
, vol.295
, Issue.21
, pp. 2492-2502
-
-
Carey, L.A.1
Perou, C.M.2
Livasy, C.A.3
Dressler, L.G.4
Cowan, D.5
Conway, K.6
Karaca, G.7
Troester, M.A.8
Tse, C.K.9
Edmiston, S.10
Deming, S.L.11
Geradts, J.12
Cheang, M.C.U.13
Nielsen, T.O.14
Moorman, P.G.15
Earp, H.S.16
Millikan, R.C.17
-
5
-
-
67349148556
-
Pattern of metastatic spread in triple-negative breast cancer
-
Dent, R.; Hanna, W. M.; Trudeau, M.; Rawlinson, E.; Sun, P.; Narod, S. A. Pattern of metastatic spread in triple-negative breast cancer. Breast. Cancer. Res. Treat., 2009, 115, 423-428.
-
(2009)
Breast. Cancer. Res. Treat.
, vol.115
, pp. 423-428
-
-
Dent, R.1
Hanna, W.M.2
Trudeau, M.3
Rawlinson, E.4
Sun, P.5
Narod, S.A.6
-
6
-
-
33645072444
-
Prognostic significance of basallike phenotype and fascin expression in node-negative invasive breast carcinomas
-
Marīa, S.; Pinilla, R.; Sarriō, D.; Honrado, E.; Hardisson, D.; Calero, F.; Benitez, J.; Palacios, J. Prognostic significance of basallike phenotype and fascin expression in node-negative invasive breast carcinomas. Clin. Cancer. Res., 2006, 12(5), 1533-1539.
-
(2006)
Clin. Cancer. Res.
, vol.12
, Issue.5
, pp. 1533-1539
-
-
Maria, S.1
Pinilla, R.2
Sarrio, D.3
Honrado, E.4
Hardisson, D.5
Calero, F.6
Benitez, J.7
Palacios, J.8
-
7
-
-
0029884715
-
Detection and quantitation od HER-2/neu gene amplicatioin in human breast cancer archival material using fluorescence in situ hybridization
-
Plauletti, G.; Godolphin, W.; Press, M. F.; Slamon, D. J. Detection and quantitation od HER-2/neu gene amplicatioin in human breast cancer archival material using fluorescence in situ hybridization. Oncogene. 1996, 13(1), 63-72.
-
(1996)
Oncogene.
, vol.13
, Issue.1
, pp. 63-72
-
-
Plauletti, G.1
Godolphin, W.2
Press, M.F.3
Slamon, D.J.4
-
8
-
-
4143150688
-
Immunohistochemical and Clinical Characterization of the Basal-Like Subtype of Invasive Breast Carcinoma
-
Nielsen, T. O.; Hsu, F. D.; Jensen, K.; Cheang, M.; Karaca, G.; Hu, Z.; Hernandez-Boussard, T.; Livasy, C.; Cowan, D.; Dressler, L.; Akslen, L. A.; Ragaz, J.; Gown, A. M.; Gilks, C. B.; Matt van de Rijn; Perou, C. M. Immunohistochemical and Clinical Characterization of the Basal-Like Subtype of Invasive Breast Carcinoma. Clin. Cancer. Res., 2004, 10(16), 5367-5374.
-
(2004)
Clin. Cancer. Res.
, vol.10
, Issue.16
, pp. 5367-5374
-
-
Nielsen, T.O.1
Hsu, F.D.2
Jensen, K.3
Cheang, M.4
Karaca, G.5
Hu, Z.6
Hernandez-Boussard, T.7
Livasy, C.8
Cowan, D.9
Dressler, L.10
Akslen, L.A.11
Ragaz, J.12
Gown, A.M.13
Gilks, C.B.14
van de Rijn, P.C.M.M.15
-
9
-
-
40349089813
-
Are triple-negative tumors and basal-like breast cancer synonymous?
