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Volumn 518, Issue 1, 2012, Pages 14-18

The effects of chronic copper exposure on the amyloid protein metabolisim associated genes' expression in chronic cerebral hypoperfused rats

Author keywords

Alzheimer's disease; Amyloid protein; Cerebral hypoperfusion; Copper

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BETA SECRETASE 1; COPPER; MESSENGER RNA;

EID: 84861531493     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2012.04.030     Document Type: Article
Times cited : (17)

References (37)
  • 6
    • 0035816661 scopus 로고    scopus 로고
    • A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60
    • Cao X., Sudhof T.C. A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60. Science 2001, 293:115-120.
    • (2001) Science , vol.293 , pp. 115-120
    • Cao, X.1    Sudhof, T.C.2
  • 7
    • 33947646259 scopus 로고    scopus 로고
    • Permanent, bilateral common carotid artery occlusion in the rat: a model for chronic cerebral hypoperfusion-related neurodegenerative diseases
    • Farkas E., Luiten P.G., Bari F. Permanent, bilateral common carotid artery occlusion in the rat: a model for chronic cerebral hypoperfusion-related neurodegenerative diseases. Brain Research Reviews 2007, 54:162-180.
    • (2007) Brain Research Reviews , vol.54 , pp. 162-180
    • Farkas, E.1    Luiten, P.G.2    Bari, F.3
  • 8
    • 33745893209 scopus 로고    scopus 로고
    • Amyloid at the blood vessel wall
    • Hardy J., Cullen K. Amyloid at the blood vessel wall. Nature Medicine 2006, 12:756-757.
    • (2006) Nature Medicine , vol.12 , pp. 756-757
    • Hardy, J.1    Cullen, K.2
  • 9
    • 43349100174 scopus 로고    scopus 로고
    • Neurotoxicological evaluation of long-term lanthanum chloride exposure in rats
    • He X., Zhang Z., Zhang H., Zhao Y., Chai Z. Neurotoxicological evaluation of long-term lanthanum chloride exposure in rats. Toxicological Sciences 2008, 103:354-361.
    • (2008) Toxicological Sciences , vol.103 , pp. 354-361
    • He, X.1    Zhang, Z.2    Zhang, H.3    Zhao, Y.4    Chai, Z.5
  • 10
    • 12144282992 scopus 로고    scopus 로고
    • Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer's Abeta peptides
    • Huang X., Atwood C.S., Moir R.D., Hartshorn M.A., Tanzi R.E., Bush A.I. Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer's Abeta peptides. Journal of Biological Inorganic Chemistry 2004, 9:954-960.
    • (2004) Journal of Biological Inorganic Chemistry , vol.9 , pp. 954-960
    • Huang, X.1    Atwood, C.S.2    Moir, R.D.3    Hartshorn, M.A.4    Tanzi, R.E.5    Bush, A.I.6
  • 12
    • 79952701977 scopus 로고    scopus 로고
    • Chronic mild cerebrovascular dysfunction as a cause for Alzheimer's disease?
    • Humpel C. Chronic mild cerebrovascular dysfunction as a cause for Alzheimer's disease?. Experimental Gerontology 2011, 46:225-232.
    • (2011) Experimental Gerontology , vol.46 , pp. 225-232
    • Humpel, C.1
  • 14
    • 61349110122 scopus 로고    scopus 로고
    • Chronic copper exposure exacerbates both amyloid and tau pathology and selectively dysregulates cdk5 in a mouse model of AD
    • Kitazawa M., Cheng D., LaFerla F.M. Chronic copper exposure exacerbates both amyloid and tau pathology and selectively dysregulates cdk5 in a mouse model of AD. Journal of Neurochemistry 2009, 108:1550-1560.
    • (2009) Journal of Neurochemistry , vol.108 , pp. 1550-1560
    • Kitazawa, M.1    Cheng, D.2    LaFerla, F.M.3
  • 15
    • 79955019165 scopus 로고    scopus 로고
    • Long term changes in phospho-APP and tau aggregation in the 3xTg-AD mice following cerebral ischemia
    • Koike M.A., Garcia F.G., Kitazawa M., Green K.N., Laferla F.M. Long term changes in phospho-APP and tau aggregation in the 3xTg-AD mice following cerebral ischemia. Neuroscience Letters 2011, 495:55-59.
    • (2011) Neuroscience Letters , vol.495 , pp. 55-59
    • Koike, M.A.1    Garcia, F.G.2    Kitazawa, M.3    Green, K.N.4    Laferla, F.M.5
  • 16
    • 59649125004 scopus 로고    scopus 로고
    • Copper suppresses hippocampus LTP in the rat, but does not alter learning or memory in the morris water maze
    • Leiva J., Palestini M., Infante C., Goldschmidt A., Motles E. Copper suppresses hippocampus LTP in the rat, but does not alter learning or memory in the morris water maze. Brain Research 2009, 1256:69-75.
