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Volumn 28, Issue 7-8, 2012, Pages 812-820

Intracerebroventricular O-n-octanoylated ghrelin and its splice variant-induced feeding is blocked by insulin, independent of obestatin or CRF receptor, in satiated rats

Author keywords

Acyl ghrelin; Corticotropin releasing factor receptor; Des Gln 14 ghrelin; Food intake; Insulin; Intracerebroventricular; Obestatin

Indexed keywords

ASTRESSIN; CORTICOTROPIN RELEASING FACTOR RECEPTOR; DES GLUTAMINE 14 GHRELIN; GHRELIN; INSULIN; O N OCTANOYLATED GHRELIN; OBESTATIN; UNCLASSIFIED DRUG;

EID: 84862181584     PISSN: 08999007     EISSN: 18731244     Source Type: Journal    
DOI: 10.1016/j.nut.2011.11.021     Document Type: Article
Times cited : (16)

References (36)
  • 1
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima M., Hosoda H., Date Y., Nakazato M., Matsuo H., Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 1999, 402:656-660.
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 2
    • 0034698072 scopus 로고    scopus 로고
    • Purification and characterization of rat des-Gln14-Ghrelin, a second endogenous ligand for the growth hormone secretagogue receptor
    • Hosoda H., Kojima M., Matsuo H., Kangawa K. Purification and characterization of rat des-Gln14-Ghrelin, a second endogenous ligand for the growth hormone secretagogue receptor. J Biol Chem 2000, 275:21995-22000.
    • (2000) J Biol Chem , vol.275 , pp. 21995-22000
    • Hosoda, H.1    Kojima, M.2    Matsuo, H.3    Kangawa, K.4
  • 3
    • 73449090824 scopus 로고    scopus 로고
    • Ghrelin gene products and the regulation of food intake and gut motility
    • Chen C.Y., Asakawa A., Fujimiya M., Lee S.D., Inui A. Ghrelin gene products and the regulation of food intake and gut motility. Pharmacol Rev 2009, 61:430-481.
    • (2009) Pharmacol Rev , vol.61 , pp. 430-481
    • Chen, C.Y.1    Asakawa, A.2    Fujimiya, M.3    Lee, S.D.4    Inui, A.5
  • 4
    • 0033711116 scopus 로고    scopus 로고
    • The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion
    • Wren A.M., Small C.J., Ward H.L., Murphy K.G., Dakin C.L., Taheri S., et al. The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion. Endocrinology 2000, 141:4325-4328.
    • (2000) Endocrinology , vol.141 , pp. 4325-4328
    • Wren, A.M.1    Small, C.J.2    Ward, H.L.3    Murphy, K.G.4    Dakin, C.L.5    Taheri, S.6
  • 5
  • 6
    • 79960932903 scopus 로고    scopus 로고
    • Hypothalamic control of lipid metabolism: focus on leptin, ghrelin and melanocortins
    • Diéguez C., Vazquez M.J., Romero A., López M., Nogueiras R. Hypothalamic control of lipid metabolism: focus on leptin, ghrelin and melanocortins. Neuroendocrinology 2011, 94:1-11.
    • (2011) Neuroendocrinology , vol.94 , pp. 1-11
    • Diéguez, C.1    Vazquez, M.J.2    Romero, A.3    López, M.4    Nogueiras, R.5
  • 7
    • 33846540210 scopus 로고    scopus 로고
    • The effect of centrally administered ghrelin on pituitary ACTH cells and circulating ACTH and corticosterone in rats
    • Stevanović D., Milosević V., Starcević V.P., Severs W.B. The effect of centrally administered ghrelin on pituitary ACTH cells and circulating ACTH and corticosterone in rats. Life Sci 2007, 80:867-872.
    • (2007) Life Sci , vol.80 , pp. 867-872
    • Stevanović, D.1    Milosević, V.2    Starcević, V.P.3    Severs, W.B.4
  • 8
    • 17744374270 scopus 로고    scopus 로고
    • Endocrine activities of ghrelin, a natural growth hormone secretagogue (GHS), in humans: comparison and interactions with hexarelin, a nonnatural peptidyl GHS, and GH-releasing hormone