-
Rakha, E. A.; Tan, D. S.; Foulkes, W. D.; Ellis, L. O.; Tutt, A.; Nielsen, T. O.; Reis-Filho, J. S. Are triple-negative tumors and basal-like breast cancer synonymous?, Breast cancer research, 2007, 9, 404.
-
(2007)
Breast cancer research
, vol.9
, pp. 404
-
-
Rakha, E.A.1
Tan, D.S.2
Foulkes, W.D.3
Ellis, L.O.4
Tutt, A.5
Nielsen, T.O.6
Reis-Filho, J.S.7
-
10
-
-
71049154453
-
Third consensus on medical treatment of metastatic breast cancer
-
for the Central European Cooperative Oncology Group (CECOG)
-
Beslija, S.; Bonneterre, J.; Burstein, H. J.; Cocquyt, V., Gnant, M.; Heinemann, V.; Jassem, J.; Köstler, WJ.; Krainer, M.; Menard, S.; Petit, T.; Petruzelka, L.; Possinger, K.; Schmid, P.; Stadtmauer, E.; Stockler, M.; Belle, S. V.; Vogel, C.; Wilcken., N.; Wiltschke, C.; Zielinski, C. C.; Zwierzina, H. for the Central European Cooperative Oncology Group (CECOG). Third consensus on medical treatment of metastatic breast cancer. Ann. Oncol., 2009, 20, 1771-1785.
-
(2009)
Ann. Oncol.
, vol.20
, pp. 1771-1785
-
-
Beslija, S.1
Bonneterre, J.2
Burstein, H.J.3
Cocquyt, V.4
Gnant, M.5
Heinemann, V.6
Jassem, J.7
Köstler, W.J.8
Krainer, M.9
Menard, S.10
Petit, T.11
Petruzelka, L.12
Possinger, K.13
Schmid, P.14
Stadtmauer, E.15
Stockler, M.16
Belle, S.V.17
Vogel, C.18
Wilcken, N.19
Wiltschke, C.20
Zielinski, C.C.21
Zwierzina, H.22
more..
-
11
-
-
23844549918
-
Breast cancer molecular subtypes respond differently to preoperative chemotherapy
-
Rouzier, R., Perou, C. M.; Symmans, W. F.; Ibrahim, N.; Cristofanilli, M.; Anderson, K.; Hess, K. R.; Stec, J.; Ayers, M.; Wagner, P.; Morandi, C. F.; Rabiul, I.; Ross, J. S.; Hortobagyi, G. N.; Pusztai, L. Breast cancer molecular subtypes respond differently to preoperative chemotherapy. Clin. Cancer Res., 2005, 11(16), 5678-5685.
-
(2005)
Clin. Cancer Res.
, vol.11
, Issue.16
, pp. 5678-5685
-
-
Rouzier, R.1
Perou, C.M.2
Symmans, W.F.3
Ibrahim, N.4
Cristofanilli, M.5
Anderson, K.6
Hess, K.R.7
Stec, J.8
Ayers, M.9
Wagner, P.10
Morandi, C.F.11
Rabiul, I.12
Ross, J.S.13
Hortobagyi, G.N.14
Pusztai, L.15
-
12
-
-
41649102048
-
Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cnacer
-
Liedtke, C.; Mazouni C.; Hess, K. R.; André, F.; Tordai, A.; Meija, J. A.; Symmans, W. F.; Gonzalez-Angulo, A. M.; Hennessy, B.; Cristofanilli, M.; Hortobagyi, G. H.; Pusztai, L. Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cnacer. J. Clin. Oncol., 2008, 26(8), 1275-1281.