    • (2009) Brain Research , vol.1256 , pp. 69-75
    • Leiva, J.1    Palestini, M.2    Infante, C.3    Goldschmidt, A.4    Motles, E.5
  • 17
    • 45849148467 scopus 로고    scopus 로고
    • Exposure to metal ions regulates mRNA levels of APP and BACE1 in PC12 cells: blockage by curcumin
    • Lin R., Chen X., Li W., Han Y., Liu P., Pi R. Exposure to metal ions regulates mRNA levels of APP and BACE1 in PC12 cells: blockage by curcumin. Neuroscience Letters 2008, 440:344-347.
    • (2008) Neuroscience Letters , vol.440 , pp. 344-347
    • Lin, R.1    Chen, X.2    Li, W.3    Han, Y.4    Liu, P.5    Pi, R.6
  • 19
    • 58549116872 scopus 로고    scopus 로고
    • Trace amounts of copper exacerbate beta amyloid-induced neurotoxicity in the cholesterol-fed mice through TNF-mediated inflammatory pathway
    • Lu J., Wu D.M., Zheng Y.L., Sun D.X., Hu B., Shan Q., Zhang Z.F., Fan S.H. Trace amounts of copper exacerbate beta amyloid-induced neurotoxicity in the cholesterol-fed mice through TNF-mediated inflammatory pathway. Brain, Behavior, and Immunity 2009, 23:193-203.
    • (2009) Brain, Behavior, and Immunity , vol.23 , pp. 193-203
    • Lu, J.1    Wu, D.M.2    Zheng, Y.L.3    Sun, D.X.4    Hu, B.5    Shan, Q.6    Zhang, Z.F.7    Fan, S.H.8
  • 20
    • 54249100455 scopus 로고    scopus 로고
    • Alzheimer's disease: cerebrovascular dysfunction, oxidative stress, and advanced clinical therapies
    • Marlatt M.W., Lucassen P.J., Perry G., Smith M.A., Zhu X. Alzheimer's disease: cerebrovascular dysfunction, oxidative stress, and advanced clinical therapies. Journal of Alzheimer's Disease 2008, 15:199-210.
    • (2008) Journal of Alzheimer's Disease , vol.15 , pp. 199-210
    • Marlatt, M.W.1    Lucassen, P.J.2    Perry, G.3    Smith, M.A.4    Zhu, X.5
  • 21
    • 0043023877 scopus 로고    scopus 로고
    • Neuroscience Possible role for environmental copper in Alzheimer's disease
    • Marx J., Neuroscience Possible role for environmental copper in Alzheimer's disease. Science 2003, 301:905.
    • (2003) Science , vol.301 , pp. 905
    • Marx, J.1
  • 22
    • 67649185049 scopus 로고    scopus 로고
    • Genetics Environmental factors and the emerging role of epigenetics in neurodegenerative diseases
    • Migliore L., Coppede F., Genetics environmental factors and the emerging role of epigenetics in neurodegenerative diseases. Mutation Research 2009, 667:82-97.
    • (2009) Mutation Research , vol.667 , pp. 82-97
    • Migliore, L.1    Coppede, F.2
  • 24
    • 0029935396 scopus 로고    scopus 로고
    • The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I)
    • Multhaup G., Schlicksupp A., Hesse L., Beher D., Ruppert T., Masters C.L., Beyreuther K. The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I). Science 1996, 271:1406-1409.
    • (1996) Science , vol.271 , pp. 1406-1409
    • Multhaup, G.1    Schlicksupp, A.2    Hesse, L.3    Beher, D.4    Ruppert, T.5    Masters, C.L.6    Beyreuther, K.7
  • 25
    • 64749089732 scopus 로고    scopus 로고
    • Copper intoxication; antioxidant defenses and oxidative damage in rat brain
    • Ozcelik D., Uzun H. Copper intoxication; antioxidant defenses and oxidative damage in rat brain. Biological Trace Element Research 2009, 127:45-52.
    • (2009) Biological Trace Element Research , vol.127 , pp. 45-52
    • Ozcelik, D.1    Uzun, H.2
  • 26
    • 77950808419 scopus 로고    scopus 로고
    • Consideration of the ischaemic basis and treatment of Alzheimer's disease
    • Pluta R., Ulamek M., Jablonski M. Consideration of the ischaemic basis and treatment of Alzheimer's disease. Folia Neuropathologica 2010, 48:11-26.
    • (2010) Folia Neuropathologica , vol.48 , pp. 11-26
    • Pluta, R.1    Ulamek, M.2    Jablonski, M.3
  • 27
    • 79955642440 scopus 로고    scopus 로고
    • The effect of metals on spatial memory in a transgenic mouse model of Alzheimer's disease
    • Railey A.M., Groeber C.M., Flinn J.M. The effect of metals on spatial memory in a transgenic mouse model of Alzheimer's disease. Journal of Alzheimer's Disease 2011, 24:375-381.
    • (2011) Journal of Alzheimer's Disease , vol.24 , pp. 375-381
    • Railey, A.M.1    Groeber, C.M.2    Flinn, J.M.3
  • 28
    • 67149139988 scopus 로고    scopus 로고