    • Arvat E., Maccario M., Di Vito L., Broglio F., Benso A., Gottero C., et al. Endocrine activities of ghrelin, a natural growth hormone secretagogue (GHS), in humans: comparison and interactions with hexarelin, a nonnatural peptidyl GHS, and GH-releasing hormone. J Clin Endocrinol Metab 2001, 86:1169-1174.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1169-1174
    • Arvat, E.1    Maccario, M.2    Di Vito, L.3    Broglio, F.4    Benso, A.5    Gottero, C.6
  • 9
    • 34548771936 scopus 로고    scopus 로고
    • Putative somatostatin suppression potentiates adrenocorticotropin secretion driven by ghrelin and human corticotropin-releasing hormone
    • Iranmanesh A., Carpenter P.C., Mielke K., Bowers C.Y., Veldhuis J.D. Putative somatostatin suppression potentiates adrenocorticotropin secretion driven by ghrelin and human corticotropin-releasing hormone. J Clin Endocrinol Metab 2007, 92:3653-3659.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 3653-3659
    • Iranmanesh, A.1    Carpenter, P.C.2    Mielke, K.3    Bowers, C.Y.4    Veldhuis, J.D.5
  • 10
    • 17944380559 scopus 로고    scopus 로고
    • A role of ghrelin in neuroendocrine and behavioral responses to stress in mice
    • Asakawa A., Inui A., Kaga T., Yuzuriha H., Nagata T., Fujimiya M., et al. A role of ghrelin in neuroendocrine and behavioral responses to stress in mice. Neuroendocrinology 2001, 74:143-147.
    • (2001) Neuroendocrinology , vol.74 , pp. 143-147
    • Asakawa, A.1    Inui, A.2    Kaga, T.3    Yuzuriha, H.4    Nagata, T.5    Fujimiya, M.6
  • 11
    • 0141786987 scopus 로고    scopus 로고
    • Ghrelin is released from rat hypothalamic explants and stimulates corticotrophin-releasing hormone and arginine-vasopressin
    • Mozid A.M., Tringali G., Forsling M.L., Hendricks M.S., Ajodha S., Edwards R., et al. Ghrelin is released from rat hypothalamic explants and stimulates corticotrophin-releasing hormone and arginine-vasopressin. Horm Metab Res 2003, 35:455-459.
    • (2003) Horm Metab Res , vol.35 , pp. 455-459
    • Mozid, A.M.1    Tringali, G.2    Forsling, M.L.3    Hendricks, M.S.4    Ajodha, S.5    Edwards, R.6
  • 12
    • 27744600963 scopus 로고    scopus 로고
    • Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake
    • Zhang J.V., Ren P.G., Avsian-Kretchmer O., Luo C.W., Rauch R., Klein C., et al. Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake. Science 2005, 310:996-999.
    • (2005) Science , vol.310 , pp. 996-999
    • Zhang, J.V.1    Ren, P.G.2    Avsian-Kretchmer, O.3    Luo, C.W.4    Rauch, R.5    Klein, C.6
  • 14
  • 15
    • 22344435662 scopus 로고    scopus 로고
    • Des-acyl ghrelin acts by CRF type 2 receptors to disrupt fasted stomach motility in conscious rats
    • Chen C.Y., Inui A., Asakawa A., Fujino K., Kato I., Chen C.C., et al. Des-acyl ghrelin acts by CRF type 2 receptors to disrupt fasted stomach motility in conscious rats. Gastroenterology 2005, 129:8-25.
    • (2005) Gastroenterology , vol.129 , pp. 8-25
    • Chen, C.Y.1    Inui, A.2    Asakawa, A.3    Fujino, K.4    Kato, I.5    Chen, C.C.6
  • 16
    • 77952107898 scopus 로고    scopus 로고
    • A novel simultaneous measurement method to assess the influence of intracerebroventricular obestatin on colonic motility and secretion in conscious rats
    • Chen C.Y., Doong M.L., Li C.P., Liaw W.J., Lee H.F., Chang F.Y., et al. A novel simultaneous measurement method to assess the influence of intracerebroventricular obestatin on colonic motility and secretion in conscious rats. Peptides 2010, 31:1113-1117.
    • (2010) Peptides , vol.31 , pp. 1113-1117
    • Chen, C.Y.1    Doong, M.L.2    Li, C.P.3    Liaw, W.J.4    Lee, H.F.5    Chang, F.Y.6
  • 17
    • 59049092193 scopus 로고    scopus 로고
    • Intracerebroventricular ghrelin enhances non-nutrient semiliquid gastric emptying in fasted conscious rats
