-
1
-
-
34347332411
-
The role of metals in the etiology of Alzheimer's disease
-
Free Radicals and Cell Signaling in Alzheimer's
-
Shcherbatykh I, Carpenter DO (2007) The role of metals in the etiology of Alzheimer's disease. J Alzheimers Dis11, 191-205. (Pubitemid 47010984)
-
(2007)
Journal of Alzheimer's Disease
, vol.11
, Issue.2
, pp. 191-205
-
-
Shcherbatykh, I.1
Carpenter, D.O.2
-
2
-
-
1842504323
-
Redox-active metals, oxidative stress, and Alzheimer's disease pathology
-
DOI 10.1196/annals.1306.012
-
Huang X, Moir RD, Tanzi RE, Bush AI, Rogers JT (2004) Redox-active metals, oxidative stress, and Alzheimer's dis-ease pathology. Ann N YAcad Sci 1012, 153-163. (Pubitemid 38453522)
-
(2004)
Annals of the New York Academy of Sciences
, vol.1012
, pp. 153-163
-
-
Huang, X.1
Moir, R.D.2
Tanzi, R.E.3
Bush, A.I.4
Rogers, J.T.5
-
3
-
-
0032507975
-
Copper, iron and zinc in Alzheimer's disease senile plaques
-
DOI 10.1016/S0022-510X(98)00092-6, PII S0022510X98000926
-
Lovell MA, Robertson JD, Teesdale WJ, Campbell JL, Markesbery WR (1998) Copper, iron, and zincin Alzheimer's disease senile plaques. J Neurol Sci 158, 47-52. (Pubitemid 28277534)
-
(1998)
Journal of the Neurological Sciences
, vol.158
, Issue.1
, pp. 47-52
-
-
Lovell, M.A.1
Robertson, J.D.2
Teesdale, W.J.3
Campbell, J.L.4
Markesbery, W.R.5
-
4
-
-
0033986037
-
Histochemically-reactive zinc in amyloid plaques, angiopathy, and degenerating neurons of Alzheimer's diseased brains
-
DOI 10.1016/S0006-8993(99)02096-X, PII S000689939902096X
-
Suh SW, Jensen KB, Jensen MS, Silva DS, Kesslak PJ, Danscher G, Frederickson CJ (2000) Histochemically-reactive zinc in amyloid plaques, angiopathy, and degenerat-ing neurons of Alzheimer's diseased brains. Brain Res 852, 274-278. (Pubitemid 30035163)
-
(2000)
Brain Research
, vol.852
, Issue.2
, pp. 274-278
-
-
Suh, S.W.1
Jensen, K.B.2
Jensen, M.S.3
Silva, D.S.4
Kesslak, P.J.5
Danscher, G.6
Frederickson, C.J.7
-
5
-
-
17644397044
-
Histological co-localization of iron in Aβ plaques of PS/APP transgenic mice
-
DOI 10.1007/s11064-004-2442-x
-
Falangola MF, Lee SP, Nixon RA, Duff K, Helpern JA (2005) Histological co-localization of iron in Abeta plaques of PS/APP transgenic mice. Neurochem Res 30, 201-205. (Pubitemid 40569203)
-
(2005)
Neurochemical Research
, vol.30
, Issue.2
, pp. 201-205
-
-
Falangola, M.F.1
Lee, S.-P.2
Nixon, R.A.3
Duff, K.4
Helpern, J.A.5
-
6
-
-
0027220686
-
A novel zinc(II) binding site modulates the function of the βA4 amyloid protein precursor of Alzheimer's disease
-
Bush AI, Multhaup G, Moir RD, Williamson TG, Small DH, Rumble B, Pollwein P, Beyreuther K, Masters CL (1993) A novel zinc (II) binding site modulates the function of the ßA4 amyloid protein precursor of Alzheimer's disease. JBiol Chem268, 16109-16112. (Pubitemid 23229904)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.22
, pp. 16109-16112
-
-
Bush, A.I.1
Multhaup, G.2
Moir, R.D.3
Williamson, T.G.4
Small, D.H.5
Rumble, B.6
Pollwein, P.7
Beyreuther, K.8
Masters, C.L.9
-
7
-
-
0028177269
-
The betaA4 amyloid precursor protein biding to copper
-
Hesse L, Beher D, Masters CL, Multhaup G (1994) The betaA4 amyloid precursor protein biding to copper. FEBS Letters 349, 109-116.