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.8
, pp. 1275-1281
-
-
Liedtke, C.1
Mazouni, C.2
Hess, K.R.3
André, F.4
Tordai, A.5
Meija, J.A.6
Symmans, W.F.7
Gonzalez-Angulo, A.M.8
Hennessy, B.9
Cristofanilli, M.10
Hortobagyi, G.H.11
Pusztai, L.12
-
13
-
-
33847063053
-
The Triple Negative Paradox: Primary Tumor Chemosensitivity of Breast Cancer Subtypes
-
Carey, L. A.; Dees, E. C.; Sawyer, L.; Gatti, L.; Moore, D. T.; Collichio, F.; Ollila, D. W.; Sartor, C. I.; Graham, M. L.; Perou, C. M. The Triple Negative Paradox: Primary Tumor Chemosensitivity of Breast Cancer Subtypes. Clin. Cancer Res., 2007, 13(8), 2329-2334.
-
(2007)
Clin. Cancer Res.
, vol.13
, Issue.8
, pp. 2329-2334
-
-
Carey, L.A.1
Dees, E.C.2
Sawyer, L.3
Gatti, L.4
Moore, D.T.5
Collichio, F.6
Ollila, D.W.7
Sartor, C.I.8
Graham, M.L.9
Perou, C.M.10
-
14
-
-
0035902108
-
Genome maintenance mechanisms for preventing cancer
-
Hoeijmakers, J. H. J. Genome maintenance mechanisms for preventing cancer. Nature, 2001, 411, 366-374.
-
(2001)
Nature
, vol.411
, pp. 366-374
-
-
Hoeijmakers, J.H.J.1
-
15
-
-
64849095109
-
Understanding DNA Damage Response and DNA Repair Rathways: Applications to More Targeted Cancer Therapeutics
-
Kinsella, T. J. Understanding DNA Damage Response and DNA Repair Rathways: Applications to More Targeted Cancer Therapeutics. Semin. Oncol., 2009, 36(1), 42-51.
-
(2009)
Semin. Oncol.
, vol.36
, Issue.1
, pp. 42-51
-
-
Kinsella, T.J.1
-
16
-
-
0037268338
-
The Fanconi anaemia/BRCA pathway
-
D'Andrea, A. D.; Grompe, M. The Fanconi anaemia/BRCA pathway. Nature Reviews, 2003, 3, 23-24.
-
(2003)
Nature Reviews
, vol.3
, pp. 23-24
-
-
D'Andrea, A.D.1
Grompe, M.2
-
17
-
-
0036893150
-
The relationship between the roles of BRCA genes in DNA repair and cancer predisposition
-
Tutt, A.; Ashworth, A. The relationship between the roles of BRCA genes in DNA repair and cancer predisposition. Trends in Molecular Medicine, 2002, 8(12), 571-576.
-
(2002)
Trends in Molecular Medicine
, vol.8
, Issue.12
, pp. 571-576
-
-
Tutt, A.1
Ashworth, A.2
-
18
-
-
34248170114
-
Meta-analysis of BRCA1 and BRCA2 penetrance
-
Chen, S.; Parmigiani, G. Meta-analysis of BRCA1 and BRCA2 penetrance. J. Clin. Oncol., 2007, 25(11), 1329-1333.
-
(2007)
J. Clin. Oncol.
, vol.25
, Issue.11
, pp. 1329-1333
-
-
Chen, S.1
Parmigiani, G.2
-
19
-
-
68149100794
-
Triple-negative breast cancer: Novel therapies and new directions
-
Pal, S. K.; Mortimer, J. Triple-negative breast cancer: Novel therapies and new directions. Maturitas, 2009, 63, 269-274.
-
(2009)
Maturitas
, vol.63
, pp. 269-274
-
-
Pal, S.K.1
Mortimer, J.2
-
20
-
-
33749022506
-
Basal-like breast cancer and the BRCA1 phenotypes
-
Turner, N. C.; Reis-Filho, J. S. Basal-like breast cancer and the BRCA1 phenotypes. Oncogene, 2006, 25, 5846-5853.