    • Chen C.Y., Doong M.L., Chien E.J., Luo J.C., Lu C.L., Lin H.C., et al. Intracerebroventricular ghrelin enhances non-nutrient semiliquid gastric emptying in fasted conscious rats. Gastroenterol J Taiwan 2008, 25:242-248.
    • (2008) Gastroenterol J Taiwan , vol.25 , pp. 242-248
    • Chen, C.Y.1    Doong, M.L.2    Chien, E.J.3    Luo, J.C.4    Lu, C.L.5    Lin, H.C.6
  • 18
    • 80053339023 scopus 로고    scopus 로고
    • Lack of direct effects of acyl ghrelin, des-acyl ghrelin, and obestatin on rat lower esophageal sphincter motility in vitro
    • Chen C.Y., Huang S.C. Lack of direct effects of acyl ghrelin, des-acyl ghrelin, and obestatin on rat lower esophageal sphincter motility in vitro. J Chin Med Assoc 2011, 74:394-399.
    • (2011) J Chin Med Assoc , vol.74 , pp. 394-399
    • Chen, C.Y.1    Huang, S.C.2
  • 19
    • 73549099979 scopus 로고    scopus 로고
    • Evaluation of the lack of anorectic effect of intracerebroventricular insulin in rats
    • Jessen L., Clegg D.J., Bouman S.D. Evaluation of the lack of anorectic effect of intracerebroventricular insulin in rats. Am J Physiol Regul Integr Comp Physiol 2010, 298:R43-R50.
    • (2010) Am J Physiol Regul Integr Comp Physiol , vol.298
    • Jessen, L.1    Clegg, D.J.2    Bouman, S.D.3
  • 20
    • 2642565900 scopus 로고    scopus 로고
    • Ghrelin stimulates gastric emptying but is without effect on acid secretion and gastric endocrine cells
    • Dornonville de la Cour C., Lindstrom E., Norlen P., Hakanson R. Ghrelin stimulates gastric emptying but is without effect on acid secretion and gastric endocrine cells. Regul Pept 2004, 120:23-32.
    • (2004) Regul Pept , vol.120 , pp. 23-32
    • Dornonville de la Cour, C.1    Lindstrom, E.2    Norlen, P.3    Hakanson, R.4
  • 21
    • 0142200403 scopus 로고    scopus 로고
    • Cardiac effects of ghrelin and its endogenous derivatives des-octanoyl ghrelin and des-Gln14-ghrelin
    • Bedendi I., Alloatti G., Marcantoni A., Malan D., Catapano F., Ghé C., et al. Cardiac effects of ghrelin and its endogenous derivatives des-octanoyl ghrelin and des-Gln14-ghrelin. Eur J Pharmacol 2003, 476:87-95.
    • (2003) Eur J Pharmacol , vol.476 , pp. 87-95
    • Bedendi, I.1    Alloatti, G.2    Marcantoni, A.3    Malan, D.4    Catapano, F.5    Ghé, C.6
  • 23
    • 33748502704 scopus 로고    scopus 로고
    • Circulating ghrelin concentrations are lowered by intracerebroventricular insulin
    • Ueno M., Carvalheira J.B., Oliveira R.L., Velloso L.A., Saad M.J. Circulating ghrelin concentrations are lowered by intracerebroventricular insulin. Diabetologia 2006, 49:2449-2452.
    • (2006) Diabetologia , vol.49 , pp. 2449-2452
    • Ueno, M.1    Carvalheira, J.B.2    Oliveira, R.L.3    Velloso, L.A.4    Saad, M.J.5
  • 24
    • 18844421372 scopus 로고    scopus 로고
    • Molecular forms of hypothalamic ghrelin and its regulation by fasting and 2-deoxy-d-glucose administration
    • Sato T., Fukue Y., Teranishi H., Yoshida Y., Kojima M. Molecular forms of hypothalamic ghrelin and its regulation by fasting and 2-deoxy-d-glucose administration. Endocrinology 2005, 146:2510-2516.
    • (2005) Endocrinology , vol.146 , pp. 2510-2516
    • Sato, T.1    Fukue, Y.2    Teranishi, H.3    Yoshida, Y.4    Kojima, M.5
  • 25
    • 51449084843 scopus 로고    scopus 로고
    • Pulsatile cerebrospinal fluid and plasma ghrelin in relation to growth hormone secretion and food intake in the sheep
    • Grouselle D., Chaillou E., Caraty A., Bluet-Pajot M.T., Zizzari P., Tillet Y., et al. Pulsatile cerebrospinal fluid and plasma ghrelin in relation to growth hormone secretion and food intake in the sheep. J Neuroendocrinol 2008, 20:1138-1146.
    • (2008) J Neuroendocrinol , vol.20 , pp. 1138-1146
    • Grouselle, D.1    Chaillou, E.2    Caraty, A.3    Bluet-Pajot, M.T.4    Zizzari, P.5    Tillet, Y.6