-
(1994)
FEBS Letters
, vol.349
, pp. 109-116
-
-
Hesse, L.1
Beher, D.2
Masters, C.L.3
Multhaup, G.4
-
8
-
-
12144282992
-
Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer's Aβ peptides
-
DOI 10.1007/s00775-004-0602-8
-
Huang X, Atwood CS, Moir RD, Hartshorn MA, Tanzi RE, Bush AI (2004) Trace metal contamination initiates the appar-ent auto-aggregation, amyloidosis, and oligomerization of Alzheimer's Abeta peptides. J Biol Inorg Chem 9, 954-960. (Pubitemid 40109902)
-
(2004)
Journal of Biological Inorganic Chemistry
, vol.9
, Issue.8
, pp. 954-960
-
-
Huang, X.1
Atwood, C.S.2
Moir, R.D.3
Hartshorn, M.A.4
Tanzi, R.E.5
Bush, A.I.6
-
9
-
-
0035865905
-
Redox-active iron mediates amyloid-β toxicity
-
DOI 10.1016/S0891-5849(00)00494-9, PII S0891584900004949
-
Rottkamp CA, Raina AK, Zhu X, Gaier E, Bush AI, Atwood CS, Chevion M, Perry G, Smith MA (2001) Redox-active iron mediates amyloid-beta toxicity. Free Radic Biol Med 30, 447-450. (Pubitemid 32155543)
-
(2001)
Free Radical Biology and Medicine
, vol.30
, Issue.4
, pp. 447-450
-
-
Rottkamp, C.A.1
Raina, A.K.2
Zhu, X.3
Gaier, E.4
Bush, A.I.5
Atwood, C.S.6
Chevion, M.7
Perry, G.8
Smith, M.A.9
-
10
-
-
0028180196
-
Modulation of Aß adhesiveness and secretase site cleavage by zinc
-
Bush AI, Pettingell WH, Multhaup G (1994) Modulation of Aß adhesiveness and secretase site cleavage by zinc J Biol Chem269, 12152-12158.
-
(1994)
J Biol Chem
, vol.269
, pp. 12152-12158
-
-
Bush, A.I.1
Pettingell, W.H.2
Multhaup, G.3
-
11
-
-
0032557425
-
Dramatic aggregation of alzheimer by Cu(II) is induced by conditions representing physiological acidosis
-
DOI 10.1074/jbc.273.21.12817
-
Atwood CS, Moir RD, Huang X, Scarpa RC, Bacarra NM, Romano DM, Hartshorn MA, Tanzi RE, Bush, AI (1998) Dra-matic aggregation of Alzheimer Aß by Cu(II) is induced by conditions representing physiological acidosis. J Biol Chem 273, 12817-12826. (Pubitemid 28246837)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.21
, pp. 12817-12826
-
-
Atwood, C.S.1
Moir, R.D.2
Huang, X.3
Scarpa, R.C.4
Bacarra, N.M.E.5
Romano, D.M.6
Hartshorn, M.A.7
Tanzi, R.E.8
Bush, A.I.9
-
12
-
-
3042666730
-
42 in a manner which may have consequences for metal chelation therapy in Alzheimer's disease
-
House E, Collingwood J, Khan A, Korchazkina O, Berthon G, Exley C (2004) Aluminum, iron, zinc and copper influence the in vitro formation of amyloid fibrils of Aß42 in a manner which may have consequences for metal chelation therapy in Alzheimer's disease. J AlzheimersDis 6, 291-301. (Pubitemid 38823264)
-
(2004)
Journal of Alzheimer's Disease
, vol.6
, Issue.3
, pp. 291-301
-
-
House, E.1
Collingwood, J.2
Khan, A.3
Korchazkina, O.4
Berthon, G.5
Exley, C.6
-
13
-
-
43049150678
-
Metals in Alzheimer's and Parkinson's disease
-
Barnham KJ, Bush AI (2008) Metals in Alzheimer's and Parkinson's disease. Curr Op Chem Biol 12, 222-228.
