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Volumn 6, Issue 1, 2012, Pages 191-196

Impact of intracerebroventricular obestatin on plasma acyl ghrelin, des-acyl ghrelin and nesfatin-1 levels, and on gastric emptying in rats

Author keywords

Gastric emptying; Ghrelin; Intracerebroventricular; Nesfatin 1; Obestatin

Indexed keywords

ACYL GHRELIN; DES ACYL GHRELIN; GHRELIN; NESFATIN 1; OBESTATIN; PEPTIDE; UNCLASSIFIED DRUG;

EID: 84861645993     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2012.901     Document Type: Article
Times cited : (18)

References (52)
  • 1
    • 27744600963 scopus 로고    scopus 로고
    • Medicine: Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake
    • DOI 10.1126/science.1117255
    • Zhang JV, Ren PG, Avsian-Kretchmer O, et al: Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake. Science 310: 996-999, 2005. (Pubitemid 41611907)
    • (2005) Science , vol.310 , Issue.5750 , pp. 996-999
    • Zhang, J.V.1    Ren, P.-G.2    Avsian-Kretchmer, O.3    Luo, C.-W.4    Rauch, R.5    Klein, C.6    Hsueh, A.J.W.7
  • 2
    • 33744466554 scopus 로고    scopus 로고
    • GPR39 receptor expression in the mouse brain
    • DOI 10.1097/01.wnr.0000215779.76602.93, PII 0000175620060529000010
    • Jackson VR, Nothacker HP and Civelli O: GPR39 receptor expression in the mouse brain. Neuroreport 17: 813-816, 2006. (Pubitemid 43804760)
    • (2006) NeuroReport , vol.17 , Issue.8 , pp. 813-816
    • Jackson, V.R.1    Nothacker, H.-P.2    Civelli, O.3
  • 3
    • 0031573862 scopus 로고    scopus 로고
    • Cloning and characterization of two human G protein-coupled receptor genes (GPR38 and GPR39) related to the growth hormone secretagogue and neurotensin receptors
    • DOI 10.1006/geno.1997.5069
    • McKee KK, Tan CP, Palyha OC, et al: Cloning and characterization of two human G protein-coupled receptor genes (GPR38 and GPR39) related to the growth hormone secretagogue and neurotensin receptors. Genomics 46: 426-434, 1997. (Pubitemid 28063291)
    • (1997) Genomics , vol.46 , Issue.3 , pp. 426-434
    • McKee, K.K.1    Tan, C.P.2    Palyha, O.C.3    Liu, J.4    Hreniuk, D.L.5    Smith, R.G.6    Howard, A.D.7    Van Der, P.L.H.T.8
  • 6
    • 33846995594 scopus 로고    scopus 로고
    • Comment on 'obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake'
    • Chartrel N, Alvear-Perez R, Leprince J, et al: Comment on 'obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake'. Science 315: 766, 2007.
    • (2007) Science , vol.315 , pp. 766
    • Chartrel, N.1    Alvear-Perez, R.2    Leprince, J.3
  • 7
    • 33846995594 scopus 로고    scopus 로고
    • Response to comment on 'obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake'
    • Zhang JV, Klein C, Ren PG, et al: Response to comment on 'obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake'. Science 315: 766d, 2007.