-
(2006)
Oncogene
, vol.25
, pp. 5846-5853
-
-
Turner, N.C.1
Reis-Filho, J.S.2
-
21
-
-
52049086689
-
Clinical and pathologic Characteristics of patients with BRCApositive and BRCA-negative breast cancer
-
Atchley, D. P.; Albarracin, C. T.; Lopez, A.; Valero, V.; Amos, C. I., Gonzalez-Angulo, A. M.; Hortobagyi, G. N.; Arun, B. K. Clinical and pathologic Characteristics of patients with BRCApositive and BRCA-negative breast cancer. J. Clin. Oncol., 2008, 26(26), 4282-4288.
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.26
, pp. 4282-4288
-
-
Atchley, D.P.1
Albarracin, C.T.2
Lopez, A.3
Valero, V.4
Amos, C.I.5
Gonzalez-Angulo, A.M.6
Hortobagyi, G.N.7
Arun, B.K.8
-
22
-
-
77954633734
-
Triplenegative breast cancer
-
Bartsch, R.; Ziebermayr, R.; Zielinski, C. C.; Steger, G. G. Triplenegative breast cancer. Wien Med Wochenschr, 2010, 160(7-8), 174-181.
-
(2010)
Wien Med Wochenschr
, vol.160
, Issue.7-8
, pp. 174-181
-
-
Bartsch, R.1
Ziebermayr, R.2
Zielinski, C.C.3
Steger, G.G.4
-
23
-
-
4944229642
-
Hallmarks of 'BRCAness' in sporadic cancers
-
Turner, N.; Tutt, A.; Ashworth, A. Hallmarks of 'BRCAness' in sporadic cancers. Nature Reviews, 2004, 4, 1-6.
-
(2004)
Nature Reviews
, vol.4
, pp. 1-6
-
-
Turner, N.1
Tutt, A.2
Ashworth, A.3
-
24
-
-
17244373777
-
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
-
Farmer, H.; McCabe, N.; Lord, C. J.; Tutt, A. N. J.; Johnson, D. A.; Richardson, T. B.; Santarosa, M.; Dillon, K. J.; Hickson, I., Knights, C.; Martin, N. B. M.; Jackson, S. P.; Smith, G. C. M.; Ashworth, A. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature, 2005, 434, 917-921
-
(2005)
Nature
, vol.434
, pp. 917-921
-
-
Farmer, H.1
McCabe, N.2
Lord, C.J.3
Tutt, A.N.J.4
Johnson, D.A.5
Richardson, T.B.6
Santarosa, M.7
Dillon, K.J.8
Hickson, I.9
Knights, C.10
Martin, N.B.M.11
Jackson, S.P.12
Smith, G.C.M.13
Ashworth, A.14
-
25
-
-
0028865245
-
Posttranslational modification of poly (ADPribose) polymerase induced by DNA strand breaks
-
Lindahl, T.; Satoh, M. S.; Poirier, G. G.; Klungland, A. Posttranslational modification of poly (ADPribose) polymerase induced by DNA strand breaks. Trends. Biochem. Sci., 1995, 20, 405-411.
-
(1995)
Trends. Biochem. Sci.
, vol.20
, pp. 405-411
-
-
Lindahl, T.1
Satoh, M.S.2
Poirier, G.G.3
Klungland, A.4
-
26
-
-
0033198919
-
Poly (ADP-ribosyl)ation reactions in the regulation of nuclear functions
-
D'Amours, D.; Desnoyers, S.; D'Silva, I.; Poirier, G. G. Poly (ADP-ribosyl)ation reactions in the regulation of nuclear functions. Biochem. J., 1999, 243, 249-268.
-
(1999)
Biochem. J.
, vol.243
, pp. 249-268
-
-
D'Amours, D.1
Desnoyers, S.2
D'Silva, I.3
Poirier, G.G.4
-
27
-
-
0142009654
-
A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage
-
EL-Khamisy, S. F.; Masutani, M.; Suzuki, H.; Caldecott, K. W. A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage. Nucleic. Acids. Res., 2003, 31(19), 5521-5533.
-
(2003)
Nucleic. Acids. Res.