-
(2008)
Curr Op Chem Biol
, vol.12
, pp. 222-228
-
-
Barnham, K.J.1
Bush, A.I.2
-
14
-
-
18344414746
-
The Aβ peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction
-
DOI 10.1021/bi990438f
-
Huang X, Atwood CS, Hartshorn MA, Multhaup G, Goldstein LE, Scarpa RC, Cuajungco MP, Gray DN, Lim J, Moir RD, Tanzi RE, Bush AI (1999) The A beta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction. Biochemistry 38, 7609-7616. (Pubitemid 29289332)
-
(1999)
Biochemistry
, vol.38
, Issue.24
, pp. 7609-7616
-
-
Huang, X.1
Atwood, C.S.2
Hartshorn, M.A.3
Multhaup, G.4
Goldstein, L.E.5
Scarpa, R.C.6
Cuajungco, M.P.7
Gray, D.N.8
Lim, J.9
Moir, R.D.10
Tanzi, R.E.11
Bush, A.I.12
-
15
-
-
0037386086
-
The metallobiology of Alzheimer's disease
-
DOI 10.1016/S0166-2236(03)00067-5
-
Bush AI (2003) The metallobiology of Alzheimer's disease. Trends Neurosci 26, 207-214. (Pubitemid 36412003)
-
(2003)
Trends in Neurosciences
, vol.26
, Issue.4
, pp. 207-214
-
-
Bush, A.I.1
-
16
-
-
0026635457
-
Iron regulation in the brain: Histochemical, biochemical, and molecular considerations
-
Connor JR, Benkovic SA (1992) Iron regulation in the brain: histochemical, biochemical, and molecular considerations. AnnNeurol 32, S51-S61.
-
(1992)
AnnNeurol
, vol.32
-
-
Connor, J.R.1
Benkovic, S.A.2
-
17
-
-
0026590705
-
Regional distribution of iron and iron-regulatory proteins in the brain in aging and Alzheimer's disease
-
Connor JR, Snyder BS, Beard JL, Fine RE, MufsonEJ (1992) Regional distribution of iron and iron-regulatory proteins in the brain in aging and Alzheimer's disease. J Neurosci Res 31, 327-335.
-
(1992)
J Neurosci Res
, vol.31
, pp. 327-335
-
-
Connor, J.R.1
Snyder, B.S.2
Beard, J.L.3
Fine, R.E.4
Mufson, E.J.5
-
18
-
-
0033949740
-
Effect of zinc ions on the cytotoxicity induced by the amyloid β- peptide
-
Moreira P, Pereira C, Santos MS, Oliveira C (2000) Effect of zinc ions on the cytotoxicity induced by the amyloid-beta peptide. Antioxid Redox Signal 2, 317-325. (Pubitemid 30445942)
-
(2000)
Antioxidants and Redox Signaling
, vol.2
, Issue.2
, pp. 317-325
-
-
Moreira, P.1
Pereira, C.2
Santos, M.S.3
Oliveira, C.4
-
21
-
-
0034733705
-
Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of Aß
-
Cuajungco MP, Goldstein LE, Nunomura A, Smith MA, Lim JT, Atwood CS, Huang X, Farrag YW, Perry G, Bush AI (2000) Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of Aß by zinc J Biol Chem 275, 19438-19442.