    • (2007) Science , vol.315
    • Zhang, J.V.1    Klein, C.2    Ren, P.G.3
  • 9
    • 34347254667 scopus 로고    scopus 로고
    • GPR39 splice variants versus antisense gene LYPD1: Expression and regulation in gastrointestinal tract, endocrine pancreas, liver, and white adipose tissue
    • DOI 10.1210/me.2007-0055
    • Egerod KL, Holst B, Petersen PS, Hansen JB, Mulder J, Hökfelt T and Schwartz TW: GPR39 splice variants versus antisense gene LYPD1: expression and regulation in gastrointestinal tract, endocrine pancreas, liver, and white adipose tissue. Mol Endocrinol 21: 1685-1698, 2007. (Pubitemid 47001091)
    • (2007) Molecular Endocrinology , vol.21 , Issue.7 , pp. 1685-1698
    • Egerod, K.L.1    Holst, B.2    Petersen, P.S.3    Hansen, J.B.4    Mulder, J.5    Hokfelt, T.6    Schwartz, T.W.7
  • 12
    • 33745982941 scopus 로고    scopus 로고
    • Obestatin alters sleep in rats
    • DOI 10.1016/j.neulet.2006.05.053, PII S0304394006005568
    • Szentirmai E and Krueger JM: Obestatin alters sleep in rats. Neurosci Lett 404: 222-226, 2006. (Pubitemid 44063607)
    • (2006) Neuroscience Letters , vol.404 , Issue.1-2 , pp. 222-226
    • Szentirmai, E.1    Krueger, J.M.2
  • 15
    • 33847642830 scopus 로고    scopus 로고
    • Obestatin-mediated proliferation of human retinal pigment epithelial cells: Regulatory mechanisms
    • DOI 10.1002/jcp.20925
    • Camiña JP, Campos JF, Caminos JE, Dieguez C and Casanueva FF: Obestatin-mediated proliferation of human retinal pigment epithelial cells: regulatory mechanisms. J Cell Physiol 211: 1-9, 2007. (Pubitemid 46363890)
    • (2007) Journal of Cellular Physiology , vol.211 , Issue.1 , pp. 1-9
    • Camina, J.P.1    Campos, J.F.2    Caminos, J.E.3    Dieguez, C.4    Casanueva, F.F.5
  • 16
    • 78651329957 scopus 로고    scopus 로고
    • Meta-analysis of the relationship between obestatin and ghrelin levels and the ghrelin/obestatin ratio with respect to obesity
    • Zhang N, Yuan C, Li Z, et al: Meta-analysis of the relationship between obestatin and ghrelin levels and the ghrelin/obestatin ratio with respect to obesity. Am J Med Sci 341: 48-55, 2011.
    • (2011) Am J Med Sci , vol.341 , pp. 48-55
    • Zhang, N.1    Yuan, C.2    Li, Z.3
  • 20
    • 77952110441 scopus 로고    scopus 로고
    • Ghrelin, des-acyl ghrelin and obestatin: Regulatory roles on the gastrointestinal motility
    • pii: 305192
    • Fujimiya M, Asakawa A, Ataka K, Chen CY, Kato I and Inui A: Ghrelin, des-acyl ghrelin and obestatin: regulatory roles on the gastrointestinal motility. Int J Pept 2010: pii: 305192, 2010.
    • (2010) Int J Pept , vol.2010
    • Fujimiya, M.1    Asakawa, A.2    Ataka, K.3    Chen, C.Y.4    Kato, I.5    Inui, A.6
  • 21
    • 73449090824 scopus 로고    scopus 로고
    • Ghrelin gene products and the regulation of food intake and gut motility
    • Chen CY, Asakawa A, Fujimiya M, Lee SD and Inui A: Ghrelin gene products and the regulation of food intake and gut motility. Pharmacol Rev 61: 430-481, 2009.
    • (2009) Pharmacol Rev , vol.61 , pp. 430-481
    • Chen, C.Y.1    Asakawa, A.2    Fujimiya, M.3    Lee, S.D.4    Inui, A.5
  • 22
    • 58149466993 scopus 로고    scopus 로고
    • Identification and characterization of nesfatin-1 immunoreactivity in endocrine cell types of the rat gastric oxyntic mucosa
    • Stengel A, Goebel M, Yakubov I, et al: Identification and characterization of nesfatin-1 immunoreactivity in endocrine cell types of the rat gastric oxyntic mucosa. Endocrinology 150: 232-238, 2009.