    • The role of vascular factors in late-onset sporadic Alzheimer's disease. Genetic and molecular aspects
    • Rocchi A., Orsucci D., Tognoni G., Ceravolo R., Siciliano G. The role of vascular factors in late-onset sporadic Alzheimer's disease. Genetic and molecular aspects. Current Alzheimer's Research 2009, 6:224-237.
    • (2009) Current Alzheimer's Research , vol.6 , pp. 224-237
    • Rocchi, A.1    Orsucci, D.2    Tognoni, G.3    Ceravolo, R.4    Siciliano, G.5
  • 29
    • 0035950225 scopus 로고    scopus 로고
    • Clearing the brain's amyloid cobwebs
    • Selkoe D.J. Clearing the brain's amyloid cobwebs. Neuron 2001, 32:177-180.
    • (2001) Neuron , vol.32 , pp. 177-180
    • Selkoe, D.J.1
  • 30
    • 33947383715 scopus 로고    scopus 로고
    • Copper and clioquinol treatment in young APP transgenic and wild-type mice: effects on life expectancy, body weight, and metal-ion levels
    • Schäfer S., Pajonk F.G., Multhaup G., Bayer T.A. Copper and clioquinol treatment in young APP transgenic and wild-type mice: effects on life expectancy, body weight, and metal-ion levels. Journal of Molecular Medicine (Berlin) 2007, 85:405-413.
    • (2007) Journal of Molecular Medicine (Berlin) , vol.85 , pp. 405-413
    • Schäfer, S.1    Pajonk, F.G.2    Multhaup, G.3    Bayer, T.A.4
  • 31
    • 33645554445 scopus 로고    scopus 로고
    • Effects of amelioration of total flavonoids from stems and leaves of Scutellaria baicalensis Georgi on cognitive deficits, neuronal damage and free radicals disorder induced by cerebral ischemia in rats
    • Shang Y.Z., Miao H., Cheng J.J., Qi J.M. Effects of amelioration of total flavonoids from stems and leaves of Scutellaria baicalensis Georgi on cognitive deficits, neuronal damage and free radicals disorder induced by cerebral ischemia in rats. Biological and Pharmaceutical Bulletin 2006, 29:805-810.
    • (2006) Biological and Pharmaceutical Bulletin , vol.29 , pp. 805-810
    • Shang, Y.Z.1    Miao, H.2    Cheng, J.J.3    Qi, J.M.4
  • 33
    • 4444276735 scopus 로고    scopus 로고
    • Clearance of Alzheimer's Abeta peptide: the many roads to perdition
    • Tanzi R.E., Moir R.D., Wagner S.L. Clearance of Alzheimer's Abeta peptide: the many roads to perdition. Neuron 2004, 43:605-608.
    • (2004) Neuron , vol.43 , pp. 605-608
    • Tanzi, R.E.1    Moir, R.D.2    Wagner, S.L.3
  • 35
    • 74049090496 scopus 로고    scopus 로고
    • Alterations in mRNA expression of BACE1, cathepsin B, and glutaminyl cyclase in mice ischemic brain
    • Ye J.T., Pi R.B., Mao X.X., Chen X.H., Qin J., Xu S.W., Liu P.Q. Alterations in mRNA expression of BACE1, cathepsin B, and glutaminyl cyclase in mice ischemic brain. Neuroreport 2009, 20:1456-1460.
    • (2009) Neuroreport , vol.20 , pp. 1456-1460
    • Ye, J.T.1    Pi, R.B.2    Mao, X.X.3    Chen, X.H.4    Qin, J.5    Xu, S.W.6    Liu, P.Q.7
  • 36
    • 34249337528 scopus 로고    scopus 로고
    • Iron dysregulation in Alzheimer's disease: multimodal brain permeable iron chelating drugs, possessing neuroprotective-neurorescue and amyloid precursor protein-processing regulatory activities as therapeutic agents
    • Youdim M.B.H., Mandel S., Amit T., Bar-Am O. Iron dysregulation in Alzheimer's disease: multimodal brain permeable iron chelating drugs, possessing neuroprotective-neurorescue and amyloid precursor protein-processing regulatory activities as therapeutic agents. Progress in Neurobiology 2007, 82:348-360.
    • (2007) Progress in Neurobiology , vol.82 , pp. 348-360
    • Youdim, M.B.H.1    Mandel, S.2    Amit, T.3    Bar-Am, O.4
  • 37
    • 33750503794 scopus 로고    scopus 로고
    • Fermented papaya preparation attenuates beta-amyloid precursor protein: beta-amyloid-mediated copper neurotoxicity in beta-amyloid precursor protein and beta-amyloid precursor protein Swedish mutation overexpressing SH-SY5Y cells
    • Zhang J., Mori A., Chen Q., Zhao B. Fermented papaya preparation attenuates beta-amyloid precursor protein: beta-amyloid-mediated copper neurotoxicity in beta-amyloid precursor protein and beta-amyloid precursor protein Swedish mutation overexpressing SH-SY5Y cells. Neuroscience 2006, 143:63-72.
    • (2006) Neuroscience , vol.143 , pp. 63-72
    • Zhang, J.1    Mori, A.2    Chen, Q.3    Zhao, B.4


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