  • 26
    • 81155130702 scopus 로고    scopus 로고
    • Changes in postprandial gut hormones after metabolic surgery: a comparison of gastric bypass and sleeve gastrectomy
    • Lee W.J., Chen C.Y., Chong K., Lee Y.C., Chen S.C., Lee S.D. Changes in postprandial gut hormones after metabolic surgery: a comparison of gastric bypass and sleeve gastrectomy. Surg Obes Relat Dis 2011, 7:683-690.
    • (2011) Surg Obes Relat Dis , vol.7 , pp. 683-690
    • Lee, W.J.1    Chen, C.Y.2    Chong, K.3    Lee, Y.C.4    Chen, S.C.5    Lee, S.D.6
  • 29
    • 33846995594 scopus 로고    scopus 로고
    • Comment on "obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake"
    • Chartrel N., Alvear-Perez R., Leprince J., Iturrioz X., Reaux-Le Goazigo A., Audinot V., et al. Comment on "obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake" Science 2007, 315:766.
    • (2007) Science , vol.315 , pp. 766
    • Chartrel, N.1    Alvear-Perez, R.2    Leprince, J.3    Iturrioz, X.4    Reaux-Le Goazigo, A.5    Audinot, V.6
  • 31
    • 77952103770 scopus 로고    scopus 로고
    • Modulation of ingestive behavior and gastrointestinal motility by ghrelin in diabetic animals and humans
    • Chen C.Y., Fujimiya M., Laviano A., Chang F.Y., Lin H.C., Lee S.D. Modulation of ingestive behavior and gastrointestinal motility by ghrelin in diabetic animals and humans. J Chin Med Assoc 2010, 73:225-229.
    • (2010) J Chin Med Assoc , vol.73 , pp. 225-229
    • Chen, C.Y.1    Fujimiya, M.2    Laviano, A.3    Chang, F.Y.4    Lin, H.C.5    Lee, S.D.6
  • 32
    • 33751062773 scopus 로고    scopus 로고
    • Central obestatin administration does not modify either spontaneous or ghrelin-induced food intake in rats
    • Seoane L.M., Al-Massadi O., Pazos Y., Pagotto U., Casanueva F.F. Central obestatin administration does not modify either spontaneous or ghrelin-induced food intake in rats. J Endocrinol Invest 2006, 29:RC13-RC15.
    • (2006) J Endocrinol Invest , vol.29
    • Seoane, L.M.1    Al-Massadi, O.2    Pazos, Y.3    Pagotto, U.4    Casanueva, F.F.5
  • 33
    • 0037456519 scopus 로고    scopus 로고
    • The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis
    • Cowley M.A., Smith R.G., Diano S., Tschöp M., Pronchuk N., Grove K.L., et al. The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis. Neuron 2003, 37:649-661.
    • (2003) Neuron , vol.37 , pp. 649-661
    • Cowley, M.A.1    Smith, R.G.2    Diano, S.3    Tschöp, M.4    Pronchuk, N.5    Grove, K.L.6
  • 35
    • 33646083934 scopus 로고    scopus 로고
    • Peripheral ghrelin participates in glucostatic feeding mechanisms and in the anorexigenic signalling mediated by CART and CRF neurons
    • Solomon A., De Fanti B.A., Martínez J.A. Peripheral ghrelin participates in glucostatic feeding mechanisms and in the anorexigenic signalling mediated by CART and CRF neurons. Nutr Neurosci 2005, 8:287-295.
    • (2005) Nutr Neurosci , vol.8 , pp. 287-295
    • Solomon, A.1    De Fanti, B.A.2    Martínez, J.A.3
  • 36
    • 40849116453 scopus 로고    scopus 로고
    • A nonselective corticotropin-releasing hormone receptor antagonist, prevents the inhibitory effect of ghrelin on luteinizing hormone pulse frequency in the ovariectomized rhesus monkey
    • Vulliémoz N.R., Xiao E., Xia-Zhang L., Rivier J., Ferin M., Astressin B. A nonselective corticotropin-releasing hormone receptor antagonist, prevents the inhibitory effect of ghrelin on luteinizing hormone pulse frequency in the ovariectomized rhesus monkey. Endocrinology 2008, 149:869-874.
    • (2008) Endocrinology , vol.149 , pp. 869-874
    • Vulliémoz, N.R.1    Xiao, E.2    Xia-Zhang, L.3    Rivier, J.4    Ferin, M.5    Astressin, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.