, vol.31
, Issue.19
, pp. 5521-5533
-
-
El-Khamisy, S.F.1
Masutani, M.2
Suzuki, H.3
Caldecott, K.W.4
-
28
-
-
58149359842
-
Triple-negative breast cancer: Risk factors to potential targets
-
Schneider, B. P.; Winer, E. P.; Foulkes, W.; D.; Garber, J.; Perou, C. M.; Richardson, A.; Sledge, G. W.; Carey, L. A. Triple-negative breast cancer: risk factors to potential targets. Clin. Cancer. Res., 2008, 14(24), 8010-8018.
-
(2008)
Clin. Cancer. Res.
, vol.14
, Issue.24
, pp. 8010-8018
-
-
Schneider, B.P.1
Winer, E.P.2
Foulkes, W.D.3
Garber, J.4
Perou, C.M.5
Richardson, A.6
Sledge, G.W.7
Carey, L.A.8
-
29
-
-
77950023283
-
PARP inhibition: PARP1 and beyond
-
Rouleau, M.; Patel, A.; Hendzel, M. J.; Kaufmann, S. H.; Poirei, G. G. PARP inhibition: PARP1 and beyond. Nature, 2010, 10, 293-301.
-
(2010)
Nature
, vol.10
, pp. 293-301
-
-
Rouleau, M.1
Patel, A.2
Hendzel, M.J.3
Kaufmann, S.H.4
Poirei, G.G.5
-
30
-
-
34548183836
-
PolyADP-ribosylation and cancer
-
Miwa, M.; Masutani, M. PolyADP-ribosylation and cancer. Cancer, Sci., 2007, 98(10), 1528-1535.
-
(2007)
Cancer, Sci.
, vol.98
, Issue.10
, pp. 1528-1535
-
-
Miwa, M.1
Masutani, M.2
-
31
-
-
80054869232
-
PARP inhibitors-current status and the walk towards early breast cancer
-
Glendenning, J.; Tutt, A. PARP inhibitors-current status and the walk towards early breast cancer. Breast, 20, 12-19.
-
Breast
, vol.20
, pp. 12-19
-
-
Glendenning, J.1
Tutt, A.2
-
32
-
-
34249006299
-
ABT-888, an orally active poly(ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models
-
Donawho, C. K.; Luo, Y.; Luo, Y.; Penning, T. D.; Bauch, J. L.; Bouska, J. J.; Bontcheva-Diaz, V. D.; Cox, B. F.; DeWeese, T. L.; Dillehay, L. E.; Ferguson, D. C.; Ghoreishi-Haack, N. S. Grimm, D. R. Guan, R.; Han, E. K.; Holley-Shanks, R. R.; Hristov, B.; Idler, K. B.; Jarvis, K.; Johnson, E. F.; Kleinberg, L. R.; Klinghofer, V.; Lasko, L. M.; Liu, X.; Marsh, K. C.; McGonigal, T. P.; Meulbroek, J. A.; Olson, A. M.; Palma, J. P.; Rodriguez, L. E.; Shi, Y.; Stavropoulos, J. A.; Tsurutani, A. C., Zhu, G. D.; Rosenberg, S. H.; Giranda, V. L.; Frost, D. J. ABT-888, an orally active poly(ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models. Clin. Cancer Res., 2007, 13(9), 2728-2738.
-
(2007)
Clin. Cancer Res.