-
(2000)
By Zinc J Biol Chem
, vol.275
, pp. 19438-19442
-
-
Cuajungco, M.P.1
Goldstein, L.E.2
Nunomura, A.3
Smith, M.A.4
Lim, J.T.5
Atwood, C.S.6
Huang, X.7
Farrag, Y.W.8
Perry, G.9
Bush, A.I.10
-
22
-
-
0037188530
-
Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice
-
DOI 10.1073/pnas.092034699
-
Lee JY, Cole TB, Palmiter RD, Suh SW, Koh JY (2002) Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice. Proc Natl Acad Sci USA 99, 7705-7710. (Pubitemid 34568755)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.11
, pp. 7705-7710
-
-
Lee, J.-Y.1
Cole, T.B.2
Palmiter, R.D.3
Suh, S.W.4
Koh, J.-Y.5
-
23
-
-
32544436616
-
Zinc dyshomeostasis: A key modulator of neuronal injury
-
Dedicated to Prof.Marino Nicolini
-
Capasso M, Jeng JM, Malavolta M, Mocchegiani E, Sensi SL (2005) Zinc dyshomeostasis: a key modulator of neuronal injury. J AlzheimersDis 8, 93-108. (Pubitemid 43230132)
-
(2005)
Journal of Alzheimer's Disease
, vol.8
, Issue.2
, pp. 93-108
-
-
Capasso, M.1
Jeng, J.-M.2
Malavolta, M.3
Mocchegiani, E.4
Sensi, S.L.5
-
24
-
-
0033430087
-
Copper inhibits β-amyloid production and stimulates the non-amyloidogenic pathway of amyloid-precursor-protein secretion
-
DOI 10.1042/0264-6021:3440461
-
Borchardt T, Camakaris J, Cappai R, Masters CL, Beyreuther K, Multhaup G (1999) Copper inhibits beta-amyloid production and stimulates the non-amyloidogenic pathway of amyloid-precursor-protein secretion. Biochem J 344, 461-467. (Pubitemid 30011603)
-
(1999)
Biochemical Journal
, vol.344
, Issue.2
, pp. 461-467
-
-
Borchardt, T.1
Camakaris, J.2
Cappai, R.3
Masters, C.L.4
Beyreuther, K.5
Multhaup, G.6
-
25
-
-
43549091337
-
Intracellular copper deficiency increases amyloid-β secretion by diverse mechanisms
-
DOI 10.1042/BJ20080103
-
Cater M, McInnes K, Li Q-X, Volitakis I, La Fontaine S, Mercer J, Bush AI (2008) Intracellular copper deficiency increases amyloid-beta secretion by diverse mechanisms. Biochem J412, 141-152. (Pubitemid 351678344)
-
(2008)
Biochemical Journal
, vol.412
, Issue.1
, pp. 141-152
-
-
Cater, M.A.1
McInnes, K.T.2
Li, Q.-X.3
Volitakis, I.4
Fontaine, S.L.A.5
Mercer, J.F.B.6
Bush, A.I.7
-
26
-
-
0034875441
-
Low dietary zinc alters indices of copper function and status in postmenopausal women
-
DOI 10.1016/S0899-9007(01)00560-3, PII S0899900701005603
-
Milne DB, Davis CD, Nielsen FH (2001) Low dietary zinc alters indices of copper function and status in postmenopausal women. Nutrition 17, 701-708. (Pubitemid 32816315)
-
(2001)
Nutrition
, vol.17
, Issue.9
, pp. 701-708
-
-
Milne, D.B.1
Davis, C.D.2
Nielsen, F.H.3
-
27
-
-
33646036991
-
Zinc requirements and the risks and benefits of zinc supplementation
-
Maret W, Sandstead HH (2006) Zinc requirements and the risks and benefits of zinc supplementation. J Trace Elem Med Biol 20, 3-18.
-
(2006)
J Trace Elem Med Biol
, vol.20
, pp. 3-18
-
-
Maret, W.1
Sandstead, H.H.2
-
28
-
-
11844298397
-
Enhanced zinc consumption causes memory deficits and increased brain levels of zinc
-
DOI 10.1016/j.physbeh.2004.10.009, PII S0031938404004494
-
Flinn JM, Hunter D, Linkous DH, Lanzirotti A, Smith L, Brightwell J, Jones BF (2005) Enhanced zinc consumption causes memory deficits and increased brain levels of zinc Physiol Behav 83, 793-803. (Pubitemid 40091613)
-
(2005)
Physiology and Behavior
, vol.83
, Issue.5
, pp. 793-803
-
-
Flinn, J.M.1
Hunter, D.2
Linkous, D.H.3
Lanzirotti, A.4
Smith, L.N.5
Brightwell, J.6
Jones, B.F.7
-
29
-
-
31744436378
-
Effects of enhanced zinc and copper in drinking water on spatial memory and fear conditioning
-
DOI 10.1016/j.gexplo.2005.08.019, PII S0375674205001093
-
Chrosniak LD, Smith LN, Flinn JM, McDonald C, Jones BF (2006) Effects of enhanced zinc and copper in drinking water on spatial memory and fear conditioning. J Geochem Explor 88, 91-94. (Pubitemid 43173807)
-
(2006)
Journal of Geochemical Exploration
, vol.88
, Issue.SPEC. ISS.