    • (2009) Endocrinology , vol.150 , pp. 232-238
    • Stengel, A.1    Goebel, M.2    Yakubov, I.3
  • 23
    • 22344435662 scopus 로고    scopus 로고
    • Des-acyl ghrelin acts by CRF type 2 receptors to disrupt fasted stomach motility in conscious rats
    • DOI 10.1053/j.gastro.2005.04.015, PII S0016508505006979
    • Chen CY, Inui A, Asakawa A, et al: Des-acyl ghrelin acts by CRF type 2 receptors to disrupt fasted stomach motility in conscious rats. Gastroenterology 129: 8-25, 2005. (Pubitemid 41002038)
    • (2005) Gastroenterology , vol.129 , Issue.1 , pp. 8-25
    • Chen, C.-Y.1    Inui, A.2    Asakawa, A.3    Fujino, K.4    Kato, I.5    Chen, C.-C.6    Ueno, N.7    Fujimiya, M.8
  • 24
    • 84862181584 scopus 로고    scopus 로고
    • Intracerebroventricular O-n-octanoylated ghrelin and its splice variant-induced feeding is blocked by insulin, independent of obestatin or CRF receptor, in satiated rats
    • Mar 30, (Epub ahead of print). doi:10.1016/j.nut.2011.11.021
    • Chen CY, Tsai CY, Lee WJ, Liaw WJ, Chiang CH, Ho ST and Lee SD: Intracerebroventricular O-n-octanoylated ghrelin and its splice variant-induced feeding is blocked by insulin, independent of obestatin or CRF receptor, in satiated rats. Nutrition: Mar 30, 2012 (Epub ahead of print). doi:10.1016/j.nut.2011.11.021.
    • (2012) Nutrition
    • Chen, C.Y.1    Tsai, C.Y.2    Lee, W.J.3    Liaw, W.J.4    Chiang, C.H.5    Ho, S.T.6    Lee, S.D.7
  • 25
    • 59049092193 scopus 로고    scopus 로고
    • Intracerebroventricular ghrelin enhances non-nutrient semiliquid gastric emptying in fasted conscious rats
    • Chen CY, Doong ML, Chien EJ, et al: Intracerebroventricular ghrelin enhances non-nutrient semiliquid gastric emptying in fasted conscious rats. Gastroenterol J Taiwan 25: 242-248, 2008.
    • (2008) Gastroenterol J Taiwan , vol.25 , pp. 242-248
    • Chen, C.Y.1    Doong, M.L.2    Chien, E.J.3
  • 26
    • 81155130702 scopus 로고    scopus 로고
    • Changes in postprandial gut hormones after metabolic surgery: A comparison of gastric bypass and sleeve gastrectomy
    • Lee WJ, Chen CY, Chong K, Lee YC, Chen SC and Lee SD: Changes in postprandial gut hormones after metabolic surgery: a comparison of gastric bypass and sleeve gastrectomy. Surg Obes Relat Dis 7: 683-690, 2011.
    • (2011) Surg Obes Relat Dis , vol.7 , pp. 683-690
    • Lee, W.J.1    Chen, C.Y.2    Chong, K.3    Lee, Y.C.4    Chen, S.C.5    Lee, S.D.6
  • 27
    • 79953656625 scopus 로고    scopus 로고
    • Centrally administered urocortin 3 inhibits food intake and gastric emptying in mice
    • Ushikai M, Asakawa A, Sakoguchi T, Tanaka C and Inui A: Centrally administered urocortin 3 inhibits food intake and gastric emptying in mice. Endocrine 39: 113-117, 2011.
    • (2011) Endocrine , vol.39 , pp. 113-117
    • Ushikai, M.1    Asakawa, A.2    Sakoguchi, T.3    Tanaka, C.4    Inui, A.5
  • 28
    • 77953526801 scopus 로고    scopus 로고
    • Centrally administered neuromedin S inhibits feeding behavior and gastroduodenal motility in mice
    • Atsuchi K, Asakawa A, Ushikai M, et al: Centrally administered neuromedin S inhibits feeding behavior and gastroduodenal motility in mice. Horm Metab Res 42: 535-538, 2010.
    • (2010) Horm Metab Res , vol.42 , pp. 535-538
    • Atsuchi, K.1    Asakawa, A.2    Ushikai, M.3
  • 30
    • 33846904900 scopus 로고    scopus 로고
    • Obestatin partially affects ghrelin stimulation of food intake and growth hormone secretion in rodents
    • Zizzari P, Longchamps R, Epelbaum J and Bluet-Pajot MT: Obestatin partially affects ghrelin stimulation of food intake and growth hormone secretion in rodents. Endocrinology 148: 1648-1653, 2007.