, vol.13
, Issue.9
, pp. 2728-2738
-
-
Donawho, C.K.1
Luo, Y.2
Luo, Y.3
Penning, T.D.4
Bauch, J.L.5
Bouska, J.J.6
Bontcheva-Diaz, V.D.7
Cox, B.F.8
DeWeese, T.L.9
Dillehay, L.E.10
Ferguson, D.C.11
Ghoreishi-Haack, N.S.12
Grimm, D.R.13
Guan, R.14
Han, E.K.15
Holley-Shanks, R.R.16
Hristov, B.17
Idler, K.B.18
Jarvis, K.19
Johnson, E.F.20
Kleinberg, L.R.21
Klinghofer, V.22
Lasko, L.M.23
Liu, X.24
Marsh, K.C.25
McGonigal, T.P.26
Meulbroek, J.A.27
Olson, A.M.28
Palma, J.P.29
Rodriguez, L.E.30
Shi, Y.31
Stavropoulos, J.A.32
Tsurutani, A.C.33
Zhu, G.D.34
Rosenberg, S.H.35
Giranda, V.L.36
Frost, D.J.37
more..
-
33
-
-
78751610848
-
Iniparib plus chemotherapy in metastatic triple-negative breast cancer
-
O'Shaughnessy, J.; Osborne, C.; Pippen, J. E.; Yoffe, M.; Patt, D.; Rocha, C.; Koo, C. K.; Sherman, B. M.; Bradley, C. Iniparib plus chemotherapy in metastatic triple-negative breast cancer. N. Engl. J. Med., 2011, 364(3), 205-214.
-
(2011)
N. Engl. J. Med.
, vol.364
, Issue.3
, pp. 205-214
-
-
O'Shaughnessy, J.1
Osborne, C.2
Pippen, J.E.3
Yoffe, M.4
Patt, D.5
Rocha, C.6
Koo, C.K.7
Sherman, B.M.8
Bradley, C.9
-
34
-
-
67650471685
-
Inhibition of poly(ADP-ribose)polymerase in tumors from BRCA mutation carriers
-
Fong, P. C.; Boss, D. S.; Yap, T. A.; Tutt, A.; Wu, P.; Mergui-Roelvink, M.; Mortimer, P.; Swaisland, H.; Lau, A.; O'Connor, M. J.; Ashworth, A.; Carmichael, J.; Kaye, S. B.; Schellens, J. H. M.; de Bono, J. S. Inhibition of poly(ADP-ribose)polymerase in tumors from BRCA mutation carriers. N. Engl. J. Med., 2009, 361(2), 123-134.
-
(2009)
N. Engl. J. Med.
, vol.361
, Issue.2
, pp. 123-134
-
-
Fong, P.C.1
Boss, D.S.2
Yap, T.A.3
Tutt, A.4
Wu, P.5
Mergui-Roelvink, M.6
Mortimer, P.7
Swaisland, H.8
Lau, A.9
O'Connor, M.J.10
Ashworth, A.11
Carmichael, J.12
Kaye, S.B.13
Schellens, J.H.M.14
de Bono, J.S.15
-
35
-
-
77955019276
-
Oral Poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: A proof-of-concept trial
-
Tutt, A.; Robson, M.; Garber, J. E.; Domchek, S. M.; Audeh, M. W.; Weitzel, J, N.; Friedlander, M.; Arun, B.; Loman, N.; Schmutzler, R. K.; Wardley, A.; Mitchell, G.; Earl, H.; Wickens, M.; Carmichael, J. Oral Poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial. Lancet, 2010, 376(24), 235-244.
-
(2010)
Lancet
, vol.376
, Issue.24
, pp. 235-244
-
-
Tutt, A.1
Robson, M.2
Garber, J.E.3
Domchek, S.M.4
Audeh, M.W.5
Weitzel, J.N.6
Friedlander, M.7
Arun, B.8
Loman, N.9
Schmutzler, R.K.10
Wardley, A.11
Mitchell, G.12
Earl, H.13
Wickens, M.14
Carmichael, J.15
-
36
-
-
39849097680
-
Resistance to therapy caused by intragenic deletion in BRCA2
-
Edwards, S. L.; Brough, R,.; Lord, C. J., Natrajan, R.; Vatcheva, R.; Levine, D. A.; Boyd, J.; Reis-Filho, J. S.; Ashworth, A. Resistance to therapy caused by intragenic deletion in BRCA2. Nature, 2008, 451, 1111-1115.
