Modulation of spinal GABAergic analgesia by inhibition of chloride extrusion capacity in mice

Journal of Pain

Volumn 13, Issue 6, 2012, Pages 546-554

  Asiedu, Marina N ^a   Mejia, Galo ^a   Ossipov, Michael K ^a   Malan, T Phillip ^a   Kaila, Kai ^b   Price, Theodore J ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

benzodiazepine; GABA; ganaxolone; KCC2; neuropathic pain; tail flick assay; THIP

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; [(DIHYDROINDENYL)OXY]ALKANOIC ACID; CHLORIDE; CLONIDINE; GABOXADOL; GANAXOLONE; MIDAZOLAM; MUSCIMOL; POTASSIUM CHLORIDE COTRANSPORTER; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; Z 3 [(AMINOIMINOMETHYL)THIO]PROP 2 ENOIC ACID;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DRUG EFFICACY; GABAERGIC SYSTEM; HYPERSENSITIVITY; MALE; MOUSE; NERVE INJURY; NONHUMAN; SPINAL ANESTHESIA; TAIL FLICK TEST;

ANALGESIA; ANALGESICS; ANIMALS; BENZODIAZEPINES; CHLORIDES; GABA-A RECEPTOR AGONISTS; ISOXAZOLES; MALE; MICE; MICE, INBRED ICR; MUSCIMOL; NEURALGIA; PERIPHERAL NERVE INJURIES; PREGNANOLONE; RECEPTORS, GABA-A; SCIATIC NERVE; SYMPORTERS;

EID: 84861647070     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2012.03.002     Document Type: Article

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