, pp. 91-94
-
-
Chrosniak, L.D.1
Smith, L.N.2
McDonald, C.G.3
Jones, B.F.4
Flinn, J.M.5
-
30
-
-
77950950391
-
Alterations in fear response and spatial memory in pre-and post-natal zinc supplemented rats: Remediation by copper
-
Railey AM, Micheli TL, Wanschura PB, Flinn JM (2010) Alterations in fear response and spatial memory in pre-and post-natal zinc supplemented rats: remediation by copper. Physiol Behav 2, 95-100.
-
(2010)
Physiol Behav
, vol.2
, pp. 95-100
-
-
Railey, A.M.1
Micheli, T.L.2
Wanschura, P.B.3
Flinn, J.M.4
-
31
-
-
72949112330
-
The effects of enhanced zinc on spatial memory and plaque formation in transgenic mice
-
Linkous DH, Adlard PA, Wanschura PB, Conko KM, Flinn JM (2009) The effects of enhanced zinc on spatial memory and plaque formation in transgenic mice. J Alzheimers Dis 18, 565-579.
-
(2009)
J Alzheimers Dis
, vol.18
, pp. 565-579
-
-
Linkous, D.H.1
Adlard, P.A.2
Wanschura, P.B.3
Conko, K.M.4
Flinn, J.M.5
-
32
-
-
75149117544
-
Cognitive effects of long term enhanced dietary zinc consumption: Modulation by copper
-
Program No. 265.10
-
Railey AM, Smith LN, Moran K, Veejay M, Fitzgerald A, Micheli T, Flinn JM, Jones BF, Chrosniak LD (2006) Cognitive effects of long term enhanced dietary zinc consumption: modulation by copper. Soc Neurosci Abstr, Program No. 265.10.
-
(2006)
Soc Neurosci Abstr
-
-
Railey, A.M.1
Smith, L.N.2
Moran, K.3
Veejay, M.4
Fitzgerald, A.5
Micheli, T.6
Flinn, J.M.7
Jones, B.F.8
Chrosniak, L.D.9
-
34
-
-
24644475272
-
Alzheimer disease β-amyloid activity mimics cholesterol oxidase
-
DOI 10.1172/JCI23610
-
Puglielli L, Friedlich AL, Setchell KD, Nagano S, Opazo C, Cherny RA, Barnham KJ, Wade JD, Melov S, Kovacs DM, Bush AI (2005) Alzheimer disease ß-amyloid activity mimics cholesterol oxidase. Clin Invest 115, 2556-2563 (Pubitemid 41266218)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.9
, pp. 2556-2563
-
-
Puglielli, L.1
Friedlich, A.L.2
Setchell, K.D.R.3
Nagano, S.4
Opazo, C.5
Cherny, R.A.6
Barnham, K.J.7
Wade, J.D.8
Melov, S.9
Kovacs, D.M.10
Bush, A.I.11
-
35
-
-
11844282820
-
Dietary copper deficiency reduces iron absorption and duodenal enterocyte Hephaestin protein in male and female rats
-
Reeves PG, DeMars LCS, Johnson WT, Lukaski HC (2005) Dietary copper deficiency reduces iron absorption and duo-denal enterocyte hephaestin protein in male and female rats. J Nutrition 135, 92-98. (Pubitemid 40094327)
-
(2005)
Journal of Nutrition
, vol.135
, Issue.1
, pp. 92-98
-
-
Reeves, P.G.1
DeMars, L.C.S.2
Johnson, W.T.3
Lukaski, H.C.4
-
36
-
-
3543082198
-
Copper deficiency reduces iron absorption and biological half-life in male rats
-
Reeves P, DeMars L (2004) Copper deficiency reduces iron absorption and biological half-life in male rats. J Nutrition 134, 1953-1957. (Pubitemid 39031323)
-
(2004)
Journal of Nutrition
, vol.134
, Issue.8
, pp. 1953-1957
-
-
Reeves, P.G.1
DeMars, L.C.S.2
-
37
-
-
70350720293
-
Prevalence and associated risk factors of anemia in children and adoles-cents with intellectual disabilities
-
Lin JD, Lin PY, Lin LP, Hsu SW, Loh CH, Yen CF, Fang WH, Chien WC, Tang CC, Wu CL (2010) Prevalence and associated risk factors of anemia in children and adoles-cents with intellectual disabilities. Res Dev Disabil 31, 25-32.