    • (2007) Endocrinology , vol.148 , pp. 1648-1653
    • Zizzari, P.1    Longchamps, R.2    Epelbaum, J.3    Bluet-Pajot, M.T.4
  • 33
    • 0034731310 scopus 로고    scopus 로고
    • Ghrelin and des-acyl ghrelin: Two major forms of rat ghrelin peptide in gastrointestinal tissue
    • DOI 10.1006/bbrc.2000.4039
    • Hosoda H, Kojima M, Matsuo H and Kangawa K: Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue. Biochem Biophys Res Commun 279: 909-913, 2000. (Pubitemid 32042875)
    • (2000) Biochemical and Biophysical Research Communications , vol.279 , Issue.3 , pp. 909-913
    • Hosoda, H.1    Kojima, M.2    Matsuo, H.3    Kangawa, K.4
  • 35
    • 38849090670 scopus 로고    scopus 로고
    • Identification of the Acyltransferase that Octanoylates Ghrelin, an Appetite-Stimulating Peptide Hormone
    • DOI 10.1016/j.cell.2008.01.017, PII S0092867408001177
    • Yang J, Brown MS, Liang G, Grishin NV and Goldstein JL: Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone. Cell 132: 387-396, 2008. (Pubitemid 351192001)
    • (2008) Cell , vol.132 , Issue.3 , pp. 387-396
    • Yang, J.1    Brown, M.S.2    Liang, G.3    Grishin, N.V.4    Goldstein, J.L.5
  • 37
    • 74149087844 scopus 로고    scopus 로고
    • Ghrelin, des-acyl ghrelin and nesfatin-1 in gastric X/A-like cells: Role as regulators of food intake and body weight
    • Stengel A, Goebel M, Wang L and Taché Y: Ghrelin, des-acyl ghrelin and nesfatin-1 in gastric X/A-like cells: role as regulators of food intake and body weight. Peptides 31: 357-369, 2010.
    • (2010) Peptides , vol.31 , pp. 357-369
    • Stengel, A.1    Goebel, M.2    Wang, L.3    Taché, Y.4
  • 38
    • 78650520206 scopus 로고    scopus 로고
    • Plasma nesfatin-1 concentrations in restricting-type anorexia nervosa
    • Ogiso K, Asakawa A, Amitani H, et al: Plasma nesfatin-1 concentrations in restricting-type anorexia nervosa. Peptides 32: 150-153, 2011.
    • (2011) Peptides , vol.32 , pp. 150-153
    • Ogiso, K.1    Asakawa, A.2    Amitani, H.3
  • 40
    • 39349116256 scopus 로고    scopus 로고
    • Regulation of ingestive behavior, the upper gastrointestinal motility and gastric acid secretion by ghrelin in mammals
    • DOI 10.2174/157340108783497454
    • Chen CY, Fujimiya M, Asakawa A, Lee SD and Inui A: Regulation of ingestive behavior, the upper gastrointestinal motility and gastric acid secretion by ghrelin in mammals. Curr Nutr Food Sci 4: 32-40, 2008. (Pubitemid 351260133)
    • (2008) Current Nutrition and Food Science , vol.4 , Issue.1 , pp. 32-40
    • Chen, C.-Y.1    Fujimiya, M.2    Asakawa, A.3    Lee, S.-D.4    Inui, A.5
  • 41
    • 77952103770 scopus 로고    scopus 로고
    • Modulation of ingestive behavior and gastrointestinal motility by ghrelin in diabetic animals and humans
    • Chen CY, Fujimiya M, Laviano A, Chang FY, Lin HC and Lee SD: Modulation of ingestive behavior and gastrointestinal motility by ghrelin in diabetic animals and humans. J Chin Med Assoc 73: 225-229, 2010.
    • (2010) J Chin Med Assoc , vol.73 , pp. 225-229
    • Chen, C.Y.1    Fujimiya, M.2    Laviano, A.3    Chang, F.Y.4    Lin, H.C.5    Lee, S.D.6
  • 42
    • 84861646378 scopus 로고    scopus 로고
    • Ghrelin and motilin in the gastrointestinal system
    • In press
    • Chen CY and Tsai CY: Ghrelin and motilin in the gastrointestinal system. Curr Pharm Des, 2012 (In press).