-
(2008)
Nature
, vol.451
, pp. 1111-1115
-
-
Edwards, S.L.1
Brough, R.2
Lord, C.J.3
Natrajan, R.4
Vatcheva, R.5
Levine, D.A.6
Boyd, J.7
Reis-Filho, J.S.8
Ashworth, A.9
-
37
-
-
39849106300
-
Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers
-
Sakai, W.; Swisher, E. M.; Karlan, B. Y.; Agarwal, M. K.; Higgins, J.; Friedman, C.; Villegas, E.; Jacquemont, C.; Farrugia, D. J.; Couch, F. J.; Urban, N.; Taniguchi, T. Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers. Nature, 2008, 1116-1120.
-
(2008)
Nature
, pp. 1116-1120
-
-
Sakai, W.1
Swisher, E.M.2
Karlan, B.Y.3
Agarwal, M.K.4
Higgins, J.5
Friedman, C.6
Villegas, E.7
Jacquemont, C.8
Farrugia, D.J.9
Couch, F.J.10
Urban, N.11
Taniguchi, T.12
-
38
-
-
69249100461
-
Functional restoration of BRCA2 protein by secondary BRCA2 mutations in BRCA2-mutated ovarian carcinoma
-
Sakai, W.; Swisher, E. M.; Jacquemont, C.; Chandramohan, K. V.; Couch, F. J.; Langdon, S. P.; Wurz, K.; Higgins, J.; Villegas, E.; Taniguchi, T. Functional restoration of BRCA2 protein by secondary BRCA2 mutations in BRCA2-mutated ovarian carcinoma. Cancer Res., 2009, 69(16), 6381-6386.
-
(2009)
Cancer Res.
, vol.69
, Issue.16
, pp. 6381-6386
-
-
Sakai, W.1
Swisher, E.M.2
Jacquemont, C.3
Chandramohan, K.V.4
Couch, F.J.5
Langdon, S.P.6
Wurz, K.7
Higgins, J.8
Villegas, E.9
Taniguchi, T.10
-
39
-
-
42349096328
-
Secondary BRCA1 mutations in BRCA1-mutated ovarian carcinomas with platinum resistance
-
Swisher, E. M.; Sakai, W.; Karlan, B. Y.; Wurz, K.; Urban, N.; Taniguchi, T. Secondary BRCA1 mutations in BRCA1-mutated ovarian carcinomas with platinum resistance. Cancer Res., 2008, 68(8), 2581-2586.
-
(2008)
Cancer Res.
, vol.68
, Issue.8
, pp. 2581-2586
-
-
Swisher, E.M.1
Sakai, W.2
Karlan, B.Y.3
Wurz, K.4
Urban, N.5
Taniguchi, T.6
-
40
-
-
77954032829
-
Poly(ADP)-ribose polymerase inhibition: Frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval
-
Fong, P. C.; Yap, T. A.; Boss, D. S.; Carden, C. P.; Mergui-Roelvink, M.; Gourley, C.; Greve, J. D.; Lubinski, J.; Shanley, S.; Messiou, C.; A'Hern, R.; Tutt, A.; Ashworth, A.; Stone, J.; Carmichael, J.; Schellens, J. H. M.; deBono J. S.; Kaye, S. B. Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval. J. Clin. Oncol., 2010, 28(15), 2512-2519.
-
(2010)
J. Clin. Oncol.
, vol.28
, Issue.15
, pp. 2512-2519
-
-
Fong, P.C.1
Yap, T.A.2
Boss, D.S.3
Carden, C.P.4
Mergui-Roelvink, M.5
Gourley, C.6
Greve, J.D.7
Lubinski, J.8
Shanley, S.9
Messiou, C.10
A'Hern, R.11
Tutt, A.12
Ashworth, A.13
Stone, J.14
Carmichael, J.15
Schellens, J.H.M.16
deBono, J.S.17
Kaye, S.B.18
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