-
(2010)
Res Dev Disabil
, vol.31
, pp. 25-32
-
-
Lin, J.D.1
Lin, P.Y.2
Lin, L.P.3
Hsu, S.W.4
Loh, C.H.5
Yen, C.F.6
Fang, W.H.7
Chien, W.C.8
Tang, C.C.9
Wu, C.L.10
-
39
-
-
70350576606
-
Long-term intake of a high zinc diet causes iron deficiency anemia accompa-nied by reticulocytosis and extra-medullary erythropoiesis
-
Yanagisawaa H, Miyakoshia Y, Kobayashia K, Sakaea K, Kawasakia I, Suzukia Y, Tamurab J (2009) Long-term intake of a high zinc diet causes iron deficiency anemia accompa-nied by reticulocytosis and extra-medullary erythropoiesis. Toxicol Lett 191, 15-19.
-
(2009)
Toxicol Lett
, vol.191
, pp. 15-19
-
-
Yanagisawaa, H.1
Miyakoshia, Y.2
Kobayashia, K.3
Sakaea, K.4
Kawasakia, I.5
Suzukia, Y.6
Tamurab, J.7
-
40
-
-
0036213748
-
The effect of five-year zinc supplementation on serum zinc, serum cholesterol and hematocrit in persons randomly assigned to treatment group in the age-related eye disease study: AREDS Report No. 7
-
Age-Related Eye Disease Study (AREDS) Research Group
-
Age-Related Eye Disease Study (AREDS) Research Group (2002) The effect of five-year zinc supplementation on serum zinc, serum cholesterol and hematocrit in persons randomly assigned to treatment group in the age-related eye disease study: AREDS Report No. 7. J Nutr 132, 697-670.
-
(2002)
J Nutr
, vol.132
, pp. 697-670
-
-
-
41
-
-
0029742199
-
Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice
-
DOI 10.1126/science.274.5284.99
-
Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Youkin S, Yang F, Cole G (1996) Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 274, 99-102. (Pubitemid 26332733)
-
(1996)
Science
, vol.274
, Issue.5284
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
42
-
-
0035065567
-
rd1) in FVB/N-derived transgenic mice
-
rd1) in FVB/N-derived transgenic mice. Lab Anim 35, 153-156.
-
(2000)
Lab Anim
, vol.35
, pp. 153-156
-
-
Giménez, E.1
Montoliu, L.2
-
43
-
-
0037160028
-
Overexpression of Alzheimer's disease amyloid-β opposes the age-dependent elevations of brain copper and iron
-
DOI 10.1074/jbc.M204379200
-
Maynard CJ, Cappai R, Volitakis I, Cherney RA, White AR, Beyreuther K, Masters CL, Bush AI, Li QX (2002) Over-expression of Alzheimer's disease amyloid-ß opposes the age-dependent elevations of brain copper and iron. J Biol Chem 277, 44670-44676. (Pubitemid 36159056)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.47
, pp. 44670-44676
-
-
Maynard, C.J.1
Cappai, R.2
Volitakis, I.3
Cherny, R.A.4
White, A.R.5
Beyreuther, K.6
Masters, C.L.7
Bush, A.I.8
Li, Q.-X.9
-
44
-
-
39849096023
-
Alzheimer's disease as copper deficiency
-
DOI 10.1016/j.mehy.2007.04.051, PII S0306987707005270
-
Klevay LM (2007) Alzheimer's disease as copper deficiency. Med Hypotheses 70, 802-807. (Pubitemid 351318084)
-
(2008)
Medical Hypotheses
, vol.70
, Issue.4
, pp. 802-807
-
-
Klevay, L.M.1
-
45
-
-
0033981049
-