    • (2012) Curr Pharm Des
    • Chen, C.Y.1    Tsai, C.Y.2
  • 43
    • 80053339023 scopus 로고    scopus 로고
    • Lack of direct effects of acyl ghrelin, des-acyl ghrelin, and obestatin on rat lower esophageal sphincter motility in vitro
    • Chen CY and Huang SC: Lack of direct effects of acyl ghrelin, des-acyl ghrelin, and obestatin on rat lower esophageal sphincter motility in vitro. J Chin Med Assoc 74: 394-399, 2011.
    • (2011) J Chin Med Assoc , vol.74 , pp. 394-399
    • Chen, C.Y.1    Huang, S.C.2
  • 45
    • 0037592273 scopus 로고    scopus 로고
    • Ghrelin induces fasted motor activity of the gastrointestinal tract in conscious fed rats
    • DOI 10.1113/jphysiol.2003.040600
    • Fujino K, Inui A, Asakawa A, Kihara N, Fujimura M and Fujimiya M: Ghrelin induces fasted motor activity of the gastro-intestinal tract in conscious fed rats. J Physiol 550: 227-240, 2003. (Pubitemid 36869283)
    • (2003) Journal of Physiology , vol.550 , Issue.1 , pp. 227-240
    • Fujino, K.1    Inui, A.2    Asakawa, A.3    Kihara, N.4    Fujimura, M.5    Fujimiya, M.6
  • 47
    • 38049035630 scopus 로고    scopus 로고
    • Preproghrelin-derived peptide, obestatin, fails to influence food intake in lean or obese rodents
    • Gourcerol G, Coskun T, Craft LS, et al: Preproghrelin-derived peptide, obestatin, fails to influence food intake in lean or obese rodents. Obesity 15: 2643-2652, 2007.
    • (2007) Obesity , vol.15 , pp. 2643-2652
    • Gourcerol, G.1    Coskun, T.2    Craft, L.S.3
  • 48
    • 77954082796 scopus 로고    scopus 로고
    • Obestatin inhibits dopamine release in rat hypothalamus
    • Brunetti L, Di Nisio C, Recinella L, et al: Obestatin inhibits dopamine release in rat hypothalamus. Eur J Pharmacol 641: 142-147, 2010.
    • (2010) Eur J Pharmacol , vol.641 , pp. 142-147
    • Brunetti, L.1    Di Nisio, C.2    Recinella, L.3
  • 49
    • 77957596611 scopus 로고    scopus 로고
    • Centrally administered nesfatin-1 inhibits feeding behaviour and gastroduodenal motility in mice
    • Atsuchi K, Asakawa A, Ushikai M, et al: Centrally administered nesfatin-1 inhibits feeding behaviour and gastroduodenal motility in mice. Neuroreport 21: 1008-1011, 2010.
    • (2010) Neuroreport , vol.21 , pp. 1008-1011
    • Atsuchi, K.1    Asakawa, A.2    Ushikai, M.3
  • 51
    • 33644984197 scopus 로고    scopus 로고
    • Urocortin 2 acts centrally to delay gastric emptying through sympathetic pathways while CRF and urocortin 1 inhibitory actions are vagal dependent in rats
    • Czimmer J, Million M and Taché Y: Urocortin 2 acts centrally to delay gastric emptying through sympathetic pathways while CRF and urocortin 1 inhibitory actions are vagal dependent in rats. Am J Physiol Gastrointest Liver Physiol 290: G511-G518, 2006.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290
    • Czimmer, J.1    Million, M.2    Taché, Y.3
  • 52
    • 0026649885 scopus 로고
    • Serial cerebrospinal fluid corticotropin-releasing hormone concentrations in healthy and depressed humans
    • Geracioti TD Jr, Orth DN, Ekhator NN, Blumenkopf B and Loosen PT: Serial cerebrospinal fluid corticotropin-releasing hormone concentrations in healthy and depressed humans. J Clin Endocrinol Metab 74: 1325-1330, 1992.
    • (1992) J Clin Endocrinol Metab , vol.74 , pp. 1325-1330
    • Geracioti Jr., T.D.1    Orth, D.N.2    Ekhator, N.N.3    Blumenkopf, B.4    Loosen, P.T.5


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