In vivo evaluation of brain iron in Alzheimer disease using magnetic resonance imaging
-
Bartzokis G, Sultzer D, Cummings J, Holt LE, Hance DB, Henderson VW, Mintz J (2000) In vivo evaluation of brain iron in Alzheimer disease using magnetic resonance imaging. Arch Gen Psychiatry 57, 47-53. (Pubitemid 30035658)
-
(2000)
Archives of General Psychiatry
, vol.57
, Issue.1
, pp. 47-53
-
-
Bartzokis, G.1
Sultzer, D.2
Cummings, J.3
Holt, L.E.4
Hance, D.B.5
Henderson, V.W.6
Mintz, J.7
-
46
-
-
75149152568
-
Increasedironanfreeradical generation in preclinical Alzheimer disease and mild cogni-tive impairment
-
Smith MA, Zhu X, Tabaton M, Liu G, McKeel DW Jr, Cohen ML, Wang X, Siedlak SL, Dwyer BE, Hayashi T, Nakamura M, NunomuraA, Perry G (2010)Increasedironanfreeradical generation in preclinical Alzheimer disease and mild cogni-tive impairment. J AlzheimerDis 19, 363-372.
-
(2010)
J AlzheimerDis
, vol.19
, pp. 363-372
-
-
Smith, M.A.1
Zhu, X.2
Tabaton, M.3
Liu, G.4
McKeel Jr., D.W.5
Cohen, M.L.6
Wang, X.7
Siedlak, S.L.8
Dwyer, B.E.9
Hayashi, T.10
Nakamura, M.11
Nunomuraa Perry, G.12
-
47
-
-
12144282992
-
Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer's Aβ peptides
-
DOI 10.1007/s00775-004-0602-8
-
Huang X, Atwood CS, Moir RD, Hartshorn MA, Tanzi RE, Bush AI (2004) Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer's Aß peptides. J Biol Inorg Chem 9, 954-960. (Pubitemid 40109902)
-
(2004)
Journal of Biological Inorganic Chemistry
, vol.9
, Issue.8
, pp. 954-960
-
-
Huang, X.1
Atwood, C.S.2
Moir, R.D.3
Hartshorn, M.A.4
Tanzi, R.E.5
Bush, A.I.6
-
48
-
-
32444440545
-
Is zinc the link between compromises of brain perfusion (excitotoxicity) and Alzheimer's disease?
-
Dedicated to Prof.Marino Nicolini
-
Frederickson CJ, Cuajungco MP, Frederickson CJ (2005) Is zinc the link between compromises of brain perfusion (exci-totoxicity) and Alzheimer's disease? J Alzheimers Dis 8, 155-160. (Pubitemid 43227162)
-
(2005)
Journal of Alzheimer's Disease
, vol.8
, Issue.2
, pp. 155-160
-
-
Frederickson, C.J.1
Cuajungco, M.P.2
Frederickson, C.J.3
-
49
-
-
77956647381
-
Iron-export ferroxidase activity of ß-Amyloid precur-sor protein is inhibited by zinc in Alzheimer's disease
-
Duce JA, Tsatsanis A, Cater MA, James SA, Robb E, Wikhe K, Leong SL, Perez K, Johanssen T, Greenough MA, Cho H-H, Galatis D, Moir RD, Masters CI, McLean C, Tanzi RE, Cappai R, Barnham KJ, Ciccotosto GD, Rogers JT, Bush AI (2010) Iron-export ferroxidase activity of ß-Amyloid precur-sor protein is inhibited by zinc in Alzheimer's disease. Cell 142, 857-867.
-
(2010)
Cell
, vol.142
, pp. 857-867
-
-
Duce, J.A.1
Tsatsanis, A.2
Cater, M.A.3
James, S.A.4
Robb, E.5
Wikhe, K.6
Leong, S.L.7
Perez, K.8
Johanssen, T.9
Greenough, M.A.10
Cho, H.-H.11
Galatis, D.12
Moir, R.D.13
Masters, C.I.14
McLean, C.15
Tanzi, R.E.16
Cappai, R.17
Barnham, K.J.18
Ciccotosto, G.D.19
Rogers, J.T.20
Bush, A.I.21
more..
-
50
-
-
0036860349
-
Metal complexing agents as therapies for Alzheimer's disease
-
DOI 10.1016/S0197-4580(02)00120-3, PII S0197458002001203
-
Bush AI (2002) Metal complexing agents as therapies for Alzheimer's disease. Neurobiol Aging 23, 1031-1038. (Pubitemid 35447784)
-
(2002)
Neurobiology of Aging
, vol.23
, Issue.6
, pp. 1031-1038
-
-
Bush, A.I.1
-
51
-
-
10744228112
-
In vivo reduction of amyloid-β by a mutant copper transporter
-
DOI 10.1073/pnas.2332851100
-
Phinney AL, Drisaldi B, Schmidt SD, Lugowski S, Coronado V, Liang Y, Horne P, Yang J, Sekoulidis J, Coomaraswamy J, Chishti MA, Cox DW, Mathews PM, Nixon RA, Carlson GA, St George-Hyslop P, Westaway D (2003) In vivo reduction of amyloid-beta by a mutant copper transporter. Proc Natl Acad Sci USA 100, 14193-14198. (Pubitemid 37499213)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.SUPPL. 2
, pp. 14193-14198
-
-
Phinney, A.L.1
Drisaldi, B.2
Schmidt, S.D.3
Lugowski, S.4
Coronado, V.5
Liang, Y.6
Horne, P.7
Yang, J.8
Sekoulidis, J.9
Coomaraswamy, J.10
Chishti, M.A.11
Cox, D.W.12
Mathews, P.M.13
Nixon, R.A.14
Carlson, G.A.15
St. George-Hyslop, P.16
Westaway, D.17
-
52
-
-
10744226316
-
Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Aβ production in APP23 transgenic mice
-
DOI 10.1073/pnas.2332818100
-
Bayer TA, Schafer S, Simons A, Kemmling A, Kamer T, Tepest R, Eckert A, Schüssel K, Eikenberg O, Sturchler-Pierrat C, Abramowski D, Staufenbiel M, Multhaup G (2003) Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Abeta production in APP23 transgenic mice. Proc Nat Acad Sci USA 100, 14187-14192. (Pubitemid 37499212)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.SUPPL. 2
, pp. 14187-14192
-
-
Bayer, T.A.1
Schafer, S.2
Simons, A.3
Kemmling, A.4
Kamer, T.5
Tepest, R.6
Eckert, A.7
Schussel, K.8
Eikenberg, O.9
Sturchler-Pierrat, C.10
Abramowski, D.11
Staufenbiel, M.12
Multhaup, G.13
-
53
-
-
33749534285
-
Role of the Menkes copper-transporting ATPase in NMDA receptor-mediated neuronal toxicity
-
DOI 10.1073/pnas.0605390103
-
Schlief ML, West T, Craig AM, Holtzman DM, Gitlin JD (2006) Role of Menkes copper-transporting ATPase in NMDA receptor-mediated neuronal toxicity. Proc Natl Acad Sci USA 103, 14919-14924. (Pubitemid 44527829)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.40
, pp. 14919-14924
-
-
Schlief, M.L.1
West, T.2
Craig, A.M.3
Holtzman, D.M.4
Gitlin, J.D.5
-
54
-
-
77950360800
-
Trace Cop-per(II) or Zinc(II) ions drastically modify the aggregation behavior of amyloid-beta 1-42: An AMF study
-
Innocenti M, Guidotti M, Casini A, Bellandi S, Foresti ML, Gabbiani C, Pozzi A, Zatta P, Messori L (2010) Trace Cop-per(II) or Zinc(II) ions drastically modify the aggregation behavior of amyloid-beta 1-42: an AMF study. J Alzheimers Dis 19, 1323-1329.
-
(2010)
J Alzheimers Dis
, vol.19
, pp. 1323-1329
-
-
Innocenti, M.1
Guidotti, M.2
Casini, A.3
Bellandi, S.4
Foresti, M.L.5
Gabbiani, C.6
Pozzi, A.7
Zatta, P.8
Messori, L.9
|